Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Addgene is open for ordering and depositing; find up-to-date details here. To learn more about how we are supporting COVID-19 research and to find related plasmids, check out our COVID-19 and Coronavirus Plasmids & Resources page.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

pMLM3705 Citations (12)

Plasmid Article: CRISPR RNA-guided activation of endogenous human genes.
Maeder ML, Linder SJ, Cascio VM, Fu Y, Ho QH, Joung JK Nat Methods. 2013 Jul 25. doi: 10.1038/nmeth.2598.
PubMed Journal

Articles Citing pMLM3705

A prominent and conserved role for YY1 in Xist transcriptional activation. Makhlouf M, Ouimette JF, Oldfield A, Navarro P, Neuillet D, Rougeulle C. Nat Commun. 2014 Sep 11;5:4878. doi: 10.1038/ncomms5878. PubMed
Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display. Shechner DM, Hacisuleyman E, Younger ST, Rinn JL. Nat Methods. 2015 Jul;12(7):664-70. doi: 10.1038/nmeth.3433. Epub 2015 Jun 1. PubMed

Associated Plasmids

Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome. Muller M, Lee CM, Gasiunas G, Davis TH, Cradick TJ, Siksnys V, Bao G, Cathomen T, Mussolino C. Mol Ther. 2015 Dec 14. doi: 10.1038/mt.2015.218. PubMed
Engineering Synthetic Gene Circuits in Living Cells with CRISPR Technology. Jusiak B, Cleto S, Perez-Pinera P, Lu TK. Trends Biotechnol. 2016 Jan 22. pii: S0167-7799(15)00274-7. doi: 10.1016/j.tibtech.2015.12.014. PubMed
Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner. Cano-Rodriguez D, Gjaltema RA, Jilderda LJ, Jellema P, Dokter-Fokkens J, Ruiters MH, Rots MG. Nat Commun. 2016 Aug 10;7:12284. doi: 10.1038/ncomms12284. PubMed
Rewiring human cellular input-output using modular extracellular sensors. Schwarz KA, Daringer NM, Dolberg TB, Leonard JN. Nat Chem Biol. 2016 Dec 12. doi: 10.1038/nchembio.2253. PubMed

Associated Plasmids

PhiReX: a programmable and red light-regulated protein expression switch for yeast. Hochrein L, Machens F, Messerschmidt K, Mueller-Roeber B. Nucleic Acids Res. 2017 Sep 6;45(15):9193-9205. doi: 10.1093/nar/gkx610. PubMed
Synthetic Promoters and Transcription Factors for Heterologous Protein Expression in Saccharomyces cerevisiae. Machens F, Balazadeh S, Mueller-Roeber B, Messerschmidt K. Front Bioeng Biotechnol. 2017 Oct 19;5:63. doi: 10.3389/fbioe.2017.00063. eCollection 2017. PubMed
Establishment of Cell Lines Stably Expressing dCas9-Fusions to Address Kinetics of Epigenetic Editing. Goubert D, Koncz M, Kiss A, Rots MG. Methods Mol Biol. 2018;1767:395-415. doi: 10.1007/978-1-4939-7774-1_22. PubMed

Associated Plasmids

Enhancing the Translational Capacity of E. coli by Resolving the Codon Bias. Lipinszki Z, Vernyik V, Farago N, Sari T, Puskas LG, Blattner FR, Posfai G, Gyorfy Z. ACS Synth Biol. 2018 Nov 16;7(11):2656-2664. doi: 10.1021/acssynbio.8b00332. Epub 2018 Nov 2. PubMed
Targeted removal of epigenetic barriers during transcriptional reprogramming. Baumann V, Wiesbeck M, Breunig CT, Braun JM, Koferle A, Ninkovic J, Gotz M, Stricker SH. Nat Commun. 2019 May 9;10(1):2119. doi: 10.1038/s41467-019-10146-8. PubMed
KRAB-Induced Heterochromatin Effectively Silences PLOD2 Gene Expression in Somatic Cells and is Resilient to TGFbeta1 Activation. Gjaltema RAF, Goubert D, Huisman C, Pilar Garcia Tobilla CD, Koncz M, Jellema PG, Wu D, Brouwer U, Kiss A, Verschure PJ, Bank RA, Rots MG. Int J Mol Sci. 2020 May 21;21(10). pii: ijms21103634. doi: 10.3390/ijms21103634. PubMed

If you have published an article using this plasmid, please email us at [email protected] to have your article added to this page.