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We narrowed to 729 results for: NSI

Showing: 291 - 300 of 729 results

  1. Running for Rare Disease, Running for FOP, Running for AJ

    Type
    Blog Post
    Published
    Sept. 15, 2016, 2:30 p.m.
    ...put on typical middle age weight and “exercise” consisted of taking walks in the mall. I took action, joined...patients. However, the R206H mutation makes ACVR1 responsive to members of the ubiquitous activin ligand family... to raising funds and awareness of FOP. Please consider running with us or making a donation via the link...

  2. The Stingy Scientist: How the Baby Gel Box Was Born

    Type
    Blog Post
    Published
    April 15, 2014, 3:11 p.m.
    ...labs. Disposable plastic materials are fairly inexpensive in this country and we are quick to throw out... gel on a large glass slide using only surface tension.  It's a bit tricky to pour the right amount so...plastic and solder this thing together.  One of the downsides—there was no cover so you had to be careful not...

  3. Antibodies 101: Chimeric Antibodies

    Type
    Blog Post
    Published
    April 25, 2023, 1:15 p.m.
    ...how Protein A and Protein B interact. You read extensive research on the two proteins and come up with ...antibody against Protein B. The antibodies are both extensively published, knockout validated, and work in your...with human antibody sequences.  Additional considerations Although isotype conversion is routinely used...

  4. Hot Plasmids - June 2020 - Barcoded CRISPR Library, Sparse Cell Labeling, Calcineurin Reporter, and DNA Staining Dye Alternative

    Type
    Blog Post
    Published
    June 2, 2020, 1:15 p.m.
    ...cells. Until now, tools for doing this were labor-intensive and required using manipulations such as injection...sites in the construct to different lengths, the density of cells that are labeled can be altered to dense...designed a calcineurin transcriptional reporter consisting of a quickly-degraded destabilized GFP variant...

  5. Fluorescent Biosensors for Measuring Autophagic Flux

    Type
    Blog Post
    Published
    Jan. 22, 2019, 2:41 p.m.
    ...a relatively pH-insensitive RFP variant, DsRed.T3, that’s connected to a pH-sensitive GFP variant, super...lysosome, and degradation of autophagic substrates inside the lysosome. Historically, methods for studying...

  6. HA Frankenbody, a New Imaging Tool to Visualize Single Molecules and Nascent Peptides

    Type
    Blog Post
    Published
    Oct. 10, 2019, 12:41 p.m.
    ...proteins in vivo. These probes however can be expensive to make, hard to deliver into living systems, ..., and often do not fold properly once inside cells.  Developing the HA frankenbody To combat the issues...found that the HA frankenbody is effective in sensitive cells such as living neurons, and can be fused...

  7. Identifying Sequence Elements with SnapGene's Feature Database

    Type
    Blog Post
    Published
    Dec. 21, 2017, 2:06 p.m.
    ...markers and replication origins, but there is extensive heterogeneity in the feature sequences due to ...control elements in commercial plasmids were inconsistent and sometimes clearly wrong. In an effort to...reliable feature annotations. Even with these extensive efforts, such an algorithm has limitations. For...

  8. Science Careers: Unruly Interests Feed Many Paths

    Type
    Blog Post
    Published
    Sept. 26, 2017, 12:12 p.m.
    ...at our graphics and design editors. How about condensing a week’s worth of the world’s scientific discoveries...like word choice, punctuation, and stylistic consistency. If you’ve ever doubted the importance of copy...in the science communications world, you might consider an internship or a short program to build skills...

  9. Hot Plasmids - January 2023

    Type
    Blog Post
    Published
    Jan. 31, 2023, 2:15 p.m.
    ...applications such as super resolution, electron, and expansion microscopy. hfYFP is not only brilliantly bright...than most FPs. The group also tested hfYFP in expansion microscopy as well as correlative light and electron...stable FP for your next microscopy experiment, consider hfYFP and LSSmGFP.     Fig. 4: hfYFP retains...
Showing: 291 - 300 of 729 results