We narrowed to 350 results for: Library

1. Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

   Pooled Library

   #138015

   Purpose

   This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.

   Depositor

   William Pu

   Article

   VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi

   Species

   Mus musculus

   Use

   AAV, CRISPR, and Cre/Lox

   Available since

   April 17, 2020

   Availability

   Academic Institutions and Nonprofits only

2. CRISPRi non-coding library (CRiNCL) - Unique to iPSC

   Pooled Library

   #86540

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

3. CRISPRi non-coding library (CRiNCL) - Unique to U87

   Pooled Library

   #86542

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

4. CHyMErA Large-Scale Exon Deletion hgRNA Library

   Pooled Library

   #209736

   Purpose

   CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

5. CRISPRi non-coding library (CRiNCL) - Unique to MCF7

   Pooled Library

   #86546

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

6. CRISPRi non-coding library (CRiNCL) - U87 & HEK293T

   Pooled Library

   #86547

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

7. CRISPRi non-coding library (CRiNCL) - K562 & HeLa

   Pooled Library

   #86549

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

8. CRISPRi non-coding library (CRiNCL) - Unique to HeLa

   Pooled Library

   #86545

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

9. Oxford Drosophila melanogaster Genome-wide CRISPR Library

   Pooled Library

   #64750

   Purpose

   A genome-wide CRISPR library covering 13,501 genes (98.8% of the Drosophila melanogaster genome), among which 8,989 genes are targeted by three or more independent single guide RNAs (sgRNAs).

   Depositor

   Ji-Long Liu

   Article

   Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

   Expression

   Insect

   Species

   Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

   Use

   CRISPR

   Available since

   March 7, 2016

   Availability

   Academic Institutions and Nonprofits only

10. Self-targeting epegRNA library, Tiled edits (lRM001)

    Pooled Library

    #227708

    Purpose

    CRISPR guide RNA library for prime editing

    Depositor

    Brittany Adamson

    Article

    Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    Jan. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

11. Human ABC Transporter Knockout Sub-library with UMIs

    Pooled Library

    #221410

    Purpose

    gRNA library to test the impact of transporters on biological processes (subset: ABC transporters and controls)

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

12. Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3

    Pooled Library

    #101934

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

13. Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

    Pooled Library

    #1000000083

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human kinome

    Depositor

    David Root, John Doench

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

14. Human SAM library in lenti sgRNA(MS2)_puro backbone

    Pooled Library

    #1000000074

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Feng Zhang

    Available since

    March 17, 2016

    Availability

    Academic Institutions and Nonprofits only

15. Human genome-wide lentiviral CRISPR gRNA library version 1

    Pooled Library

    #67989

    Purpose

    Human genome-wide CRISPR guide RNA library V1 (pKLV2-U6gRNA5(HumanV1)-PGKpuro2ABFP-W)

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

16. Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75317

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

17. Xiaole Shirley Liu lab Human CRISPR lentiviral library

    Pooled Library

    #1000000132

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Xiaole Shirley Liu

    Available since

    June 13, 2018

    Availability

    Academic Institutions and Nonprofits only

18. Human DNA Binding Domain-Focused CRISPR Knockout Library

    Pooled Library

    #123334

    Purpose

    Expresses gRNA targeting the DNA binding domain of human transcription factors.

    Depositor

    Christopher Vakoc

    Article

    Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 2, 2019

    Availability

    Academic Institutions and Nonprofits only

19. Mouse genome-wide lentiviral CRISPR gRNA library version 2

    Pooled Library

    #67988

    Purpose

    Mouse genome-wide CRISPR guide RNA library V2. (pKLV2-U6gRNA5(MouseV2)-PGKpuro2ABFP-W)

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

20. Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis

    Pooled Library

    #101930

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only