We narrowed to 14,352 results for: Cas9

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psgRNA_EcoWG1

Pooled library

#131625

Purpose

Bacterial inhibition library targeting every small RNA and ORF of the E. coli MG1655 genome. This library has higher inhibition efficiency than the psgRNA library.

Depositor

David Bikard

Publication

Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

Expression

Bacterial

Species

Escherichia coli

Use

CRISPR

Available since

May 12, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
pCAG-eSpCas9-2A-GFP-sgRNA-PAXX

Plasmid

#257236

Purpose

To generate PAXX KO in human cells. Co-expresses eSpCas9(1.1), GFP and a guide RNA against PAXX exon 2.

Depositor

Sébastien Britton

Publication

Seif-El-Dahan et al Sci Adv. 2023 Jun 2;9(22):eadg2834. doi:

Insert

sgRNA targeting PAXX exon 2 (PAXX Human)

Expression

Mammalian

Promoter

U6

Available since

Sept. 22, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG-eSpCas9-2A-GFP-sgRNA-XLF

Plasmid

#257237

Purpose

To generate XLF KO in human cells. Co-expresses eSpCas9(1.1), GFP and a guide RNA against XLF exon 3.

Depositor

Sébastien Britton

Publication

Seif-El-Dahan et al Sci Adv. 2023 Jun 2;9(22):eadg2834. doi:

Insert

sgRNA targeting XLF exon 3 (NHEJ1 Human)

Expression

Mammalian

Promoter

U6

Available since

Sept. 22, 2026

Availability

Academic Institutions and Nonprofits only

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CAG Promoter-Driven ABE8e-dCas9-NG

Plasmid

#259160

Purpose

Mammalian base editor plasmid with CAG-driven SV40NLS-ABE8e-dCas9-NG-2A-Puro; U6 sgRNA cassette; BbsI cloning; targets NG PAM sites for A→G editing.

Depositor

Kathy Niakan

Publication

Bower et al Nature. 2026 Jun 25. doi: 10.1038/s41586

Insert

ABE8e fused to dCas9 plus a 2A-linked puromycin resistance gene

Use

CRISPR

Expression

Mammalian

Available since

Sept. 8, 2026

Availability

Academic Institutions and Nonprofits only

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Redi.3.SaCas9-V16A-I934K-L1035V

Plasmid

#235232

Purpose

Expresses reduced immunogenicity variant of SaCas9 (Redi.3.SaCas9) with mutations V16A, I934TK L1035V. Has AAV ITRs

Depositor

Feng Zhang

Publication

Raghavan et al Nat Commun. 2025 Jan 2;16(1):105. doi: 1

Insert

hSaCas9

Use

AAV and CRISPR

Expression

Mammalian

Mutation

V16A, I934K, L1035V

Available since

July 20, 2026

Availability

Academic Institutions and Nonprofits only

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MTS-ABEmax-nCas9-V5-P2A-EGFP

Plasmid

#251965

Purpose

Expression of ABEmax (with spCas9 D10A) in mitochondria for yeast mtDNA editing

Depositor

Alice Ting

Publication

Yin et al Proc Natl Acad Sci U S A. 2026 Jan 20;12

Insert

ABEmax

Use

CRISPR

Tags

MTS and V5-P2A-EGFP

Expression

Yeast

Promoter

GPD

Available since

July 1, 2026

Availability

Academic Institutions and Nonprofits only

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Redi.1.SaCas9-L9A-I934T-L1035A

Plasmid

#235230

Purpose

Expresses reduced immunogenicity variant of SaCas9 (Redi.1.SaCas9) with mutations L9A, I934T, L1035A. Has AAV ITRs

Depositor

Feng Zhang

Publication

Raghavan et al Nat Commun. 2025 Jan 2;16(1):105. doi: 1

Insert

hSaCas9

Use

AAV and CRISPR

Expression

Mammalian

Available since

June 29, 2026

Availability

Academic Institutions and Nonprofits only

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Redi.2.SaCas9-L9S-I934K-L1035V

Plasmid

#235231

Purpose

Expresses reduced immunogenicity variant of SaCas9 (Redi.2.SaCas9) with mutations L9S, I934K, L1035V. Has AAV ITRs

Depositor

Feng Zhang

Publication

Raghavan et al Nat Commun. 2025 Jan 2;16(1):105. doi: 1

Insert

hSaCas9

Use

AAV and CRISPR

Expression

Mammalian

Mutation

changed L9S, I934K, L1035V

Available since

June 23, 2026

Availability

Academic Institutions and Nonprofits only

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pFB-hSyn-SaCas9-mWPRE-hGHpA

Plasmid

#245385

Purpose

CRISPR-SaCas9 is used for in vivo genome-editing tool. Used to locate and cleave specific double-stranded DNA sequences.

Depositor

D. James Surmeier

Publication

Zhai et al Sci Adv. 2025 Dec 5;11(49):eadv8224. doi

Insert

saCas9

Use

AAV and CRISPR

Tags

SV40 NLS and nucleoplasmin NLS, 3xHA

Expression

Mammalian

Promoter

Synapsin

Available since

June 18, 2026

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pLV EF1a dCas9VP64 2A EGFP 2A BSD

Plasmid

#255458

Purpose

Expresses dCas9VP64, eGFP, and blasticidin

Depositor

Le Cong

Insert

dcas9-vp64

Expression

Mammalian

Available since

May 19, 2026

Availability

Academic Institutions and Nonprofits only

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pLV_RHOT1 sgRNA_dCas9-KRAB-T2A-EGFP

Plasmid

#253810

Purpose

Express RHOT1 sgRNA under U6 promoter and dCas9-KRAB-T2A-EGFP under hUbC promoter

Depositor

Xinnan Wang

Publication

Kwak et al bioRxiv [Preprint]. 2025 Dec 23:2025.12.

Insert

sgRNA RHOT1 (RHOT1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

sgRNA for U6p and dCas9-KRAB-T2A-GFP for hUbCp

Available since

May 13, 2026

Availability

Academic Institutions and Nonprofits only

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MTS-ABE8e-nCas9-V5-P2A-EGFP

Plasmid

#251964

Purpose

Expression of ABE8e (V106W with spCas9 D10A) in mitochondria for yeast mtDNA editing

Depositor

Alice Ting

Publication

Yin et al Proc Natl Acad Sci U S A. 2026 Jan 20;12

Insert

ABE8e

Use

CRISPR

Tags

MTS and V5-P2A-EGFP

Expression

Yeast

Promoter

GPD

Available since

March 18, 2026

Availability

Academic Institutions and Nonprofits only

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pX461-ABE8e-nSpCas9-Intergenic sgRNA

Plasmid

#237463

Purpose

All-in-one base editor expressing adenine base editor (ABE8e-nSpCas9) and gRNA control targeting Intergenic site

Depositor

Thomas Gonatopoulos-Pournatzis

Publication

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Insert

Intergenic sgRNA

Use

CRISPR

Expression

Mammalian

Promoter

chicken beta-actin promoter & U6

Available since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pX461-evoCDA1-nSpCas9-Intergenic sgRNA

Plasmid

#237464

Purpose

All-in-one base editor expressing cytosine base editor (evoCDA1-nSpCas9) and sgRNA control targeting Intergenic site

Depositor

Thomas Gonatopoulos-Pournatzis

Publication

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Insert

Intergenic sgRNA

Use

CRISPR

Expression

Mammalian

Promoter

chicken beta-actin promoter & U6

Available since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pX462-ABE8e-nSaCas9-Intergenic sgRNA

Plasmid

#237465

Purpose

All-in-one base editor expressing adenine base editor (ABE8e-nSaCas9) and sgRNA control targeting Intergenic site

Depositor

Thomas Gonatopoulos-Pournatzis

Publication

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Insert

Intergenic sgRNA

Use

CRISPR

Expression

Mammalian

Promoter

chicken beta-actin promoter & U6

Available since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pX461-ABE8e-nSpCas9-NRF1-ss-sgRNA

Plasmid

#237466

Purpose

All-in-one adenine base editor (ABE8e-nSpCas9) with gRNA targeting NRF1-Ex7 splice site

Depositor

Thomas Gonatopoulos-Pournatzis

Publication

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Insert

gRNA targeting NRF1-Ex7 splice site

Use

CRISPR

Expression

Mammalian

Promoter

chicken beta-actin promoter & U6

Available since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pX461-evoCDA1-nSpCas9-NRF1-ss-sgRNA

Plasmid

#237467

Purpose

All-in-one cytosine base editor (evoCDA1-nSpCas9) with sgRNA targeting NRF1-Ex7 splice site

Depositor

Thomas Gonatopoulos-Pournatzis

Publication

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Insert

sgRNA targeting NRF1-Ex7 splice site

Use

CRISPR

Expression

Mammalian

Promoter

chicken beta-actin promoter & U6

Available since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pX462-ABE8e-nSaCas9-NRF1-ss-sgRNA

Plasmid

#237468

Purpose

All-in-one adenine base editor (ABE8e-nSaCas9) with gRNA targeting NRF1-Ex7 splice site

Depositor

Thomas Gonatopoulos-Pournatzis

Publication

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Insert

gRNA targeting NRF1-Ex7 splice site

Use

CRISPR

Expression

Mammalian

Promoter

chicken beta-actin promoter & U6

Available since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pEvolvR-mCherry-enCas9(D10A)-PolI5MΔ

Plasmid

#249068

Purpose

Expresses nucleus-localized enCas9 (D10A) fused to PolI5MΔ and mCherry using a CMV promoter. Includes a GFP cassette flanked by BsmbI cut sites to knock in and coexpress user-defined gRNAs.

Depositor

John Dueber, David Schaffer

Publication

Hurtado et al Nat Commun. 2025 Apr 19;16(1):3723. doi:

Insert

enCas9-PolI5MΔ

Use

CRISPR

Tags

mCherry

Expression

Mammalian

Mutation

deletion of PolI5M N-terminal flap endonuclease d…

Promoter

CMV

Available since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-CMV-DIO-SaCas9-U6-sgDaglb

Plasmid

#240023

Purpose

Knockdown expression of Daglb

Depositor

Huaibin Cai

Publication

Liu et al Nat Commun. 2022 Jun 17;13(1):3490. doi:

Insert

diacylglycerol lipase, beta (Daglb Mouse)

Use

AAV, CRISPR, and Mouse Targeting

Promoter

CMV

Available since

Jan. 6, 2026

Availability

Academic Institutions and Nonprofits only

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