We narrowed to 217 results for: OVA
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TypeBlog PostPublishedFeb. 14, 2019, 2:35 p.m....environment. I recently attended the Go green! Innovative practices for laboratory waste symposium, sponsored... Bringing Sustainable Practices to the Lab: Innovations Bringing Sustainable Practices to the Lab: Easy...
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Comparing Cas9 to NgAgo: Can the Argonautes Best CRISPR?
TypeBlog PostPublishedJune 9, 2016, 2:30 p.m....small capacity viral vectors such as AAV. Base removal RNA-guided CRISPR enzymes cause double-stranded...a natural context, it’s hypothesized that base removal helps prevent the invading genome from “recovering... -
Extracurricular Activities for a Strong Science Career Path
TypeBlog PostPublishedJan. 21, 2014, 3:08 p.m....experiments are crucial in demonstrating the true innovation, impact and, in turn, the big picture of the ...committee is not convinced that your project is an innovative solution with a strong impact, or a journalist... -
Photosensitizer Induced Cell Ablation with FAP-TAP MG-2I-dL5**
TypeBlog PostPublishedSept. 19, 2017, 1:20 p.m....PMC4445427. 3. Bulina, M. E., Chudakov, D. M., Britanova, O. V., Yanushevich, Y. G., Staroverov, D. B.,...Fluorescent Protein Guide Page Check out MiniSOG2 and SuperNova, two other photosensitizers used for cell ablation... -
A Deep Dive into BioBuilder
TypeBlog PostPublishedOct. 11, 2017, 1:44 p.m....contributed by Mary Tamer from BioBuilder, an innovative nonprofit bringing the study of synthetic biology...state-of-the-art lab embedded in LabCentral’s community of innovators that opened in August 2017. This flexible teaching... -
Kiran Musunuru on the Newest TALEN Genome-Editing System
TypeBlog PostPublishedDec. 10, 2013, 3:13 p.m....Regenerative Biology is to understand the basis for cardiovascular and metabolic human diseases. They do that ... target a large number of genes involved in cardiovascular and metabolic diseases. We are knocking out... -
Antibodies 101: Fab Fragments
TypeBlog PostPublishedSept. 5, 2024, 1:15 p.m.... region and a variable region. The chains are covalently linked to one another by disulfide bonds between...are bivalent, so may have higher avidity than monovalent Fab’ or Fab fragments. Higher avidity means that... -
Visualizing Protein Turnover In Situ
TypeBlog PostPublishedJan. 16, 2018, 3:20 p.m....proteins can be detected using click-chemistry that covalently links the azido containing AHA to a fluorescent...Right now, she is a science instructor at The Innovation Institute in Boston. When Eugenia is not by the... -
Celebrating 15 Years of Scientific Sharing
TypeBlog PostPublishedJan. 14, 2019, 2:08 p.m....one, is a sterling example of collaboration and innovation between legal and scientific fields.” Thanks ... every day for their dedication, flexibility, innovative thinking, and openness to team work. Company... -
dTAG - You're it!
TypeBlog PostPublishedJune 21, 2018, 2:06 p.m.... we synthesize compounds that enable selective removal of proteins-of-interest from the proteome. Rather....harvard.edu), or Jay Bradner (james.bradner@novartis.com). Considerations when getting the dTAG system... -
5 Steps to Writing Grant Proposals for Grad Students
TypeBlog PostPublishedFeb. 11, 2014, 12:13 p.m....Research Strategy highlights i) the significance and innovation of the project and ii) how you, the expert, will...funding. Convince the readers why and how your innovation will address a variety of challenges and impact... -
CRISPR 101: Targeting Non-Coding RNAs with CRISPR/Cas9
TypeBlog PostPublishedNov. 14, 2024, 2:15 p.m.... can result in the retention of introns or the removal of exons. Disrupting promoter or transcription ...) deletion. (B) Mutations of splice sites. (C) Removal of an exon or a large genomic fragment. (D) Knock-in... -
Corralling and Cornering the Goldilocks Antibody
TypeBlog PostPublishedAug. 9, 2022, 1:15 p.m....support from the Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative Cell Census...Atlas will foster collaboration, progress, and innovation by allowing scientists to find and utilize reliable... -
BeHeard Award 2018: Diseases of Glycosylation, Arginine Mutagenesis, & Neural Development
TypeBlog PostPublishedJune 26, 2018, 1:33 p.m....Assistant Professor at the Faculty of Sciences of NOVA University in Lisbon, Portugal. She leads the Glycoimmunology...Given its unique molecular biology and previous approval by the FDA, GdnHCl could, in principle, provide... -
Cpf1 Update: Comparison to Cas9 and NgAgo
TypeBlog PostPublishedJuly 14, 2016, 2:30 p.m.... B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der...plasmids from this publication at Addgene. 4. Makarova KS, Wolf YI, Alkhnbashi OS, Costa F, Shah SA, ... -
Academic vs. Industry Postdocs
TypeBlog PostPublishedNov. 13, 2018, 1:22 p.m....postdoc positions, including AstraZeneca, Pfizer, Novartis, Biogen, Amgen, New England Biolabs, Regeneron...pre-approved project. Other companies, such as Novartis, have specific web sites for postdoc listings,... -
When is a Monomer not a Monomer? The Top Three Ways Your Favorite Fluorescent Protein Oligomerizes in Cells
TypeBlog PostPublishedApril 19, 2016, 2:30 p.m....remain unaware that EGFP/GFP is prone to forming noncovalent dimers. This property of EGFP can lead to significant...EGFP/GFP has a real nontrivial propensity to noncovalently dimerize. That means that your POI fused to ... -
Plasmids 101: Secondary Nanobody Toolbox
TypeBlog PostPublishedFeb. 27, 2018, 2:04 p.m....incubation can be skipped by pre-binding to 1° Monovalent Monoclonal Only anti- rabbit and -mouse versions...Maleimide-labeling occurs when a maleimide group forms a covalent bond with a sulfhydryl group (–SH), such as that... -
Getting to Know Expansion Microscopy
TypeBlog PostPublishedJune 20, 2023, 1:15 p.m....have been found to help improve label density (Mikhaylova, et al. 2015). Despite these limitations, ExM.... https://doi.org/10.1038/s41587-022-01546-1 Mikhaylova M, Cloin BMC, Finan K, et al (2015) Resolving... -
An Introduction to Adenovirus
TypeBlog PostPublishedOct. 3, 2023, 1:15 p.m....likely for adenoviral vectors – namely due to the removal of certain adenoviral genes that apparently contribute...36996871. Tatsis, N., Fitzgerald, J. C., Reyes-Sandoval, A., Harris-McCoy, K. C., Hensley, S. E., Zhou...