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Addgene

Enter a sequence to perform a BLAST-based search of the Addgene plasmid sequence database.

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In Category

We narrowed to 399 results for: MUT

Showing: 381 - 399 of 399 results

  1. Retrovirus Plasmids

    Type
    Collection
    ... can lead to oncogenesis (termed insertional mutagenesis). Read our γ-Retrovirus Guide for more information...

  3. Distribution to Industry

    Type
    Collection
    ...Library name Type PI Description HR700_TP53 Exon Mutation Libraries CRISPR Thorsten Stiewe Use these donor...

  4. Antibody Plasmid Collection

    Type
    Collection
    ...isotype-switched chimeric antibodies, and Fc-silent mutants. Functional diversification of hybridoma-produced...

  5. mTOR Pathway

    Type
    Collection
    ...multiple familial cancers are caused by inactivating mutations in negative regulators of mTORC1. The hyperactivation...

  6. TALEN Guide

    Type
    Collection
    ...in a C. elegans lab and have been struggling to mutate a specific gene or your anxiously investigating...

  7. Viral Production

    Type
    Collection
    ...for viral production are propagated in the endA -mutated NEB Stable strain of E. coli . In addition, plasmids...

  8. Lentivirus Plasmids

    Type
    Collection
    ... genome, it has the potential for insertional mutagensis. The 2nd and 3rd generation lentiviral systems...

  10. Adeno-associated virus (AAV) Guide

    Type
    Guide
    ... create and test capsid libraries with random mutations or insertions in the Cap region. Several methods...immune response, and the low risk of insertional mutagenesis. Several AAV-based gene therapies have been approved...chromosome, which reduces the risk of insertional mutagenesis. However, random integration events can occur...host organism, leading to disease. Insertional mutagenesis Random insertion of DNA elements into the genome...material into cells. Replication-competent rAAV Mutated rAAV vector that has the ability to replicate and...

  11. Optogenetics AAV Preps

    Type
    Collection
    ...Excitatory Wild-type ChR2 ChR2/H134R soCoChR ChR2/other mutants Chronos, Chrimson, ChRmine, ChroME, ChETA, C1V1...

  12. Lentiviral Vector Guide

    Type
    Guide
    ...harnessed for stable delivery of various genes, mutations, or treatments into cells, and has been widely... the laboratory, and many have been removed or mutated for increased safety. Figure 1: Wild-type lentivirus...biological processes by surveying a pool of genetic mutants for various phenotypes. These screens involve hundreds...used to create transgenic mice with heritable mutations or transgene expression. Popular uses include ...

  14. Bacterial Expression Systems

    Type
    Collection
    ... delete genes from or introduce new genes and mutations to the bacterial genome itself. Manipulating the...

  15. Plasmids for Stem Cell Research

    Type
    Collection
    ... cell division, all of which lower the risk of mutation and minimize tumorigenicity, an inherent disadvantage...

  16. Chemogenetics Guide

    Type
    Guide
    ...? blog! Studies of GPCRs led to development of mutated receptors that while unresponsive to endogenous...PSEMs). PSAM domains were first named for the mutations that allowed them to respond to their cognate ...anti-smoking drug varenicline. This PSAM carries mutations at L131G, Q139L, and Y217F and is termed PSAM4...

  17. Adenovirus Guide

    Type
    Guide
    ...highly reduces the potential for insertional mutagenesis and the risk of oncogenesis. However, random ... signals of infection or damage. Insertional mutagenesis Random insertion of DNA elements into the genome... cells. Replication-competent adenovirus (RCA) Mutated adenoviral vector that has the ability to replicate...

  18. Gamma-Retroviral Vector Guide

    Type
    Guide
    ...harnessed for stable delivery of various genes, mutations, or treatments into cells, and has been widely...

  19. Molecular Biology Reference

    Type
    Guide
    ... gene function as well as identify changes or mutations that may cause certain diseases. Sequencing DNA...
Showing: 381 - 399 of 399 results