We narrowed to 1,040 results for: Sri

1. pLV-hCCND1-T286A-HA

   Plasmid

   #174155

   Purpose

   Lentiviral vector expressing HA-tagged human cyclin D1 with T286A mutation

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   CCND1 (CCND1 Human)
   

   Use

   Lentiviral

   Tags

   hemagglutinin (HA)

   Expression

   Mammalian

   Mutation

   A>G at base 856 (Thr>Ala at amino acid 286)

   Promoter

   EF1A

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pcDNA4-deltaH-AMBRA1-3xFLAG

   Plasmid

   #174158

   Purpose

   Vector for expression of 3xFLAG-tagged truncated AMBRA1 that cannot bind DDB1 (aa 1-34 deleted)

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA1 (AMBRA1 Human)
   

   Use

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Missing aa 1-34

   Promoter

   CMV

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pKHH030_sgRB1#1

   Plasmid

   #174144

   Purpose

   Lentiviral vector expressing a sgRNA against the human RB1 gene

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   RB1 (RB1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pKHH030_sgAMBRA1#2

   Plasmid

   #174147

   Purpose

   Lentiviral vector expressing a sgRNA against the human AMBRA1 gene

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA (AMBRA1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pKHH030_sgAMBRA1#1

   Plasmid

   #174146

   Purpose

   Lentiviral vector expressing a sgRNA against the human AMBRA1 gene

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA (AMBRA1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pCG_SARS-CoV2/bat-CoV RaTG13 E C-V5-tag

   Plasmid

   #179977

   Purpose

   Mammalian expression vector for SARS-CoV-2 E or bat RaTG13 E, V5-tagged (SARS-CoV-2 E and RaTG13 E have the same amino acid sequence and codon optimized sequence).

   Depositor

   Konstantin Sparrer

   Article

   Hayn et al Cell Rep. 2021 May 18;35(7):109126.

   Insert

   SARS-CoV-2 E (E Synthetic)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   human codon-optimized

   Promoter

   Available since

   Feb. 7, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. pPB-AMBRA1-501*-3xFLAG

   Plasmid

   #174160

   Purpose

   PiggyBac vector to stably express 3xFLAG-tagged AMBRA1 truncated at amino acid 501

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA1 (AMBRA1 Human)
   

   Use

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Missing aa 501-1208

   Promoter

   EF1A

   Available since

   Sept. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pPB-AMBRA1-217*-3xFLAG

   Plasmid

   #174161

   Purpose

   PiggyBac vector to stably express 3xFLAG-tagged AMBRA1 truncated at amino acid 217

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA1 (AMBRA1 Human)
   

   Use

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Missing aa 217-1208

   Promoter

   EF1A

   Available since

   Sept. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. KRD9_HBA1(HBA1reg-HBB)

   Plasmid

   #232402

   Purpose

   AAV production plasmid for HBA1 UTRs vector from Fig. 3 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank HBA1 cassette. HAs are ~400bp each.

   Depositor

   Kyle Cromer, Matthew Porteus

   Article

   Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10

   Insert

   Hemoglobin Subunit Alpha 1 (HBA1 Human)
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   April 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. KRD2_HBA1(HBA1reg-UbC-GFP)

    Plasmid

    #232401

    Purpose

    AAV production plasmid for HBA1 WGR vector from Fig. 1 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBA1 UTRs flank UbC-GFP cassette; GFP is followed by BGH polyA. HAs are ~400bp each.

    Depositor

    Kyle Cromer, Matthew Porteus

    Article

    Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10

    Insert

    Hemoglobin Subunit Alpha 1 (HBA1 Human)
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. Nav1.5_1-2linker411-717_PPSYtoAASA1960-1996

    Plasmid

    #187732

    Purpose

    Express a chimera of the Nav1.5 linker between the first and second transmembrane domain with the motif surrounding PPSY; residues 1974-1977 PPSY mutated to AASA

    Depositor

    Sandra Gabelli

    Article

    Wright et al J Biol Chem. 2024 Mar;300(3):105715. doi

    Insert

    Nav1.5 1,2linker residues 411-717 and Nav1.5 residues 1960-1996 PPSY mutated to AASA (SCN5A Human)
    

    Use

    Tags

    His-TEV

    Expression

    Bacterial

    Mutation

    deletion of residues 1-410 and 718-1959 and 1997-…

    Promoter

    Available since

    Oct. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pCW-codon optimized catalytically inactive PHGDH

    Plasmid

    #154903

    Purpose

    Expresses codon optimized catalytically inactive PHGDH in mammalian cells

    Depositor

    Michael Pacold

    Article

    Ngo et al Cancer Discov. 2020 Sep;10(9):1352-1373.

    Insert

    Phosphoglycerate dehydrogenase (PHGDH Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Three mutations: D175N, R236K, H283A

    Promoter

    TRE

    Available since

    July 30, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. KRD22_HBA1(HBA1reg-HBB-longHAs)

    Plasmid

    #232403

    Purpose

    AAV production plasmid for HBA1 long HAs vector from Figs. 3-6 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank full HBA1-2A-YFP cassette. HAs are ~900bp

    Depositor

    Kyle Cromer, Matthew Porteus

    Article

    Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10

    Inserts

    Hemoglobin Subunit Alpha 1 (HBA1 Human)
    Human Hemoglobin Subunit Beta (HBB Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pCG_SARS-CoV2 NSP7/bat-CoV RaTG13 C-V5-tag

    Plasmid

    #179974

    Purpose

    Mammalian expression vector for SARS-CoV-2 Nsp7 or bat RaTG13 Nsp7, V5-tagged (SARS-CoV-2 Nsp7 and RaTG13 Nsp7 have the same amino acid sequence and codon optimized sequence).

    Depositor

    Konstantin Sparrer

    Article

    Hayn et al Cell Rep. 2021 May 18;35(7):109126.

    Insert

    SARS-CoV-2 Nsp7 (ORF1ab Synthetic)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    human codon-optimized

    Promoter

    Available since

    Feb. 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pSG5-hPXR-K62Q

    Plasmid

    #67766

    Purpose

    Expression hPXR mutant K62Q in Mammalian Cells

    Depositor

    Sridhar Mani

    Insert

    human pregnane X receptor (PXR) (NR1I2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    lysine 62 to Glutamine

    Promoter

    SV40

    Available since

    July 22, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pSG5-hPXR-K62R

    Plasmid

    #67765

    Purpose

    Expression hPXR mutant K62R in Mammalian Cells

    Depositor

    Sridhar Mani

    Insert

    human pregnane X receptor (PXR) (NR1I2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    lysine 62 to Arginine

    Promoter

    SV40

    Available since

    July 22, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pCMX-hPXR-K62R

    Plasmid

    #67768

    Purpose

    Expression hPXR mutant K62R in Mammalian Cells

    Depositor

    Sridhar Mani

    Insert

    human pregnane X receptor (PXR) (NR1I2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    lysine 62 to Arginine

    Promoter

    CMV

    Available since

    July 22, 2015

    Availability

    Academic Institutions and Nonprofits only

18. pCMX-hPXR-K62Q

    Plasmid

    #67767

    Purpose

    Expression hPXR mutant K62Q in Mammalian Cells

    Depositor

    Sridhar Mani

    Insert

    human pregnane X receptor (PXR) (NR1I2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    lysine 62 to Glutamine

    Promoter

    CMV

    Available since

    July 22, 2015

    Availability

    Academic Institutions and Nonprofits only

19. 1552 pcDNA3 HA gamma adaptin 1

    Plasmid

    #10712

    Depositor

    William Sellers

    Insert

    Gamma adaptin 1 (AP1G1 Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Jan. 5, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pCDNA3-hPXR-FL-T248E

    Plasmid

    #41617

    Depositor

    Sridhar Mani

    Insert

    hPXR-FL-T248E (NR1I2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    N10D and T248E

    Promoter

    CMV

    Available since

    March 11, 2013

    Availability

    Academic Institutions and Nonprofits only