We narrowed to 396 results for: ICL

1. Tips for Using FRET in Your Experiments

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   Blog Post

   ...Chemiluminescence Resonance Energy Transfer    Interesting Articles About FRET: Piston DW, Kremers GJ. Fluorescent...

2. Plasmids 101: The Promoter Region – Let's Go!

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   Blog Post

   ...Max Juchheim contributed to the writing of this article. Additional Resources on the Addgene Blog Browse...

3. Adeno-associated Viruses (AAVs) for Genome Editing

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   Blog Post

   ...Adeno-associated viruses (AAVs) make fantastic gene delivery vehicles for episomal gene expression and are particularly...

4. Antibodies 101: Introduction to Immunofluorescence

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   Blog Post

   ...proper experimental design are essential. In this article, we’ll go through some of the most important considerations...

5. Transferable Skills Guide: Time Management

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   Blog Post

   ...JUST GET STARTED - One Harvard Business Review article on procrastination recommends testing out how much...

6. Thoughts on the Future of Research 2015 Boston Symposium

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   Blog Post

   ... for PhDs or postdocs. Having this information publicly available may realign trainee expectations with...

7. Viral Vectors 101: AAV Serotypes and Tissue Tropism

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   Blog Post

   ...variations between serotypes can change how the viral particle sneaks its way into cells. Generally, AAV serotypes...

8. How to Design Your gRNA for CRISPR Genome Editing

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   Blog Post

   ...these subjects can be found in two recent review articles (Doench et al., 2017, and Hanna et al., 2020) ...

9. CRISPR 101: Epigenetics and Editing the Epigenome

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   Blog Post

   ...  Leah Schwiesow contributed to updating this article. References Haldeman JM, Conway AE, Arlotto ME,...

10. Antibodies 101: The Basics of Western Blotting

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    Blog Post

    ...tricks for molecular biology protocols Browse other articles related to antibodies Resources on Addgene.org...

11. Important Considerations When Using AAVs

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    Blog Post

    ...overall cell function. AAVs are the most appropriate vehicle for this type of research, as they are safe to ...

12. Tips for a 1st Time CRISPR User (by a 1st Time CRISPR User)

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    Blog Post

    ...service and the methods sections of scientific articles (gasp). To my delight, not only was I able to ...

13. Finding Your Science Policy Path

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    Blog Post

    ...answer about what science policy even is! In this article, I hope to provide a brief explainer of the who...

14. Deep Dive: Statistical Tests (Comparisons)

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    Blog Post

    ...statistical tests beyond the ones detailed in this article. These are just some of the most common parametric...

15. Antibodies 101: Antibody Engineering and Directed Evolution

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    Blog Post

    ...used directly as therapeutic agents or serve as vehicles for delivering other treatments, their efficacy...

16. Plasmids 101: Using Transposons in the Lab

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    Blog Post

    ...on DNA transposons for much of the rest of this article. Class I Transposable elements (TEs): Retrotransposons...

17. A Guide to Getting Started in Undergrad Research

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    Blog Post

    ...available resources! Many online resources and articles about careers in science are geared towards grad...

18. CRISPR Guide

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    Collection

    ...capabilities but are small enough to be packaged in AAV particles. Cas13 fusions have also been used in in vivo ...

19. Chemogenetics Guide

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    Guide

    ...respond specifically to the anti-smoking drug varenicline. This PSAM carries mutations at L131G, Q139L,...and is termed PSAM4 (or PSAM 4 ). Additional varenicline analogs, termed ultrapotent PSEMs (or uPSEMs)...Effect Outcome (in neurons) Reference PSAM4 Gly Varenicline, uPSEM 792, uPSEM 817 Cl - influx Neuronal inhibition...inhibition Magnus et al., 2019 PSAM4 5HT3 Varenicline, uPSEM 792, uPSEM 817 Na + , K + influx Neuronal...

20. Cancer and the Immune System: Deciphering the Relationship

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    Blog Post

    ...barricades put up by cancer. As mentioned in this article, cancers differ in practically every facet starting...