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We narrowed to 9,163 results for: Ott;

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Showing: 6621 - 6640 of 9163 results

  3. pLV[Exp]-Bsd-CMV>hCDK11B D562A, G579S

    Plasmid
    #239218
    Purpose
    Expresses CDK11B with D562A kinase inactivating mutation and G579S resistance mutation in mammalian cell lines
    Depositor
    Jason Sheltzer
    Article
    Julian et al bioRxiv 2025.08.03.668359; doi: https://
    Insert
    cyclin dependent kinase 11B with D562A kinase inactivating mutation and G579S resistance mutation (CDK11B Human)
    Use
    Lentiviral
    Expression
    Mammalian
    Mutation
    changed Aspartic acid 562 to Alanine and changed …
    Available Since
    Aug. 5, 2025
    Availability
    Academic Institutions and Nonprofits only
    239218-plasmid-map-sequence-id-476822

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  4. pMJ1.19 (AAVS1 RNA donor in pCDNA3.1)

    Plasmid
    #238007
    Purpose
    300bp donor RNA complementary to Cas9 cut site at AAVS1 (Addgene plasmid #72833) with intronic sequence intervening the 3bp insertion signature (ATC). Can be used to measure RT-DSBR in human cells.
    Depositor
    Simon Powell, Agnel Sfeir
    Article
    Jalan et al Nat Commun. 2025 May 10;16(1):4349. doi:
    Insert
    AAVS1 (AAVS1, PPP1R12C Human)
    Use
    Rna donor to study rt-dsbr
    Expression
    Mammalian
    Mutation
    3bp insertion signature (ATC) at Cas9 cut site in…
    Promoter
    CMV
    Available Since
    May 14, 2025
    Availability
    Academic Institutions and Nonprofits only
    238007-plasmid-map-sequence-id-472649

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  6. pMT870 human L1 RT- (ORF2p D702Y) ORF2p-3xFlag (ORFeus-Hs, CMV promoter) in pCEP4 Puro (derivative of pMT646)

    Plasmid
    #213027
    Purpose
    Expresses reverse transcriptase dead (RT- ORF2p D702Y) full length human LINE-1 in human cells (codon optimized ORFeus-Hs), with a C-terminal 3xFlag tag on ORF2
    Depositor
    Martin S. Taylor
    Article
    Baldwin et al Nature. 2024 Feb;626(7997):194-206. doi:
    Insert
    Human LINE-1 (ORFeus-Hs codon optimized sequence, RT- D702Y) with ORF2-3xFlag
    Tags
    3xFlag (ORF2p)
    Expression
    Mammalian
    Mutation
    D702Y (RT- reverse transcriptase catalytic dead)
    Promoter
    CMV
    Available Since
    Nov. 14, 2024
    Availability
    Academic Institutions and Nonprofits only
    213027-plasmid-map-sequence-id-452358

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  8. pMT647 human L1 ORF2p-3xFlag only (ORFeus-Hs, CMV promoter, monocistronic construct) in pCEP4 Puro (derivative of pMT646)

    Plasmid
    #213029
    Purpose
    Expresses human LINE-1 ORF2 only in human cells (codon optimized ORFeus-Hs), with a C-terminal 3xFlag tag on ORF2
    Depositor
    Martin S. Taylor
    Article
    Baldwin et al Nature. 2024 Feb;626(7997):194-206. doi:
    Insert
    Human LINE-1 ORF2p only (monocistronic, codon optimized ORFeus-Hs sequence) with ORF2-3xFlag
    Tags
    3xFlag
    Expression
    Mammalian
    Promoter
    CMV
    Available Since
    May 6, 2024
    Availability
    Academic Institutions and Nonprofits only
    213029-plasmid-map-sequence-id-422050

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  9. pMT1093 human L1 EN- (ORF2p E43S, D145N) ORF2p-3xFlag (ORFeus-Hs, CMV promoter) in pCEP4 Puro (derivative of pMT646)

    Plasmid
    #213028
    Purpose
    Expresses endonuclease dead (EN- ORF2p E43S, D145N) full length human LINE-1 in human cells (codon optimized ORFeus-Hs), with a C-terminal 3xFlag tag on ORF2
    Depositor
    Martin S. Taylor
    Article
    Baldwin et al Nature. 2024 Feb;626(7997):194-206. doi:
    Insert
    Human LINE-1 (ORFeus-Hs codon optimized sequence, EN- E43S D145N) with ORF2-3xFlag
    Tags
    3xFlag (ORF2p)
    Expression
    Mammalian
    Mutation
    E43S D145N double mutant EN- endonuclease catalyt…
    Promoter
    CMV
    Available Since
    May 6, 2024
    Availability
    Academic Institutions and Nonprofits only
    213028-plasmid-map-sequence-id-422046

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  11. pLenti-EML4-ALK variant 3a I1171N/D1203N

    Plasmid
    #183833
    Purpose
    Express EML4-ALK fusion variant 3a (E6a;A20) harboring ALK I1171N/D1203N mutation in mammalian cells
    Depositor
    Aaron Hata
    Article
    Shiba-Ishii et al Nat Cancer. 2022 Jun 20. pii: 10.1038/s4
    Inserts
    ALK Receptor Tyrosine Kinase (ALK Human)
    EMAP Like 4 (EML4 Human)
    Use
    Lentiviral
    Tags
    The fusion protein of EML4 exon 1-6a and ALK exon…
    Expression
    Mammalian
    Mutation
    I1171N/D1203N
    Promoter
    CMV
    Available Since
    June 22, 2022
    Availability
    Academic Institutions and Nonprofits only
    183833-plasmid-map-sequence-id-360485

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  16. Lenti-CMV-mCherry-GSG-P2A-NUDT5 G150V-WPRE

    Plasmid
    #250402
    Purpose
    Lentiviral expression of human NUDT5 G150V with N-terminal mCherry seperated by a flexible GSG-linker and P2A under CMV promoter, as well as a puromycin resistance cassette under PGK promoter.
    Depositor
    Stefan Kubicek
    Article
    Nguyen et al Science. 2025 Nov 6:eadv4257. doi: 10.11
    Insert
    NUDT5 (NUDT5 Human)
    Use
    Lentiviral
    Tags
    mCherry-GSG-P2A
    Expression
    Mammalian
    Mutation
    G150V
    Promoter
    CMV
    Available Since
    Feb. 3, 2026
    Availability
    Academic Institutions and Nonprofits only
    250402-plasmid-map-sequence-id-498983

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  17. Lenti-CMV-mCherry-GSG-P2A-NUDT5 P158I-WPRE

    Plasmid
    #250403
    Purpose
    Lentiviral expression of human NUDT5 P158I with N-terminal mCherry seperated by a flexible GSG-linker and P2A under CMV promoter, as well as a puromycin resistance cassette under PGK promoter.
    Depositor
    Stefan Kubicek
    Article
    Nguyen et al Science. 2025 Nov 6:eadv4257. doi: 10.11
    Insert
    NUDT5 (NUDT5 Human)
    Use
    Lentiviral
    Tags
    mCherry-GSG-P2A
    Expression
    Mammalian
    Mutation
    P158I
    Promoter
    CMV
    Available Since
    Feb. 3, 2026
    Availability
    Academic Institutions and Nonprofits only
    250403-plasmid-map-sequence-id-498982

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  20. Lenti-CMV-mCherry-GSG-P2A-NUDT5 W28A-WPRE

    Plasmid
    #250389
    Purpose
    Lentiviral expression of human NUDT5 W28A with N-terminal mCherry seperated by a flexible GSG-linker and P2A under CMV promoter, as well as a puromycin resistance cassette under PGK promoter.
    Depositor
    Stefan Kubicek
    Article
    Nguyen et al Science. 2025 Nov 6:eadv4257. doi: 10.11
    Insert
    NUDT5 (NUDT5 Human)
    Use
    Lentiviral
    Tags
    mCherry-GSG-P2A
    Expression
    Mammalian
    Mutation
    W28A
    Promoter
    CMV
    Available Since
    Feb. 3, 2026
    Availability
    Academic Institutions and Nonprofits only
    250389-plasmid-map-sequence-id-498981

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Showing: 6621 - 6640 of 9163 results