167,601 results

1. DRH031_ AAV-SIO-nEF-WT-THR

   Plasmid

   #225090

   Purpose

   Cre-dependent expression of wild-type thyroid receptor beta (THRB, human) in neurons driven by nEF promoter.

   Depositor

   Bernardo Sabatini

   Article

   Hochbaum et al Cell. 2024 Oct 3;187(20):5679-5697.e23.

   Insert

   DN-THRB (THRB Human)
   

   Use

   AAV

   Available Since

   Oct. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. DRH032_ AAV-SIO-nEF-DN-THR

   Plasmid

   #225091

   Purpose

   Cre-dependent expression of dominant-negative thyroid receptor beta (THRB, human) in neurons driven by nEF promoter.

   Depositor

   Bernardo Sabatini

   Article

   Hochbaum et al Cell. 2024 Oct 3;187(20):5679-5697.e23.

   Insert

   WT-THRB (THRB Human)
   

   Use

   AAV

   Available Since

   Oct. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCfb12620

   Plasmid

   #219928

   Purpose

   PrTPI with the overhangs for SapI restriction site can be insert into the base plasmid of TUNEYALI

   Depositor

   Irina Borodina

   Insert

   Promoter TPI
   

   Expression

   Yeast

   Available Since

   June 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. AAVS1-iPE2-Hygro

   Plasmid

   #214019

   Purpose

   inducible PE2 system for controllable prime editing; this plasmid is used to insert PE2 prime editor in one allele of AAVS1 locus

   Depositor

   Ting Zhou

   Article

   Wu et al Nat Commun. 2024 Dec 30;15(1):10824. doi

   Insert

   PE2
   

   Expression

   Mammalian

   Promoter

   TRE-tight

   Available Since

   June 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pC3.1_CMV_oROS-G_LF(C199S)

   Plasmid

   #216112

   Purpose

   Expresses the loss-of-function mutations C199S of the genetically encoded green fluorescent hydrogen peroxide sensor oROS-G in mamalian cells.

   Depositor

   Andre Berndt

   Article

   Lee et al bioRxiv 2024.01.31.578117

   Insert

   oROS-G_LF(C199S)
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   May 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pC3.1_CAG_oROS-Gr_LF(C199S)

   Plasmid

   #216114

   Purpose

   Expresses the loss-of-function version of the genetically encoded, ratiometric hydrogen peroxide sensor oROS-Gr in mamalian cells.

   Depositor

   Andre Berndt

   Article

   Lee et al bioRxiv 2024.01.31.578117

   Insert

   oROS-Gr_LF(C199S)
   

   Expression

   Mammalian

   Promoter

   CAG

   Available Since

   April 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCDNA3-SREBP-1 (A317-318)

   Plasmid

   #204193

   Purpose

   Mammalian expression of SREBP-1 (isoform 1)

   Depositor

   Allan Weissman

   Article

   Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

   Insert

   SREBP-1 (SREBF1 Human)
   

   Tags

   E-tag and T7x2

   Expression

   Mammalian

   Mutation

   Gly to Ala 317, 318

   Available Since

   April 8, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCDNA3-SREBP-1 (A317-318; A341)

   Plasmid

   #204194

   Purpose

   Mammalian expression of SREBP-1 (Isoform 1)

   Depositor

   Allan Weissman

   Article

   Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

   Insert

   SREBP-1 (SREBF1 Human)
   

   Tags

   E-tag and T7x2

   Expression

   Mammalian

   Mutation

   Gly to Ala 317,318,341

   Available Since

   April 8, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pmax-PUFc_NES-ADARdd(E488Q)

   Plasmid

   #196837

   Purpose

   Express PUFc_NES-ADARdd(E488Q)

   Depositor

   Albert Cheng

   Article

   Liu et al Nucleic Acids Res. 2023 Aug 11;51(14):e7

   Insert

   PUFc_NES-ADARdd(E488Q)
   

   Expression

   Mammalian

   Available Since

   March 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pKLV2-U6gRNA5(RUNX1T1 g3)-PGKpuroBFP-W

    Plasmid

    #211984

    Purpose

    Express gRNA against RUNX1T1 with puro and BFP

    Depositor

    Kosuke Yusa

    Article

    Ishikawa et al Commun Biol. 2023 Dec 28;6(1):1290. doi:

    Insert

    sgRNA targeting RUNX1T1 (RUNX1T1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    Human U6 promoter

    Available Since

    Jan. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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