...efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell...easily isolated from donors. Apart from fibroblasts, human keratinocytes from hair pluck, peripheral blood ...types have been successfully differentiated from human iPSCs. Below is a list of some of these cell types...transdifferentiation of glucagon-producing α-cells into insulin-producing β-like-cells [37, 38]. In 1987, Davis... Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell, 2007. 131(...Induced pluripotent stem cell lines derived from human somatic cells. Science, 2007. 318(5858): p. 1917... et al., Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive...

...methyltransferase INSR Insulin receptor INSRR Insulin receptor-related receptor IRS IRS1 IRS2 Insulin receptor substrate...the most common oncogene in human cancer, found in around 20-25% of all human cancers. Ras Pathway Plasmids...constitutively active Ras is the most common oncogene in human cancer. Cancer...

...diabetes mellitus. Recombinant human proteins that play a role in insulin regulation and diabetes will ...

...physiologically similar to humans than many other model organisms, they are often used to study human diseases. Diseases...counterpart in humans (Liu et al., 2017) . Thus yeast can be used to study the molecular basis of human diseases...They share about 70% of their genes with humans and 85% of human genes associated with a disease have a ...the globe. These organisms share many genes with humans, are easily maintained in the lab, and have short...Diseases in mice show many similar phenotypes to human diseases and have successfully helped researchers...system. The fly has also emerged as an important human disease model with potential for therapeutic drug... estimated that 75% of disease causing genes in humans have a functional homolog in the fly (Pandey and...

...Uhlen M. Large-scale affinity purification of human insulin-like growth factor I from culture medium of ...

...lineage-control network that differentiates human IPSCs into glucose-sensitive insulin-secreting beta-like cells." Nature...

...p53 is the most frequently mutated gene (>50%) in human cancer; most of these mutations are missense mutations...mutagens like radiation or viruses (e.g., HPV, the human papillomavirus). These mutations interfere with ...DNA-damage-inducible; alpha, beta, or gamma IGF-BP3 Insulin-like growth factor binding protein 3 KAI CD82 molecule.... Uncovering the role of p53 splice variants in human malignancy: a clinical perspective. Surget S, Khoury...45-53. PubMed PMID: 11780111 . p53 mutations in human cancers. Hollstein M, Sidransky D, Vogelstein B,...

...Mullineaux Insulin Sensor for Imaging Insulin Secretion A Ratiometric Sensor for Imaging Insulin Secretion...functionally distinct interneurons in mice, non-human primates and humans. Nat Neurosci. 2020 Dec;23(12):1629-1636...action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe. Nat Commun. 2018 Aug...pHluorin-mKate2, Tandem Fluorescent Protein-Tagged Human LC3 for the Monitoring of Mammalian Autophagy. PLoS...

... omega 1 - IGF1 insulin-like growth factor 1 (somatomedin C) IGF1A, IGFI IGF1R insulin-like growth factor... MGC4638 INS insulin ILPR, IRDN INS-IGF2 INS-IGF2 readthrough transcript - INSL3 insulin-like 3 (Leydig...MGC119819, RLF, RLNL INSL4 insulin-like 4 (placenta) EPIL, PLACENTIN INSL5 insulin-like 5 MGC126695, MGC126697...MGC126697, PRO182, UNQ156 INSL6 insulin-like 6 RIF1 INSR insulin receptor CD220, HHF5 JAG1 jagged 1 (Alagille... Plasmid Kits and Collections Human Kinase ORF Kit : 558 distinct human kinases and kinase-related protein...FLJ21044, HGPPS, HGPS, RBIG1, RIG1 RXFP3 relaxin/insulin-like family peptide receptor 3 GPCR135, MGC141998...IGFR, JTK13, MGC142170, MGC142172, MGC18216 IGF2 insulin-like growth factor 2 (somatomedin A) C11orf43, ...

...the human Estrogen Binding Domain (EBD) TDH3 Yeast van Leeuwen 64770 pSS146 Cre fused to the human Estrogen...Littman 24333 ins-cre_cryaa-Venus Cre-Venus fusion insulin Zebrafish Stainier 24593 AAV-pgk-Cre codon optimized...