We narrowed to 43,508 results for: ANT

1. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

   Pooled Library

   #136478

   Purpose

   Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

   Depositor

   Jonathan Weissman

   Article

   Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

2. TP53 MITE Library

   Pooled Library

   #113569

   Purpose

   Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

   Depositor

   William Hahn, David Root

   Article

   Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

3. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

   Pooled Library

   #168776

   Purpose

   Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Species

   Sars-cov-2

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

4. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

   Pooled Library

   #168777

   Purpose

   Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Species

   Sars-cov-2

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

5. Human Base Editing Sensor Library

   Pooled Library

   #179218

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

6. Mouse Base Editing Sensor Library

   Pooled Library

   #179217

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

7. ALL-PAM sensor Library

   Pooled Library

   #179219

   Purpose

   10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

8. Barcode Library 0 (BCL0)

   Pooled Library

   #179851

   Purpose

   Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

   Depositor

   Jason Moffat

   Article

   Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 12, 2022

   Availability

   Academic Institutions and Nonprofits only

9. Barcode Library 1 (BCL1)

   Pooled Library

   #179852

   Purpose

   Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code CCAA.

   Depositor

   Jason Moffat

   Article

   Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 12, 2022

   Availability

   Academic Institutions and Nonprofits only

10. pDONR221_SLC25A4

    Plasmid

    #131982

    Purpose

    Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

    Insert

    SLC25A4 (SLC25A4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 22, 2019

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

11. pDONR221-SLC25A4_STOP

    Plasmid

    #161148

    Purpose

    Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

    Insert

    SLC25A4 (SLC25A4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    June 21, 2021

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

12. pEF2-FL-hTyro_gR1

    Plasmid

    #225995

    Purpose

    Expresses a chimeric contruct having N-terminal human Tyro3 and C-terminal human Interferon Gamma Receptor

    Depositor

    Raymond Birge, Sergei Kotenko

    Article

    Tsou et al J Biol Chem. 2014 Sep 12;289(37):25750-6

    Insert

    human Tyro3 N-Terminal human Interferon Gamma R1 Receptor C-Terminal fusion (TYRO3, IFNGR1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1-a

    Available since

    Nov. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pEF2-FL-hMer_gR1

    Plasmid

    #225993

    Purpose

    Expresses a chimeric contruct having N-terminal human MerTK and C-terminal human Interferon Gamma Receptor

    Depositor

    Raymond Birge, Sergei Kotenko

    Article

    Tsou et al J Biol Chem. 2014 Sep 12;289(37):25750-6

    Insert

    human MerTK N-Terminal human Interferon Gamma R1 Receptor C-Terminal fusion (MERTK, IFNGR1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1-a

    Available since

    Nov. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pEF2-FL-hAxl_gR1

    Plasmid

    #225994

    Purpose

    Expresses a chimeric contruct having N-terminal human Axl and C-terminal human Interferon Gamma Receptor

    Depositor

    Raymond Birge, Sergei Kotenko

    Article

    Tsou et al J Biol Chem. 2014 Sep 12;289(37):25750-6

    Insert

    human Axl N-Terminal human Interferon Gamma R1 Receptor C-Terminal fusion (AXL, IFNGR1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1-a

    Available since

    Nov. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pEF2-EFGR-hAxl

    Plasmid

    #225997

    Purpose

    Expresses a chimeric contruct having N-terminal human EGFR and C-terminal human Axl

    Depositor

    Raymond Birge, Sergei Kotenko

    Article

    Kimani et al Cell Commun Signal. 2016 Sep 6;14(1):19.

    Insert

    human EGFR N-Terminal human Axl C-Terminal Fusion (EGFR, AXL Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1-a

    Available since

    Nov. 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pEF2-EFGR-hTyro

    Plasmid

    #225998

    Purpose

    Expresses a chimeric construct having N-terminal human EGFR and C-terminal human Tyro3

    Depositor

    Raymond Birge, Sergei Kotenko

    Article

    Kimani et al Cell Commun Signal. 2016 Sep 6;14(1):19.

    Insert

    human EGFR N-Terminal human Tyro3 C-Terminal Fusion (EGFR, TYRO3 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1-a

    Available since

    Nov. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pEF2-EFGR-hMer

    Plasmid

    #225996

    Purpose

    Expresses a chimeric construct having N-terminal human EGFR and C-terminal human MerTK

    Depositor

    Raymond Birge, Sergei Kotenko

    Article

    Kimani et al Cell Commun Signal. 2016 Sep 6;14(1):19.

    Insert

    human EGFR N-Terminal human MerTK C-Terminal Fusion (EGFR, MERTK Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1-a

    Available since

    Nov. 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pEPIP_PepTile_40merFragments_65CancerDrivers

    Pooled Library

    #172109

    Purpose

    Lentiviral peptide expression library for overexpression fitness screening

    Depositor

    Prashant Mali

    Article

    Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

    Use

    Lentiviral

    Available since

    Oct. 21, 2021

    Availability

    Academic Institutions and Nonprofits only

19. pSMAL-CellTag-V1

    Pooled Library

    #115643

    Purpose

    Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Has Service

    Concentrated Lentiviral Prep

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Dec. 5, 2018

    Availability

    Academic Institutions and Nonprofits only

20. pSMAL-CellTag-V2

    Pooled Library

    #115644

    Purpose

    Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Has Service

    Concentrated Lentiviral Prep

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Dec. 5, 2018

    Availability

    Academic Institutions and Nonprofits only