Addgene's CRISPR collection includes plasmids for gene disruption, RNA base editing, pooled library screening, and more.
Addgene's COVID-19 collection includes plasmids expressing SARS-CoV-2 open reading frames, ACE2, TMPRSS2, FURIN, and more.
Addgene's repository contains over 100,000 plasmids. Browse by gene, vector type, expression system, or depositing lab.
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Depositor: Gordon Fishell
Purpose: Ready-to-use AAV Retrograde particles produced from pAAV-hDlx-GqDREADD-dTomato-Fishell-4 (#83897). hDlx-driven expression of GqDREADD (hM3D) and nuclear localized dTomato (physically separate) for activation of interneurons. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.
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Addgene has been an exceptionally useful resource for us, both because they can be trusted to supply our plasmids to other labs efficiently, and because we ourselves are constantly ordering reagents of interest that other labs have deposited. Keep up the good work!
Dr. Anjana Rao
La Jolla Institute for Immunology
(La Jolla, CA)
Our optogenetic tools are sweeping throughout neuroscience, helping scientists figure out how the brain works. Without Addgene helping provide these to the world, neuroscience would be moving at a much slower pace.
Dr. Ed Boyden
Massachusetts Institute of Technology
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