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We narrowed to 12 results for: David Sabatini

Showing: 1 - 12 of 12 results

  1. Lentiviral CRISPR Libraries Enable Genome-Scale, Knockout Screening

    Type
    Blog Post
    ...by MIT's Tim Wang and colleagues, including David Sabatini and Eric Lander, comprise 73,171 guide RNAs...systematic genetic screens in mammalian cells,” David Sabatini, a senior author of one of the Science papers...genes and it includes more guides per gene. The Sabatini/Lander library uses sequential infection first... Using the CRISPR/Cas9 System. Wang T, Wei JJ, Sabatini DM, Lander ES. Science. 2013 Dec 12. (PubMed)....

  2. Modulate the Activity of 17 Signaling Pathways with One Kit!

    Type
    Blog Post
    ...collaboration with “cloning guru” Kathleen Ottina and David Sabatini at the Whitehead Institute and MIT, started...differentiation.” https://www.addgene.org/kits/sabatini-wood-cancer-pathway-orfs/ Finding signaling pathways...

  3. 15 Years of Addgene: The Top 15 Plasmids

    Type
    Blog Post
    ...pMDLg/pRPE. scramble shRNA - This plasmid from David Sabatini’s lab is a 3rd generation lentiviral vector ...pLKO.1 - TRC cloning vector - This vector from the David Root lab is a 3rd generation lentiviral transfer...

  4. mTOR Pathway

    Type
    Collection
    ...for this page was generated with the help of David Sabatini . mTOR Pathway Color is used for clarity and...for this page was generated with the help of David Sabatini . Return to top mTOR Pathway - Gene List Click...ORF Kit (Sabatini & Wood) Tackling Cancers’ Drug Resistance with a New Screening Kit (from David Sabatini...signaling in growth control and disease. Laplante M, Sabatini DM. Cell. 2012 Apr 13;149(2):274-93. doi: 10.1016...

  5. Cancer Research Plasmids and Resources

    Type
    Collection
    ...’ Drug Resistance with a New Screening Kit (David Sabatini & Kris Wood) National Cancer Institute (NCI...Cancer Pathways ORFs Kit : Set of vectors from the Sabatini & Wood Labs containing cDNAs for studying oncogenic...

  6. Tetracycline Inducible Expression

    Type
    Collection
    ...another gene of interest. tTA-Advanced Tight TRE David Sabatini 19407 pTREtight2 Empty backbone for Tet-controlled...and puromycin selection rtTA-Advanced Tight TRE David Root 100521 pCW57.1-MAT2A Lentiviral Tet-Off vector...constitutively expressed by EF1a promoter Tet-On 3G rtTA David Vereide 120309 pAAV-FAH-rtTA3G AAV vector to express...

  7. CRISPR References and Information

    Type
    Collection
    ...the Broad GPP and developed by the John Doench , David Root , and Hyongbum Kim Labs. E-CRISPR (Link opens...Cas9 ; p201N Cas9 ; pUC gRNA Shuttle PDF, 500 KB Sabatini and Lander gRNA cloning into pLX-sgRNA pLX-sgRNA...

  8. Neurodegeneration Plasmid Collection

    Type
    Collection
    ...hTLS.pBSKS(+) FUS T7 ALS David Ron 21828 TLS 2: hTLS.pCDNA1 FUS CMV ALS David Ron 21829 TLS 3: TLS.pRSET.C...TLS.pRSET.C FUS His T7 ALS David Ron 21830 TLS 4: hTLS-CHOP.pBSKS(+) FUS T7 ALS David Ron 21831 TLS 5:hTLS-...Foundation MJFF 38243 pLJM60-Tia1 TIA1 Flag CMV ALS David Sabatini 38248 pMXs-IP HA-Parkin PRKN HA Parkinson's...GFP CMV Huntington's David Rubinsztein 40262 pEGFP-Q74 HTT GFP CMV Huntington's David Rubinsztein 40263 ...CMV Huntington's David Rubinsztein 40264 pHM6-Q74 HTT His, HA CMV Huntington's David Rubinsztein 40364...Parkinson's David Rubinsztein 40823 EGFP-alphasynuclein-A53T SNCA GFP CMV Parkinson's David Rubinsztein...Parkinson's David Rubinsztein 40825 pHM6-alphasynuclein-A53T SNCA His, HA CMV Parkinson's David Rubinsztein...

  9. CRISPR History and Development for Genome Engineering

    Type
    Collection
    ...351(6268):84-8. PMID: 26628643 Wang T, Wei JJ, Sabatini DM, Lander ES. 2014. Genetic Screens in Human ...MF, Hidalgo-Reyes Y, Wiedenheft B, Maxwell KL, Davidson AR. 2015. Multiple mechanisms for CRISPR-Cas inhibition...26416740 Bondy-Denomy J, Pawluk A, Maxwell KL, Davidson AR. 2013. Bacteriophage genes that inactivate ..., Edraki A, Shah M, Sontheimer EJ, Maxwell KL, Davidson AR. 2016. Naturally occurring off-switches for...

  10. Optogenetics Guide

    Type
    Guide
    ...:159-72. PMID 22179551 Saunders A, Johnson CA, Sabatini BL 2012. Novel recombinant adeno-associated viruses...21363959 Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, O'Shea DJ, Sohal VS, Goshen I, Finkelstein...

  11. CRISPR Guide

    Type
    Guide
    ...pecific I ntegrase G ene E diting), developed by the David Liu lab , pairs prime editing with a large serine... 661–667. PMID: 25961408 Wang, T., Wei, J. J., Sabatini, D. M., & Lander, E. S. (2014). Genetic screens...Bondy-Denomy, J., Pawluk, A., Maxwell, K. L., & Davidson, A. R. (2013). Bacteriophage genes that inactivate...Hidalgo-Reyes, Y., Wiedenheft, B., Maxwell, K. L., & Davidson, A. R. (2015). Multiple mechanisms for CRISPR–...Cofsky, J. C., Kranzusch, P. J., Sontheimer, E. J., Davidson, A. R., Maxwell, K. L., & Doudna, J. A. (2017)...Shah, M., Sontheimer, E. J., Maxwell, K. L., & Davidson, A. R. (2016). Naturally occurring Off-Switches...Wiegand, D. J., Ter-Ovanesyan, D., Braff, J. L., Davidsohn, N., Housden, B. E., Perrimon, N., Weiss, R., ...

  12. CRISPR Guide

    Type
    Collection
    ...pecific I ntegrase G ene E diting), developed by the David Liu lab , pairs prime editing with a large serine... 661–667. PMID: 25961408 Wang, T., Wei, J. J., Sabatini, D. M., & Lander, E. S. (2014). Genetic screens...Bondy-Denomy, J., Pawluk, A., Maxwell, K. L., & Davidson, A. R. (2013). Bacteriophage genes that inactivate...Hidalgo-Reyes, Y., Wiedenheft, B., Maxwell, K. L., & Davidson, A. R. (2015). Multiple mechanisms for CRISPR–...Cofsky, J. C., Kranzusch, P. J., Sontheimer, E. J., Davidson, A. R., Maxwell, K. L., & Doudna, J. A. (2017)...Shah, M., Sontheimer, E. J., Maxwell, K. L., & Davidson, A. R. (2016). Naturally occurring Off-Switches...Wiegand, D. J., Ter-Ovanesyan, D., Braff, J. L., Davidsohn, N., Housden, B. E., Perrimon, N., Weiss, R., ...
Showing: 1 - 12 of 12 results