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pAAV-hSyn-DIO-hM4D(Gi)-mCherry Citations (49)

Plasmid Article: Rapid, reversible activation of AgRP neurons drives feeding behavior in mice.
Krashes MJ, Koda S, Ye C, Rogan SC, Adams AC, Cusher DS, Maratos-Flier E, Roth BL, Lowell BB J Clin Invest. 2011 Apr;121(4):1424-8. doi: 10.1172/JCI46229.
PubMed Journal

Articles Citing pAAV-hSyn-DIO-hM4D(Gi)-mCherry

Articles
Insular neural system controls decision-making in healthy and methamphetamine-treated rats. Mizoguchi H, Katahira K, Inutsuka A, Fukumoto K, Nakamura A, Wang T, Nagai T, Sato J, Sawada M, Ohira H, Yamanaka A, Yamada K. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3930-9. doi: 10.1073/pnas.1418014112. Epub 2015 Jul 6. PubMed
Direct modulation of GFAP-expressing glia in the arcuate nucleus bi-directionally regulates feeding. Chen N, Sugihara H, Kim J, Fu Z, Barak B, Sur M, Feng G, Han W. Elife. 2016 Oct 18;5. pii: e18716. doi: 10.7554/eLife.18716. PubMed
Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons. Uygun DS, Ye Z, Zecharia AY, Harding EC, Yu X, Yustos R, Vyssotski AL, Brickley SG, Franks NP, Wisden W. J Neurosci. 2016 Nov 2;36(44):11171-11184. PubMed
Chronic Loss of CA2 Transmission Leads to Hippocampal Hyperexcitability. Boehringer R, Polygalov D, Huang AJY, Middleton SJ, Robert V, Wintzer ME, Piskorowski RA, Chevaleyre V, McHugh TJ. Neuron. 2017 May 3;94(3):642-655.e9. doi: 10.1016/j.neuron.2017.04.014. PubMed
GIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behavior. Marron Fernandez de Velasco E, Zhang L, N Vo B, Tipps M, Farris S, Xia Z, Anderson A, Carlblom N, Weaver CD, Dudek SM, Wickman K. Sci Rep. 2017 May 9;7(1):1639. doi: 10.1038/s41598-017-01820-2. PubMed
Distinct Ventral Pallidal Neural Populations Mediate Separate Symptoms of Depression. Knowland D, Lilascharoen V, Pacia CP, Shin S, Wang EH, Lim BK. Cell. 2017 Jul 13;170(2):284-297.e18. doi: 10.1016/j.cell.2017.06.015. Epub 2017 Jul 6. PubMed
AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy. Morabito G, Giannelli SG, Ordazzo G, Bido S, Castoldi V, Indrigo M, Cabassi T, Cattaneo S, Luoni M, Cancellieri C, Sessa A, Bacigaluppi M, Taverna S, Leocani L, Lanciego JL, Broccoli V. Mol Ther. 2017 Dec 6;25(12):2727-2742. doi: 10.1016/j.ymthe.2017.08.004. Epub 2017 Aug 10. PubMed
A role for CA3 in social recognition memory. Chiang MC, Huang AJY, Wintzer ME, Ohshima T, McHugh TJ. Behav Brain Res. 2018 Nov 15;354:22-30. doi: 10.1016/j.bbr.2018.01.019. Epub 2018 Feb 3. PubMed
A Neural Circuit for the Suppression of Pain by a Competing Need State. Alhadeff AL, Su Z, Hernandez E, Klima ML, Phillips SZ, Holland RA, Guo C, Hantman AW, De Jonghe BC, Betley JN. Cell. 2018 Mar 22;173(1):140-152.e15. doi: 10.1016/j.cell.2018.02.057. PubMed
Serotonergic Signaling Controls Input-Specific Synaptic Plasticity at Striatal Circuits. Cavaccini A, Gritti M, Giorgi A, Locarno A, Heck N, Migliarini S, Bertero A, Mereu M, Margiani G, Trusel M, Catelani T, Marotta R, De Luca MA, Caboche J, Gozzi A, Pasqualetti M, Tonini R. Neuron. 2018 May 16;98(4):801-816.e7. doi: 10.1016/j.neuron.2018.04.008. Epub 2018 Apr 26. PubMed
Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons. Ueno M, Nakamura Y, Li J, Gu Z, Niehaus J, Maezawa M, Crone SA, Goulding M, Baccei ML, Yoshida Y. Cell Rep. 2018 May 1;23(5):1286-1300.e7. doi: 10.1016/j.celrep.2018.03.137. PubMed
Pyramidal cell regulation of interneuron survival sculpts cortical networks. Wong FK, Bercsenyi K, Sreenivasan V, Portales A, Fernandez-Otero M, Marin O. Nature. 2018 May;557(7707):668-673. doi: 10.1038/s41586-018-0139-6. Epub 2018 May 30. PubMed
Activation of GABAergic Neurons in the Nucleus Accumbens Mediates the Expression of Cocaine-Associated Memory. Zhang T, Deyama S, Domoto M, Wada S, Yanagida J, Sasase H, Hinoi E, Nishitani N, Nagayasu K, Kaneko S, Kaneda K. Biol Pharm Bull. 2018;41(7):1084-1088. doi: 10.1248/bpb.b18-00221. PubMed
SCN VIP Neurons Are Essential for Normal Light-Mediated Resetting of the Circadian System. Jones JR, Simon T, Lones L, Herzog ED. J Neurosci. 2018 Sep 12;38(37):7986-7995. doi: 10.1523/JNEUROSCI.1322-18.2018. Epub 2018 Aug 6. PubMed
Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress. Alpar A, Zahola P, Hanics J, Hevesi Z, Korchynska S, Benevento M, Pifl C, Zachar G, Perugini J, Severi I, Leitgeb P, Bakker J, Miklosi AG, Tretiakov E, Keimpema E, Arque G, Tasan RO, Sperk G, Malenczyk K, Mate Z, Erdelyi F, Szabo G, Lubec G, Palkovits M, Giordano A, Hokfelt TG, Romanov RA, Horvath TL, Harkany T. EMBO J. 2018 Nov 2;37(21). pii: embj.2018100087. doi: 10.15252/embj.2018100087. Epub 2018 Sep 12. PubMed
A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics. Meira T, Leroy F, Buss EW, Oliva A, Park J, Siegelbaum SA. Nat Commun. 2018 Oct 9;9(1):4163. doi: 10.1038/s41467-018-06501-w. PubMed
Global Connectivity and Function of Descending Spinal Input Revealed by 3D Microscopy and Retrograde Transduction. Wang Z, Maunze B, Wang Y, Tsoulfas P, Blackmore MG. J Neurosci. 2018 Dec 5;38(49):10566-10581. doi: 10.1523/JNEUROSCI.1196-18.2018. Epub 2018 Oct 19. PubMed
Hypothalamic Neurons that Regulate Feeding Can Influence Sleep/Wake States Based on Homeostatic Need. Goldstein N, Levine BJ, Loy KA, Duke WL, Meyerson OS, Jamnik AA, Carter ME. Curr Biol. 2018 Dec 3;28(23):3736-3747.e3. doi: 10.1016/j.cub.2018.09.055. Epub 2018 Nov 21. PubMed
Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State. Li C, Navarrete J, Liang-Guallpa J, Lu C, Funderburk SC, Chang RB, Liberles SD, Olson DP, Krashes MJ. Cell Metab. 2019 Mar 5;29(3):681-694.e5. doi: 10.1016/j.cmet.2018.10.016. Epub 2018 Nov 21. PubMed
GABA and glutamate neurons in the VTA regulate sleep and wakefulness. Yu X, Li W, Ma Y, Tossell K, Harris JJ, Harding EC, Ba W, Miracca G, Wang D, Li L, Guo J, Chen M, Li Y, Yustos R, Vyssotski AL, Burdakov D, Yang Q, Dong H, Franks NP, Wisden W. Nat Neurosci. 2019 Jan;22(1):106-119. doi: 10.1038/s41593-018-0288-9. Epub 2018 Dec 17. PubMed
Ventral Pallidum Is the Primary Target for Accumbens D1 Projections Driving Cocaine Seeking. Pardo-Garcia TR, Garcia-Keller C, Penaloza T, Richie CT, Pickel J, Hope BT, Harvey BK, Kalivas PW, Heinsbroek JA. J Neurosci. 2019 Mar 13;39(11):2041-2051. doi: 10.1523/JNEUROSCI.2822-18.2018. Epub 2019 Jan 8. PubMed
Nucleus Accumbens Drd1-Expressing Neurons Control Aggression Self-Administration and Aggression Seeking in Mice. Golden SA, Jin M, Heins C, Venniro M, Michaelides M, Shaham Y. J Neurosci. 2019 Mar 27;39(13):2482-2496. doi: 10.1523/JNEUROSCI.2409-18.2019. Epub 2019 Jan 17. PubMed
Genetic lesioning of histamine neurons increases sleep-wake fragmentation and reveals their contribution to modafinil-induced wakefulness. Yu X, Ma Y, Harding EC, Yustos R, Vyssotski AL, Franks NP, Wisden W. Sleep. 2019 May 1;42(5). pii: 5307017. doi: 10.1093/sleep/zsz031. PubMed
Spatial and Temporal Locomotor Learning in Mouse Cerebellum. Darmohray DM, Jacobs JR, Marques HG, Carey MR. Neuron. 2019 Apr 3;102(1):217-231.e4. doi: 10.1016/j.neuron.2019.01.038. Epub 2019 Feb 19. PubMed
Long-range inhibitory intersection of a retrosplenial thalamocortical circuit by apical tuft-targeting CA1 neurons. Yamawaki N, Li X, Lambot L, Ren LY, Radulovic J, Shepherd GMG. Nat Neurosci. 2019 Apr;22(4):618-626. doi: 10.1038/s41593-019-0355-x. Epub 2019 Mar 11. PubMed
The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits. Li MM, Madara JC, Steger JS, Krashes MJ, Balthasar N, Campbell JN, Resch JM, Conley NJ, Garfield AS, Lowell BB. Neuron. 2019 May 8;102(3):653-667.e6. doi: 10.1016/j.neuron.2019.02.028. Epub 2019 Mar 14. PubMed
Central Amygdala Prepronociceptin-Expressing Neurons Mediate Palatable Food Consumption and Reward. Hardaway JA, Halladay LR, Mazzone CM, Pati D, Bloodgood DW, Kim M, Jensen J, DiBerto JF, Boyt KM, Shiddapur A, Erfani A, Hon OJ, Neira S, Stanhope CM, Sugam JA, Saddoris MP, Tipton G, McElligott Z, Jhou TC, Stuber GD, Bruchas MR, Bulik CM, Holmes A, Kash TL. Neuron. 2019 Jun 5;102(5):1037-1052.e7. doi: 10.1016/j.neuron.2019.03.037. Epub 2019 Apr 24. PubMed
Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics. Adam Y, Kim JJ, Lou S, Zhao Y, Xie ME, Brinks D, Wu H, Mostajo-Radji MA, Kheifets S, Parot V, Chettih S, Williams KJ, Gmeiner B, Farhi SL, Madisen L, Buchanan EK, Kinsella I, Zhou D, Paninski L, Harvey CD, Zeng H, Arlotta P, Campbell RE, Cohen AE. Nature. 2019 May 1. pii: 10.1038/s41586-019-1166-7. doi: 10.1038/s41586-019-1166-7. PubMed

Associated Plasmids

Sensory perception drives food avoidance through excitatory basal forebrain circuits. Patel JM, Swanson J, Ung K, Herman A, Hanson E, Ortiz-Guzman J, Selever J, Tong Q, Arenkiel BR. Elife. 2019 May 10;8. pii: 44548. doi: 10.7554/eLife.44548. PubMed
Nicotine excites VIP interneurons to disinhibit pyramidal neurons in auditory cortex. Askew CE, Lopez AJ, Wood MA, Metherate R. Synapse. 2019 Sep;73(9):e22116. doi: 10.1002/syn.22116. Epub 2019 May 17. PubMed
Stable Representations of Decision Variables for Flexible Behavior. Bari BA, Grossman CD, Lubin EE, Rajagopalan AE, Cressy JI, Cohen JY. Neuron. 2019 Sep 4;103(5):922-933.e7. doi: 10.1016/j.neuron.2019.06.001. Epub 2019 Jul 4. PubMed
Distinct roles of striatal direct and indirect pathways in value-based decision making. Kwak S, Jung MW. Elife. 2019 Jul 16;8. pii: 46050. doi: 10.7554/eLife.46050. PubMed
The Lateral Hypothalamic and BNST GABAergic Projections to the Anterior Ventrolateral Periaqueductal Gray Regulate Feeding. Hao S, Yang H, Wang X, He Y, Xu H, Wu X, Pan L, Liu Y, Lou H, Xu H, Ma H, Xi W, Zhou Y, Duan S, Wang H. Cell Rep. 2019 Jul 16;28(3):616-624.e5. doi: 10.1016/j.celrep.2019.06.051. PubMed
The Stability of Glutamatergic Synapses Is Independent of Activity Level, but Predicted by Synapse Size. Quinn DP, Kolar A, Harris SA, Wigerius M, Fawcett JP, Krueger SR. Front Cell Neurosci. 2019 Jun 27;13:291. doi: 10.3389/fncel.2019.00291. eCollection 2019. PubMed
Prefrontal cortex neuronal ensembles encoding fear drive fear expression during long-term memory retrieval. Giannotti G, Heinsbroek JA, Yue AJ, Deisseroth K, Peters J. Sci Rep. 2019 Jul 24;9(1):10709. doi: 10.1038/s41598-019-47095-7. PubMed
A Paranigral VTA Nociceptin Circuit that Constrains Motivation for Reward. Parker KE, Pedersen CE, Gomez AM, Spangler SM, Walicki MC, Feng SY, Stewart SL, Otis JM, Al-Hasani R, McCall JG, Sakers K, Bhatti DL, Copits BA, Gereau RW, Jhou T, Kash TJ, Dougherty JD, Stuber GD, Bruchas MR. Cell. 2019 Jul 25;178(3):653-671.e19. doi: 10.1016/j.cell.2019.06.034. PubMed
Neuronal Activation Stimulates Cytomegalovirus Promoter-Driven Transgene Expression. Back S, Dossat A, Parkkinen I, Koivula P, Airavaara M, Richie CT, Chen YH, Wang Y, Harvey BK. Mol Ther Methods Clin Dev. 2019 Jul 3;14:180-188. doi: 10.1016/j.omtm.2019.06.006. eCollection 2019 Sep 13. PubMed
Complementary Genetic Targeting and Monosynaptic Input Mapping Reveal Recruitment and Refinement of Distributed Corticostriatal Ensembles by Cocaine. Wall NR, Neumann PA, Beier KT, Mokhtari AK, Luo L, Malenka RC. Neuron. 2019 Dec 4;104(5):916-930.e5. doi: 10.1016/j.neuron.2019.10.032. Epub 2019 Nov 20. PubMed
An Excitatory and Epileptogenic Effect of Dentate Gyrus Mossy Cells in a Mouse Model of Epilepsy. Botterill JJ, Lu YL, LaFrancois JJ, Bernstein HL, Alcantara-Gonzalez D, Jain S, Leary P, Scharfman HE. Cell Rep. 2019 Nov 26;29(9):2875-2889.e6. doi: 10.1016/j.celrep.2019.10.100. PubMed
Complementary Roles for Ventral Pallidum Cell Types and Their Projections in Relapse. Prasad AA, Xie C, Chaichim C, Nguyen JH, McClusky HE, Killcross S, Power JM, McNally GP. J Neurosci. 2020 Jan 22;40(4):880-893. doi: 10.1523/JNEUROSCI.0262-19.2019. Epub 2019 Dec 9. PubMed
Kisspeptin neuron-specific and self-sustained calcium oscillation in the hypothalamic arcuate nucleus of neonatal mice: Regulatory factors of its synchronization. Kim D, Jang S, Kim J, Park I, Ku K, Choi M, Lee S, Heo WD, Son GH, Choe HK, Kim K. Neuroendocrinology. 2020 Jan 15. pii: 000505922. doi: 10.1159/000505922. PubMed
Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding. Cheng W, Gonzalez I, Pan W, Tsang AH, Adams J, Ndoka E, Gordian D, Khoury B, Roelofs K, Evers SS, MacKinnon A, Wu S, Frikke-Schmidt H, Flak JN, Trevaskis JL, Rhodes CJ, Fukada SI, Seeley RJ, Sandoval DA, Olson DP, Blouet C, Myers MG Jr. Cell Metab. 2020 Feb 4;31(2):301-312.e5. doi: 10.1016/j.cmet.2019.12.012. Epub 2020 Jan 16. PubMed
Chemogenetic inhibition in the dorsal striatum reveals regional specificity of direct and indirect pathway control of action sequencing. Garr E, Delamater AR. Neurobiol Learn Mem. 2020 Mar;169:107169. doi: 10.1016/j.nlm.2020.107169. Epub 2020 Jan 20. PubMed
A Novel Next-Generation Sequencing and Analysis Platform to Assess the Identity of Recombinant Adeno-Associated Viral Preparations from Viral DNA Extracts. Guerin K, Rego M, Bourges D, Ersing I, Haery L, Harten DeMaio K, Sanders E, Tasissa M, Kostman M, Tillgren M, Makana Hanley L, Mueller I, Mitsopoulos A, Fan M. Hum Gene Ther. 2020 Jun;31(11-12):664-678. doi: 10.1089/hum.2019.277. Epub 2020 Apr 15. PubMed
Excitatory VTA to DH projections provide a valence signal to memory circuits. Han Y, Zhang Y, Kim H, Grayson VS, Jovasevic V, Ren W, Centeno MV, Guedea AL, Meyer MAA, Wu Y, Gutruf P, Surmeier DJ, Gao C, Martina M, Apkarian AV, Rogers JA, Radulovic J. Nat Commun. 2020 Mar 19;11(1):1466. doi: 10.1038/s41467-020-15035-z. PubMed
Individual differences in stereotypy and neuron subtype translatome with TrkB deletion. Engeln M, Song Y, Chandra R, La A, Fox ME, Evans B, Turner MD, Thomas S, Francis TC, Hertzano R, Lobo MK. Mol Psychiatry. 2020 May 4. pii: 10.1038/s41380-020-0746-0. doi: 10.1038/s41380-020-0746-0. PubMed
Chemogenetic Inhibition of Dopamine D1-expressing Neurons in the Dorsal Striatum does not alter Methamphetamine Intake in either Male or Female Long Evans Rats. Job MO, Chojnacki MR, Daiwile AP, Cadet JL. Neurosci Lett. 2020 Jun 11;729:134987. doi: 10.1016/j.neulet.2020.134987. Epub 2020 May 1. PubMed
Complex Movement Control in a Rat Model of Parkinsonian Falls: Bidirectional Control by Striatal Cholinergic Interneurons. Avila C, Kucinski A, Sarter M. J Neurosci. 2020 Jul 29;40(31):6049-6067. doi: 10.1523/JNEUROSCI.0220-20.2020. Epub 2020 Jun 18. PubMed
Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior. Yu X, Ba W, Zhao G, Ma Y, Harding EC, Yin L, Wang D, Li H, Zhang P, Shi Y, Yustos R, Vyssotski AL, Dong H, Franks NP, Wisden W. Mol Psychiatry. 2020 Jun 17. pii: 10.1038/s41380-020-0810-9. doi: 10.1038/s41380-020-0810-9. PubMed

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