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pSicoR-RPL30i2

Plasmid

#59627

Purpose

Expression of shRNA against human RPL30

Depositor

Miguel Ramalho-Santos

Article

Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

Insert

RPL30 (RPL30 Human)

Use

RNAi

Expression

Mammalian

Promoter

U6

Available Since

Sept. 29, 2014

Availability

Academic Institutions and Nonprofits only
pSicoR-ARSDi2

Plasmid

#59601

Purpose

Expression of shRNA against human ARSD

Depositor

Miguel Ramalho-Santos

Article

Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

Insert

ARSD (ARSD Human)

Use

RNAi

Expression

Mammalian

Promoter

U6

Available Since

Sept. 26, 2014

Availability

Academic Institutions and Nonprofits only
pSicoR-UBE2E3i2

Plasmid

#59592

Purpose

Expression of shRNA against human UBE2E3

Depositor

Miguel Ramalho-Santos

Article

Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

Insert

UBE2E3 (UBE2E3 Human)

Use

RNAi

Expression

Mammalian

Promoter

U6

Available Since

Sept. 26, 2014

Availability

Academic Institutions and Nonprofits only
pSicoR-UBE2E3i1

Plasmid

#59590

Purpose

Expression of shRNA against human UBE2E3

Depositor

Miguel Ramalho-Santos

Article

Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

Insert

UBE2E3 (UBE2E3 Human)

Use

RNAi

Expression

Mammalian

Promoter

U6

Available Since

Sept. 26, 2014

Availability

Academic Institutions and Nonprofits only
pSicoR-UBE2D3i2

Plasmid

#59589

Purpose

Expression of shRNA against human UBE2D3

Depositor

Miguel Ramalho-Santos

Article

Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

Insert

UBE2D3 (UBE2D3 Human)

Use

RNAi

Expression

Mammalian

Promoter

U6

Available Since

Sept. 26, 2014

Availability

Academic Institutions and Nonprofits only
PU.1-delta75-100 LZRS

Plasmid

#44634

Depositor

Ellen Rothenberg

Article

Dionne et al Dev Biol. 2005 Apr 15;280(2):448-66.

Insert

PU.1 Δ75-100 (Spi1 Mouse)

Use

Retroviral

Tags

EGFP and IRES

Expression

Mammalian

Mutation

deletion of aa 75-100

Available Since

Oct. 24, 2013

Availability

Academic Institutions and Nonprofits only
PCx35-pcDNA-S110A

Plasmid

#42917

Depositor

John O'Brien

Article

Ouyang et al Brain Res Mol Brain Res. 2005 Apr 27;135

Insert

Connexin 35

Expression

Mammalian

Mutation

Ser110 to Ala

Promoter

CMV

Available Since

March 28, 2013

Availability

Academic Institutions and Nonprofits only

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PCx35CT-S298ter

Plasmid

#42913

Depositor

John O'Brien

Article

Ouyang et al Brain Res Mol Brain Res. 2005 Apr 27;135

Insert

Connexin 35 C-terminal domain

Tags

6x His, GST, and S-tag

Expression

Bacterial

Mutation

Ser298 stop codon

Promoter

T7

Available Since

March 26, 2013

Availability

Academic Institutions and Nonprofits only

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PCx35-pcDNA-S298ter

Plasmid

#42925

Depositor

John O'Brien

Article

Ouyang et al Brain Res Mol Brain Res. 2005 Apr 27;135

Insert

Connexin 35

Expression

Mammalian

Mutation

Ser298 to stop codon

Promoter

CMV

Available Since

March 26, 2013

Availability

Academic Institutions and Nonprofits only

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PCx35CT-S276A

Plasmid

#42912

Depositor

John O'Brien

Article

Ouyang et al Brain Res Mol Brain Res. 2005 Apr 27;135

Insert

Connexin 35 C-terminal domain

Tags

6x His, GST, and S-tag

Expression

Bacterial

Mutation

Ser276 to Ala

Promoter

T7

Available Since

March 26, 2013

Availability

Academic Institutions and Nonprofits only

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AiP12845 - pAAV-AiE0641m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2845)

Plasmid

#208158

Purpose

AiE0641m is an enhancer sequence designed to drive AAV-mediated transgene expression in brain oligodendrocytes

Depositor

Allen Institute for Brain Science, Jonathan Ting

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2

Use

AAV

Mutation

NA

Promoter

Beta Globin minimal promoter

Available Since

Oct. 23, 2023

Availability

Academic Institutions and Nonprofits only

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AiP13613 - pAAV-AiE1021h-minBG-SYFP2-P2A-3XFLAG-10aa-H2B-WPRE3-BGHpA (Alias: CN3613)

Plasmid

#230158

Purpose

AiE1021h is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Depositor

Allen Institute for Brain Science, Boaz Levi

Article

Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

Insert

SYFP2-P2A-3XFLAG-10aa-H2B

Use

AAV

Promoter

minBG

Available Since

Feb. 20, 2025

Availability

Academic Institutions and Nonprofits only

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pRN227

Plasmid

#127222

Purpose

BeYDV replicon with 35S::Cas9, WUS2 and AtSTM, sgRNA targeting PDS

Depositor

Daniel Voytas

Article

Maher et al Nat Biotechnol. 2019 Dec 16. pii: 10.103

Insert

Cas9, WUS2, AtSTM, sgRNA

Expression

Plant

Mutation

codon optimized CDSs

Available Since

Dec. 17, 2019

Availability

Academic Institutions and Nonprofits only

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pcDNA3-ALK5 wt

Plasmid

#80876

Purpose

mammalian expression of ALK5 WT

Depositor

Aristidis Moustakas

Article

Moren et al J Biol Chem. 2005 Jun 10;280(23):22115-2

Insert

ALK5 (TGFBR1 Human)

Tags

HA

Expression

Mammalian

Promoter

CMV

Available Since

Aug. 25, 2016

Availability

Academic Institutions and Nonprofits only

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p4053 HA-E6AP isoform I

Plasmid

#8657

Depositor

Peter Howley

Article

Kao et al J Virol 2000 Jul;74(14):6408-17.

Insert

E6-AP isoform I (UBE3A Human)

Tags

HA

Expression

Mammalian

Promoter

CMV

Available Since

June 16, 2005

Availability

Academic Institutions and Nonprofits only

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pAAV-pCAG-FRT(F3F5)-ChRmine3.3-p2A-oScarlet,rev.-WPRE

Plasmid

#234895

Purpose

CAG-driven, Flp-dependent ChRmine for optogenetic excitation of neurons with an oScarlet tag

Depositor

Silvia Arber

Article

Falasconi et al Nature. 2025 May 28. doi: 10.1038/s41586

Insert

FRT(F3F5)-ChRmine3.3-p2A-oScarlet

Use

AAV

Available Since

June 5, 2025

Availability

Academic Institutions and Nonprofits only

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OpenCRISPR-1

Plasmid

#221565

Purpose

Express OpenCRISPR-1 nuclease in human cells using a CMV promoter

Depositor

Ali Madani

Article

Ruffolo et al Nature. 2025 Jul 30. doi: 10.1038/s41586

Insert

OpenCRISPR-1

Tags

NLS

Expression

Mammalian

Promoter

CMV

Available Since

Aug. 28, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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pAR-Ec633

Plasmid

#130873

Purpose

A nuclear plasmid encoding an error-prone mutant TP-DNAP1 (L477V, L640Y, I777K, W814N) for OrthoRep

Depositor

Chang Liu

Article

Ravikumar et al Cell. 2018 Dec 13;175(7):1946-1957.e13.

Insert

TP-DNAP1

Expression

Yeast

Mutation

L477V, L640Y, I777K, W814N

Available Since

Aug. 21, 2019

Availability

Academic Institutions and Nonprofits only

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VRQR-ABEmax

Plasmid

#119811

Purpose

A-to-G base editor

Depositor

David Liu

Article

Huang et al Nat Biotechnol. 2019 May 20. pii: 10.103

Insert

ecTadA-ecTadA*(7.10)-nSpCas9 (VRQR)

Expression

Mammalian

Available Since

May 22, 2019

Availability

Academic Institutions and Nonprofits only

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SaKKH-ABEmax

Plasmid

#119815

Purpose

A-to-G base editor

Depositor

David Liu

Article

Huang et al Nat Biotechnol. 2019 May 20. pii: 10.103

Insert

ecTadA-ecTadA*(7.10)-nSaCas9 (KKH)

Expression

Mammalian

Available Since

May 22, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge