lenti SYN-FLAG-dCas9-VPR Citations (11)
Originally described in: A Neuron-Optimized CRISPR/dCas9 Activation System for Robust and Specific Gene Regulation.Savell KE, Bach SV, Zipperly ME, Revanna JS, Goska NA, Tuscher JJ, Duke CG, Sultan FA, Burke JN, Williams D, Ianov L, Day JJ eNeuro. 2019 Mar 7;6(1). pii: eN-MNT-0495-18. doi: 10.1523/ENEURO.0495-18.2019. eCollection 2019 Jan-Feb. PubMed Journal
Articles Citing lenti SYN-FLAG-dCas9-VPR
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Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems.
Carullo NVN, Phillips Iii RA, Simon RC, Soto SAR, Hinds JE, Salisbury AJ, Revanna JS, Bunner KD, Ianov L, Sultan FA, Savell KE, Gersbach CA, Day JJ.
Nucleic Acids Res. 2020 Aug 18. pii: 5893972. doi: 10.1093/nar/gkaa671.
PubMed
Associated Plasmids |
Delivering progranulin to neuronal lysosomes protects against excitotoxicity.
Davis SE, Roth JR, Aljabi Q, Hakim AR, Savell KE, Day JJ, Arrant AE.
J Biol Chem. 2021 Sep;297(3):100993. doi: 10.1016/j.jbc.2021.100993. Epub 2021 Jul 21.
PubMed
Associated Plasmids |
A Cre-dependent CRISPR/dCas9 system for gene expression regulation in neurons.
Carullo NVN, Hinds JE, Revanna JS, Tuscher JJ, Bauman AJ, Day JJ.
eNeuro. 2021 Jul 26. pii: ENEURO.0188-21.2021. doi: 10.1523/ENEURO.0188-21.2021.
PubMed
Associated Plasmids |
An Improved CRISPR/dCas9 Interference Tool for Neuronal Gene Suppression.
Duke CG, Bach SV, Revanna JS, Sultan FA, Southern NT, Davis MN, Carullo NVN, Bauman AJ, Phillips RA 3rd, Day JJ.
Front Genome Ed. 2020 Sep 15;2:9. doi: 10.3389/fgeed.2020.00009. eCollection 2020.
PubMed
Associated Plasmids |
| Controlling hypothalamic DNA methylation at the Pomc promoter does not regulate weight gain during the development of obesity. McFadden T, Gaito N, Carucci I, Fletchall E, Farrell K, Jarome TJ. PLoS One. 2023 Apr 10;18(4):e0284286. doi: 10.1371/journal.pone.0284286. eCollection 2023. PubMed |
| Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length. Walker CK, Greathouse KM, Tuscher JJ, Dammer EB, Weber AJ, Liu E, Curtis KA, Boros BD, Freeman CD, Seo JV, Ramdas R, Hurst C, Duong DM, Gearing M, Murchison CF, Day JJ, Seyfried NT, Herskowitz JH. J Neurosci. 2023 May 17;43(20):3764-3785. doi: 10.1523/JNEUROSCI.2102-22.2023. Epub 2023 Apr 13. PubMed |
| Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice. Reynolds LM, Hernandez G, MacGowan D, Popescu C, Nouel D, Cuesta S, Burke S, Savell KE, Zhao J, Restrepo-Lozano JM, Giroux M, Israel S, Orsini T, He S, Wodzinski M, Avramescu RG, Pokinko M, Epelbaum JG, Niu Z, Pantoja-Urban AH, Trudeau LE, Kolb B, Day JJ, Flores C. Nat Commun. 2023 Jul 7;14(1):4035. doi: 10.1038/s41467-023-39665-1. PubMed |
| Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons. Bach SV, Bauman AJ, Hosein D, Tuscher JJ, Ianov L, Greathouse KM, Henderson BW, Herskowitz JH, Martinowich K, Day JJ. Hippocampus. 2024 May;34(5):218-229. doi: 10.1002/hipo.23600. Epub 2024 Feb 16. PubMed |
| Amphetamine in Adolescence Induces a Sex-Specific Mesolimbic Dopamine Phenotype in the Adult Prefrontal Cortex. Hernandez G, Zhao J, Niu Z, MacGowan D, Capolicchio T, Song A, Gul S, Moiz A, Herrera I, Day JJ, Flores C. bioRxiv [Preprint]. 2025 Mar 2:2025.02.26.640363. doi: 10.1101/2025.02.26.640363. PubMed |
MicroRNA mechanisms instructing Purkinje cell specification.
Zolboot N, Xiao Y, Du JX, Ghanem MM, Choi SY, Junn MJ, Zampa F, Huang Z, MacRae IJ, Lippi G.
Neuron. 2025 Apr 1:S0896-6273(25)00181-3. doi: 10.1016/j.neuron.2025.03.009.
PubMed
Associated Plasmids |
| Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage. Loth MK, Mesch KT, Herrera-Garcia C, Brusman LE, Donaldson ZR. Front Genome Ed. 2025 May 30;7:1602983. doi: 10.3389/fgeed.2025.1602983. eCollection 2025. PubMed |
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