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pLenti-puro Citations (71)

Originally described in: ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers.
Guan B, Wang TL, Shih IeM Cancer Res. 2011 Nov 1;71(21):6718-27. Epub 2011 Sep 7.
PubMed Journal

Articles Citing pLenti-puro

CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer. Zauri M, Berridge G, Thezenas ML, Pugh KM, Goldin R, Kessler BM, Kriaucionis S. Nature. 2015 Aug 6;524(7563):114-8. doi: 10.1038/nature14948. Epub 2015 Jul 22. PubMed
Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Sakamaki JI, Wilkinson S, Hahn M, Tasdemir N, O'Prey J, Clark W, Hedley A, Nixon C, Long JS, New M, Van Acker T, Tooze SA, Lowe SW, Dikic I, Ryan KM. Mol Cell. 2017 May 18;66(4):517-532.e9. doi: 10.1016/j.molcel.2017.04.027. PubMed
Interleukin-like EMT inducer regulates partial phenotype switching in MITF-low melanoma cell lines. Noguchi K, Dalton AC, Howley BV, McCall BJ, Yoshida A, Diehl JA, Howe PH. PLoS One. 2017 May 17;12(5):e0177830. doi: 10.1371/journal.pone.0177830. eCollection 2017. PubMed
SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth. Tamiya H, Kim H, Klymenko O, Kim H, Feng Y, Zhang T, Han JY, Murao A, Snipas SJ, Jilaveanu L, Brown K, Kluger H, Zhang H, Iwai K, Ronai ZA. J Clin Invest. 2018 Jan 2;128(1):517-530. doi: 10.1172/JCI95410. Epub 2017 Dec 11. PubMed
Analysis of transcriptional activity by the Myt1 and Myt1l transcription factors. Manukyan A, Kowalczyk I, Melhuish TA, Lemiesz A, Wotton D. J Cell Biochem. 2018 Jun;119(6):4644-4655. doi: 10.1002/jcb.26636. Epub 2018 Mar 9. PubMed
CD38 produces nicotinic acid adenosine dinucleotide phosphate in the lysosome. Fang C, Li T, Li Y, Xu GJ, Deng QW, Chen YJ, Hou YN, Lee HC, Zhao YJ. J Biol Chem. 2018 May 25;293(21):8151-8160. doi: 10.1074/jbc.RA118.002113. Epub 2018 Apr 9. PubMed
MicroRNA miR-509 Regulates ERK1/2, the Vimentin Network, and Focal Adhesions by Targeting Plk1. Liao G, Wang R, Rezey AC, Gerlach BD, Tang DD. Sci Rep. 2018 Aug 22;8(1):12635. doi: 10.1038/s41598-018-30895-8. PubMed
Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition. Jia D, Augert A, Kim DW, Eastwood E, Wu N, Ibrahim AH, Kim KB, Dunn CT, Pillai SPS, Gazdar AF, Bolouri H, Park KS, MacPherson D. Cancer Discov. 2018 Nov;8(11):1422-1437. doi: 10.1158/2159-8290.CD-18-0385. Epub 2018 Sep 4. PubMed
Misoprostol regulates Bnip3 repression and alternative splicing to control cellular calcium homeostasis during hypoxic stress. Field JT, Martens MD, Mughal W, Hai Y, Chapman D, Hatch GM, Ivanco TL, Diehl-Jones W, Gordon JW. Cell Death Discov. 2018 Sep 21;4:37. doi: 10.1038/s41420-018-0104-z. eCollection 2018. PubMed

Associated Plasmids

Myt1 and Myt1l transcription factors limit proliferation in GBM cells by repressing YAP1 expression. Melhuish TA, Kowalczyk I, Manukyan A, Zhang Y, Shah A, Abounader R, Wotton D. Biochim Biophys Acta Gene Regul Mech. 2018 Nov;1861(11):983-995. doi: 10.1016/j.bbagrm.2018.10.005. Epub 2018 Oct 10. PubMed
MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis. Kalkat M, Resetca D, Lourenco C, Chan PK, Wei Y, Shiah YJ, Vitkin N, Tong Y, Sunnerhagen M, Done SJ, Boutros PC, Raught B, Penn LZ. Mol Cell. 2018 Dec 6;72(5):836-848.e7. doi: 10.1016/j.molcel.2018.09.031. Epub 2018 Nov 8. PubMed
Fatty-acid binding protein 5 modulates the SAR1 GTPase cycle and enhances budding of large COPII cargoes. Melville D, Gorur A, Schekman R. Mol Biol Cell. 2019 Feb 1;30(3):387-399. doi: 10.1091/mbc.E18-09-0548. Epub 2018 Nov 28. PubMed
Sensitive ADAR editing reporter in cancer cells enables high-throughput screening of small molecule libraries. Fritzell K, Xu LD, Otrocka M, Andreasson C, Ohman M. Nucleic Acids Res. 2019 Feb 28;47(4):e22. doi: 10.1093/nar/gky1228. PubMed
Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition. Augert A, Eastwood E, Ibrahim AH, Wu N, Grunblatt E, Basom R, Liggitt D, Eaton KD, Martins R, Poirier JT, Rudin CM, Milletti F, Cheng WY, Mack F, MacPherson D. Sci Signal. 2019 Feb 5;12(567). pii: 12/567/eaau2922. doi: 10.1126/scisignal.aau2922. PubMed
Mutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6. Chryplewicz A, Tienda SM, Nahotko DA, Peters PN, Lengyel E, Eckert MA. Sci Rep. 2019 Mar 26;9(1):5195. doi: 10.1038/s41598-019-41352-5. PubMed
The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion. Fearnley GW, Young KA, Edgar JR, Antrobus R, Hay IM, Liang WC, Martinez-Martin N, Lin W, Deane JE, Sharpe HJ. Elife. 2019 Mar 29;8. pii: 44597. doi: 10.7554/eLife.44597. PubMed
Engineering proteins for allosteric control by light or ligands. Dagliyan O, Dokholyan NV, Hahn KM. Nat Protoc. 2019 Jun;14(6):1863-1883. doi: 10.1038/s41596-019-0165-3. Epub 2019 May 10. PubMed
mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux. Beaumatin F, O'Prey J, Barthet VJA, Zunino B, Parvy JP, Bachmann AM, O'Prey M, Kania E, Gonzalez PS, Macintosh R, Lao LY, Nixon C, Lopez J, Long JS, Tait SWG, Ryan KM. Mol Cell. 2019 Oct 3;76(1):163-176.e8. doi: 10.1016/j.molcel.2019.07.021. Epub 2019 Sep 3. PubMed
Generation of Knockout Human Primary Keratinocytes by CRISPR/Cas9. Grossi S, Fenini G, Hennig P, Di Filippo M, Beer HD. Methods Mol Biol. 2019 Sep 10. doi: 10.1007/7651_2019_262. PubMed
Carboxypeptidase A6 Promotes the Proliferation and Migration of Hepatocellular Carcinoma by Up-regulating AKT Signaling Pathway. Huang QB, Zhang HW, Liao ZB. Curr Med Sci. 2019 Oct;39(5):727-733. doi: 10.1007/s11596-019-2098-z. Epub 2019 Oct 14. PubMed
FABP5 coordinates lipid signaling that promotes prostate cancer metastasis. Carbonetti G, Wilpshaar T, Kroonen J, Studholme K, Converso C, d'Oelsnitz S, Kaczocha M. Sci Rep. 2019 Dec 12;9(1):18944. doi: 10.1038/s41598-019-55418-x. PubMed
A fluorescence activatable reporter of flavivirus NS2B-NS3 protease activity enables live imaging of infection in single cells and viral plaques. Arias-Arias JL, MacPherson DJ, Hill ME, Hardy JA, Mora-Rodriguez R. J Biol Chem. 2020 Jan 9. pii: RA119.011319. doi: 10.1074/jbc.RA119.011319. PubMed

Associated Plasmids

Silencing of long noncoding RNA LEF1-AS1 prevents the progression of hepatocellular carcinoma via the crosstalk with microRNA-136-5p/WNK1. Dong H, Jian P, Yu M, Wang L. J Cell Physiol. 2020 Oct;235(10):6548-6562. doi: 10.1002/jcp.29503. Epub 2020 Feb 18. PubMed
Targeting p63 Upregulation Abrogates Resistance to MAPK Inhibitors in Melanoma. Patel A, Garcia LF, Mannella V, Gammon L, Borg TM, Maffucci T, Scatolini M, Chiorino G, Vergani E, Rodolfo M, Maurichi A, Posch C, Matin RN, Harwood CA, Bergamaschi D. Cancer Res. 2020 Jun 15;80(12):2676-2688. doi: 10.1158/0008-5472.CAN-19-3230. Epub 2020 Apr 14. PubMed
TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the beta-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple. Zhang R, Li SW, Liu L, Yang J, Huang G, Sang Y. Oncogenesis. 2020 May 7;9(5):45. doi: 10.1038/s41389-020-0229-9. PubMed
Evaluation of an aldo-keto reductase gene signature with prognostic significance in colon cancer via activation of epithelial to mesenchymal transition and the p70S6K pathway. Demirkol Canli S, Seza EG, Sheraj I, Gomceli I, Turhan N, Carberry S, Prehn JHM, Gure AO, Banerjee S. Carcinogenesis. 2020 Jul 6. pii: 5867997. doi: 10.1093/carcin/bgaa072. PubMed
Proteosomal degradation of NSD2 by BRCA1 promotes leukemia cell differentiation. Park JW, Kang JY, Hahm JY, Kim HJ, Seo SB. Commun Biol. 2020 Aug 21;3(1):462. doi: 10.1038/s42003-020-01186-8. PubMed
Cell-cycle-gated feedback control mediates desensitization to interferon stimulation. Mudla A, Jiang Y, Arimoto KI, Xu B, Rajesh A, Ryan AP, Wang W, Daugherty MD, Zhang DE, Hao N. Elife. 2020 Sep 18;9. pii: 58825. doi: 10.7554/eLife.58825. PubMed
Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis. Gao W, Zhang Y, Luo H, Niu M, Zheng X, Hu W, Cui J, Xue X, Bo Y, Dai F, Lu Y, Yang D, Guo Y, Guo H, Li H, Zhang Y, Yang T, Li L, Zhang L, Hou R, Wen S, An C, Ma T, Jin L, Xu W, Wu Y. Cell Death Dis. 2020 Oct 26;11(10):919. doi: 10.1038/s41419-020-03104-6. PubMed
EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy. Bao Y, Oguz G, Lee WC, Lee PL, Ghosh K, Li J, Wang P, Lobie PE, Ehmsen S, Ditzel HJ, Wong A, Tan EY, Lee SC, Yu Q. Nat Commun. 2020 Nov 18;11(1):5878. doi: 10.1038/s41467-020-19704-x. PubMed
circPARD3 drives malignant progression and chemoresistance of laryngeal squamous cell carcinoma by inhibiting autophagy through the PRKCI-Akt-mTOR pathway. Gao W, Guo H, Niu M, Zheng X, Zhang Y, Xue X, Bo Y, Guan X, Li Z, Guo Y, He L, Zhang Y, Li L, Cao J, Wu Y. Mol Cancer. 2020 Nov 24;19(1):166. doi: 10.1186/s12943-020-01279-2. PubMed
ASH2L drives proliferation and sensitivity to bleomycin and other genotoxins in Hodgkin's lymphoma and testicular cancer cells. Constantin D, Widmann C. Cell Death Dis. 2020 Nov 30;11(11):1019. doi: 10.1038/s41419-020-03231-0. PubMed
A Role for Polo-Like Kinase 4 in Vascular Fibroblast Cell-Type Transition. Li J, Urabe G, Huang Y, Zhang M, Wang B, Marcho L, Shen H, Kent KC, Guo LW. JACC Basic Transl Sci. 2021 Mar 22;6(3):257-283. doi: 10.1016/j.jacbts.2020.12.015. eCollection 2021 Mar. PubMed
HnRNP F and hnRNP H1 regulate mRNA stability of amyloid precursor protein. Khan MI, Zhang J, Liu Q. Neuroreport. 2021 Jun 9;32(9):824-832. doi: 10.1097/WNR.0000000000001662. PubMed
TMEM97 ablation aggravates oxidant-induced retinal degeneration. Shen H, Li J, Heisler-Taylor T, Makin R, Yang H, Mavlyutov TA, Gelfand B, Cebulla CM, Guo LW. Cell Signal. 2021 Oct;86:110078. doi: 10.1016/j.cellsig.2021.110078. Epub 2021 Jul 7. PubMed
Negative Regulation of Erythroid Differentiation via the CBX8-TRIM28 Axis. Kim HJ, Park JW, Kang JY, Seo SB. Mol Cells. 2021 Jul 31;44(7):444-457. doi: 10.14348/molcells.2021.0012. PubMed
BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters. Kannangara AR, Poole DM, McEwan CM, Youngs JC, Weerasekara VK, Thornock AM, Lazaro MT, Balasooriya ER, Oh LM, Soderblom EJ, Lee JJ, Simmons DL, Andersen JL. EMBO Rep. 2021 Aug 9:e51136. doi: 10.15252/embr.202051136. PubMed
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Muschen M, Forostyan TV, Free S, Mercenne G, Banks CJ, Valdoz J, Whatcott CJ, Foulks JM, Bearss DJ, O'Hare T, Huang DCS, Christensen KA, Moody J, Warner SL, Tyner JW, Andersen JL. Nat Commun. 2021 Sep 9;12(1):5337. doi: 10.1038/s41467-021-25622-3. PubMed
Beta-Pix-dynamin 2 complex promotes colorectal cancer progression by facilitating membrane dynamics. Keum S, Yang SJ, Park E, Kang T, Choi JH, Jeong J, Hwang YE, Kim JW, Park D, Rhee S. Cell Oncol (Dordr). 2021 Dec;44(6):1287-1305. doi: 10.1007/s13402-021-00637-6. Epub 2021 Sep 28. PubMed
Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9. Sapozhnikov DM, Szyf M. Nat Commun. 2021 Sep 29;12(1):5711. doi: 10.1038/s41467-021-25991-9. PubMed

Associated Plasmids

TEC kinase stabilizes PLK4 to promote liver cancer metastasis. Yeung SF, Zhou Y, Zou W, Chan WL, Ching YP. Cancer Lett. 2022 Jan 1;524:70-81. doi: 10.1016/j.canlet.2021.08.038. Epub 2021 Oct 9. PubMed
Plk1 Regulates Caspase-9 Phosphorylation at Ser-196 and Apoptosis of Human Airway Smooth Muscle Cells. Liao G, Wang R, Tang DD. Am J Respir Cell Mol Biol. 2022 Feb;66(2):223-234. doi: 10.1165/rcmb.2021-0192OC. PubMed
DeltaNp63alpha promotes Epstein-Barr virus latency in undifferentiated epithelial cells. Van Sciver N, Ohashi M, Nawandar DM, Pauly NP, Lee D, Makielski KR, Bristol JA, Tsao SW, Lambert PF, Johannsen EC, Kenney SC. PLoS Pathog. 2021 Nov 8;17(11):e1010045. doi: 10.1371/journal.ppat.1010045. eCollection 2021 Nov. PubMed
A novel SARS-CoV-2 related coronavirus in bats from Cambodia. Delaune D, Hul V, Karlsson EA, Hassanin A, Ou TP, Baidaliuk A, Gambaro F, Prot M, Tu VT, Chea S, Keatts L, Mazet J, Johnson CK, Buchy P, Dussart P, Goldstein T, Simon-Loriere E, Duong V. Nat Commun. 2021 Nov 9;12(1):6563. doi: 10.1038/s41467-021-26809-4. PubMed
CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity. Long L, Wei J, Lim SA, Raynor JL, Shi H, Connelly JP, Wang H, Guy C, Xie B, Chapman NM, Fu G, Wang Y, Huang H, Su W, Saravia J, Risch I, Wang YD, Li Y, Niu M, Dhungana Y, Kc A, Zhou P, Vogel P, Yu J, Pruett-Miller SM, Peng J, Chi H. Nature. 2021 Dec;600(7888):308-313. doi: 10.1038/s41586-021-04109-7. Epub 2021 Nov 18. PubMed
Engineered small extracellular vesicles displaying ACE2 variants on the surface protect against SARS-CoV-2 infection. Kim HK, Cho J, Kim E, Kim J, Yang JS, Kim KC, Lee JY, Shin Y, Palomera LF, Park J, Baek SH, Bae HG, Cho Y, Han J, Sul JH, Lee J, Park JH, Cho YW, Lee W, Jo DG. J Extracell Vesicles. 2022 Jan;11(1):e12179. doi: 10.1002/jev2.12179. PubMed
Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling. Wang R, Wang Y, Liao G, Chen B, Panettieri RA Jr, Penn RB, Tang DD. iScience. 2022 Jan 29;25(2):103833. doi: 10.1016/j.isci.2022.103833. eCollection 2022 Feb 18. PubMed
CASPorter: A Novel Inducible Human CASP1/NALP3/ASC Inflammasome Biosensor. Zou C, Beard JA, Yang G, Evans WE, Bonten EJ. J Inflamm Res. 2022 Feb 19;15:1183-1194. doi: 10.2147/JIR.S333725. eCollection 2022. PubMed
Visualizing Spatial and Stoichiometric Barriers to Bispecific T-Cell Engager Efficacy. You R, Artichoker J, Ray A, Gonzalez Velozo H, Rock DA, Conner KP, Krummel MF. Cancer Immunol Res. 2022 Jun 3;10(6):698-712. doi: 10.1158/2326-6066.CIR-21-0594. PubMed
Extracellular vesicles enclosed-miR-421 suppresses air pollution (PM2.5 )-induced cardiac dysfunction via ACE2 signalling. Wang H, Wang T, Rui W, Xie J, Xie Y, Zhang X, Guan L, Li G, Lei Z, Schiffelers RM, Sluijter JPG, Xiao J. J Extracell Vesicles. 2022 May;11(5):e12222. doi: 10.1002/jev2.12222. PubMed
Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia. Ruan Z, Takamatsu-Yukawa K, Wang Y, Ushman ML, Labadorf AT, Ericsson M, Ikezu S, Ikezu T. Cell Rep. 2022 May 10;39(6):110791. doi: 10.1016/j.celrep.2022.110791. PubMed
SREBP1 regulates Lgals3 activation in response to cholesterol loading. Li J, Shen H, Owens GK, Guo LW. Mol Ther Nucleic Acids. 2022 May 18;28:892-909. doi: 10.1016/j.omtn.2022.05.028. eCollection 2022 Jun 14. PubMed
MPZL1 upregulation promotes tumor metastasis and correlates with unfavorable prognosis in non-small cell lung cancer. Feng J, Ouyang H, Wang J, Pan D, Sheng L, Xu C, Lin W, Hu D, Chang C, Jia D. Carcinogenesis. 2022 Jun 21. pii: 6612224. doi: 10.1093/carcin/bgac055. PubMed
The EGFR-STYK1-FGF1 axis sustains functional drug tolerance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer. Eggermont C, Giron P, Noeparast M, Vandenplas H, Aza-Blanc P, Gutierrez GJ, De Greve J. Cell Death Dis. 2022 Jul 15;13(7):611. doi: 10.1038/s41419-022-04994-4. PubMed
ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors. Rehman H, Chandrashekar DS, Balabhadrapatruni C, Nepal S, Balasubramanya SAH, Shelton AK, Skinner KR, Ma AH, Rao T, Agarwal S, Eich ML, Robinson AD, Naik G, Manne U, Netto GJ, Miller CR, Pan CX, Sonpavde G, Varambally S, Ferguson JE 3rd. JCI Insight. 2022 Aug 22;7(16):e155899. doi: 10.1172/jci.insight.155899. PubMed
FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations. Choi Y, Luo Y, Lee S, Jin H, Yoon HJ, Hahn Y, Bae J, Lee HH. Nucleic Acids Res. 2022 Aug 26;50(15):8929-8946. doi: 10.1093/nar/gkac673. PubMed
Dolutegravir Inhibits Proliferation and Motility of BT-20 Tumor Cells Through Inhibition of Human Endogenous Retrovirus Type K. Li J, Lin J, Lin JR, Farris M, Robbins L, Andrada L, Grohol B, Nong S, Liu Y. Cureus. 2022 Jul 3;14(7):e26525. doi: 10.7759/cureus.26525. eCollection 2022 Jul. PubMed
RBM45 is an m(6)A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs. Choi SH, Flamand MN, Liu B, Zhu H, Hu M, Wang M, Sewell J, Holley CL, Al-Hashimi HM, Meyer KD. Cell Rep. 2022 Aug 30;40(9):111293. doi: 10.1016/j.celrep.2022.111293. PubMed
Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964. Kelso S, O'Brien S, Kurinov I, Angers S, Sicheri F. Structure. 2022 Dec 1;30(12):1615-1625.e4. doi: 10.1016/j.str.2022.10.003. Epub 2022 Nov 2. PubMed
TRIM11, a new target of p53, facilitates the migration and invasion of nasopharyngeal carcinoma cells. Zhao Z, Deng J, Lu M, Yang J, Chen L, Li D, Sang Y. Mol Biol Rep. 2023 Jan;50(1):731-737. doi: 10.1007/s11033-022-07833-z. Epub 2022 Nov 14. PubMed
Cooperation of chromatin remodeling SWI/SNF complex and pioneer factor AP-1 shapes 3D enhancer landscapes. Wolf BK, Zhao Y, McCray A, Hawk WH, Deary LT, Sugiarto NW, LaCroix IS, Gerber SA, Cheng C, Wang X. Nat Struct Mol Biol. 2023 Jan;30(1):10-21. doi: 10.1038/s41594-022-00880-x. Epub 2022 Dec 15. PubMed
The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining. Fleury H, MacEachern MK, Stiefel CM, Anand R, Sempeck C, Nebenfuehr B, Maurer-Alcala K, Ball K, Proctor B 3rd, Belan O, Taylor E, Ortega R, Dodd B, Weatherly L, Dansoko D, Leung JW, Boulton SJ, Arnoult N. Mol Cell. 2023 May 4;83(9):1429-1445.e8. doi: 10.1016/j.molcel.2023.03.017. Epub 2023 Apr 11. PubMed
The intermediate filament protein nestin serves as a molecular hub for smooth muscle cytoskeletal signaling. Wang Y, Liao G, Wu Y, Wang R, Tang DD. Respir Res. 2023 Jun 14;24(1):157. doi: 10.1186/s12931-023-02473-8. PubMed
Chimeric antigen receptor (CAR) T cell-based targeting of CD317 as a novel immunotherapeutic strategy against glioblastoma. Hansch L, Peipp M, Mastall M, Villars D, Myburgh R, Silginer M, Weiss T, Gramatzki D, Vasella F, Manz MG, Weller M, Roth P. Neuro Oncol. 2023 Jun 19:noad108. doi: 10.1093/neuonc/noad108. PubMed
Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens. Morrison HM, Craft J, Rivera-Lugo R, Johnson JR, Golovkine GR, Bell SL, Dodd CE, Van Dis E, Beatty WL, Margolis SR, Repasy T, Shaker I, Lee AY, Vance RE, Stanley SA, Watson RO, Krogan NJ, Portnoy DA, Penn BH, Cox JS. PLoS Pathog. 2023 Jun 23;19(6):e1011088. doi: 10.1371/journal.ppat.1011088. eCollection 2023 Jun. PubMed
A modular dCas9-based recruitment platform for combinatorial epigenome editing. Swain T, Pflueger C, Freytag S, Poppe D, Pflueger J, Nguyen TV, Li JK, Lister R. Nucleic Acids Res. 2023 Nov 24:gkad1108. doi: 10.1093/nar/gkad1108. PubMed

Associated Plasmids

COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells. McHugh D, Sun B, Gutierrez-Munoz C, Hernandez-Gonzalez F, Mellone M, Guiho R, Duran I, Pombo J, Pietrocola F, Birch J, Kallemeijn WW, Khadayate S, Dharmalingam G, Vernia S, Tate EW, Martinez-Barbera JP, Withers DJ, Thomas GJ, Serrano M, Gil J. Nat Cell Biol. 2023 Dec;25(12):1804-1820. doi: 10.1038/s41556-023-01287-6. Epub 2023 Nov 27. PubMed
RNA binding proteins PTBP1 and HNRNPL regulate CFTR mRNA decay. Siddiqui A, Saxena A, Echols J, Havasi V, Fu L, Keeling KM. Heliyon. 2023 Nov 13;9(11):e22281. doi: 10.1016/j.heliyon.2023.e22281. eCollection 2023 Nov. PubMed
The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy. Broadbent DG, McEwan CM, Tsang TM, Poole DM, Naylor BC, Price JC, Schmidt JC, Andersen JL. bioRxiv [Preprint]. 2023 Nov 29:2023.11.28.569058. doi: 10.1101/2023.11.28.569058. PubMed
Stimulation Strength Determined by Superantigen Dose Controls Subcellular Localization of FOXP3 Isoforms and Suppressive Function of CD4+CD25+FOXP3+ T Cells. Lee J, Park N, Nicosia M, Park JY, Pruett SB, Seo KS. J Immunol. 2024 Feb 1;212(3):421-432. doi: 10.4049/jimmunol.2300019. PubMed
The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation. Poirier A, Ormonde JVS, Aubry I, Abidin BM, Feng CH, Martinez-Cordova Z, Hincapie AM, Wu C, Perez-Quintero LA, Wang CL, Gingras AC, Madrenas J, Tremblay ML. Sci Signal. 2024 Jan 2;17(817):eadg4422. doi: 10.1126/scisignal.adg4422. Epub 2024 Jan 2. PubMed

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