1,043 results

1. pAAV.hSyn.iGluSnFr.WPRE.SV40 (AAV1)

   Viral Prep

   #98929-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSyn.iGluSnFr.WPRE.SV40 (#98929). In addition to the viral particles, you will also receive purified pAAV.hSyn.iGluSnFr.WPRE.SV40 plasmid DNA. Synapsin-driven, iGluSnFr glutamate sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Marvin et al Nat Methods. 2013 Feb;10(2):162-70. doi:

   Promoter

   Syn

   Tags

   None

   Available Since

   Feb. 27, 2018

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-EF1a-C-CreintG (AAV1)

   Viral Prep

   #69571-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-EF1a-C-CreintG (#69571). In addition to the viral particles, you will also receive purified pAAV-EF1a-C-CreintG plasmid DNA. EF1a-driven expression of optimized C-terminal component of Cre recombinase dependent on GFP (Cre-DOG OPT); to be coinjected with pAAV-EF1a-N-CretrcintG (Addgene catalog# 69570) and GFP (or for use with transgenic GFP animals). These AAV preparations are suitable purity for injection into animals.

   Depositor

   Connie Cepko

   Article

   Tang et al Nat Neurosci. 2015 Sep;18(9):1334-41. do

   Promoter

   EF1a

   Tags

   None

   Available Since

   Feb. 19, 2020

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-EF1a-N-CretrcintG (AAV1)

   Viral Prep

   #69570-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-EF1a-N-CretrcintG (#69570). In addition to the viral particles, you will also receive purified pAAV-EF1a-N-CretrcintG plasmid DNA. EF1a-driven expression of optimized N-terminal component of Cre recombinase dependent on GFP (Cre-DOG OPT); to be coinjected with pAAV-EF1a-C-CreintG (Addgene catalog# 69571) and GFP (or for use with transgenic GFP animals). These AAV preparations are suitable purity for injection into animals.

   Depositor

   Connie Cepko

   Article

   Tang et al Nat Neurosci. 2015 Sep;18(9):1334-41. do

   Promoter

   EF1a

   Tags

   None

   Available Since

   Feb. 19, 2020

   Availability

   Academic Institutions and Nonprofits only

4. pTR-UF11 (AAV.A01.T)

   Viral Prep

   #157970-AAV.A01.T

   Purpose

   Ready-to-use AAV2 in TMN200 particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter

   Depositor

   Sergei Zolotukhin

   Article

   Burger et al Mol Ther. 2004 Aug;10(2):302-17. doi: 10

   Promoter

   chimeric CMV/Chicken Beta actin (CBA)

   Tags

   GFP

   Available Since

   Dec. 21, 2020

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-nEF-Con/Foff 2.0-ChR2-mCherry (AAV8)

   Viral Prep

   #137143-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-ChR2-mCherry (#137143). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-ChR2-mCherry plasmid DNA. nEF-driven, Cre-dependent expression of ChR2-mCherry for optogenetic activation (inhibited in the presence of Flp recombinase). These AAV preparations are suitable purity for injection into animals.

   Depositor

   INTRSECT 2.0 Project, Karl Deisseroth

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   mCherry (Cre-dependent)

   Available Since

   Feb. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

6. pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH (AAV9)

   Viral Prep

   #100049-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH (#100049). In addition to the viral particles, you will also receive purified pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH plasmid DNA. Synapsin-driven ChETA(E123T/H134R)-EYFP expression for optogenetic neural activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   Syn

   Tags

   EYFP

   Available Since

   Feb. 21, 2018

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-S5E6-dTom-nlsdTom (AAV1)

   Viral Prep

   #135641-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-S5E6-dTom-nlsdTom (#135641). In addition to the viral particles, you will also receive purified pAAV-S5E6-dTom-nlsdTom plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato in VIP cortical interneurons under the control of the E6 regulatory element. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Jordane Dimidschstein

   Article

   Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

   Promoter

   Tags

   dTomato

   Available Since

   Feb. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

8. pAAV-S5E2-Gq-P2A-dTomato (AAV1)

   Viral Prep

   #135635-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-S5E2-Gq-P2A-dTomato (#135635). In addition to the viral particles, you will also receive purified pAAV-S5E2-Gq-P2A-dTomato plasmid DNA. Expression of Gq-DREADD and dTomato (physically separate) under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Jordane Dimidschstein

   Article

   Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

   Promoter

   Tags

   dTomato (physically separate, not a fusion protein)

   Available Since

   Nov. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

9. pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S (AAV1)

   Viral Prep

   #106183-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S (#106183). In addition to the viral particles, you will also receive purified pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S plasmid DNA. Synapsin-driven, Cre-dependent SF-Venus-iGluSnFR.A184S glutamate sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

   Promoter

   Syn

   Tags

   Venus (Cre-dependent)

   Available Since

   Dec. 26, 2018

   Availability

   Academic Institutions and Nonprofits only

10. pAAV.hSyn1.Twitch2B.WPRE.SV40 (AAV1)

    Viral Prep

    #100040-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSyn1.Twitch2B.WPRE.SV40 (#100040). In addition to the viral particles, you will also receive purified pAAV.hSyn1.Twitch2B.WPRE.SV40 plasmid DNA. Synapsin-driven expression of (FRET)-based calcium biosensor Twitch2B. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Oliver Griesbeck

    Article

    Thestrup et al Nat Methods. 2014 Jan 5. doi: 10.1038/nm

    Promoter

    Syn

    Tags

    None

    Available Since

    March 8, 2018

    Availability

    Academic Institutions and Nonprofits only

11. pGP-AAV-CAG-FLEX-jGCaMP8s-WPRE (AAV Retrograde)

    Viral Prep

    #162380-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-CAG-FLEX-jGCaMP8s-WPRE (#162380). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP8s-WPRE plasmid DNA. CAG-driven, Cre-dependent expression of calcium sensor GCaMP8s (more sensitive). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Zhang et al Janelia Research Campus, Online Resource

    Promoter

    CAG

    Tags

    None

    Available Since

    June 22, 2021

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-CaMKIIa-hChR2(E123A)-mCherry (AAV9)

    Viral Prep

    #35506-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(E123A)-mCherry (#35506). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(E123A)-mCherry plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin E123A mutant fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

    Promoter

    CaMKII

    Tags

    mCherry

    Available Since

    March 30, 2018

    Availability

    Academic Institutions and Nonprofits only

13. pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (AAV8)

    Viral Prep

    #112677-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (#112677). In addition to the viral particles, you will also receive purified pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP plasmid DNA. EF1a-driven, Cre-dependent color switch. This AAV directs expression of nuclear mCherry in the absence of Cre. In the presence of Cre, nuclear EGFP (and not mCherry) will be expressed. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Brandon Harvey

    Article

    Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

    Promoter

    EF1a

    Tags

    mCherry (Cre-negative cells), EGFP (Cre-positive cells)

    Available Since

    Sept. 8, 2020

    Availability

    Academic Institutions and Nonprofits only

14. pAAV.CAG.iAChSnFR (AAV1)

    Viral Prep

    #137955-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.CAG.iAChSnFR (#137955). In addition to the viral particles, you will also receive purified pAAV.CAG.iAChSnFR plasmid DNA. CAG-driven iAChSnFR acetylcholine sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Borden et al bioRxiv 2020

    Promoter

    CAG

    Tags

    None

    Available Since

    Oct. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-hSyn1-eYFP (AAV2)

    Viral Prep

    #117382-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-hSyn1-eYFP (#117382). In addition to the viral particles, you will also receive purified pAAV-hSyn1-eYFP plasmid DNA. hSyn-driven eYFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Challis et al Nat Protoc. 2019 Feb;14(2):379-414. doi:

    Promoter

    Syn

    Tags

    eYFP

    Available Since

    Feb. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-Ef1a-mCherry (AAV1)

    Viral Prep

    #114470-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-Ef1a-mCherry (#114470). In addition to the viral particles, you will also receive purified pAAV-Ef1a-mCherry plasmid DNA. EF1a-driven mCherry expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    EF1a

    Tags

    mCherry

    Available Since

    Sept. 15, 2021

    Availability

    Academic Institutions and Nonprofits only

17. pGP-AAV-syn-flex-iGABASnFR2(no bind)-WPRE (AAV1)

    Viral Prep

    #218879-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-flex-iGABASnFR2(no bind)-WPRE (#218879). In addition to the viral particles, you will also receive purified pGP-AAV-syn-flex-iGABASnFR2(no bind)-WPRE plasmid DNA. Syn-driven, Cre-dependent expression of the improved GABA sensor control iGABASnFR2(no bind) (no change in fluorescence). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Kolb et al bioRxiv 2025.03.25.644953

    Promoter

    Syn

    Tags

    None

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

18. pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE (AAV PHP.eB)

    Viral Prep

    #104496-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE (#104496). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE plasmid DNA. CAG-driven, Cre-dependent jGCaMP7f calcium sensor. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    CAG

    Tags

    None

    Available Since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

19. AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3987) (AAV PHP.eB)

    Viral Prep

    #214851-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3987) (#214851). In addition to the viral particles, you will also receive purified AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3987) plasmid DNA. minBG-driven expression of jRGECO1a in striatal indirect pathway medium spiny neurons (D2 MSNs). These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    The Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Promoter

    Tags

    None

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-CAG-DIO-PPO-Venus (AAV5)

    Viral Prep

    #139504-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-CAG-DIO-PPO-Venus (#139504). In addition to the viral particles, you will also receive purified pAAV-CAG-DIO-PPO-Venus plasmid DNA. CAG-driven, Cre-dependent expression of Venus-tagged parapinopsin. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Michael Bruchas

    Article

    Copits et al Neuron. 2021 Jun 2;109(11):1791-1809.e11

    Promoter

    CAG

    Tags

    Venus

    Available Since

    April 10, 2024

    Availability

    Academic Institutions and Nonprofits only