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pAAV-CAG-iRFP670-P2A-GFP

Plasmid

#197169

Purpose

Expresses the protein of iRFP670-P2A-GFP in mammalian cells

Depositor

Kiryl Piatkevich

Article

Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4

Insert

iRFP670-P2A-GFP

Use

AAV

Available Since

March 13, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-iRFP713-P2A-GFP

Plasmid

#197166

Purpose

Expresses the protein of iRFP713-P2A-GFP in mammalian cells

Depositor

Kiryl Piatkevich

Article

Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4

Insert

iRFP713-P2A-GFP

Use

AAV

Available Since

March 13, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-E2-Crimson-P2A-GFP

Plasmid

#197162

Purpose

Expresses the protein of E2-Crimson-P2A-GFP in mammalian cells

Depositor

Kiryl Piatkevich

Article

Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4

Insert

E2-Crimson-P2A-GFP

Use

AAV

Available Since

March 13, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-emiRFP703-P2A-GFP

Plasmid

#197158

Purpose

Expresses the protein of emiRFP703-P2A-GFP in mammalian cells

Depositor

Kiryl Piatkevich

Article

Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4

Insert

emiRFP703-P2A-GFP

Use

AAV

Available Since

March 13, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-IFP2-P2A-GFP

Plasmid

#197161

Purpose

Expresses the protein of IFP2-P2A-GFP in mammalian cells

Depositor

Kiryl Piatkevich

Article

Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4

Insert

IFP2-P2A-GFP

Use

AAV

Available Since

March 10, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-mRhubarb720-P2A-GFP

Plasmid

#197159

Purpose

Expresses the protein of mRhubarb720-P2A-GFP in mammalian cells

Depositor

Kiryl Piatkevich

Article

Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4

Insert

mRhubarb720-P2A-GFP

Use

AAV

Available Since

March 10, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-BDFP1.6-P2A-GFP

Plasmid

#197154

Purpose

Expresses the protein of BDFP1.6-P2A-GFP in mammalian cells

Depositor

Kiryl Piatkevich

Article

Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4

Insert

BDFP1.6-P2A-GFP

Use

AAV

Available Since

March 10, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-mRhubarb719-P2A-GFP

Plasmid

#197152

Purpose

Expresses the protein of mRhubarb719-P2A-GFP in mammalian cells

Depositor

Kiryl Piatkevich

Article

Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4

Insert

mRhubarb719-P2A-GFP

Use

AAV

Available Since

March 7, 2023

Availability

Academic Institutions and Nonprofits only

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AAV-Synapsin-mTurquoise-3XNLS-WPRE

Plasmid

#159949

Purpose

optical regulation of nuclear export

Depositor

Michael Courtney

Article

Li et al Nat Commun. 2020 Oct 9;11(1):5107. doi:

Insert

mTurquoise-3XNLS

Use

AAV

Expression

Mammalian

Mutation

synthetic

Promoter

hSyn1

Available Since

Oct. 23, 2020

Availability

Academic Institutions and Nonprofits only

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AAV-Synapsin-JNKKTR -miRFP670-WPRE

Plasmid

#159976

Purpose

single wavelength translocating reporter of the JNK pathway

Depositor

Michael Courtney

Article

Li et al Nat Commun. 2020 Oct 9;11(1):5107. doi:

Insert

JNKKTR -miRFP670

Use

AAV

Expression

Mammalian

Mutation

synthetic

Promoter

hSyn1

Available Since

Oct. 23, 2020

Availability

Academic Institutions and Nonprofits only

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pAAV-EF1a-DIO-FLAG-mouse Beta 2 Adrenergic Receptor (Adrb2)

Plasmid

#233041

Purpose

To Express a CRE dependent Flag tagged Mouse Beta 2 Adrenergic Receptor (Adrb2) from an EF1a promoter

Depositor

Jonathan Ploski

Insert

mouse Beta 2 Adrenergic Receptor (Adrb2 Mouse)

Use

AAV

Available Since

March 4, 2025

Availability

Academic Institutions and Nonprofits only

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AiP11969 - pAAV-hsA2-AiE0140h-minRho-SYFP2-4X2C-WPRE-HGHpA (Alias: CN1969)

Plasmid

#223969

Purpose

AiE0140h is an enhancer sequence, designed to drive AAV-mediated transgene expression in cortical Pvalb+ neurons

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Ben-Simon et al bioRxiv [Preprint]. 2024 Sep 26:2024.06.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

minBG

Available Since

Oct. 21, 2024

Availability

Academic Institutions and Nonprofits only

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AiP14532-pAAV-DLX2.0-minBG-FlpO-WPRE3-BGHpA (Alias: CN4532)

Plasmid

#222939

Purpose

FlpO recombinase expression from the DLX2.0 enhancer

Depositor

Jonathan Ting

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

FlpO (flp Synthetic)

Use

AAV

Available Since

Sept. 23, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-IgK-R-deLACCO1-COBRA

Plasmid

#223347

Purpose

Biosensor for extracellular L-lactate

Depositor

Marie-Eve Paquet

Article

Kamijo et al Nat Commun. 2025 Oct 29;16(1):9531. doi:

Insert

deLACCO1

Use

AAV

Tags

GPI-COBL9 Anchor

Available Since

Sept. 11, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-IgK-R-eLACCO2.1-COBRA

Plasmid

#223349

Purpose

Biosensor for extracellular L-lactate

Depositor

Marie-Eve Paquet

Article

Kamijo et al Nat Commun. 2025 Oct 29;16(1):9531. doi:

Insert

eLACCO2.1

Use

AAV

Tags

GPI-COBL9 Anchor

Available Since

Sept. 11, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-EFS-CasRx-P2A-mCherry-pA

Plasmid

#233025

Purpose

To Express HA tagged CasRX and mcherry from the mammalian EFS promoter. The CasRx and mCherry are separated by a P2A site

Depositor

Jonathan Ploski

Article

Back et al Mol Ther Methods Clin Dev. 2025 Aug 20;3

Insert

CasRx/mCherry

Use

AAV

Tags

mCherry

Available Since

March 4, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-Ef1a-Con/Fon-EYFP

Plasmid

#231926

Purpose

Cre-on/Flp-on EYFP under the Ef1a promoter

Depositor

Karl Deisseroth

Article

Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

Insert

eYFP with introns

Use

AAV

Promoter

Ef1a

Available Since

Jan. 22, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-Ef1a-Coff/Fon-EYFP

Plasmid

#231927

Purpose

Cre-off/Flp-on EYFP under the Ef1a promoter

Depositor

Karl Deisseroth

Article

Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

Insert

eYFP with introns

Use

AAV

Promoter

Ef1a

Available Since

Jan. 22, 2025

Availability

Academic Institutions and Nonprofits only

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pM155: pAAV.CMV-Cas13e (GenScript CO)-NT sgRNA

Plasmid

#203451

Purpose

Plasmid expressing active and codon optimised Cas13e with non-targeting gRNA

Depositor

Guei-Sheung Liu

Article

Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

Inserts

U6-non targeting (NT) sgRNA
Cas13e

Use

AAV

Tags

HA and NLS

Expression

Mammalian

Mutation

Codon optimised using GenScript tool

Promoter

CMV and U6

Available Since

Dec. 12, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-FLEX-ArgiNLS-EGFP

Plasmid

#220601

Purpose

Cre-dependent expression of a single-cell discriminating version of EGFP fluorescent protein

Depositor

Sam Golden

Article

Szelenyi et al Proc Natl Acad Sci U S A. 2024 Aug 6;121

Insert

EGFP

Use

AAV and Cre/Lox

Tags

ArgiNLS

Expression

Mammalian

Promoter

CAG

Available Since

July 31, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-CaMKIIa-hsChRmine-eYFP-WPRE

Plasmid

#183530

Purpose

Optogenetics

Depositor

Karl Deisseroth

Article

Kishi et al Cell. 2022 Feb 17;185(4):672-689.e23. do

Insert

hsChRmine-eYFP

Use

AAV

Mutation

H33R

Promoter

CaMKIIa

Available Since

May 18, 2022

Availability

Academic Institutions and Nonprofits only

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pAAV-hsyn-RiboL1-LifeCamp

Plasmid

#251728

Purpose

Expression of soma-targeted calcium lifetime sensor LifeCamp under hSyn promoter in pAAV backbone

Depositor

Bernardo Sabatini

Article

Lodder et al bioRxiv 2025.12.23.696288

Insert

RiboL1-LifeCamp

Use

AAV

Expression

Mammalian

Available Since

Feb. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-CMV-HyPerFLEX-Sec61b

Plasmid

#238940

Purpose

Mammalian expression of HyPerFLEX targeted to the cytosolic side of the endoplasmic reticulum membranes

Depositor

Vsevolod Belousov

Article

Potekhina et al Nat Chem Biol. 2025 Oct 16. doi: 10.1038

Insert

HyPerFLEX-Sec61b

Use

Adenoviral

Expression

Mammalian

Promoter

CMV

Available Since

Oct. 22, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-P3-IgKL-SpyCatcher003-GINKO2

Plasmid

#234544

Purpose

to express a potassium sensor tagged with SpyCatcher in the liver

Depositor

Hajime Hirase

Article

Vittani et al bioRxiv 2025.03.18.643859

Insert

IgKL-SpyCatcher003-GINKO2

Use

AAV

Mutation

None

Promoter

P3

Available Since

May 5, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-L7-6-DD-T6B-MUT-YFP

Plasmid

#235146

Purpose

Expresses the inducible mutant T6B peptide fused with DHFR and YFP under the Purkinje cell-specific L7-6 promoter

Depositor

Giordano Lippi

Article

Zolboot et al Neuron. 2025 Apr 1:S0896-6273(25)00181-3

Insert

DHFR-fused mutant T6B peptide

Use

AAV

Mutation

5 tryptophan residues of T6B-WT mutated

Promoter

L7-6

Available Since

April 23, 2025

Availability

Academic Institutions and Nonprofits only

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pAav-IQGAP1-PQS1-3xFLAG

Plasmid

#84885

Purpose

rAAV-based template for genome engineering of the IQGAP1 C-terminus containing PQS1 and 3xFLAG tags and a selection cassette

Depositor

Sven Eyckerman

Article

Vandemoortele et al Sci Rep. 2016 Jun 6;6:27220. doi: 10.103

Inserts

IQGAP1 genomic region HR1 (IQGAP1 Human)
IQGAP1 genomic region HR2

Use

AAV

Tags

PQS1 3xFLAG

Promoter

no

Available Since

Nov. 28, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
pAav-TP53-PQS1-3xFLAG

Plasmid

#84884

Purpose

rAAV-based template for genome engineering of the p53 C-terminus containing PQS1 and 3xFLAG tags and a selection cassette

Depositor

Sven Eyckerman

Article

Vandemoortele et al Sci Rep. 2016 Jun 6;6:27220. doi: 10.103

Inserts

TP53 genomic region HR1 (TP53 Human)
TP53 genomic region HR2

Use

AAV

Tags

PQS1 3xFLAG

Promoter

no and no

Available Since

Nov. 28, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP15820 - pAAV-AiE0873m_3xC2-minBG-RiboL1-jGCaMP8s-WPRE3-BGHpA (Alias: CN5820)

Plasmid

#224205

Purpose

AiE0873m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal cholinergic neurons

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

Insert

RiboL1-jGCaMP8s

Use

AAV

Available Since

Oct. 3, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAVLINK-3'-MTOR-FLAG-bGHpA

Plasmid

#244419

Purpose

3' AAVLINK plasmid for MTOR expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

MTOR (MTOR Human)

Use

AAV

Tags

FLAG

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAVLINKv1-pCALM1-Cre-3' AHDC1

Plasmid

#236673

Purpose

3' AAVLINK plasmid for AHDC1 expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

AHDC1 (AHDC1 Human)

Use

AAV and Cre/Lox

Tags

FLAG

Promoter

pCALM1

Available Since

June 23, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAVLINKv1-pCALM1-Cre-3' POGZ

Plasmid

#236647

Purpose

3' AAVLINK plasmid for POGZ expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

POGZ (POGZ Human)

Use

AAV

Tags

FLAG

Promoter

pCALM1

Available Since

June 23, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAVLINKv1-pCALM1-Cre-3' CDC42BPB

Plasmid

#236715

Purpose

3' AAVLINK plasmid for CDC42BPB expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

CDC42BPB (CDC42BPB Human)

Use

AAV and Cre/Lox

Tags

FLAG

Promoter

PCalm1

Available Since

June 23, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAVLINKv1-pCALM1-Cre-3' ROBO2

Plasmid

#236687

Purpose

3' AAVLINK plasmid for ROBO2 expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

ROBO2 (ROBO2 Human)

Use

AAV and Cre/Lox

Tags

FLAG

Promoter

pCALM1

Available Since

June 23, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAVLINKv1-pCALM1-Cre-3' IQGAP3

Plasmid

#236705

Purpose

3' AAVLINK plasmid for IQGAP3 expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

IQGAP3 (IQGAP3 Human)

Use

AAV and Cre/Lox

Tags

FLAG

Promoter

pCALM1

Available Since

June 23, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-EFS-DIO-GRAB_CRF1.0

Plasmid

#208662

Purpose

Expresses the genetically-encoded fluorescent corticotropin-releasing factor (CRF) sensor GRAB_CRF1.0 in a cre-dependent manner

Depositor

Yulong Li

Article

Wang et al Science. 2023 Nov 17;382(6672):eabq8173.

Insert

GPCR activation based corticotropin-releasing factor (CRF) sensor GRAB_CRF1.0

Use

AAV

Promoter

EFS

Available Since

Dec. 20, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-EFS-DIO-GRAB_CRFmut

Plasmid

#208663

Purpose

Expresses the genetically-encoded fluorescent corticotropin-releasing factor (CRF) control sensor GRAB_CRFmut in a cre-dependent manner

Depositor

Yulong Li

Article

Wang et al Science. 2023 Nov 17;382(6672):eabq8173.

Insert

GPCR activation based corticotropin-releasing factor (CRF) contorl sensor GRAB_CRFmut

Use

AAV

Promoter

EFS

Available Since

Oct. 30, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP12674 - pAAV-AiE0086h-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2674)

Plasmid

#230124

Purpose

AiE0086h is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Promoter

minBG

Available Since

Nov. 5, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP15256 - pAAV-AiE0664m_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN5256)

Plasmid

#229931

Purpose

AiE0664m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific brain cell types

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Available Since

Sept. 12, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP14703 - pAAV-AiE2135m-minBG-iCre(R297T)-BGHpA (Alias: CN4703)

Plasmid

#229925

Purpose

AiE2135m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific brain cell types

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

iCre(R297T)

Use

AAV

Available Since

Aug. 19, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
AiP15291 - pAAV-AiE0710m-minBG-iCre(R297T)-BGHpA (Alias: CN5291)

Plasmid

#230510

Purpose

AiE0710m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

iCre(R297T)

Use

AAV

Promoter

minBG

Available Since

June 3, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge

Showing: 5761 - 5800 of 8865 results

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