We narrowed to 18,031 results for: Mut

1. Rat Alpha2 delta-1 mutMIDAS pMT2

   Plasmid

   #58730

   Purpose

   expression of rat alpha2 delta-1 with MIDAS site mutations in mammalian cells

   Depositor

   Annette Dolphin

   Article

   Hoppa et al Nature. 2012 May 13;486(7401):122-5. doi

   Insert

   alpha2 delta-1 (Cacna2d1 Rat)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   MIDAS site mutations (D259VSGS to AVAGA)

   Promoter

   SV40

   Available Since

   Oct. 3, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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2. pICE-EGFP-FLAG-Ku70siR-Mut6E

   Plasmid

   #46962

   Purpose

   For constitutive or doxycycline-inducible expression of mutant human Ku70 unable to bind DNA and resistant to siRNA. Confers resistance to puro. Use T-REx cells for doxycycline-inducible expression.

   Depositor

   Steve Jackson

   Article

   Britton et al J Cell Biol. 2013 Jul 29.

   Insert

   Ku70 (XRCC6 Human)
   

   Use

   Tags

   GFP-FLAG

   Expression

   Mammalian

   Mutation

   Mut6E corresponding to K282E K287E T300E K331E K3…

   Promoter

   CMV Tet

   Available Since

   Aug. 20, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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3. pMXS-IRES-Blast POLE1 C-ISCmut

   Plasmid

   #160804

   Purpose

   Express C-terminal ISC mutant POLE1

   Depositor

   Richard Possemato

   Article

   Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

   Insert

   POLE1 C-ISCmut (POLE Human)
   

   Use

   Retroviral

   Tags

   3xFLAG

   Expression

   Mutation

   shPOLE_1 and shPOLE2 resistant, C2221S, C2224S, C…

   Promoter

   Available Since

   Oct. 30, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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4. mCherry-C1 SNX9 KR mutant K267N R327N

   Plasmid

   #161994

   Purpose

   Mammalian expression vector containing a PIP-binding defective mutant of SNX9. Also contains mCherry tag

   Depositor

   David Bryant

   Article

   Roman-Fernandez et al Nat Commun. 2018 Nov 28;9(1):5041. doi:

   Insert

   SNX9 (Snx9 Mouse)
   

   Use

   Tags

   mCherry

   Expression

   Mammalian

   Mutation

   K267N R327N

   Promoter

   Available Since

   Jan. 12, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. FL MALT1 Catalytic Mutant in pET29b-Strep

   Plasmid

   #48969

   Purpose

   Expresses Full length catalytic mutant MALT1 in e.coli

   Depositor

   Guy Salvesen

   Article

   Hachmann et al Biochem J. 2012 Apr 1;443(1):287-95. doi

   Insert

   MALT1 isoform A (MALT1 Human)
   

   Use

   Tags

   His and Strep

   Expression

   Bacterial

   Mutation

   Catalytic Mutant C464A

   Promoter

   T7

   Available Since

   Nov. 6, 2013

   Availability

   Academic Institutions and Nonprofits only

6. pMSCV PIG IMP-1-long-mut

   Plasmid

   #21661

   Depositor

   David Bartel

   Article

   Mayr et al Cell. 2009 Aug 21. 138(4):673-84.

   Insert

   IGF-II mRNA-binding protein 1 (IGF2BP1 Human)
   

   Use

   Retroviral

   Tags

   GFP and IRES

   Expression

   Mammalian

   Mutation

   mutated let-7 binding sites.

   Promoter

   Available Since

   July 28, 2009

   Availability

   Academic Institutions and Nonprofits only

   

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7. BDS-2 3x MUT (p53 binding site)

   Plasmid

   #16516

   Depositor

   Bert Vogelstein

   Article

   Hermeking et al Mol Cell. 1997 Dec . 1(1):3-11.

   Insert

   p53 binding site (SFN Human)
   

   Use

   Tags

   Luciferase

   Expression

   Mammalian

   Mutation

   Mutant p53 binding sites

   Promoter

   Available Since

   March 28, 2008

   Availability

   Academic Institutions and Nonprofits only

8. LB595 (Bcl-2 promoter CRE mut)

   Plasmid

   #15243

   Depositor

   Linda Boxer

   Article

   Heckman et al Oncogene. 2002 May 30. 21(24):3898-908.

   Insert

   B-cell lymphoma/leukemia-2 (BCL2 Human)
   

   Use

   Luciferase

   Tags

   Luciferase

   Expression

   Bacterial

   Mutation

   Mutated CRE site at -1537 changed from GTGACGTTA …

   Promoter

   Available Since

   Aug. 1, 2007

   Availability

   Academic Institutions and Nonprofits only

9. pcDNA3.1-FLAG-Dicer-5'-pocket mutant

   Plasmid

   #51368

   Depositor

   Narry Kim

   Article

   Park et al Nature. 2011 Jul 13;475(7355):201-5. doi

   Insert

   Dicer (DICER1 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   5' pocket mutant (R778A, R780A, R811A, H982A…

   Promoter

   CMV

   Available Since

   March 31, 2014

   Availability

   Academic Institutions and Nonprofits only

10. pIS1 DICER1 long-mut-let-7

    Plasmid

    #21651

    Depositor

    David Bartel

    Article

    Mayr et al Cell. 2009 Aug 21. 138(4):673-84.

    Insert

    Dicer 1 (DICER1 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    Mutant let-7 microRNA binding sites

    Promoter

    Available Since

    July 22, 2009

    Availability

    Academic Institutions and Nonprofits only

    

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11. pLEX-FHH-MAPKAP1RBD/Triple Mutant

    Plasmid

    #120711

    Purpose

    Expresses Flag-HA-6xHIS-MAPKAP1 RBD Triple Mutant fusion protein in mammalian cells & for virus production

    Depositor

    Paul Khavari

    Article

    Kovalski et al Mol Cell. 2019 Jan 4. pii: S1097-2765(18

    Insert

    MAPKAP1 RBD
    

    Use

    Lentiviral

    Tags

    Flag-HA-6xHIS

    Expression

    Mammalian

    Mutation

    Amino acids 279-353, K307A, K310A, R312L

    Promoter

    CMV

    Available Since

    Jan. 30, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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12. pGL3-BASIC- ARHGAP29 Mutant PROMOTER

    Plasmid

    #104156

    Purpose

    luciferase reporter with ARHGAP29 mutant promoter

    Depositor

    Marius Sudol

    Article

    Qiao et al Cell Rep. 2017 May 23;19(8):1495-1502. d

    Insert

    ARHGAP29 promoter (ARHGAP29 Human)
    

    Use

    Luciferase

    Tags

    luciferase

    Expression

    Mammalian

    Mutation

    delete two TEAD binding sites

    Promoter

    ARHGAP29

    Available Since

    Jan. 2, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pIS1 DICER1 long-mut-all

    Plasmid

    #21653

    Depositor

    David Bartel

    Article

    Mayr et al Cell. 2009 Aug 21. 138(4):673-84.

    Insert

    Dicer 1 (DICER1 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    Mutated let-7 and miR103/107 microRNA binding sit…

    Promoter

    Available Since

    July 22, 2009

    Availability

    Academic Institutions and Nonprofits only

    

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14. pGL2 p15 4xSBR2 Mut 3' box

    Plasmid

    #15708

    Depositor

    Joan Massague

    Article

    Gomis et al Cancer Cell. 2006 Sep . 10(3):203-14.

    Insert

    p15 4xSBR2 (CDKN2B Human)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    Mutant 3' box. The 3' box contains the …

    Promoter

    Available Since

    Sept. 7, 2007

    Availability

    Academic Institutions and Nonprofits only

15. pGL3-Control-E2F-3'UTR-Mut

    Plasmid

    #21171

    Depositor

    Joshua Mendell

    Article

    O'Donnell et al Nature. 2005 Jun 9. 435(7043):839-43.

    Insert

    E2F 3'UTR Mutant (E2F1 Human)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    2 miR binding sites mutated. Changed from GCACTTT…

    Promoter

    Available Since

    June 9, 2009

    Availability

    Academic Institutions and Nonprofits only

16. XE116 pCS2+-E1A mut CBP

    Plasmid

    #16695

    Depositor

    Randall Moon

    Article

    Takemaru et al J Cell Biol. 2000 Apr 17. 149(2):249-54.

    Insert

    pCS2+-EIA mut CBP
    

    Use

    Xenopus expression

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Sept. 13, 2012

    Availability

    Academic Institutions and Nonprofits only

17. pIS1 IMP-1 long-mut-let-7

    Plasmid

    #21642

    Depositor

    David Bartel

    Article

    Mayr et al Cell. 2009 Aug 21. 138(4):673-84.

    Insert

    IGF-II mRNA-binding protein 1 (IGF2BP1 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    Mutant let-7 microRNA binding sites

    Promoter

    Available Since

    July 28, 2009

    Availability

    Academic Institutions and Nonprofits only

    

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18. pIS1 Cyclin D2 long-mut-miR15/16

    Plasmid

    #21647

    Depositor

    David Bartel

    Article

    Mayr et al Cell. 2009 Aug 21. 138(4):673-84.

    Insert

    Cyclin D2 long-mut-miR15/16 (CCND2 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    Mutant miR15/16 microRNA binding sites

    Promoter

    Available Since

    July 22, 2009

    Availability

    Academic Institutions and Nonprofits only

    

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19. pcDNA4/HisMaxB-YAP2-1st WW mutant

    Plasmid

    #18998

    Depositor

    Marius Sudol

    Article

    Oka et al J Biol Chem. 2008 Oct 10;283(41):27534-2

    Insert

    Yes-kinase associated protein (YAP1 Human)
    

    Use

    Tags

    His

    Expression

    Mammalian

    Mutation

    Tryptophan 199 changed to Alanine, and Proline 2…

    Promoter

    Available Since

    Sept. 8, 2008

    Availability

    Academic Institutions and Nonprofits only

20. pLV-PGK-SNAP-MDMUT-SOX2

    Plasmid

    #115688

    Purpose

    Constitutive expression of a SOX2 protein tagged with SNAP-tag and a non-functional mitotic degron (MDMUT) for control

    Depositor

    David Suter

    Article

    Deluz et al Genes Dev. 2016 Nov 15;30(22):2538-2550.

    Insert

    SNAP-MDMUT-SOX2
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Sept. 18, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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