We narrowed to 119 results for: mutant p53

1. pIVT-p53DD

   Plasmid

   #232751

   Purpose

   IVT template for making modRNA encoding p53DD, a mutant p53 that lacks DNA binding ability

   Depositor

   Kate Galloway

   Article

   Blanch-Asensio et al bioRxiv [Preprint]. 2024 Oct 17:2024.10.

   Insert

   p53DD
   

   Use

   In vitro transcription

   Tags

   Expression

   Mutation

   deletion of DNA binding domain

   Promoter

   Available since

   March 17, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAc-HT-Dmp53KRKR

   Plasmid

   #85699

   Purpose

   expression of Drosophila p53 KRKR mutant in Drosophila cells

   Depositor

   Licio Collavin, Giannino Del Sal

   Article

   Mauri et al J Biol Chem. 2008 Jul 25. 283(30):20848-

   Insert

   Dmp53 (p53 Fly)
   

   Use

   Tags

   His

   Expression

   Insect

   Mutation

   K26R K302R

   Promoter

   Ac5

   Available since

   March 21, 2017

   Availability

   Academic Institutions and Nonprofits only

3. pcDNA3 p53 S15D

   Plasmid

   #69005

   Purpose

   mammalian expression of human p53 S15D mutant

   Depositor

   David Meek

   Article

   Loughery et al Nucleic Acids Res. 2014 Jul;42(12):7666-

   Insert

   p53 (TP53 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   S15D

   Promoter

   CMV

   Available since

   Oct. 9, 2015

   Availability

   Academic Institutions and Nonprofits only

4. pcDNA3 p53 S15A

   Plasmid

   #69004

   Purpose

   mammalian expression of human p53 S15A mutant.

   Depositor

   David Meek

   Article

   Loughery et al Nucleic Acids Res. 2014 Jul;42(12):7666-

   Insert

   p53 (TP53 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   S15A

   Promoter

   CMV

   Available since

   Oct. 9, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCI-Neo-p53mut

   Plasmid

   #99239

   Purpose

   Mutant p53 encoded by AS-30D rat hepatoma cell line

   Depositor

   Peter Pedersen

   Article

   Mathupala et al J Biol Chem. 1997 Sep 5;272(36):22776-80

   Insert

   p53 (Tp53 Rat)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Silent mutations in translated protein at Gly (10…

   Promoter

   CMV immediate/early enhancer/promoter

   Available since

   Aug. 30, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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6. T7-p53DD-pcDNA3

   Plasmid

   #25989

   Depositor

   William Kaelin

   Article

   Irwin et al Nature. 2000 Oct 5. 407(6804):645-8.

   Insert

   tumor protein p53 (TP53 Human)
   

   Use

   Tags

   T7

   Expression

   Mammalian

   Mutation

   truncated cDNA encodes truncated protein (aa 300-…

   Promoter

   Available since

   Oct. 21, 2010

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV2-sgTrp53-sgAtrx-EFS-Cre

   Plasmid

   #189977

   Purpose

   Expresses Cre cDNA and sgRNAs targeting murine Trp53 and Atrx

   Depositor

   William Kaelin

   Article

   Shi et al Cancer Cell. 2022 Sep 12;40(9):939-956.e

   Insert

   sgTrp53, sgAtrx, Cre recombinase
   

   Use

   AAV, Cre/Lox, and Mouse Targeting

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Dec. 12, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. pBABE-hygro p53 DD

   Plasmid

   #9058

   Depositor

   Bob Weinberg

   Article

   Hahn et al Mol Cell Biol 2002 Apr;22(7):2111-23.

   Insert

   p53 DD (Trp53 Mouse)
   

   Use

   Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   DD. Dominant negative mutant carries deletion of…

   Promoter

   Available since

   Dec. 7, 2005

   Availability

   Academic Institutions and Nonprofits only

   

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9. NSK021 CMV-TO-p53R248Q (FLP-IN)

   Plasmid

   #191167

   Purpose

   Expression of human p53 mutant R248Q in mammalian cells

   Depositor

   Xiaojing Gao

   Article

   Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

   Insert

   p53(R248Q) (TP53 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   R248Q

   Promoter

   CMV-TO

   Available since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. NSK026 CMV-TO-p53R248W (FLP-IN)

    Plasmid

    #191168

    Purpose

    Expression of human p53 mutant R248W in mammalian cells

    Depositor

    Xiaojing Gao

    Article

    Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

    Insert

    p53(R248W) (TP53 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    R248W

    Promoter

    CMV-TO

    Available since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. BDS-2 3x MUT (p53 binding site)

    Plasmid

    #16516

    Depositor

    Bert Vogelstein

    Article

    Hermeking et al Mol Cell. 1997 Dec . 1(1):3-11.

    Insert

    p53 binding site (SFN Human)
    

    Use

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    Mutant p53 binding sites

    Promoter

    Available since

    March 28, 2008

    Availability

    Academic Institutions and Nonprofits only

12. pRRLNeo-pEF1a-p53ashL344A-mCerulean

    Plasmid

    #69580

    Purpose

    Expresses p53-L344A mutant tagged with mCerulean

    Depositor

    Galit Lahav

    Article

    Gaglia et al Proc Natl Acad Sci U S A. 2013 Sep 17;11

    Insert

    p53-L344A (TP53 Human)
    

    Use

    Lentiviral

    Tags

    mCerulean

    Expression

    Mammalian

    Mutation

    p53 L344A mutation that prevents tetramerization …

    Promoter

    EF1alpha

    Available since

    Feb. 22, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pRRLNeo-pEF1a-p53ashL344P-mCerulean

    Plasmid

    #69581

    Purpose

    Expresses p53-L344P mutant tagged with mCerulean

    Depositor

    Galit Lahav

    Article

    Gaglia et al Proc Natl Acad Sci U S A. 2013 Sep 17;11

    Insert

    p53-L344P (TP53 Human)
    

    Use

    Lentiviral

    Tags

    mCerulean

    Expression

    Mammalian

    Mutation

    p53 L344P mutation that prevents oliogomerization…

    Promoter

    EF1alpha

    Available since

    Feb. 22, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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14. pRetroX-TRE3G-IRSp53 P428L

    Plasmid

    #221321

    Purpose

    Dox-inducible expression of IRSp53 mutant in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG

    Expression

    Mutation

    P428L

    Promoter

    TRE3G

    Available since

    July 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pRetroX-TRE3G-IRSp53 S269D

    Plasmid

    #221319

    Purpose

    Dox-inducible expression of IRSp53 mutant in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG

    Expression

    Mutation

    S269D

    Promoter

    TRE3G

    Available since

    July 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCMV-Neo-Bam p53 V143A

    Plasmid

    #16435

    Depositor

    Bert Vogelstein

    Article

    Baker et al Science. 1990 Aug 24. 249(4971):912-5.

    Insert

    p53 V143A (TP53 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    V143A. Mutant cDNA from human colorectal tumor CX…

    Promoter

    Available since

    March 12, 2008

    Availability

    Academic Institutions and Nonprofits only

17. pcDNA3.1-3XHA-p53 QM

    Plasmid

    #196268

    Purpose

    Mammalian expression of 3xHA tagged p53 L25Q,Q26S,F53Q,F54S

    Depositor

    Laura Attardi

    Article

    Raj et al Mol Cell. 2022 Jul 7;82(13):2370-2384.e1

    Insert

    Trp53 QM (Trp53 Mouse)
    

    Use

    Tags

    3xHA

    Expression

    Mammalian

    Mutation

    p53 L25Q,Q26S,F53Q,F54S mutant

    Promoter

    CMV

    Available since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. NSK024 SFFV-mCherry-SG(p53R248Q.s2)SG-EGFP (FLP-IN)

    Plasmid

    #191169

    Purpose

    Expression of a sensor for p53 mutant R248Q in mammalian cells; mCherry marker, EGFP output

    Depositor

    Xiaojing Gao

    Article

    Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

    Insert

    mCherry:p53(R248Q).s2:EGFP
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    SFFV

    Available since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pGLS3-5xHRE-p53(K164R)

    Plasmid

    #72555

    Purpose

    Hypoxia induced mutant p53. Contains the HRE from VEGF sequence (5 repeats) upstream of p53 K164R.

    Depositor

    Ester Hammond

    Article

    Leszczynska et al J Clin Invest. 2015 Jun;125(6):2385-98.

    Insert

    p53 (TP53 Human)
    

    Use

    Tags

    5XHRE

    Expression

    Mammalian

    Mutation

    K164R

    Promoter

    E1B minimal promoter

    Available since

    March 9, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pGLS3-5xHRE-p53(K120R)

    Plasmid

    #72554

    Purpose

    Hypoxia induced mutant p53. Contains the HRE from VEGF sequence (5 repeats) upstream of p53 K120R.

    Depositor

    Ester Hammond

    Article

    Leszczynska et al J Clin Invest. 2015 Jun;125(6):2385-98.

    Insert

    p53 (TP53 Human)
    

    Use

    Tags

    5XHRE

    Expression

    Mammalian

    Mutation

    K120R

    Promoter

    E1B minimal promoter

    Available since

    April 12, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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