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Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
Yurkovetskiy L, Wang X, Pascal KE, Tomkins-Tinch C, Nyalile TP, Wang Y, Baum A, Diehl WE, Dauphin A, Carbone C, Veinotte K, Egri SB, Schaffner SF, Lemieux JE, Munro JB, Rafique A, Barve A, Sabeti PC, Kyratsous CA, Dudkina NV, Shen K, Luban J
Cell. 2020 Sep 15. pii: S0092-8674(20)31229-0. doi: 10.1016/j.cell.2020.09.032.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
158074pcDNA3.1 SARS-CoV-2 S D614Expresses SARS-CoV-2 spike protein
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158075pcDNA3.1 SARS-CoV-2 S D614GExpresses SARS-CoV-2 spike protein with a D614G mutation
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158076pcDNA3.1 SARS-CoV-2 S D614-truncExpresses SARS-CoV-2 spike protein with a truncation
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158077pcDNA3.1 SARS-CoV-2 S D614G-truncExpresses SARS-CoV-2 spike protein with a D614G truncated mutation
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158078pcDNA3.1 SARS-CoV-2 MExpresses SARS-CoV-2 membrane protein in mammalian cells
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158079pcDNA3.1 SARS-CoV-2 NExpresses SARS-CoV-2 nucleocapsid protein in mammalian cells
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158080pcDNA3.1 SARS-CoV-2 EExpresses SARS-CoV-2 envelope protein in mammalian cells
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158081pscALPSpuro-HsACE2 (human)Expresses human ACE2 in mammalian cells
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158082pscALPSpuro-FcACE2 (Cat)Expresses cat ACE2 in mammalian cells
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158083pscALPSpuro-ClACE2 (Dog)Expresses dog ACE2 in mammalian cells
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158084pscALPSpuro-MjACE2 (Pangolin)Expresses pangolin ACE2 in mammalian cells
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158085pscALPSpuro-SsACE2 (Pig)Expresses pig ACE2 in mammalian cells
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158086pscALPSpuro-RnACE2 (Rat)Expresses rat ACE2 in mammalian cells
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158087pscALPSpuro-MmACE2 (Mouse)Expresses mouse ACE2 in mammalian cells
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158088pscALPSblasti-TMPRSS2 BlastiExpresses TMPRSS2 in mammalian cells
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158089pCAGGS-ACE2-his expression plasmidExpresses ACE2 in mammalian cells
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159665pscALPSpuro-RsACE2Expresses Rhinolophus sinicus ACE2 in mammalian cells
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164651pCAGGS D614G soluble SpikeExpresses SARS-CoV-2 soluble Spike protein with a D614G mutation
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164652pCAGGS D614 soluble SpikeExpresses SARS-CoV-2 soluble Spike protein
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Recombinant Antibodies from Article