We narrowed to 638 results for: HR2

1. pAAV-EF1a-SwitchON_mRubyNLS-hChR2(H134R)-EYFP-NO_WPRE

   Plasmid

   #118279

   Purpose

   Expresses mRuby2 in the nucleus of Cre-negative cells, and ChR(H134R)-YFP in Cre-positive cells

   Depositor

   Dietmar Schmitz

   Article

   Wozny et al Front Cell Neurosci. 2018 Oct 2;12:337.

   Inserts

   mRuby2
   ChR2(H134R)
   

   Use

   AAV and Cre/Lox

   Tags

   SV40 NLS and YFP

   Expression

   Mutation

   Promoter

   EF1 alpha

   Available since

   Dec. 5, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV CaMKIIa ChR2 E90R D156N T159C 2A tDimer

   Plasmid

   #52878

   Purpose

   Chloride-conducting Channelrhodopsin with slow kinetics, neuron-specific promoter, plus red fluorescent protein, excitatory neurons

   Depositor

   Thomas Oertner

   Article

   Wietek et al Science. 2014 Mar 27.

   Inserts

   Channelrhodopsin-2
   red fluorescent protein
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   E90R, D156N, T159C

   Promoter

   CaMKIIa

   Available since

   July 16, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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3. Vsx2 hR2-20 +SV40 base prom-GFP-IRES-AP

   Plasmid

   #225883

   Purpose

   Enhancer reporter

   Depositor

   Michael Dyer

   Insert

   hR2-20
   

   Use

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   April 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pOTTC1845 - pAAV CaMKII hChR2(H134R)-V5-ER-LBD (ChRERa)

   Plasmid

   #201822

   Purpose

   An adeno-associated viral vector expressing channelrhodopsin-2 fused to a V5 epitope and the ligand-binding domain of estrogen receptor (ChRERa) from a CaMKii promoter, for use in PET imaging

   Depositor

   Christopher Richie

   Article

   Bonaventura et al Sci Transl Med. 2023 Jul 26;15(706):eadd

   Insert

   hChR2(H134R)-V5-ER-LBD (ChRERa)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   CaMKii

   Available since

   Oct. 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. HCT163_pAAV-eHGT_3Xcore_1137m-minBGprom-ChR2(H134R)-EYFP-WPRE3-bGHpA

   Plasmid

   #233562

   Purpose

   Direct-expressing ChR2(H134R)-EYFP AAV virus

   Depositor

   Tanya Daigle, The Allen Institute for Brain Science

   Article

   Kussick et al Cell Rep. 2025 Jun 24;44(6):115730. doi:

   Insert

   ChR2(H134R)-EYFP
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   minBglobin

   Available since

   June 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. HCT164_pAAV-3X-eHGT_1139m-minBGprom-ChR2(H134R)-EYFP-WPRE3-bGHpA

   Plasmid

   #233563

   Purpose

   Direct-expressing ChR2(H134R)-EYFP AAV virus

   Depositor

   Tanya Daigle, The Allen Institute for Brain Science

   Article

   Kussick et al Cell Rep. 2025 Jun 24;44(6):115730. doi:

   Insert

   ChR2(H134R)-EYFP
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   minBglobin

   Available since

   June 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pOTTC1822 - pAAV SYN1 DIO hChR2(H134R)-V5-ER-LBD (ChRERa)

   Plasmid

   #201821

   Purpose

   An adeno-associated viral vector expressing Cre-dependent channelrhodopsin-2 fused to a V5 epitope and the ligand-binding domain of estrogen receptor (ChRERa) from a synapsin promoter, for use in PET

   Depositor

   Christopher Richie

   Article

   Bonaventura et al Sci Transl Med. 2023 Jul 26;15(706):eadd

   Insert

   hChR2(H134R)-V5-ER-LBD (ChRERa)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   SYN1

   Available since

   Oct. 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA

   Plasmid

   #20298

   Purpose

   Cre-activated AAV expression of humanized ChR2 with H134R mutation fused to EYFP for optogenetic activation

   Depositor

   Karl Deisseroth

   Has Service

   AAV PHP.eB, AAV Retrograde, AAV1, AAV5, and AAV9

   Insert

   channelrhodopsin-2
   

   Use

   AAV

   Tags

   EYFP

   Expression

   Mammalian

   Mutation

   humanized ChR2 gene with histidine 134 changed to…

   Promoter

   EF1alpha

   Available since

   May 13, 2009

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-EF1a-double floxed-hChR2(H134R)-mCherry-WPRE-HGHpA

   Plasmid

   #20297

   Purpose

   Cre-activated AAV expression of humanized ChR2 with H134R mutation fused to mCherry for optogenetic activation

   Depositor

   Karl Deisseroth

   Has Service

   AAV Retrograde, AAV1, AAV5, AAV8, and AAV9

   Insert

   channelrhodopsin-2
   

   Use

   AAV

   Tags

   mCherry

   Expression

   Mammalian

   Mutation

   humanized ChR2 gene with histidine 134 changed to…

   Promoter

   EF1alpha

   Available since

   June 23, 2009

   Availability

   Academic Institutions and Nonprofits only

   

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10. AAV phSyn1-FSF-FLEX-ChR2(H134R)-EYFP-WPRE-bGHpA

    Plasmid

    #65454

    Purpose

    Can be used to generate AAV virus that will express the ChR2(H134R)-EYFP channelrhodopsin fusion protein in neurons under intersectional control by Flp and Cre recombinases

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    EYFP

    Expression

    Mutation

    H134R variant

    Promoter

    hSyn1

    Available since

    July 7, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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11. AAV phSyn1-RSR-FLEX-ChR2(H134R)-EYFP-WPRE-bGHpA

    Plasmid

    #65429

    Purpose

    Can be used to generate AAV virus that will express the ChR2(H134R)-EYFP channelrhodopsin fusion protein in neurons under intersectional control by Dre and Cre recombinases

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    EYFP

    Expression

    Mutation

    H134R variant

    Promoter

    hSyn1

    Available since

    July 17, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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12. AiP14870 - pAAV-AiE0452h_3xC2-minBG-ChR2(H134R)-EYFP-WPRE3-BGHpA (Alias: CN4870)

    Plasmid

    #224186

    Purpose

    AiE0452h_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal D2 MSNs

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. AiP13278: pAAV-AiE0779m_3xC2-minBG-ChR2(CRC)-EYFP-WPRE3-BGHpA (Alias: CN3278)

    Plasmid

    #214843

    Purpose

    Expression of ChR2(L132C, H134R, T159C)-EYFP in striatal direct pathway medium spiny neurons (D1 MSNs)

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    ChR2(L132C, H134R, T159C)-EYFP
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. AiP13276: pAAV-AiE0779m_3xC2-minBG-ChR2(H134R)-EYFP-WPRE3-BGHpA (Alias: CN3276)

    Plasmid

    #214842

    Purpose

    Expression of ChR2(H134R)-EYFP in striatal direct pathway medium spiny neurons (D1 MSNs)

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. AiP13755: pAAV-AiE0743m_3xC2-minBG-ChR2(H134R)-EYFP-WPRE3-BGHpA (Alias: CN3755)

    Plasmid

    #214846

    Purpose

    Expression of ChR2(H134R)-EYFP in striatal cholinergic neurons

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Has Service

    AAV PHP.eB

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. AiP14823: pAAV-AiE0441h_3xC2-minBG-ChR2(H134R)-EYFP-WPRE3-BGHpA (Alias: CN4823)

    Plasmid

    #214860

    Purpose

    Expression of ChR2(H134R)-EYFP in striatal medium spiny neurons

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. AiP11763: pAAV-hEF1a-DIO-ChR2(CRC)-EYFP-WPRE-HGHpA (Alias: CN1763)

    Plasmid

    #236602

    Purpose

    A vector for Cre dependent expression of ChR2(CRC)-EYFP; CRC variant contains mutations L132C, H134R, and T159C in ChR2

    Depositor

    Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    ChR2(CRC)-EYFP
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. AiP12577 - pAAV-AiE0140h_3xC2-minBG-ChR2(CRC)-EYFP-WPRE3-BGHpA (Alias: CN2577)

    Plasmid

    #224166

    Purpose

    AiE0140h_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal Pvalb+ neurons

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    ChR2(CRC)-EYFP
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Sept. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pCL051 AAVS1-9xTetO-nTATAchr21-IGKleader-Cas9site-hIgG1_FC-Myc-PDGFRb-T2A-Citrine-PolyA

    Plasmid

    #188745

    Purpose

    Donor vector for integrating nonTATAchr21 promoter-driven dual surface marker/mCitrine fluorescent reporter at AAVS1 locus

    Depositor

    Lacra Bintu, Michael Bassik

    Article

    Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038

    Insert

    Surface marker and mCitrine reporter
    

    Use

    Synthetic Biology

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    nonTATAchr21

    Available since

    May 7, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV_BiPVe3_ChR2_mCherry (AAV PHP.eB)

    Viral Prep

    #213941-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiPVe3_ChR2_mCherry (#213941). In addition to the viral particles, you will also receive purified pAAV_BiPVe3_ChR2_mCherry plasmid DNA. Expression of mCherry-tagged channelrhodopsin-2 under the control of the PV+ basket cell-targeting enhancer E3. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Promoter

    Tags

    mCherry

    Available since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only