We narrowed to 18,556 results for: MUT

1. pBABEpuro-gateway

   Plasmid

   #51070

   Purpose

   gateway adapted mammalian expression vector

   Depositor

   Matthew Meyerson

   Article

   Greulich et al Proc Natl Acad Sci U S A. 2012 Sep 4;109

   Type

   Empty backbone

   Use

   Retroviral

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   Feb. 25, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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2. ABE7.10-F148A

   Plasmid

   #132946

   Purpose

   Gene editing. See Gene/Insert section of plasmid page for targeting sequence cloned into this plasmid.

   Depositor

   Hui Yang

   Article

   Zhou et al Nature. 2019 Jul;571(7764):275-278. doi:

   Insert

   ABE7.10(F148A)
   

   Use

   CRISPR; Base editor

   Expression

   Mammalian

   Mutation

   ABE7.10(F148A)

   Available Since

   Dec. 1, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pMSCV-IRES-GFP/CALR wt-FLAG

   Plasmid

   #204525

   Purpose

   Retroviral expression of human CALR wt-FLAG

   Depositor

   Norio Komatsu

   Article

   Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

   Insert

   CALR wt-FLAG (CALR Human)
   

   Use

   Retroviral

   Available Since

   Dec. 13, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. Flag-Jun4A-Myc

   Plasmid

   #47444

   Purpose

   mammalian expression of mutant c-Jun (four N-terminal residues phosphorylated by JNK are mutated into Alanines)

   Depositor

   Axel Behrens

   Article

   Aguilera et al Nature. 2011 Jan 13;469(7329):231-5. doi

   Insert

   Jun 4A mutant (Jun Mouse)
   

   Tags

   Flag and myc

   Expression

   Mammalian

   Mutation

   four N-terminal residues phosphorylated by JNK, s…

   Promoter

   CMV

   Available Since

   Oct. 28, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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5. CaMKIV-DCTK75E

   Plasmid

   #126423

   Purpose

   A kinase-dead mutant of CaMK IV (C-terminal regulatory domains removed making the enzyme constitutively active)

   Depositor

   Douglas Black

   Article

   Xie et al Nature. 2001 Apr 19;410(6831):936-9. doi

   Insert

   calcium/calmodulin-dependent protein kinase IV kinase-dead mutant (CAMK4 Human)
   

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   changed lysine 75 to glutamic acid

   Available Since

   July 12, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. BE3-hA3A-R128A

   Plasmid

   #132944

   Purpose

   Gene editing. See Gene/Insert section of the plasmid page for targeting sequence cloned into this plasmid.

   Depositor

   Hui Yang

   Article

   Zhou et al Nature. 2019 Jul;571(7764):275-278. doi:

   Insert

   BE3-hA3A(R128A)
   

   Use

   CRISPR; Base editor

   Expression

   Mammalian

   Mutation

   BE3-hA3A(R128A)

   Available Since

   Nov. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. pESC-LEU-HsAIDSc

   Plasmid

   #60810

   Purpose

   to express human AID recoded for yeast codon usage

   Depositor

   Thomas Kunkel, Youri Pavlov

   Article

   Mayorov et al BMC Immunol. 2005 Jun 10;6:10.

   Insert

   AID (AICDA Human)
   

   Tags

   Myc

   Expression

   Yeast

   Mutation

   codon optimized for yeast

   Promoter

   GAL1

   Available Since

   Dec. 19, 2014

   Availability

   Academic Institutions and Nonprofits only

8. BE3-hA3A-Y130F

   Plasmid

   #132945

   Purpose

   Gene editing. See Gene/Insert section of plasmid page for targeting sequence cloned into this plasmid.

   Depositor

   Hui Yang

   Article

   Zhou et al Nature. 2019 Jul;571(7764):275-278. doi:

   Insert

   BE3-hA3A(Y130F)
   

   Use

   CRISPR; Base editor

   Expression

   Mammalian

   Mutation

   BE3-hA3A(Y130F)

   Available Since

   Nov. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pαH-S-HRV3C/D614G

   Plasmid

   #164568

   Purpose

   SARS-CoV-2 Spike protein with furin site mutated to HRV3C site and D614G mutation (S-HRV3C-D614G variant)

   Depositor

   Priyamvada Acharya

   Article

   Gobeil et al Cell Rep. 2021 Jan 12;34(2):108630. doi:

   Insert

   Spike (S-HRV3C-D614G variant)
   

   Tags

   2X Strep-Tag II and 8X His tag

   Expression

   Mammalian

   Mutation

   D614G

   Available Since

   Feb. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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10. pcDNA3.2-Cx43-NoStart

    Plasmid

    #49853

    Purpose

    Encodes human connexin 43 with the start methionine codon mutated to isoleucine and with wobble mutations conferring resistance against an siRNA

    Depositor

    Robin Shaw

    Article

    Smyth et al Cell Rep. 2013 Nov 5. pii: S2211-1247(13

    Insert

    Connexin 43 (GJA1 Human)
    

    Expression

    Mammalian

    Mutation

    Start codon mutated to from methionine to isoleuc…

    Promoter

    CMV

    Available Since

    Jan. 17, 2014

    Availability

    Academic Institutions and Nonprofits only

11. pCKC017

    Plasmid

    #226622

    Purpose

    pLenti wt hTdT template for libraries 1-2

    Depositor

    Chang Liu

    Article

    Carlson et al bioRxiv [Preprint]. 2024 Jun 11:2024.06.

    Insert

    Terminal deoxynucleotidyl transferase (DNTT Human)
    

    Use

    Lentiviral and Synthetic Biology

    Expression

    Mammalian

    Mutation

    synonymous mutation in D2, synonymous mutation in…

    Promoter

    CMV

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pWZL-hygro-FAKS732A/S910A

    Plasmid

    #221642

    Purpose

    This retroviral plasmid expresses a double-mutated cDNA (dominant negative: S732A/S910A) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (S732A/S910A) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK double mutation S732A/S910A (dominant negativ…

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pWZL-hygro-FAKP712/713A

    Plasmid

    #216544

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: P712/713A) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (P712/713A) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation P712/713A

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pWZL-hygro-FAKR177/178A

    Plasmid

    #216543

    Purpose

    This retroviral plasmid expresses a mutated cDNA (dominant negative: R177/178A) of human PTK2

    Depositor

    Georgia Konstantinidou

    Article

    Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

    Insert

    PTK2 (R177/178A) (PTK2 Human)
    

    Use

    Retroviral

    Tags

    No

    Expression

    Mammalian

    Mutation

    FAK dominant negative mutation R177/178A

    Available Since

    Sept. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLKO.3R/MPL-shRNA4

    Plasmid

    #204529

    Purpose

    Lentiviral expression of MPL-shRNA4; gene knock down of human MPL

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    MPL-shRNA4 (MPL Human)
    

    Use

    Lentiviral

    Available Since

    Sept. 12, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLKO.3R/MPL-shRNA3

    Plasmid

    #204528

    Purpose

    Lentiviral expression of MPL-shRNA3; gene knock down of human MPL

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    MPL-shRNA3 (MPL Human)
    

    Use

    Lentiviral

    Available Since

    Sept. 12, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pLKO.3R/MPL-shRNA2

    Plasmid

    #204527

    Purpose

    Lentiviral expression of MPL-shRNA2; gene knock down of human MPL

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    MPL-shRNA2 (MPL Human)
    

    Use

    Lentiviral

    Available Since

    Sept. 12, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLKO.3R/MPL-shRNA1

    Plasmid

    #204526

    Purpose

    Lentiviral expression of MPL-shRNA1; gene knock down of human MPL

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    MPL-shRNA1 (MPL Human)
    

    Use

    Lentiviral

    Available Since

    Sept. 12, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. pcDNA3.1/CALR ins5 (del1-17)-FLAG

    Plasmid

    #204533

    Purpose

    Mammalian expression of human CALR ins5 (del1-17)-FLAG

    Depositor

    Norio Komatsu

    Article

    Araki et al Blood. 2016 Jan 27. pii: blood-2015-09-6

    Insert

    CALR ins5 (del1-17)-FLAG (CALR Human)
    

    Expression

    Mammalian

    Mutation

    ins5 (del1-17)

    Available Since

    Sept. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAc5.1B-lambdaN-HA-DmTral-ADF_E

    Plasmid

    #146206

    Purpose

    Insect Expression of DmTral-ADF

    Depositor

    Elisa Izaurralde

    Article

    Tritschler et al Mol Cell. 2009 Mar 13. 33(5):661-8.

    Insert

    DmTral-ADF (tral Fly)
    

    Expression

    Insect

    Mutation

    three silent mutations A198C, A387G, A1437G and 4…

    Available Since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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