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pAAV-hSyn-hChR2(H134R)-EYFP Citations (60)

Originally described in: hChR2 plasmids

Articles Citing pAAV-hSyn-hChR2(H134R)-EYFP

Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain. Aschauer DF, Kreuz S, Rumpel S. PLoS One. 2013 Sep 27;8(9):e76310. doi: 10.1371/journal.pone.0076310. eCollection 2013. PubMed
Optogenetics reveal delayed afferent synaptogenesis on grafted human-induced pluripotent stem cell-derived neural progenitors. Avaliani N, Sorensen AT, Ledri M, Bengzon J, Koch P, Brustle O, Deisseroth K, Andersson M, Kokaia M. Stem Cells. 2014 Dec;32(12):3088-98. doi: 10.1002/stem.1823. PubMed
Reward-timing-dependent bidirectional modulation of cortical microcircuits during optical single-neuron operant conditioning. Hira R, Ohkubo F, Masamizu Y, Ohkura M, Nakai J, Okada T, Matsuzaki M. Nat Commun. 2014 Nov 24;5:5551. doi: 10.1038/ncomms6551. PubMed
The calcium sensor synaptotagmin 7 is required for synaptic facilitation. Jackman SL, Turecek J, Belinsky JE, Regehr WG. Nature. 2016 Jan 7;529(7584):88-91. doi: 10.1038/nature16507. PubMed
Cellular resolution circuit mapping with temporal-focused excitation of soma-targeted channelrhodopsin. Baker CA, Elyada YM, Parra A, Bolton MM. Elife. 2016 Aug 15;5. pii: e14193. doi: 10.7554/eLife.14193. PubMed

Associated Plasmids

Genetic code expansion in the mouse brain. Ernst RJ, Krogager TP, Maywood ES, Zanchi R, Beranek V, Elliott TS, Barry NP, Hastings MH, Chin JW. Nat Chem Biol. 2016 Oct;12(10):776-8. doi: 10.1038/nchembio.2160. Epub 2016 Aug 29. PubMed
Intracortical Network Effects Preserve Thalamocortical Input Efficacy in a Cortex Without Layers. Guy J, Sachkova A, Mock M, Witte M, Wagener RJ, Staiger JF. Cereb Cortex. 2016 Sep 12. PubMed
Generation and validation of novel adeno-associated viral vectors for the analysis of Ca(2+) homeostasis in motor neurons. Norante RP, Massimino ML, Lorenzon P, De Mario A, Peggion C, Vicario M, Albiero M, Sorgato MC, Lopreiato R, Bertoli A. Sci Rep. 2017 Jul 26;7(1):6521. doi: 10.1038/s41598-017-06919-0. PubMed
Long-term expression of melanopsin and channelrhodopsin causes no gross alterations in the dystrophic dog retina. Ameline B, Tshilenge KT, Weber M, Biget M, Libeau L, Caplette R, Mendes-Madeira A, Provost N, Guihal C, Picaud S, Moullier P, Pichard V, Cronin T, Isiegas C. Gene Ther. 2017 Nov;24(11):735-741. doi: 10.1038/gt.2017.63. Epub 2017 Sep 7. PubMed
Labeling and identifying cell-specific proteomes in the mouse brain. Krogager TP, Ernst RJ, Elliott TS, Calo L, Beranek V, Ciabatti E, Spillantini MG, Tripodi M, Hastings MH, Chin JW. Nat Biotechnol. 2018 Feb;36(2):156-159. doi: 10.1038/nbt.4056. Epub 2017 Dec 18. PubMed
Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus. Avaliani N, Pfisterer U, Heuer A, Parmar M, Kokaia M, Andersson M. Stem Cells Int. 2017;2017:5718608. doi: 10.1155/2017/5718608. Epub 2017 Nov 26. PubMed
Task Division within the Prefrontal Cortex: Distinct Neuron Populations Selectively Control Different Aspects of Aggressive Behavior via the Hypothalamus. Biro L, Sipos E, Bruzsik B, Farkas I, Zelena D, Balazsfi D, Toth M, Haller J. J Neurosci. 2018 Apr 25;38(17):4065-4075. doi: 10.1523/JNEUROSCI.3234-17.2018. Epub 2018 Feb 27. PubMed
Anterior Thalamic Excitation and Feedforward Inhibition of Presubicular Neurons Projecting to Medial Entorhinal Cortex. Nassar M, Simonnet J, Huang LW, Mathon B, Cohen I, Bendels MHK, Beraneck M, Miles R, Fricker D. J Neurosci. 2018 Jul 11;38(28):6411-6425. doi: 10.1523/JNEUROSCI.0014-18.2018. Epub 2018 Jun 19. PubMed
Super-wide-field two-photon imaging with a micro-optical device moving in post-objective space. Terada SI, Kobayashi K, Ohkura M, Nakai J, Matsuzaki M. Nat Commun. 2018 Sep 3;9(1):3550. doi: 10.1038/s41467-018-06058-8. PubMed
Complex and spatially segregated auditory inputs of the mouse superior colliculus. Bednarova V, Grothe B, Myoga MH. J Physiol. 2018 Nov;596(21):5281-5298. doi: 10.1113/JP276370. Epub 2018 Oct 8. PubMed
Activation of the Rostral Intralaminar Thalamus Drives Reinforcement through Striatal Dopamine Release. Cover KK, Gyawali U, Kerkhoff WG, Patton MH, Mu C, White MG, Marquardt AE, Roberts BM, Cheer JF, Mathur BN. Cell Rep. 2019 Feb 5;26(6):1389-1398.e3. doi: 10.1016/j.celrep.2019.01.044. PubMed
Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue. Nagai J, Rajbhandari AK, Gangwani MR, Hachisuka A, Coppola G, Masmanidis SC, Fanselow MS, Khakh BS. Cell. 2019 May 16;177(5):1280-1292.e20. doi: 10.1016/j.cell.2019.03.019. Epub 2019 Apr 25. PubMed
Sensory perception drives food avoidance through excitatory basal forebrain circuits. Patel JM, Swanson J, Ung K, Herman A, Hanson E, Ortiz-Guzman J, Selever J, Tong Q, Arenkiel BR. Elife. 2019 May 10;8. pii: 44548. doi: 10.7554/eLife.44548. PubMed
A Specialized Neural Circuit Gates Social Vocalizations in the Mouse. Tschida K, Michael V, Takatoh J, Han BX, Zhao S, Sakurai K, Mooney R, Wang F. Neuron. 2019 Aug 7;103(3):459-472.e4. doi: 10.1016/j.neuron.2019.05.025. Epub 2019 Jun 13. PubMed
Cholinergic modulation of striatal nitric oxide-producing interneurons. Melendez-Zaidi AE, Lakshminarasimhah H, Surmeier DJ. Eur J Neurosci. 2019 Dec;50(11):3713-3731. doi: 10.1111/ejn.14528. Epub 2019 Aug 21. PubMed
Early-life stress impairs postnatal oligodendrogenesis and adult emotional behaviour through activity-dependent mechanisms. Teissier A, Le Magueresse C, Olusakin J, Andrade da Costa BLS, De Stasi AM, Bacci A, Imamura Kawasawa Y, Vaidya VA, Gaspar P. Mol Psychiatry. 2020 Jun;25(6):1159-1174. doi: 10.1038/s41380-019-0493-2. Epub 2019 Aug 22. PubMed
Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1. Robinson JE, Coughlin GM, Hori AM, Cho JR, Mackey ED, Turan Z, Patriarchi T, Tian L, Gradinaru V. Elife. 2019 Sep 23;8. pii: 48983. doi: 10.7554/eLife.48983. PubMed

Associated Plasmids

Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics. Bedbrook CN, Yang KK, Robinson JE, Mackey ED, Gradinaru V, Arnold FH. Nat Methods. 2019 Oct 14. pii: 10.1038/s41592-019-0583-8. doi: 10.1038/s41592-019-0583-8. PubMed

Associated Plasmids

micro-opioid receptor-mediated downregulation of midline thalamic pathways to basal and central amygdala. Goedecke L, Bengoetxea X, Blaesse P, Pape HC, Jungling K. Sci Rep. 2019 Nov 28;9(1):17837. doi: 10.1038/s41598-019-54128-8. PubMed
Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes. Tran NM, Shekhar K, Whitney IE, Jacobi A, Benhar I, Hong G, Yan W, Adiconis X, Arnold ME, Lee JM, Levin JZ, Lin D, Wang C, Lieber CM, Regev A, He Z, Sanes JR. Neuron. 2019 Dec 18;104(6):1039-1055.e12. doi: 10.1016/j.neuron.2019.11.006. Epub 2019 Nov 26. PubMed
Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice. Uezu A, Hisey E, Kobayashi Y, Gao Y, Bradshaw TW, Devlin P, Rodriguiz R, Tata PR, Soderling S. Elife. 2019 Dec 12;8. pii: 50712. doi: 10.7554/eLife.50712. PubMed
Pathway-, layer- and cell-type-specific thalamic input to mouse barrel cortex. Sermet BS, Truschow P, Feyerabend M, Mayrhofer JM, Oram TB, Yizhar O, Staiger JF, Petersen CC. Elife. 2019 Dec 20;8. pii: 52665. doi: 10.7554/eLife.52665. PubMed
Gut-seeded alpha-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice. Challis C, Hori A, Sampson TR, Yoo BB, Challis RC, Hamilton AM, Mazmanian SK, Volpicelli-Daley LA, Gradinaru V. Nat Neurosci. 2020 Mar;23(3):327-336. doi: 10.1038/s41593-020-0589-7. Epub 2020 Feb 17. PubMed
Layer-specific sensory processing impairment in the primary somatosensory cortex after motor cortex infarction. Fukui A, Osaki H, Ueta Y, Kobayashi K, Muragaki Y, Kawamata T, Miyata M. Sci Rep. 2020 Feb 28;10(1):3771. doi: 10.1038/s41598-020-60662-7. PubMed
Divergent Neural Pathways Emanating from the Lateral Parabrachial Nucleus Mediate Distinct Components of the Pain Response. Chiang MC, Nguyen EK, Canto-Bustos M, Papale AE, Oswald AM, Ross SE. Neuron. 2020 Jun 17;106(6):927-939.e5. doi: 10.1016/j.neuron.2020.03.014. Epub 2020 Apr 13. PubMed
Nonspecific Expression in Limited Excitatory Cell Populations in Interneuron-Targeting Cre-driver Lines Can Have Large Functional Effects. Muller-Komorowska D, Opitz T, Elzoheiry S, Schweizer M, Ambrad Giovannetti E, Beck H. Front Neural Circuits. 2020 Apr 27;14:16. doi: 10.3389/fncir.2020.00016. eCollection 2020. PubMed
Memory trace interference impairs recall in a mouse model of Alzheimer's disease. Poll S, Mittag M, Musacchio F, Justus LC, Giovannetti EA, Steffen J, Wagner J, Zohren L, Schoch S, Schmidt B, Jackson WS, Ehninger D, Fuhrmann M. Nat Neurosci. 2020 Aug;23(8):952-958. doi: 10.1038/s41593-020-0652-4. Epub 2020 Jun 8. PubMed
Deletion of NRXN1alpha impairs long-range and local connectivity in amygdala fear circuit. Asede D, Joseph A, Bolton MM. Transl Psychiatry. 2020 Jul 19;10(1):242. doi: 10.1038/s41398-020-00926-y. PubMed
High-fat food biases hypothalamic and mesolimbic expression of consummatory drives. Mazzone CM, Liang-Guallpa J, Li C, Wolcott NS, Boone MH, Southern M, Kobzar NP, Salgado IA, Reddy DM, Sun F, Zhang Y, Li Y, Cui G, Krashes MJ. Nat Neurosci. 2020 Oct;23(10):1253-1266. doi: 10.1038/s41593-020-0684-9. Epub 2020 Aug 3. PubMed
Human Stem Cell-Derived Neurons Repair Circuits and Restore Neural Function. Xiong M, Tao Y, Gao Q, Feng B, Yan W, Zhou Y, Kotsonis TA, Yuan T, You Z, Wu Z, Xi J, Haberman A, Graham J, Block J, Zhou W, Chen Y, Zhang SC. Cell Stem Cell. 2020 Sep 16. pii: S1934-5909(20)30410-0. doi: 10.1016/j.stem.2020.08.014. PubMed

Associated Plasmids

Relapse-Associated Transient Synaptic Potentiation Requires Integrin-Mediated Activation of Focal Adhesion Kinase and Cofilin in D1-Expressing Neurons. Garcia-Keller C, Scofield MD, Neuhofer D, Varanasi S, Reeves MT, Hughes B, Anderson E, Richie CT, Mejias-Aponte C, Pickel J, Hope BT, Harvey BK, Cowan CW, Kalivas PW. J Neurosci. 2020 Oct 28;40(44):8463-8477. doi: 10.1523/JNEUROSCI.2666-19.2020. Epub 2020 Oct 13. PubMed
The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment. Sanders SS, Hernandez LM, Soh H, Karnam S, Walikonis RS, Tzingounis AV, Thomas GM. Elife. 2020 Nov 13;9. pii: 56058. doi: 10.7554/eLife.56058. PubMed
Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17. Niu J, Sanders SS, Jeong HK, Holland SM, Sun Y, Collura KM, Hernandez LM, Huang H, Hayden MR, Smith GM, Hu Y, Jin Y, Thomas GM. Cell Rep. 2020 Nov 17;33(7):108365. doi: 10.1016/j.celrep.2020.108365. PubMed
Cell-type-specific recruitment of GABAergic interneurons in the primary somatosensory cortex by long-range inputs. Naskar S, Qi J, Pereira F, Gerfen CR, Lee S. Cell Rep. 2021 Feb 23;34(8):108774. doi: 10.1016/j.celrep.2021.108774. PubMed
An engineered channelrhodopsin optimized for axon terminal activation and circuit mapping. Hamada S, Nagase M, Yoshizawa T, Hagiwara A, Isomura Y, Watabe AM, Ohtsuka T. Commun Biol. 2021 Apr 12;4(1):461. doi: 10.1038/s42003-021-01977-7. PubMed
Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice. Liu C, Lee CY, Asher G, Cao L, Terakoshi Y, Cao P, Kobayakawa R, Kobayakawa K, Sakurai K, Liu Q. Nat Commun. 2021 May 11;12(1):2648. doi: 10.1038/s41467-021-22914-6. PubMed
Viral-mediated transduction of auditory neurons with opsins for optical and hybrid activation. Richardson RT, Thompson AC, Wise AK, Ajay EA, Gunewardene N, O'Leary SJ, Stoddart PR, Fallon JB. Sci Rep. 2021 May 27;11(1):11229. doi: 10.1038/s41598-021-90764-9. PubMed
Action potential-coupled Rho GTPase signaling drives presynaptic plasticity. O'Neil SD, Racz B, Brown WE, Gao Y, Soderblom EJ, Yasuda R, Soderling SH. Elife. 2021 Jul 16;10. pii: 63756. doi: 10.7554/eLife.63756. PubMed
Gated feedforward inhibition in the frontal cortex releases goal-directed action. Kim JH, Ma DH, Jung E, Choi I, Lee SH. Nat Neurosci. 2021 Oct;24(10):1452-1464. doi: 10.1038/s41593-021-00910-9. Epub 2021 Aug 19. PubMed
Bottom-up inputs are required for establishment of top-down connectivity onto cortical layer 1 neurogliaform cells. Ibrahim LA, Huang S, Fernandez-Otero M, Sherer M, Qiu Y, Vemuri S, Xu Q, Machold R, Pouchelon G, Rudy B, Fishell G. Neuron. 2021 Nov 3;109(21):3473-3485.e5. doi: 10.1016/j.neuron.2021.08.004. Epub 2021 Sep 2. PubMed
Short-Term Facilitation of Long-Range Corticocortical Synapses Revealed by Selective Optical Stimulation. Martinetti LE, Bonekamp KE, Autio DM, Kim HH, Crandall SR. Cereb Cortex. 2021 Sep 14. pii: 6369972. doi: 10.1093/cercor/bhab325. PubMed
Homologous organization of cerebellar pathways to sensory, motor, and associative forebrain. Pisano TJ, Dhanerawala ZM, Kislin M, Bakshinskaya D, Engel EA, Hansen EJ, Hoag AT, Lee J, de Oude NL, Venkataraju KU, Verpeut JL, Hoebeek FE, Richardson BD, Boele HJ, Wang SS. Cell Rep. 2021 Sep 21;36(12):109721. doi: 10.1016/j.celrep.2021.109721. PubMed
The mouse cortico-basal ganglia-thalamic network. Foster NN, Barry J, Korobkova L, Garcia L, Gao L, Becerra M, Sherafat Y, Peng B, Li X, Choi JH, Gou L, Zingg B, Azam S, Lo D, Khanjani N, Zhang B, Stanis J, Bowman I, Cotter K, Cao C, Yamashita S, Tugangui A, Li A, Jiang T, Jia X, Feng Z, Aquino S, Mun HS, Zhu M, Santarelli A, Benavidez NL, Song M, Dan G, Fayzullina M, Ustrell S, Boesen T, Johnson DL, Xu H, Bienkowski MS, Yang XW, Gong H, Levine MS, Wickersham I, Luo Q, Hahn JD, Lim BK, Zhang LI, Cepeda C, Hintiryan H, Dong HW. Nature. 2021 Oct;598(7879):188-194. doi: 10.1038/s41586-021-03993-3. Epub 2021 Oct 6. PubMed
Control of parallel hippocampal output pathways by amygdalar long-range inhibition. AlSubaie R, Wee RW, Ritoux A, Mishchanchuk K, Passlack J, Regester D, MacAskill AF. Elife. 2021 Nov 30;10. pii: 74758. doi: 10.7554/eLife.74758. PubMed
Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons. Joffe ME, Maksymetz J, Luschinger JR, Dogra S, Ferranti AS, Luessen DJ, Gallinger IM, Xiang Z, Branthwaite H, Melugin PR, Williford KM, Centanni SW, Shields BC, Lindsley CW, Calipari ES, Siciliano CA, Niswender CM, Tadross MR, Winder DG, Conn PJ. Neuron. 2022 Mar 16;110(6):1068-1083.e5. doi: 10.1016/j.neuron.2021.12.027. Epub 2022 Jan 18. PubMed
Median Raphe Nonserotonergic Neurons Modulate Hippocampal Theta Oscillations. Huang W, Ikemoto S, Wang DV. J Neurosci. 2022 Mar 9;42(10):1987-1998. doi: 10.1523/JNEUROSCI.1536-21.2022. Epub 2022 Jan 21. PubMed
A bottom-up reward pathway mediated by somatostatin neurons in the medial septum complex underlying appetitive learning. Shen L, Zhang GW, Tao C, Seo MB, Zhang NK, Huang JJ, Zhang LI, Tao HW. Nat Commun. 2022 Mar 7;13(1):1194. doi: 10.1038/s41467-022-28854-z. PubMed
Controlling absence seizures from the cerebellar nuclei via activation of the Gq signaling pathway. Schwitalla JC, Pakusch J, Mucher B, Bruckner A, Depke DA, Fenzl T, De Zeeuw CI, Kros L, Hoebeek FE, Mark MD. Cell Mol Life Sci. 2022 Mar 19;79(4):197. doi: 10.1007/s00018-022-04221-5. PubMed
Palmitoylation couples the kinases DLK and JNK3 to facilitate prodegenerative axon-to-soma signaling. Niu J, Holland SM, Ketschek A, Collura KM, Hesketh NL, Hayashi T, Gallo G, Thomas GM. Sci Signal. 2022 Mar 29;15(727):eabh2674. doi: 10.1126/scisignal.abh2674. Epub 2022 Mar 29. PubMed
Sparse genetically defined neurons refine the canonical role of periaqueductal gray columnar organization. La-Vu MQ, Sethi E, Maesta-Pereira S, Schuette PJ, Tobias BC, Reis FMCV, Wang W, Torossian A, Bishop A, Leonard SJ, Lin L, Cahill CM, Adhikari A. Elife. 2022 Jun 8;11. pii: 77115. doi: 10.7554/eLife.77115. PubMed
Synaptic location is a determinant of the detrimental effects of alpha-synuclein pathology to glutamatergic transmission in the basolateral amygdala. Chen L, Nagaraja C, Daniels S, Fisk ZA, Dvorak R, Meyerdirk L, Steiner JA, Escobar Galvis ML, Henderson MX, Rousseaux MWC, Brundin P, Chu HY. Elife. 2022 Jul 1;11. pii: 78055. doi: 10.7554/eLife.78055. PubMed
Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice. Takahashi A, Durand-de Cuttoli R, Flanigan ME, Hasegawa E, Tsunematsu T, Aleyasin H, Cherasse Y, Miya K, Okada T, Keino-Masu K, Mitsui K, Li L, Patel V, Blitzer RD, Lazarus M, Tanaka KF, Yamanaka A, Sakurai T, Ogawa S, Russo SJ. Nat Commun. 2022 Jul 21;13(1):4039. doi: 10.1038/s41467-022-31728-z. PubMed
Cingulate-motor circuits update rule representations for sequential choice decisions. Takeuchi D, Roy D, Muralidhar S, Kawai T, Bari A, Lovett C, Sullivan HA, Wickersham IR, Tonegawa S. Nat Commun. 2022 Aug 4;13(1):4545. doi: 10.1038/s41467-022-32142-1. PubMed
A stable sensory map emerges from a dynamic equilibrium of neurons with unstable tuning properties. Chambers AR, Aschauer DF, Eppler JB, Kaschube M, Rumpel S. Cereb Cortex. 2022 Nov 23:bhac445. doi: 10.1093/cercor/bhac445. PubMed
Rostral and caudal basolateral amygdala engage distinct circuits in the prelimbic and infralimbic prefrontal cortex. Manoocheri K, Carter AG. Elife. 2022 Dec 7;11:e82688. doi: 10.7554/eLife.82688. PubMed

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