We narrowed to 15,981 results for: LEA

1. alpha Synuclein-VC

   Plasmid

   #89471

   Purpose

   expresses human alpha Synuclein fused to the C-terminal part of Venus

   Depositor

   Tiago Outeiro, Bradley Hyman

   Article

   Outeiro et al PLoS One. 2008 Apr 2;3(4):e1867. doi: 10

   Insert

   SNCA (SNCA Human)
   

   Tags

   C-terminal part of Venus

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Dec. 11, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLKO.1 puro_shDDX58_230212

   Plasmid

   #167293

   Purpose

   Lentiviral plKO.1 construct coding for a short-hairpin RNA targeting the human gene DDX58 (coding for RLR sensor RIG-I). Contains a puro resistance cassette.

   Depositor

   Agnel Sfeir

   Article

   Tigano et al Nature. 2021 Mar;591(7850):477-481. doi:

   Insert

   shRNA hsDDX58 (RIGI Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Available Since

   April 21, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. pColdI-GST-mGTSF1

   Plasmid

   #214671

   Purpose

   Bacterial expression of GST-tagged mouse GTSF1

   Depositor

   Phillip Zamore

   Article

   Arif et al Nature. 2022 Aug;608(7923):618-625. doi:

   Insert

   GTSF1 (Gtsf1 Mouse)
   

   Tags

   6x His and GST

   Expression

   Bacterial

   Promoter

   CspA

   Available Since

   March 20, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pTRIP-SFFV-tagBFP-2A-ICP0-FxE

   Plasmid

   #235539

   Purpose

   To express tagBFP-2A-ICP0-FXE (ICP0 ∆106-149)

   Depositor

   Nicolas Manel

   Article

   Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

   Insert

   ICP0-FxE
   

   Use

   Lentiviral

   Mutation

   Deletion of the RING domain, ∆106-149.

   Available Since

   July 17, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. AAVi U6_gRNA CMV_SadCas9-KRAB

   Plasmid

   #214609

   Purpose

   All-in-one AAVi plasmid expressing S. aureus dCas9-KRAB with sgRNA cassette

   Depositor

   Ralf Gilsbach

   Article

   Laurette et al Circ Res. 2023 Dec 22. doi: 10.1161/CIRC

   Inserts

   gRNA
   SadCas9
   

   Use

   AAV

   Tags

   NP NLS and SV40 NLS

   Expression

   Mammalian

   Mutation

   D10A, N580A

   Promoter

   CMV and U6

   Available Since

   March 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pcDNA3-Delta(Pro-MP)ADAM10-HA

   Plasmid

   #65107

   Purpose

   Expression of HA tagged ADAM10 lacking prodomain and metalloprotease domain in mammalian cells

   Depositor

   Axel Ullrich

   Article

   Gschwind et al EMBO J. 2003 May 15;22(10):2411-21.

   Insert

   Delta(Pro-MP)ADAM10 (ADAM10 Human)
   

   Tags

   HA

   Expression

   Mammalian

   Mutation

   deleted AA 19-455

   Promoter

   CMV

   Available Since

   Nov. 7, 2016

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-Ef1a-dDIO hChR2(H134R)-EYFP

   Plasmid

   #55640

   Purpose

   Dre-Dependent ChR2-EYFP

   Depositor

   Karl Deisseroth

   Article

   Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

   Insert

   hChR2(H134R)-EYFP
   

   Use

   AAV

   Tags

   EYFP

   Expression

   Mammalian

   Promoter

   Ef1a

   Available Since

   Aug. 8, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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8. SpCas9-ABE8e(V106W)

   Plasmid

   #198547

   Purpose

   Expresses human codon-optimized SpCas9-ABE8e(V106W) and blasticidin resistance: EFS promoter-SpCas9-ABE8e(V106W)-NLS-FLAG-P2A-BSD

   Depositor

   Hyongbum Kim

   Article

   Kim et al Nat Biotechnol. 2024 Mar;42(3):484-497.

   Insert

   SpCas9-ABE8e(V106W)
   

   Use

   CRISPR and Lentiviral

   Tags

   BSD, FLAG, and NLS

   Expression

   Mammalian

   Promoter

   EFS

   Available Since

   Nov. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pSynapsin_NLS_GFP_P2A_His6_NR1.

   Plasmid

   #170457

   Purpose

   Expresses histidine tagged NR1 in neuronal cells

   Depositor

   Shigeki Watanabe

   Article

   Li et al Nat Commun. 2021 Jan 29;12(1):677. doi:

   Insert

   NR1 (Grin1 Rat)
   

   Use

   Lentiviral

   Tags

   Hexa-histidin

   Expression

   Mammalian

   Promoter

   Synapsin

   Available Since

   July 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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10. pBactin-mNeonGreen-CI

    Plasmid

    #196850

    Purpose

    Expression of green fluorescent reporter mNeonGreen driven by the strong Beta-actin promoter

    Depositor

    Frank Bradke

    Article

    Vinopal et al Neuron. 2023 Apr 19;111(8):1241-1263.e16

    Insert

    mNeonGreen
    

    Expression

    Mammalian

    Mutation

    None (wt)

    Promoter

    Chicken bactin (plus Chicken bactin intron)

    Available Since

    May 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. VN-alpha Synuclein

    Plasmid

    #89470

    Purpose

    expresses human alpha Synuclein fused to the N-terminal part of Venus

    Depositor

    Tiago Outeiro, Bradley Hyman

    Article

    Outeiro et al PLoS One. 2008 Apr 2;3(4):e1867. doi: 10

    Insert

    SNCA (SNCA Human)
    

    Tags

    N-terminal part of Venus

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Nov. 21, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. pGL3-NBRE3

    Plasmid

    #208254

    Purpose

    pGL3 promoter luciferase reporter vector containing 3 copies of the NBRE DNA response element (5′-GAGTTTTAAAAGGTCATGCTCAATT TGTC-3′) used for luciferase reporter assays in mammalian cells

    Depositor

    Douglas Kojetin

    Article

    Munoz-Tello et al J Med Chem. 2020 Dec 24;63(24):15639-156

    Insert

    3X NBRE-LUC
    

    Expression

    Mammalian

    Promoter

    SV40 early promoter

    Available Since

    Feb. 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. p3E_BAG3wt-eGFP

    Plasmid

    #98180

    Purpose

    Codes for full length, GFP tagged, human wildtype Bag3

    Depositor

    Robert Bryson-Richardson

    Article

    Ruparelia et al Acta Neuropathol. 2014 Dec;128(6):821-33

    Insert

    BAG3wt-eGFP (BAG3 Human)
    

    Use

    Gateway vector

    Tags

    GFP

    Available Since

    June 30, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-syn-FLEX-splitTVA-EGFP-tTA

    Plasmid

    #100798

    Purpose

    helper virus for monosynaptic tracing; to be coinjected with pAAV-TREtight-mTagBFP2-B19G

    Depositor

    Ian Wickersham

    Article

    Liu et al Nature. 2017 Aug 31;548(7669):582-587. d

    Has Service

    AAV1

    Insert

    TVA, EGFP, tet transactivator
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    synapsin

    Available Since

    Oct. 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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15. PET-B-Sniper SpCas9-NLS-6xHis

    Plasmid

    #207377

    Purpose

    Expression of increased-fidelity (i.e. high-fidelity) SpCas9 variant in bacterial cells

    Depositor

    Ervin Welker

    Article

    Kulcsar et al Nat Commun. 2023 Sep 16;14(1):5746. doi:

    Insert

    B-Sniper SpCas9
    

    Use

    CRISPR

    Tags

    6xHis

    Expression

    Bacterial

    Mutation

    F539S, M763I, K890N, amino acids 1005-1013 replac…

    Promoter

    T7

    Available Since

    Sept. 25, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. GFP-Drosha

    Plasmid

    #62520

    Purpose

    wild-type human Drosha cDNA is subcloned into pEGFP-C1 vector between HindIII and KpnI sites

    Depositor

    Bharat Ramratnam

    Article

    Tang et al Nucleic Acids Res. 2010 Oct;38(19):6610-

    Insert

    human Drosha full length (DROSHA Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Available Since

    March 20, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-EF1a-ArgiNLS-mGreenLantern

    Plasmid

    #220596

    Purpose

    Constitutive expression of a single-cell discriminating version of mGreenLantern fluorescent protein.

    Depositor

    Sam Golden

    Article

    Szelenyi et al Proc Natl Acad Sci U S A. 2024 Aug 6;121

    Insert

    mGreenLantern
    

    Use

    AAV

    Tags

    ArgiNLS

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    July 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pcDNA3 P-cad

    Plasmid

    #47502

    Purpose

    Expresses P-cadherin in mammalian cells

    Depositor

    Alice Wong

    Article

    Cheung et al Oncogene. 2010 Apr 22;29(16):2427-40. do

    Insert

    cadherin 3, type 1, P-cadherin (placental) (CDH3 Human)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Sept. 26, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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19. PUC57_BAG3wt-eGFP

    Plasmid

    #98182

    Purpose

    Codes for full length, GFP tagged, human wildtype Bag3

    Depositor

    Robert Bryson-Richardson

    Article

    Ruparelia et al Acta Neuropathol. 2014 Dec;128(6):821-33

    Insert

    BAG3wt-eGFP (BAG3 Human)
    

    Tags

    GFP

    Expression

    Bacterial

    Available Since

    June 30, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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20. pSynapsin_NLS_GFP_P2A_Halo_GluA2

    Plasmid

    #170454

    Purpose

    Expresses halo tagged GluA2 in neuronal cells

    Depositor

    Shigeki Watanabe

    Article

    Li et al Nat Commun. 2021 Jan 29;12(1):677. doi:

    Insert

    GluA2 (Gria2 Mouse)
    

    Use

    Lentiviral

    Tags

    Halo

    Expression

    Mammalian

    Promoter

    Synapsin

    Available Since

    July 14, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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