Mouse genome-wide lentiviral CRISPR gRNA library version 2 Citations (18)
Originally described in: A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M, Ohnishi S, Cooper J, Patel M, McKerrell T, Chen B, Domingues AF, Gallipoli P, Teichmann S, Ponstingl H, McDermott U, Saez-Rodriguez J, Huntly BJ, Iorio F, Pina C, Vassiliou GS, Yusa K Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079. PubMed Journal
Articles Citing Mouse genome-wide lentiviral CRISPR gRNA library version 2
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Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation.
Henriksson J, Chen X, Gomes T, Ullah U, Meyer KB, Miragaia R, Duddy G, Pramanik J, Yusa K, Lahesmaa R, Teichmann SA.
Cell. 2019 Jan 7. pii: S0092-8674(18)31569-1. doi: 10.1016/j.cell.2018.11.044.
PubMed
Associated Plasmids |
CRISPR-KO screen identifies Dmap1 as a regulator of chemically-induced reprogramming and differentiation of cardiac progenitors.
Yu JSL, Palano G, Lim C, Moggio A, Drowley L, Plowright AT, Bohlooly-Y M, Rosen BS, Hansson EM, Wang QD, Yusa K.
Stem Cells. 2019 Apr 1. doi: 10.1002/stem.3012.
PubMed
Associated Plasmids |
| Beta-binomial modeling of CRISPR pooled screen data identifies target genes with greater sensitivity and fewer false negatives. Jeong HH, Kim SY, Rousseaux MWC, Zoghbi HY, Liu Z. Genome Res. 2019 Jun;29(6):999-1008. doi: 10.1101/gr.245571.118. Epub 2019 Apr 23. PubMed |
| Establishment of a system for screening autophagic flux regulators using a modified fluorescent reporter and CRISPR/Cas9. Yazawa R, Nishida Y, Aoyama S, Tanida I, Miyatsuka T, Suzuki L, Himuro M, Haruna H, Takubo N, Shimizu T, Watada H. Biochem Biophys Res Commun. 2019 Aug 27;516(3):686-692. doi: 10.1016/j.bbrc.2019.06.129. Epub 2019 Jun 26. PubMed |
| Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination. Chen CC, Chen BR, Wang Y, Curman P, Beilinson HA, Brecht RM, Liu CC, Farrell RJ, de Juan-Sanz J, Charbonnier LM, Kajimura S, Ryan TA, Schatz DG, Chatila TA, Wikstrom JD, Tyler JK, Sleckman BP. J Exp Med. 2021 Aug 2;218(8). pii: 212182. doi: 10.1084/jem.20201708. Epub 2021 May 25. PubMed |
| In vivo CRISPR-Cas9 knockout screening using quantitative PCR identifies thymosin beta-4 X-linked that promotes diffuse-type gastric cancer metastasis. An HW, Kim SY, Kwon JW, Seok SH, Woo SH, Kim DY, Park JW. Mol Carcinog. 2021 Sep;60(9):597-606. doi: 10.1002/mc.23326. Epub 2021 Jun 3. PubMed |
| LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells. Chen BR, Wang Y, Tubbs A, Zong D, Fowler FC, Zolnerowich N, Wu W, Bennett A, Chen CC, Feng W, Nussenzweig A, Tyler JK, Sleckman BP. Elife. 2021 Sep 3;10. pii: 68466. doi: 10.7554/eLife.68466. PubMed |
| In vivo genome-wide CRISPR screens identify SOCS1 as intrinsic checkpoint of CD4(+) TH1 cell response. Sutra Del Galy A, Menegatti S, Fuentealba J, Lucibello F, Perrin L, Helft J, Darbois A, Saitakis M, Tosello J, Rookhuizen D, Deloger M, Gestraud P, Socie G, Amigorena S, Lantz O, Menger L. Sci Immunol. 2021 Dec 3;6(66):eabe8219. doi: 10.1126/sciimmunol.abe8219. Epub 2021 Dec 3. PubMed |
| A Whole Genome CRISPR/Cas9 Screening Approach for Identifying Genes Encoding DNA End-Processing Proteins. Chen BR, Sleckman BP. Methods Mol Biol. 2022;2444:15-27. doi: 10.1007/978-1-0716-2063-2_2. PubMed |
| DNA-PK promotes DNA end resection at DNA double strand breaks in G(0) cells. Fowler FC, Chen BR, Zolnerowich N, Wu W, Pavani R, Paiano J, Peart C, Chen Z, Nussenzweig A, Sleckman BP, Tyler JK. Elife. 2022 May 16;11:e74700. doi: 10.7554/eLife.74700. PubMed |
| HIRA loss transforms FH-deficient cells. Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, Harle V, Offord V, Wong K, Mora A, Speed A, Caraffini V, Tran MGB, Maher ER, Stewart GD, Vanharanta S, Adams DJ, Frezza C. Sci Adv. 2022 Oct 21;8(42):eabq8297. doi: 10.1126/sciadv.abq8297. Epub 2022 Oct 21. PubMed |
| B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factors. Kaemena DF, Yoshihara M, Beniazza M, Ashmore J, Zhao S, Bertenstam M, Olariu V, Katayama S, Okita K, Tomlinson SR, Yusa K, Kaji K. Nat Commun. 2023 Jan 30;14(1):488. doi: 10.1038/s41467-023-36097-9. PubMed |
| Genome-wide screening for regulators of degradation of insulin secretory granules with a fluorescent reporter. Kanai A, Nishida Y, Iwamoto T, Yokota M, Aoyama S, Ueki K, Ito M, Uzawa H, Iida H, Koike M, Watada H. Biochem Biophys Res Commun. 2023 Jul 20;676:132-140. doi: 10.1016/j.bbrc.2023.07.040. PubMed |
| Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency. Kwon JW, Oh JS, Seok SH, An HW, Lee YJ, Lee NY, Ha T, Kim HA, Yoon GM, Kim SE, Oh PR, Lee SH, Voon DC, Kim DY, Park JW. Mol Cancer. 2023 Sep 20;22(1):156. doi: 10.1186/s12943-023-01857-0. PubMed |
| Functional CRISPR screens in T cells reveal new opportunities for cancer immunotherapies. Xiang M, Li H, Zhan Y, Ma D, Gao Q, Fang Y. Mol Cancer. 2024 Apr 5;23(1):73. doi: 10.1186/s12943-024-01987-z. PubMed |
| Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7. Li C, Fu J, Shao S, Luo ZQ. PLoS Pathog. 2024 May 13;20(5):e1011783. doi: 10.1371/journal.ppat.1011783. eCollection 2024 May. PubMed |
The interferon gamma pathway enhances pluripotency and X-chromosome reactivation in iPSC reprogramming.
Barrero M, Lazarenkov A, Blanco E, Palma LG, Lopez-Rubio AV, Bauer M, Bigas A, Di Croce L, Sardina JL, Payer B.
Sci Adv. 2024 Aug 9;10(32):eadj8862. doi: 10.1126/sciadv.adj8862. Epub 2024 Aug 7.
PubMed
Associated Plasmids |
| Transcriptional inhibition after irradiation occurs preferentially at highly expressed genes in a manner dependent on cell cycle progression. Chen Z, Wang X, Gao X, Arslanovic N, Chen K, Tyler JK. Elife. 2024 Oct 11;13:RP94001. doi: 10.7554/eLife.94001. PubMed |
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