Chemogenetics Guide
Type
Guide
...Figure 2. PSAM4-based LGICs, their effect, and outcome in neurons. Please see the text or table 2 for details... Reference Rq(R165L) Human M3 muscarinic Arrestin-2/-3 CNO* Increase Arrestin translocation Arrestin signalling...hM1Dq hM5Dq Human M3 muscarinic G αq CNO* Increase Ca 2+ Neuronal burst firing Armbruster et al, 2007 rM3D... details. Table 2. Descriptions of PSAMs and their activity in neurons PSAM Ion Pore Domain Ligand(s) ...Forbes SL, Liggett SB (2001). Modification of the beta 2-adrenergic receptor to engineer a receptor-effector...Chem Neurosci 6:476–484. PMID: 25587888 Coward P, Wada HG, Falk MS, Chan SD, Meng F, et al (1998). Controlling...451–460. PMID: 15765260 Farrell MS, Pei Y, Wan Y, Yadav PN, Daigle TL, Urban DJ, Lee H-M, Sciaky N, Simmons...