We narrowed to 10,398 results for: 158

1. pCAG-hMbCas12a-NLS(nucleoplasmin)-3xHA (AAS2134)

   Plasmid

   #114090

   Purpose

   CAG promoter expression plasmid for human codon optimized MbCas12a nuclease with C-terminal NLS and HA tag

   Depositor

   Keith Joung, Benjamin Kleinstiver

   Article

   Kleinstiver et al Nat Biotechnol. 2019 Feb 11. pii: 10.103

   Insert

   human codon optimized MbCas12a
   

   Use

   Tags

   NLS(nucleoplasmin) and 3xHA

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Dec. 10, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pTR-471 IRF4-tNGFR

   Plasmid

   #186061

   Purpose

   Knockin of truncated NGFR to target gene

   Depositor

   Alexander Marson

   Article

   Shy et al Nat Biotechnol. 2022 Aug 25:10.1038/s415

   Insert

   IRF4 (IRF4 Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   WT with tNGFR sequence

   Promoter

   Available since

   July 28, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. p21-S208C/S242R/M694V-MEFV

   Plasmid

   #134706

   Purpose

   Lentiviral expression of human MEFV S208C/S242R/M694V after doxycycline administration

   Depositor

   Thomas Henry

   Article

   Magnotti et al EMBO Mol Med. 2019 Oct 7:e10547. doi: 10

   Insert

   MEFV (MEFV Human)
   

   Use

   Lentiviral

   Tags

   3xFlag

   Expression

   Mutation

   p.S208C/S242R/M694V

   Promoter

   TRE2 (Dox-inducible)

   Available since

   Dec. 10, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. pSN33

   Plasmid

   #100118

   Purpose

   expresses a chimeric KLF4-repressor fusion

   Depositor

   Mark Ptashne

   Article

   Narayan et al Cell Rep. 2017 Aug 15;20(7):1585-1596. d

   Insert

   mCherry-P2A-KLF4 fused to full length HP1 alpha (KLF4, CBX5 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Sept. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. HIPK2 gRNA (BRDN0001162222)

   Plasmid

   #76750

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human HIPK2

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   HIPK2 (HIPK2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. MSCV-BRD9_BRG1BD-PGK-Puro-IRES-GFP

   Plasmid

   #75121

   Purpose

   Retroviral expression plasmid encoding a human BRD9 bromodomain-swap mutant containing the BRG1 bromodomain

   Depositor

   Christopher Vakoc

   Article

   Hohmann et al Nat Chem Biol. 2016 Jul 4. doi: 10.1038/

   Insert

   BRD9 (BRD9 Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mutation

   Bromodomain replaced with the bromodomain of BRG1

   Promoter

   Available since

   June 30, 2016

   Availability

   Academic Institutions and Nonprofits only

7. MSCV-BRD9_BRD1BD-PGK-Puro-IRES-GFP

   Plasmid

   #75119

   Purpose

   Retroviral expression plasmid encoding a human BRD9 bromodomain-swap mutant containing the BRD1 bromodomain

   Depositor

   Christopher Vakoc

   Article

   Hohmann et al Nat Chem Biol. 2016 Jul 4. doi: 10.1038/

   Insert

   BRD9 (BRD9 Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mutation

   Bromodomain replaced with the bromodomain of BRD1

   Promoter

   Available since

   May 18, 2016

   Availability

   Academic Institutions and Nonprofits only

8. DTYMK gRNA (BRDN0001145924)

   Plasmid

   #77513

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human DTYMK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   DTYMK (DTYMK Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. CDK10 gRNA (BRDN0001145808)

   Plasmid

   #77578

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDK10

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDK10 (CDK10 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. CDK10 gRNA (BRDN0001149446)

    Plasmid

    #77579

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK10

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK10 (CDK10 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. MAP3K12 gRNA (BRDN0001144753)

    Plasmid

    #76760

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAP3K12

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAP3K12 (MAP3K12 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. MAP3K12 gRNA (BRDN0001147643)

    Plasmid

    #76761

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAP3K12

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAP3K12 (MAP3K12 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. MAP3K12 gRNA (BRDN0001147398)

    Plasmid

    #76762

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAP3K12

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAP3K12 (MAP3K12 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pAAV-CaMKII-Archon1-KGC-EGFP

    Plasmid

    #108418

    Purpose

    AAV production plasmid encoding for Archon1 fluorescent voltage reporter

    Depositor

    Edward Boyden

    Article

    Piatkevich et al Nat Chem Biol. 2018 Feb 26. pii: 10.1038

    Insert

    Archon1-KGC-EGFP
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CaMKII

    Available since

    June 6, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. TTK gRNA (BRDN0001145152)

    Plasmid

    #75579

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TTK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TTK (TTK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. TTK gRNA (BRDN0001146504)

    Plasmid

    #75580

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TTK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TTK (TTK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. TTK gRNA (BRDN0001147779)

    Plasmid

    #75581

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TTK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TTK (TTK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. DTYMK gRNA (BRDN0001147404)

    Plasmid

    #77511

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DTYMK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DTYMK (DTYMK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. DTYMK gRNA (BRDN0001148632)

    Plasmid

    #77512

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DTYMK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DTYMK (DTYMK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. HSPB8 gRNA (BRDN0001145453)

    Plasmid

    #75640

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human HSPB8

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    HSPB8 (HSPB8 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. HSPB8 gRNA (BRDN0001146985)

    Plasmid

    #75641

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human HSPB8

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    HSPB8 (HSPB8 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. HSPB8 gRNA (BRDN0001147486)

    Plasmid

    #75642

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human HSPB8

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    HSPB8 (HSPB8 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pCMV-FLAG-CHD5-Y619E-FRAG

    Plasmid

    #68871

    Purpose

    Mammalian expression of CHD5 histone binding domain (331-672aa) with Y619 mutation

    Depositor

    Adrian Bracken

    Article

    Egan et al Dev Cell. 2013 Aug 12;26(3):223-36. doi:

    Insert

    CHD5 (CHD5 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    331-672aa, Y619E

    Promoter

    CMV

    Available since

    Nov. 20, 2015

    Availability

    Academic Institutions and Nonprofits only

24. NC12 pCDNA3.1 VENUS WTX delta ETGE

    Plasmid

    #36967

    Depositor

    Randall Moon

    Article

    Camp et al J Biol Chem. 2012 Feb 24;287(9):6539-50.

    Insert

    WTX (delta ETGE motif) (AMER1 Human)
    

    Use

    Tags

    Venus

    Expression

    Mammalian

    Mutation

    lacks amino acids 288 –291

    Promoter

    CMV

    Available since

    July 24, 2012

    Availability

    Academic Institutions and Nonprofits only

25. pX458_mCherry-HP1a-gRNA-2

    Plasmid

    #237635

    Purpose

    Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    HP1a gRNA (CBX5 Human)
    

    Use

    CRISPR

    Tags

    mCherry

    Expression

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pRK5_mEGFP-SS18-SSX1-KS

    Plasmid

    #237679

    Purpose

    For overexpression of mEGFP-SS18-SSX1-KS

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    SS18-SSX1-KS (SS18, SSX1 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pRK5_mEGFP-SS18-SSX1

    Plasmid

    #237678

    Purpose

    For overexpression of mEGFP-SS18-SSX1

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    SS18-SSX1 (SS18, SSX1 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pRK5_mEGFP-SS18-SSX2-KS

    Plasmid

    #237680

    Purpose

    For overexpression of mEGFP-SS18-SSX2-KS

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    SS18-SSX2-KS (SS18, SSX2 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pX458_mCherry-HP1a-gRNA-1

    Plasmid

    #237634

    Purpose

    Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    HP1a gRNA (CBX5 Human)
    

    Use

    CRISPR

    Tags

    mCherry

    Expression

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pX458_mCherry-TCOF1-gRNA

    Plasmid

    #237633

    Purpose

    Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to TCOF1 locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    TCOF1 gRNA (TCOF1 Human)
    

    Use

    CRISPR

    Tags

    mCherry

    Expression

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge