We narrowed to 1,090 results for: FIB

1. pcDNA3.1-IDO2-p2a-eGFP

   Plasmid

   #187027

   Purpose

   Expresses IDO2 and GFP (seperately) in mammalian cells

   Depositor

   Geert van den Bogaart

   Article

   Maassen et al Free Radic Biol Med. 2022 Aug 1;188:287-

   Insert

   Indoleamine 2,3-dioxygenase 2 (IDO2 Human)
   

   Tags

   P2A-GFP

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Sept. 23, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. Lenti-RNF2-tevopreQ1-epegRNA+5G>T_EF1a-puroR

   Plasmid

   #207355

   Purpose

   Lentiviral transfer plasmid encoding hU6-driven expression of a RNF2 engineered prime editing guide (epegRNA) and EF1a-driven puromycin resistance gene.

   Depositor

   Marianne Carlon

   Article

   Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

   Insert

   RNF2 + 5G>T tevopreq1-prime editing guide RNA (epegRNA)
   

   Use

   Lentiviral

   Available Since

   April 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. ATX3-77Q

   Plasmid

   #184249

   Purpose

   Recombinant protein expression and purification. Encodes ataxin-3 full length with 3 UIMs and 77Q in the Poly-Q track fused with His-Tag and TEV cleavage sequence (N-terminal)

   Depositor

   Sandra Macedo Ribeiro

   Article

   Figueiredo et al Cells. 2022 Jun 19;11(12). pii: cells111

   Insert

   Ataxin-3 full length with 3 UIMs and 77Q in the Poly-Q track (ATXN3 Synthetic, Human)
   

   Tags

   6x His-Tag and TEV cleavage site

   Expression

   Bacterial

   Mutation

   Codon optimization for protein expression in BL2…

   Promoter

   T7 promoter

   Available Since

   Aug. 25, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. PA-DAD-dark

   Plasmid

   #53096

   Purpose

   Expresses dark mutant PA-DAD in mammalian cells, an optogenetic tool to activate endogenous diaphanous related formins in live cells using light with LOV2 in the closed conformation

   Depositor

   Ronen Zaidel-Bar, Klaus Hahn

   Article

   Rao et al Cytoskeleton (Hoboken). 2013 Jul;70(7):3

   Insert

   LOV(dark)-6aa-DAD
   

   Tags

   6x His and mVenus

   Expression

   Bacterial, Insect, and Mamm…

   Mutation

   L47F and C49S in Venus; C450M mutation in LOV2

   Available Since

   Aug. 19, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLe6Δ -hLP-mcs/(EGFP-IresPuro-hInt)

   Plasmid

   #64314

   Purpose

   chondrocyte-specific COL11A2 promoter/enhancer lentiviral reporter vector to select iChon cells

   Depositor

   Noriyuki Tsumaki

   Article

   Outani et al PLoS One. 2013 Oct 16;8(10):e77365. doi:

   Inserts

   COL11A2 promoter (COL11A2 Human)
   COL11A2 enhancer (COL11A2 Human)
   

   Use

   Lentiviral

   Tags

   EGFP and IRES-PURO

   Expression

   Mammalian

   Mutation

   N/A

   Available Since

   April 29, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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6. ATX3-77Q-R388G

   Plasmid

   #184251

   Purpose

   Recombinant protein expression and purification. Encodes ataxin-3 full length with 3 UIMs and 13Q in the Poly-Q track-R388G fused with His-Tag and TEV cleavage sequence (N-terminal)

   Depositor

   Sandra Macedo Ribeiro

   Article

   Figueiredo et al Cells. 2022 Jun 19;11(12). pii: cells111

   Insert

   ataxin-3 full length with 3 UIMs and 77Q in the Poly-Q track and point mutation R388G (ATXN3 Synthetic, Human)
   

   Tags

   6x His-Tag and TEV cleavage site

   Expression

   Bacterial

   Mutation

   C-terminal codon optimization for protein expres…

   Promoter

   T7 promoter

   Available Since

   Aug. 25, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. pRCA378 - pBA904 Puro-T2A-GFP CD45 CRISPRa guide 3 (pRCA360 backbone)

   Plasmid

   #238169

   Purpose

   Lentiviral CRISPR guide vector expressing PTPRC targeting sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture

   Depositor

   Thomas Norman

   Article

   Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415

   Insert

   CD45 sgRNA CRISPRa (PTPRC Synthetic, Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   GFP

   Available Since

   June 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pTR01F/hFGFR3b-V5

   Plasmid

   #236016

   Purpose

   for PiggyBac mediated integration and stable expression of hFGFR3b protein

   Depositor

   Pavel Krejčí

   Article

   Zlinska et al Mol Ther Nucleic Acids. 2024 Nov 28;36(1

   Insert

   human FGFR3b (FGFR3 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Promoter

   truncated CMV promoter

   Available Since

   April 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTR01F/hFGFR4-V5

   Plasmid

   #236017

   Purpose

   for PiggyBac mediated integration and stable expression of hFGFR4 protein

   Depositor

   Pavel Krejčí

   Article

   Zlinska et al Mol Ther Nucleic Acids. 2024 Nov 28;36(1

   Insert

   human FGFR4 (FGFR4 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Promoter

   truncated CMV promoter

   Available Since

   April 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. Lenti-N1303K-ngRNA+14_EF1a-puroR

    Plasmid

    #207359

    Purpose

    Lentiviral transfer plasmid encoding hU6-driven expression of a ngRNA for correction of N1303K-CFTR via prime editing and EF1a-driven puromycin resistance gene.

    Depositor

    Marianne Carlon

    Article

    Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

    Insert

    N1303K-CFTR +14 ngRNA
    

    Use

    Lentiviral

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. Lenti-L227R-ngRNA+15_EF1a-puroR

    Plasmid

    #207360

    Purpose

    Lentiviral transfer plasmid encoding hU6-driven expression of a ngRNA for correction of L227R-CFTR via prime editing and EF1a-driven puromycin resistance gene.

    Depositor

    Marianne Carlon

    Article

    Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

    Insert

    L227R-CFTR +15 ngRNA
    

    Use

    Lentiviral

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. ATX3 13Q- I77K Q78K W87K

    Plasmid

    #185908

    Purpose

    Expresses ataxin-3 full length with 3 UIMs and 13Q in the Poly-Q track-I77K, Q78K,W87K (N-terminal ) fused with His-Tag and TEV cleavage sequence (C-terminal).

    Depositor

    Sandra Macedo Ribeiro

    Article

    Figueiredo et al Cells. 2022 Jun 19;11(12). pii: cells111

    Insert

    ataxin-3 full length with 3 UIMs and 13Q in the Poly-Q track and point mutations I77K, Q78K and W87K (ATXN3 Synthetic, Human)
    

    Tags

    6x His-Tag and TEV cleavage site

    Expression

    Bacterial

    Mutation

    Point mutations in Atx3 gene I77K Q78K and W87K

    Available Since

    Aug. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. pKP332 (Lenti-OSK1)

    Plasmid

    #21627

    Depositor

    Tim Townes

    Article

    Chang et al Stem Cells. 2009 May . 27(5):1042-9.

    Insert

    hOCT4 - 2A - hSOX2 - 2A - hKLF4 (POU5F1, SOX2, KLF4 Porcine teschovirus-1, Human)
    

    Use

    Cre/Lox and Lentiviral

    Expression

    Mammalian

    Available Since

    Nov. 12, 2009

    Availability

    Academic Institutions and Nonprofits only

    

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14. Tet-off Full length Tau (0N4R, P301L/V337M)

    Plasmid

    #188573

    Purpose

    Dox-repressible expression of the 0N4R Tau isoform

    Depositor

    Franz-Ulrich Hartl

    Article

    Saha et al Nat Commun. 2023 Feb 2;14(1):560. doi: 1

    Insert

    0N4R Tau (MAPT Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    P301L and V337M

    Promoter

    pTight TRE

    Available Since

    Feb. 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. Lenti-CMV-MLH1dn-IRES-puroR

    Plasmid

    #207354

    Purpose

    Lentiviral transfer plasmid containing CMV-driven expression cassette encoding MLH1dn for prime editing (PE4 and PE5 systems).

    Depositor

    Marianne Carlon

    Article

    Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

    Insert

    MutL homolog 1 (MLH1 Human)
    

    Use

    Lentiviral

    Mutation

    Δ754-756 dominant negative mutant

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. Lenti-N1303K-tevopreQ1-epegRNA+13C>G_EF1a-puroR (PBS 14 - RTT 18)

    Plasmid

    #207356

    Purpose

    Lentiviral transfer plasmid encoding hU6-driven expression of a N1303K-CFTR correcting prime editing guide (epegRNA) and EF1a-driven puromycin resistance gene.

    Depositor

    Marianne Carlon

    Article

    Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

    Insert

    N1303K-CFTR + 13 C>G tevopreq1-prime editing guide RNA (epegRNA)
    

    Use

    Lentiviral

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. PGL4.11-COL1A1mSMAD

    Plasmid

    #230917

    Purpose

    Tested the COL1A1 promoter activity after abolition of the proximal SMAD binding sites in the promoter.

    Depositor

    Avi Rosenberg

    Article

    Yang et al Lab Invest. 2024 May;104(5):100336. doi:

    Insert

    Human COL1A1 promoter with mutant SMAD binding sequence (COL1A1 Human)
    

    Use

    Luciferase

    Tags

    Luciferase-luc2p

    Expression

    Bacterial and Mammalian

    Mutation

    COL1A1 promoter with mutant potential SMAD bindin…

    Promoter

    COL1A1

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. Lenti-L227R-tevopreQ1-epegRNA+13C>A_EF1a-puroR (PBS 10 - RTT 19)

    Plasmid

    #207357

    Purpose

    Lentiviral transfer plasmid encoding hU6-driven expression of a L227R-CFTR correcting prime editing guide (epegRNA) and EF1a-driven puromycin resistance gene.

    Depositor

    Marianne Carlon

    Article

    Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

    Insert

    L227R-CFTR + 13 C>A tevopreq1-prime editing guide RNA (epegRNA)
    

    Use

    Lentiviral

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pTR01F/hFGFR1b-V5

    Plasmid

    #236012

    Purpose

    for PiggyBac mediated integration and stable expression of hFGFR1b protein

    Depositor

    Pavel Krejčí

    Article

    Zlinska et al Mol Ther Nucleic Acids. 2024 Nov 28;36(1

    Insert

    human FGFR1b (FGFR1 Human)
    

    Tags

    V5/His

    Expression

    Mammalian

    Promoter

    truncated CMV promoter

    Available Since

    Aug. 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. PGL4.11-COL1A1mTEAD

    Plasmid

    #230916

    Purpose

    Comparing with wild type COL1A1 promoter, tested whether mutant TEAD binding sites changed the promoter activity.

    Depositor

    Avi Rosenberg

    Article

    Yang et al Lab Invest. 2024 May;104(5):100336. doi:

    Insert

    Human COL1A1 promoter with mutant TEAD elements (COL1A1 Human)
    

    Use

    Luciferase

    Tags

    Luciferase- luc2p

    Expression

    Bacterial and Mammalian

    Mutation

    mutant potential TEAD bind elements AGGAAT to CTG…

    Promoter

    COL1A1

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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