We narrowed to 18,501 results for: MUT

1. pDONR223_MAPK7_WT

   Plasmid

   #82925

   Purpose

   Gateway Donor vector containing MAPK7, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, Matthew Meyerson, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   NM_002749.3 (MAPK7 Human)
   

   Use

   Gateway entry vector

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. pHAGE-DDR2

   Plasmid

   #116729

   Purpose

   Lentiviral expression of DDR2

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   DDR2 (DDR2 Human)
   

   Use

   Lentiviral

   Mutation

   WT

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pcDNA3.1(+)-NES-ZapCV2 (cpV143)

   Plasmid

   #112060

   Purpose

   Genetically-encoded Cyan-Yellow Zinc FRET sensor. Localizes to the cytosol. Useful for detecting free zinc ion levels in the cytosol (in vitro Kd ~2.3 nM, n = 0.53)

   Depositor

   Amy Palmer

   Article

   Fiedler et al Anal Chem. 2017 Jan 3;89(1):711-719. doi

   Insert

   NES-ZapCV2
   

   Tags

   Nuclear Export Signal (NES) derived from HIV-1

   Expression

   Mammalian

   Mutation

   ECFP gene is truncated 36 bp at 3' end. Venu…

   Promoter

   CMV

   Available Since

   July 25, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pHAGE-PTPN11

   Plasmid

   #116782

   Purpose

   Lentiviral expression of PTPN11

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   PTPN11 (PTPN11 Human)
   

   Use

   Lentiviral

   Mutation

   WT

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. pDNA2.0 6H-TEV-KRAS G13D

   Plasmid

   #111851

   Purpose

   Expresses activated human KRAS G13D (amino acids 1 - 169) in E. coli with amino terminal 6xHIS tag that can be removed with TEV protease.

   Depositor

   Kenneth Westover

   Article

   Hunter et al Mol Cancer Res. 2015 Sep;13(9):1325-35.

   Insert

   KRAS G13D (KRAS Human)
   

   Tags

   6xHis-tag and TEV protease cleavage sequence

   Expression

   Bacterial

   Mutation

   Changed Glycine 13 to Aspartic Acid

   Promoter

   T5

   Available Since

   June 20, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pHAGE-PDGFRA-V561D

   Plasmid

   #116452

   Purpose

   Lentiviral expression of PDGFRA V561D

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   PDGFRA (PDGFRA Human)
   

   Use

   Lentiviral

   Mutation

   V561D

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pHAGE-EGFR-L62R

   Plasmid

   #116265

   Purpose

   Lentiviral expression of EGFR L62R

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   EGFR (EGFR Human)
   

   Use

   Lentiviral

   Mutation

   L62R

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pInducer-myc-ERK1-R84S

   Plasmid

   #213591

   Purpose

   Doxycycline inducible expression of myc-tagged ERK1-R84S cDNA in mammilian cells

   Depositor

   Channing Der

   Article

   Klomp et al Science. 2024 Jun 7;384(6700):eadk0850.

   Insert

   MAPK3 (MAPK3 Human)
   

   Use

   Lentiviral

   Tags

   MYC

   Expression

   Mammalian

   Mutation

   R84S

   Available Since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pHAGE-BRAF-V600K

   Plasmid

   #116206

   Purpose

   Lentiviral expression of BRAF V600K

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   BRAF (BRAF Human)
   

   Use

   Lentiviral

   Mutation

   V600K

   Available Since

   Jan. 11, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. pBacMam2-DiEx-LIC-C-flag_huntingtin_full-length_Q48

    Plasmid

    #111747

    Purpose

    Baculovirus transfer vector for expression of huntingtin protein in insect and mammalian cellscells as well as in mammalian cells

    Depositor

    Cheryl Arrowsmith

    Article

    Harding et al J Biol Chem. 2019 Apr 26;294(17):6986-70

    Insert

    HTT (HTT Human)
    

    Use

    Baculovirus expression

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Q48 (polyQ repeat)

    Promoter

    CMV and P10

    Available Since

    Aug. 29, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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11. pHAGE-EGFR-R108K

    Plasmid

    #116292

    Purpose

    Lentiviral expression of EGFR R108K

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    EGFR (EGFR Human)
    

    Use

    Lentiviral

    Mutation

    R108K

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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12. pHAGE-ALK-R1275Q

    Plasmid

    #116111

    Purpose

    Lentiviral expression of ALK R1275Q

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    ALK (ALK Human)
    

    Use

    Lentiviral

    Mutation

    R1275Q

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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13. pBacMam2-DiEx-LIC-N-flag_huntingtin_full-length_Q51

    Plasmid

    #111734

    Purpose

    Baculovirus transfer vector for expression of huntingtin protein in insect and mammalian cellscells as well as in mammalian cells

    Depositor

    Cheryl Arrowsmith

    Article

    Harding et al J Biol Chem. 2019 Apr 26;294(17):6986-70

    Insert

    HTT (HTT Human)
    

    Use

    Baculovirus expression

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Q51 (polyQ repeat)

    Promoter

    CMV and P10

    Available Since

    Aug. 29, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcDNA5 FRT/TO SF-HERC2 C4762S (ShB-R)

    Plasmid

    #55614

    Purpose

    Dox-inducible expression of full length, ShB-resistant, 3xFLAG/STREP tagged C4762S (catalytically inactive) HERC2 in Flp-In T-Rex cells

    Depositor

    David Chan

    Article

    Chan et al J Biol Chem. 2014 May 22. pii: jbc.M114.

    Insert

    3xFLAG tagged HERC2 (C4762S) (HERC2 Human)
    

    Tags

    3xFLAG and STREP

    Expression

    Mammalian

    Mutation

    C4762 mutated to serine to render HERC2 catalytic…

    Available Since

    Sept. 25, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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15. Zebrafish ArcLight Q175

    Plasmid

    #53616

    Purpose

    Genetically encoded voltage sensor ArcLight with improved kinetics

    Depositor

    Vincent Pieribone

    Article

    Han et al PLoS One. 2013 Nov 27;8(11):e81295. doi:

    Insert

    Zebrafish ArcLight-Q175 (tpte Zebrafish, Synthetic, Aequorea victoria)
    

    Expression

    Mammalian

    Mutation

    Dr-VSD contains R153Q mutation and an amino acid …

    Promoter

    CMV

    Available Since

    Aug. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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16. Lenti-RNF2-tevopreQ1-epegRNA+5G>T_EF1a-puroR

    Plasmid

    #207355

    Purpose

    Lentiviral transfer plasmid encoding hU6-driven expression of a RNF2 engineered prime editing guide (epegRNA) and EF1a-driven puromycin resistance gene.

    Depositor

    Marianne Carlon

    Article

    Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

    Insert

    RNF2 + 5G>T tevopreq1-prime editing guide RNA (epegRNA)
    

    Use

    Lentiviral

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pHAGE-PIK3CA-Q546K

    Plasmid

    #116527

    Purpose

    Lentiviral expression of PIK3CA Q546K

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3CA (PIK3CA Human)
    

    Use

    Lentiviral

    Mutation

    Q546K

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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18. pHAGE-NFE2L2

    Plasmid

    #116765

    Purpose

    Lentiviral expression of NFE2L2

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    NFE2L2 (NFE2L2 Human)
    

    Use

    Lentiviral

    Mutation

    WT

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. pdCas9-DNMT3A-PuroR_BACH2-sgRNA8 (ANV)

    Plasmid

    #71829

    Purpose

    Expression of mutant dCas9-DNMT3A fusion (inactive catalytic domain of DNMT3A) with T2A-PuroR and specific sgRNA for the human BACH2 promoter; for use as a control

    Depositor

    Vlatka Zoldos

    Article

    Vojta et al Nucleic Acids Res. 2016 Mar 11. pii: gkw

    Insert

    BACH2-sgRNA8 (BACH2 S. pyogenes, Synthetic, Human)
    

    Use

    CRISPR

    Tags

    3xFLAG, SV40 NLS, and T2A-PuroR

    Expression

    Mammalian

    Mutation

    D10A and H840A in S.pyogenes Cas9; E756A inactiva…

    Promoter

    U6

    Available Since

    March 7, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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20. pHAGE-AKT1

    Plasmid

    #116710

    Purpose

    Lentiviral expression of AKT1

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    AKT1 (AKT1 Human)
    

    Use

    Lentiviral

    Mutation

    WT

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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