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We narrowed to 497 results for: LARGE

Showing: 361 - 380 of 497 results
  1. CRISPR 101: Off-Target Effects

    Type
    Blog Post
    ...frequency of 5%. Your experiment involves making a large sgRNA library to thousands of genes and targeting...
  2. Plasmids 101: Biotinylation

    Type
    Blog Post
    ...bind to your biotinylated antibody. This creates a large meshwork of biotin-avidin complexes bound to your...
  3. Pipetting Protocol

    Type
    Protocol
    ... liquid. Pro-Tip If pipetting from a relatively large container holding a small volume of liquid, tilt...
  4. Fluorescent Protein Guide: Biosensors

    Type
    Collection
    ... pathway or measurement of a biomolecule while largely preserving spatial and temporal cellular processes... Engineering of NEMO as calcium indicators with large dynamics and high sensitivity. Nat Methods. 2023...receptor Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation...
  5. 28 Hot Plasmid Technologies from 2015

    Type
    Blog Post
    ...modulate biological processes, but it did not show large changes in binding affinity with light stimulation...advantageous compared to other viral systems due to its large cargo capacity, minimal cytotoxicity, and broad ... CRISPR-Display uses the dCas9 enzyme to deploy large RNA cargos to specific DNA loci. In CRISPR-Display...
  6. CRISPR 101: Epigenetics and Editing the Epigenome

    Type
    Blog Post
    ...) NLS-Sa dCas9-NLS-LSD1. LSD1 is a particularly large protein, and this fusion allows for packaging into...genomic targets. These two vectors are part of the larger pMVP/pMAGIC cloning system, which contains Cas9...
  7. Hot Plasmids: February 2026

    Type
    Blog Post
    ...relies on the vault ribonucleoprotein complex: a large, barrel-shaped structure of unknown function that...
  8. Hot Plasmids: Fall 2025

    Type
    Blog Post
    ... With 143 plasmids deposited from this paper, a large menu of tool and control constructs is available...discovered that disruption of the nucleolus — the largest biomolecular condensate in human cells — causes...
  9. Deep Dive: Statistical Tests (Comparisons)

    Type
    Blog Post
    ... to reduce false positive rates and control for large numbers of comparisons. The Bonferroni does this...arranging all calculated p values from smallest to largest and ranking them (1 being the smallest value). ...calculates the cut off for significance by finding the largest p value where its rank divided by the total number...
Showing: 361 - 380 of 497 results