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5HRE/GFP Citations (11)

Plasmid Article: Green fluorescent protein is a suitable reporter of tumor hypoxia despite an oxygen requirement for chromophore formation.
Vordermark D, Shibata T, Brown JM Neoplasia. 2001 Nov-Dec;3(6):527-34.
PubMed Journal

Articles Citing 5HRE/GFP

A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level. Erapaneedi R, Belousov VV, Schafers M, Kiefer F. EMBO J. 2016 Jan 4;35(1):102-13. doi: 10.15252/embj.201592775. Epub 2015 Nov 23. PubMed
Oxygen as a chemoattractant: confirming cellular hypoxia in paper-based invasion assays. Truong AS, Lockett MR. Analyst. 2016 Jun 21;141(12):3874-82. doi: 10.1039/c6an00630b. Epub 2016 May 3. PubMed
Gene delivery of hypoxia-inducible VEGF targeting collagen effectively improves cardiac function after myocardial infarction. Xia JB, Wu HY, Lai BL, Zheng L, Zhou DC, Chang ZS, Mao CZ, Liu GH, Park KS, Zhao H, Kim SK, Song GH, Cai DQ, Qi XF. Sci Rep. 2017 Oct 16;7(1):13273. doi: 10.1038/s41598-017-13547-1. PubMed
The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells. Kim H, Lin Q, Glazer PM, Yun Z. Breast Cancer Res. 2018 Mar 6;20(1):16. doi: 10.1186/s13058-018-0944-8. PubMed
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR. Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV. Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009. Epub 2018 May 31. PubMed

Associated Plasmids

Induction of HIF-1alpha by HIV-1 Infection in CD4(+) T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation. Duette G, Pereyra Gerber P, Rubione J, Perez PS, Landay AL, Crowe SM, Liao Z, Witwer KW, Holgado MP, Salido J, Geffner J, Sued O, Palmer CS, Ostrowski M. MBio. 2018 Sep 11;9(5). pii: mBio.00757-18. doi: 10.1128/mBio.00757-18. PubMed
Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model. Ayuso JM, Truttschel R, Gong MM, Humayun M, Virumbrales-Munoz M, Vitek R, Felder M, Gillies SD, Sondel P, Wisinski KB, Patankar M, Beebe DJ, Skala MC. Oncoimmunology. 2018 Dec 12;8(3):1553477. doi: 10.1080/2162402X.2018.1553477. eCollection 2019. PubMed
The focal adhesion protein kindlin-2 controls mitotic spindle assembly by inhibiting histone deacetylase 6 and maintaining alpha-tubulin acetylation. Tan HF, Tan SM. J Biol Chem. 2020 May 1;295(18):5928-5943. doi: 10.1074/jbc.RA120.012954. Epub 2020 Mar 13. PubMed
Isolinderalactone suppresses human glioblastoma growth and angiogenic activity in 3D microfluidic chip and in vivo mouse models. Park JH, Kim MJ, Kim WJ, Kwon KD, Ha KT, Choi BT, Lee SY, Shin HK. Cancer Lett. 2020 May 28;478:71-81. doi: 10.1016/j.canlet.2020.03.009. Epub 2020 Mar 12. PubMed
Generating linear oxygen gradients across 3D cell cultures with block-layered oxygen controlled chips (BLOCCs). Boyce MW, Simke WC, Kenney RM, Lockett MR. Anal Methods. 2020 Jan 7;12(1):18-24. doi: 10.1039/C9AY01690B. Epub 2019 Nov 26. PubMed
Microfluidic Tumor-on-a-Chip Model to Study Tumor Metabolic Vulnerability. Ayuso JM, Rehman S, Farooqui M, Virumbrales-Munoz M, Setaluri V, Skala MC, Beebe DJ. Int J Mol Sci. 2020 Nov 28;21(23). pii: ijms21239075. doi: 10.3390/ijms21239075. PubMed

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