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Showing: 61 - 80 of 214 results

  1. Bringing Sustainable Practices to the Lab: Recycling

    Type
    Blog Post
    Published
    Feb. 14, 2019, 2:35 p.m.
    ...environment. I recently attended the Go green! Innovative practices for laboratory waste symposium, sponsored... Bringing Sustainable Practices to the Lab: Innovations Bringing Sustainable Practices to the Lab: Easy...

  2. Comparing Cas9 to NgAgo: Can the Argonautes Best CRISPR?

    Type
    Blog Post
    Published
    June 9, 2016, 2:30 p.m.
    ...small capacity viral vectors such as AAV. Base removal RNA-guided CRISPR enzymes cause double-stranded...a natural context, it’s hypothesized that base removal helps prevent the invading genome from “recovering...

  3. Extracurricular Activities for a Strong Science Career Path

    Type
    Blog Post
    Published
    Jan. 21, 2014, 3:08 p.m.
    ...experiments are crucial in demonstrating the true innovation, impact and, in turn, the big picture of the ...committee is not convinced that your project is an innovative solution with a strong impact, or a journalist...

  4. Photosensitizer Induced Cell Ablation with FAP-TAP MG-2I-dL5**

    Type
    Blog Post
    Published
    Sept. 19, 2017, 1:20 p.m.
    ...PMC4445427. 3. Bulina, M. E., Chudakov, D. M., Britanova, O. V., Yanushevich, Y. G., Staroverov, D. B.,...Fluorescent Protein Guide Page Check out MiniSOG2 and SuperNova, two other photosensitizers used for cell ablation...

  5. A Deep Dive into BioBuilder

    Type
    Blog Post
    Published
    Oct. 11, 2017, 1:44 p.m.
    ...contributed by Mary Tamer from BioBuilder, an innovative nonprofit bringing the study of synthetic biology...state-of-the-art lab embedded in LabCentral’s community of innovators that opened in August 2017.  This flexible teaching...

  6. Kiran Musunuru on the Newest TALEN Genome-Editing System

    Type
    Blog Post
    Published
    Dec. 10, 2013, 3:13 p.m.
    ...Regenerative Biology is to understand the basis for cardiovascular and metabolic human diseases. They do that ... target a large number of genes involved in cardiovascular and metabolic diseases. We are knocking out...

  7. Antibodies 101: Fab Fragments

    Type
    Blog Post
    Published
    Sept. 5, 2024, 1:15 p.m.
    ... region and a variable region. The chains are covalently linked to one another by disulfide bonds between...are bivalent, so may have higher avidity than monovalent Fab’ or Fab fragments. Higher avidity means that...

  8. dTAG - You're it!

    Type
    Blog Post
    Published
    June 21, 2018, 2:06 p.m.
    ... we synthesize compounds that enable selective removal of proteins-of-interest from the proteome. Rather....harvard.edu), or Jay Bradner (james.bradner@novartis.com). Considerations when getting the dTAG system...

  9. Visualizing Protein Turnover In Situ

    Type
    Blog Post
    Published
    Jan. 16, 2018, 3:20 p.m.
    ...proteins can be detected using click-chemistry that covalently links the azido containing AHA to a fluorescent...Right now, she is a science instructor at The Innovation Institute in Boston. When Eugenia is not by the...

  10. Celebrating 15 Years of Scientific Sharing

    Type
    Blog Post
    Published
    Jan. 14, 2019, 2:08 p.m.
    ...one, is a sterling example of collaboration and innovation between legal and scientific fields.” Thanks ... every day for their dedication, flexibility, innovative thinking, and openness to team work.   Company...

  11. 5 Steps to Writing Grant Proposals for Grad Students

    Type
    Blog Post
    Published
    Feb. 11, 2014, 12:13 p.m.
    ...Research Strategy highlights i) the significance and innovation of the project and ii) how you, the expert, will...funding. Convince the readers why and how your innovation will address a variety of challenges and impact...

  12. CRISPR 101: Targeting Non-Coding RNAs with CRISPR/Cas9

    Type
    Blog Post
    Published
    Nov. 14, 2024, 2:15 p.m.
    ... can result in the retention of introns or the removal of exons. Disrupting promoter or transcription ...) deletion. (B) Mutations of splice sites. (C) Removal of an exon or a large genomic fragment. (D) Knock-in...

  14. Corralling and Cornering the Goldilocks Antibody

    Type
    Blog Post
    Published
    Aug. 9, 2022, 1:15 p.m.
    ...support from the Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative Cell Census...Atlas will foster collaboration, progress, and innovation by allowing scientists to find and utilize reliable...

  15. Cpf1 Update: Comparison to Cas9 and NgAgo

    Type
    Blog Post
    Published
    July 14, 2016, 2:30 p.m.
    ... B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der...plasmids from this publication at Addgene. 4. Makarova KS, Wolf YI, Alkhnbashi OS, Costa F, Shah SA, ...

  16. Academic vs. Industry Postdocs

    Type
    Blog Post
    Published
    Nov. 13, 2018, 1:22 p.m.
    ...postdoc positions, including AstraZeneca, Pfizer, Novartis, Biogen, Amgen, New England Biolabs, Regeneron...pre-approved project. Other companies, such as Novartis, have specific web sites for postdoc listings,...

  18. An Introduction to Adenovirus

    Type
    Blog Post
    Published
    Oct. 3, 2023, 1:15 p.m.
    ...likely for adenoviral vectors – namely due to the removal of certain adenoviral genes that apparently contribute...36996871. Tatsis, N., Fitzgerald, J. C., Reyes-Sandoval, A., Harris-McCoy, K. C., Hensley, S. E., Zhou...

  19. Getting to Know Expansion Microscopy

    Type
    Blog Post
    Published
    June 20, 2023, 1:15 p.m.
    ...have been found to help improve label density (Mikhaylova, et al. 2015).  Despite these limitations, ExM.... https://doi.org/10.1038/s41587-022-01546-1  Mikhaylova M, Cloin BMC, Finan K, et al (2015) Resolving...

  20. Plasmids 101: Secondary Nanobody Toolbox

    Type
    Blog Post
    Published
    Feb. 27, 2018, 2:04 p.m.
    ...incubation can be skipped by pre-binding to 1° Monovalent Monoclonal Only anti- rabbit and -mouse versions...Maleimide-labeling occurs when a maleimide group forms a covalent bond with a sulfhydryl group (–SH), such as that...
Showing: 61 - 80 of 214 results