We narrowed to 119 results for: mutant p53

1. pRetroX-TRE3G-IRSp53 P278D P281D

   Plasmid

   #221320

   Purpose

   Dox-inducible expression of IRSp53 mutant in mammalian cells by retroviral transduction

   Depositor

   Jonathan Kagan

   Article

   Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

   Insert

   IRSp53 (Baiap2 Mouse)
   

   Use

   Retroviral

   Tags

   3xFLAG

   Expression

   Mutation

   P278D P281D

   Promoter

   TRE3G

   Available since

   July 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pMSCV-FKBP-IRSp53(pLxIS) S269A

   Plasmid

   #221269

   Purpose

   Expression of IRSp53 pLxIS mutant in mammalian cells by retroviral transduction

   Depositor

   Jonathan Kagan

   Article

   Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

   Insert

   IRSp53 pLxIS (Baiap2 Mouse)
   

   Use

   Retroviral

   Tags

   3xFLAG-4xFKBP

   Expression

   Mutation

   S269A

   Promoter

   Available since

   July 10, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. MG15-luc (mut p53 binding sites)

   Plasmid

   #16443

   Depositor

   Bert Vogelstein

   Article

   el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25.

   Insert

   p53-binding site (mutant) (TP53 )
   

   Use

   Luciferase

   Tags

   luciferase

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 12, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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4. MG15-gal (mut p53 binding sites)

   Plasmid

   #16447

   Depositor

   Bert Vogelstein

   Article

   el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25.

   Insert

   p53-binding site (mutant) (TP53 )
   

   Use

   Beta-gal reporter

   Tags

   beta-gal

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 12, 2008

   Availability

   Academic Institutions and Nonprofits only

5. pLX313-TP53-P278A

   Plasmid

   #118015

   Purpose

   Constitutive expression of mutant human Tumor Protein p53 (TP53)

   Depositor

   David Root, William Hahn

   Article

   Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

   Insert

   TP53 (TP53 Human)
   

   Use

   Lentiviral

   Tags

   V5

   Expression

   Mammalian

   Mutation

   p.Pro278Ala

   Promoter

   EF1alpha

   Available since

   Oct. 29, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pGLS3-5xHRE-p53(K120R/K164R)

   Plasmid

   #72556

   Purpose

   Hypoxia induced mutant p53. Contains the HRE from VEGF sequence (5 repeats) upstream of p53 K120R/K164R.

   Depositor

   Ester Hammond

   Article

   Leszczynska et al J Clin Invest. 2015 Jun;125(6):2385-98.

   Insert

   p53 (TP53 Human)
   

   Use

   Tags

   5XHRE

   Expression

   Mammalian

   Mutation

   K120R/K164R

   Promoter

   E1B minimal promoter

   Available since

   March 15, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. HA-HIF2α P405A/P531A/N847A-pBabe-Puro

   Plasmid

   #25956

   Depositor

   William Kaelin

   Article

   Yan et al Mol Cell Biol. 2007 Mar . 27(6):2092-102

   Insert

   Hypoxia inducible factor 2 alpha (EPAS1 Human)
   

   Use

   Retroviral

   Tags

   HA-tag

   Expression

   Mammalian

   Mutation

   cDNA changed amino acids: Proline 405 to Alanin…

   Promoter

   Available since

   Oct. 19, 2010

   Availability

   Academic Institutions and Nonprofits only

   

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8. HA-HIF2α P405A/P531A/N847Q-pBabe-Puro

   Plasmid

   #25948

   Depositor

   William Kaelin

   Article

   Yan et al Mol Cell Biol. 2007 Mar . 27(6):2092-102

   Insert

   Hypoxia inducible factor 2 alpha (EPAS1 Human)
   

   Use

   Retroviral

   Tags

   HA-tag

   Expression

   Mammalian

   Mutation

   cDNA changed amino acids: Proline 405 to Alanin…

   Promoter

   Available since

   Sept. 20, 2010

   Availability

   Academic Institutions and Nonprofits only

   

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9. HA-HIF2α P405A/P531A Δ820-870-pBabe-Puro

   Plasmid

   #25949

   Depositor

   William Kaelin

   Article

   Yan et al Mol Cell Biol. 2007 Mar . 27(6):2092-102

   Insert

   Hypoxia inducible factor 2 alpha (EPAS1 Human)
   

   Use

   Retroviral

   Tags

   HA-tag

   Expression

   Mammalian

   Mutation

   cDNA changed amino acids: Proline 405 to Alanin…

   Promoter

   Available since

   Oct. 4, 2010

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. HA-HIF2α bHLH* P405A/P531A Δ820-870-pBabe-Puro

    Plasmid

    #25957

    Depositor

    William Kaelin

    Article

    Yan et al Mol Cell Biol. 2007 Mar . 27(6):2092-102

    Insert

    Hypoxia inducible factor 2 alpha (EPAS1 Human)
    

    Use

    Retroviral

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    cDNA changed amino acids: Proline 405 to Alanin…

    Promoter

    Available since

    Sept. 22, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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11. sox10:PDGFRA mutant

    Plasmid

    #98697

    Purpose

    I-SceI meganuclease-mediated human PDGFRA mutant transgenesis in zebrafish

    Depositor

    Thomas Look

    Article

    Ki et al Oncogene. 2017 Feb 23;36(8):1058-1068. d

    Insert

    PDGFRA (PDGFRA Human)
    

    Use

    Zebrafish expression

    Tags

    Expression

    Mutation

    exon 8 and 9 deletion

    Promoter

    Available since

    July 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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12. pGL3-CMV-p85a 3'UTR mutant

    Plasmid

    #51393

    Depositor

    Narry Kim

    Article

    Park et al Nat Struct Mol Biol. 2009 Jan;16(1):23-9

    Insert

    p85alpha 3'UTR (PIK3R1 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mutation

    miR-29 binding site mutant

    Promoter

    CMV

    Available since

    March 31, 2014

    Availability

    Academic Institutions and Nonprofits only

13. TP53 MITE Library

    Pooled Library

    #113569

    Purpose

    Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

    Depositor

    David Root, William Hahn

    Article

    Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

14. pGL3-CMV-Cdc42 3'UTR mutant (position 577-599)

    Plasmid

    #51391

    Depositor

    Narry Kim

    Article

    Park et al Nat Struct Mol Biol. 2009 Jan;16(1):23-9

    Insert

    NM_001039802.1 (CDC42 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mutation

    miR-29 binding site mutant (position 577-599)

    Promoter

    CMV

    Available since

    March 31, 2014

    Availability

    Academic Institutions and Nonprofits only

15. pGL3-CMV-Cdc42 3'UTR mutant (position 577-599 and 997-1019)

    Plasmid

    #51390

    Depositor

    Narry Kim

    Article

    Park et al Nat Struct Mol Biol. 2009 Jan;16(1):23-9

    Insert

    NM_001039802.1 (CDC42 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mutation

    miR-29 binding site mutant (position 577-599, 997…

    Promoter

    CMV

    Available since

    March 31, 2014

    Availability

    Academic Institutions and Nonprofits only

16. Target Accelerator Pan-Cancer Mutant Collection

    Plasmid Kit

    #1000000103

    Purpose

    Panel of cancer alleles that have undergone basic, functional screening; full-length, human clones (454 mutant and 177 corresponding wild-type) in the Gateway cloning system

    Depositor

    Jesse Boehm

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

17. Target Accelerator Lung Cancer Mutant Collection

    Plasmid Kit

    #1000000104

    Purpose

    Panel of lung adenocarcinoma alleles that have undergone basic, functional screening; full-length human clones (180 mutant and 45 corresponding wild-type) and 82 wild-type experssion controls

    Depositor

    Jesse Boehm

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

18. pX68

    Plasmid

    #46857

    Purpose

    OP Hupki-puro2A-A138V plasmid to indroduce mutant p53 to PLF ESC or MEFs by IMCE

    Depositor

    Monica Hollstein

    Article

    Wei et al Cell Cycle. 2011 Apr 15;10(8):1261-70. E

    Insert

    attB-Puro-2A and Hupki p53 A138V (TP53 Human, Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    p53 A138V

    Promoter

    Available since

    Aug. 22, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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19. pX62

    Plasmid

    #46854

    Purpose

    TOP Hupki-puro2A-G245S plasmid to introduce mutant p53 to PLF ESC or MEFs by IMCE

    Depositor

    Monica Hollstein

    Article

    Wei et al Cell Cycle. 2011 Apr 15;10(8):1261-70. E

    Insert

    attB-Puro-2A and Hupki p53 G245S (TP53 Human, Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    G245S

    Promoter

    Available since

    Aug. 22, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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20. pBabe 12S E1A

    Plasmid

    #18742

    Depositor

    Scott Lowe

    Article

    Samuelson et al Proc Natl Acad Sci U S A. 1997 Oct 28. 9

    Insert

    12S E1A
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 3, 2008

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge