We narrowed to 8,698 results for: PAC;

1. pAAV-SCP1-dSa VPR mini.-2X snRP-1 Actc1

   Plasmid

   #99690

   Purpose

   Expresses dSa Cas9 fused to optimized combination of truncated activation domains from SCP1 promoter with dual snRP1 poly adenylation signal, and Sa sgRNA for Actc1, vector allows for strong activation of mouse Actc1, can be packaged and delivered as AAV

   Depositor

   George Church

   Article

   Vora et al bioRxiv 2018. 298620

   Insert

   dCas9 and gRNA targeting Actc1 (gRNA sequence: GCCATTCTTGGAGCCAAGGG ) (Actc1 Mouse, Synthetic)
   

   Use

   AAV and CRISPR

   Tags

   VPR mini

   Expression

   Mutation

   dead Cas9

   Promoter

   Available since

   Sept. 12, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pAAV-SCP1-dSa VPR mini.-2X snRP-1 Neurog2

   Plasmid

   #99694

   Purpose

   Expresses dSa Cas9 fused to optimized combination of truncated activation domains from SCP1 promoter with dual snRP1 poly adenylation signal, and Sa sgRNA for Actc1, vector allows for strong activation of mouse Actc1, can be packaged and delivered as AAV

   Depositor

   George Church

   Article

   Vora et al bioRxiv 2018. 298620

   Insert

   dCas9 and gRNA targeting Actc1 (gRNA: GGTATATAAGGGGTTTTAAG) (Actc1 Mouse, Synthetic)
   

   Use

   AAV and CRISPR

   Tags

   VPR mini

   Expression

   Mutation

   dead Cas9

   Promoter

   Available since

   Jan. 16, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pLJM5-mSHMT2

   Plasmid

   #83905

   Purpose

   stable overexpression

   Depositor

   David Sabatini

   Article

   Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

   Insert

   Serine hydroxymethyltransferase 2 (Shmt2 Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Oct. 21, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pET30-2-PSPH

   Plasmid

   #83909

   Purpose

   stable overexpression

   Depositor

   David Sabatini

   Article

   Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

   Insert

   phosphoserine phosphatase (PSPH Human)
   

   Use

   Tags

   6x His tags

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   Oct. 21, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pcDNA3.1(-).TagRFP.T-2A-V5-8D2Q.Tau2N4R-WPRE

   Plasmid

   #226382

   Purpose

   Expresses tau propagation ORF with V5 tag on 8D2Q mutant 2N4R tau

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   TagRFP.T.2A.V5

   Expression

   Mammalian

   Mutation

   8D2Q.Tau2N4R

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pcDNA3.1(-).TagRFP.T-2A-V5-20D3Q.Tau2N4R-WPRE

   Plasmid

   #226383

   Purpose

   Expresses tau propagation ORF with V5 tag on 20D3Q mutant 2N4R tau

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   TagRFP.T.2A.V5

   Expression

   Mammalian

   Mutation

   20D3Q, Tau2N4R

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pcDNA3.1(-).TagRFP.T-2A-V5-8A2R.Tau2N4R-WPRE

   Plasmid

   #226384

   Purpose

   Expresses tau propagation ORF with V5 tag on 8A2R mutant 2N4R tau

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   TagRFP.T.2A.V5

   Expression

   Mammalian

   Mutation

   8A2R, Tau2N4R

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pcDNA3.1(-).TagRFP.T-2A-V5-20A3R.Tau2N4R-WPRE

   Plasmid

   #226385

   Purpose

   Expresses tau propagation ORF with V5 tag on 20A3R mutant 2N4R tau

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   TagRFP.T.2A.V5

   Expression

   Mammalian

   Mutation

   20A3R, Tau2N4R

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pcDNA3.1(-).TagRFP.T-2A-V5-K281Q.Tau2N4R-WPRE

   Plasmid

   #226386

   Purpose

   Expresses tau propagation ORF with V5 tag on K281Q mutant 2N4R tau

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   TagRFP.T.2A.V5

   Expression

   Mammalian

   Mutation

   K281Q, 2N4R

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pcDNA3.1(-).TagRFP.T-2A-V5-K353Q.Tau2N4R-WPRE

    Plasmid

    #226387

    Purpose

    Expresses tau propagation ORF with V5 tag on K353Q mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    K353Q, 2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pcDNA3.1(-).TagRFP.T-2A-V5-S198D.Tau2N4R-WPRE

    Plasmid

    #226388

    Purpose

    Expresses tau propagation ORF with V5 tag on S189D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    S198D.Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pcDNA3.1(-).TagRFP.T-2A-V5-S199D.Tau2N4R-WPRE

    Plasmid

    #226389

    Purpose

    Expresses tau propagation ORF with V5 tag on S199D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T-2A-V5

    Expression

    Mammalian

    Mutation

    S199D, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pcDNA3.1(-).TagRFP.T-2A-V5-S202D.Tau2N4R-WPRE

    Plasmid

    #226390

    Purpose

    Expresses tau propagation ORF with V5 tag on S202D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    S202D, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pcDNA3.1(-).TagRFP.T-2A-V5-S404D.Tau2N4R-WPRE

    Plasmid

    #226391

    Purpose

    Expresses tau propagation ORF with V5 tag on S404D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    S404D, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pcDNA3.1(-).TagRFP.T-2A-V5-T217D.Tau2N4R-WPRE

    Plasmid

    #226392

    Purpose

    Expresses tau propagation ORF with V5 tag on T217D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    T217D, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pcDNA3.1(-).TagRFP.T-2A-V5-T403D.Tau2N4R-WPRE

    Plasmid

    #226393

    Purpose

    Expresses tau propagation ORF with V5 tag on T403D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    T403D, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pcDNA3.1(-).TagRFP.T-2A-V5-T181D.Tau2N4R-WPRE

    Plasmid

    #226394

    Purpose

    Expresses tau propagation ORF with V5 tag on T181D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    T181D, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pcDNA3.1(-).TagRFP.T-2A-V5-T231D.Tau2N4R-WPRE

    Plasmid

    #226395

    Purpose

    Expresses tau propagation ORF with V5 tag on T231D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    T231D, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pET28.His.3C.20D3Q.Tau2N4R

    Plasmid

    #226397

    Purpose

    Expresses his-tagged, 3C-cleavable 20D3Q mutant 2N4R tau for recombinant protein production in bacteria

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    His.3C

    Expression

    Bacterial

    Mutation

    20D3Q, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pET28.His.3C.8D2Q.Tau2N4R

    Plasmid

    #226398

    Purpose

    Expresses his-tagged, 3C-cleavable 8D2Q mutant 2N4R tau for recombinant protein production in bacteria

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    His.3C

    Expression

    Bacterial

    Mutation

    8D2Q.Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge