We narrowed to 164,287 results for: HTT

1. HTT delta-exon1

   Plasmid

   #162274

   Purpose

   Baculovirus and mammalian expression

   Depositor

   Cheryl Arrowsmith

   Insert

   HTT (HTT Human)
   

   Use

   Baculovirus expresssion

   Tags

   10xHis-Flag

   Expression

   Mammalian

   Mutation

   Promoter

   CMV and P10

   Available Since

   Dec. 17, 2020

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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2. USPQ-HTT-TALEN1

   Plasmid

   #92243

   Purpose

   TALEN targeting upstream of HTT gene (KKR), forms obligate heterodimer with USPQ-HTT-TALEN2

   Depositor

   Mahmoud Pouladi

   Article

   Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

   Insert

   TALEN
   

   Use

   TALEN

   Tags

   Expression

   Mutation

   Promoter

   CMV

   Available Since

   Feb. 26, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. USPQ-HTT-TALEN2

   Plasmid

   #92244

   Purpose

   TALEN targeting upstream of HTT gene (ELD), forms obligate heterodimer with USPQ-HTT-TALEN1

   Depositor

   Mahmoud Pouladi

   Article

   Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

   Insert

   TALEN
   

   Use

   TALEN

   Tags

   Expression

   Mutation

   Promoter

   CMV

   Available Since

   Feb. 26, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. pWalium Htt19Q-mCherry

   Plasmid

   #201248

   Purpose

   allows the expression of the insert in Drosophila melanogaster

   Depositor

   Pedro Domingos

   Article

   Branco-Santos et al Hum Mol Genet. 2017 Oct 1;26(19):3763-37

   Insert

   Huntingtin (HTT Human)
   

   Use

   Tags

   Expression

   Insect

   Mutation

   Promoter

   Available Since

   Aug. 1, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. Cox1-FusXTBE-RightTALE

   Plasmid

   #196503

   Purpose

   Expresses right-side TALE–DddAtox C term half cox1-FusXTBE in zebrafish

   Depositor

   Stephen Ekker

   Article

   Sabharwal et al CRISPR J. 2021 Dec;4(6):799-821. doi: 10

   Insert

   IDH2 MTS-cox1 right TALE-G1397 DddA-C-UGI-SV40 polyA
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   Available Since

   March 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. Cox3-FusXTBE-RightTALE

   Plasmid

   #196505

   Purpose

   Expresses right-side TALE–DddAtox C term half cox3-FusXTBE in zebrafish

   Depositor

   Stephen Ekker

   Article

   Sabharwal et al CRISPR J. 2021 Dec;4(6):799-821. doi: 10

   Insert

   IDH2 MTS-cox3 right TALE-G1397 DddA-C-UGI-SV40 polyA
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   Available Since

   March 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. tl1-FusXTBE-RightTALE

   Plasmid

   #196507

   Purpose

   Expresses left-side TALE–DddAtox N term half tl1-FusXTBE in zebrafish

   Depositor

   Stephen Ekker

   Article

   Sabharwal et al CRISPR J. 2021 Dec;4(6):799-821. doi: 10

   Insert

   IDH2 MTS-tl1 right TALE-G1397 DddA-C-UGI-SV40 polyA
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   Available Since

   March 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV2ss-U6-sgHTT1-7sk-sgCas9

   Plasmid

   #190900

   Purpose

   AAV-KamiCas9 vector expressing sgGFP and human HTT sgRNAs

   Depositor

   Nicole Déglon

   Article

   Duarte et al Mol Ther Methods Clin Dev. 2023 Mar 27;2

   Insert

   sgRNA (HTT spCas9, Human)
   

   Use

   AAV and CRISPR

   Tags

   Expression

   Mutation

   Promoter

   U6 and 7sk

   Available Since

   March 27, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTWIN1-His6-Ssp-Httex1-7Q

   Plasmid

   #84347

   Purpose

   Expression of the human Huntingtin Exon1 protein containing 7Q in E.coli

   Depositor

   Hilal Lashuel

   Article

   Vieweg et al J Biol Chem. 2016 Jun 3;291(23):12074-86

   Insert

   Huntingtin Exon 1 (HTT Human)
   

   Use

   Tags

   N-terminal His6-tagged intein Ssp

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available Since

   Dec. 19, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. DSPQ-HTT-TALEN2 BSD

    Plasmid

    #92246

    Purpose

    TALEN targeting downstream of HTT gene (ELD) with Blasticidin selection, forms obligate heterodimer with DSPQ-HTT-TALEN1 ZEO. TALEN: NN, HD, NN, NN, HD, NG, NN, NI, NN, NN, HD, NI, NN, HD, NI, NN

    Depositor

    Mahmoud Pouladi

    Article

    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

    Insert

    TALEN
    

    Use

    TALEN

    Tags

    Expression

    Mutation

    Promoter

    CAG

    Available Since

    Feb. 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. DSPQ-HTT-TALEN1 ZEO

    Plasmid

    #92245

    Purpose

    TALEN targeting downstream of HTT gene (KKR) with Blasticidin selection, forms obligate heterodimer with DSPQ-HTT-TALEN2 BSD. TALEN: HD, NI, NN, HD, NG, NG, HD, HD, NG, HD, NI, NN, HD, HD, NN, HD

    Depositor

    Mahmoud Pouladi

    Article

    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

    Insert

    TALEN
    

    Use

    TALEN

    Tags

    Expression

    Mutation

    Promoter

    CAG

    Available Since

    April 8, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pAAVss-U6-sgHTT51-7sk-Cas9

    Plasmid

    #190901

    Purpose

    AAV-KamiCas9 vector expressing sgGFP and mouse HTT sgRNA

    Depositor

    Nicole Déglon

    Article

    Duarte et al Mol Ther Methods Clin Dev. 2023 Mar 27;2

    Insert

    sgRNA (Htt Mouse)
    

    Use

    AAV and CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6 and 7sk

    Available Since

    March 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pTWIN1-His6-Ssp-Httex1-43Q

    Plasmid

    #84352

    Purpose

    Expression of the human Huntingtin Exon1 protein containing 43Q in E.coli

    Depositor

    Hilal Lashuel

    Article

    Vieweg et al J Biol Chem. 2016 Jun 3;291(23):12074-86

    Insert

    Huntingtin Exon 1 (HTT Human)
    

    Use

    Tags

    N-terminal Ssp intein (His-tagged)

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available Since

    Dec. 19, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pTWIN1-His6-Ssp-Httex1-23Q

    Plasmid

    #84349

    Purpose

    Expression of the human Huntingtin Exon1 protein containing 23Q in E.coli

    Depositor

    Hilal Lashuel

    Article

    Vieweg et al J Biol Chem. 2016 Jun 3;291(23):12074-86

    Insert

    Huntingtin Exon 1 (HTT Human)
    

    Use

    Tags

    N-terminal Ssp intein (His-tagged)

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available Since

    Jan. 24, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pENTR221-H1-sgHTT1-U6-sgGFP2-7SK-sgCas9

    Plasmid

    #87917

    Purpose

    Gateway cloning

    Depositor

    Nicole Déglon

    Article

    Merienne et al Cell Rep. 2017 Sep 19;20(12):2980-2991.

    Insert

    sgHTT1, sgGFP2, shCas9
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    H1, U6, 7SK

    Available Since

    Sept. 19, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pTWIN1-His6-Ssp-Httex1-29Q

    Plasmid

    #84350

    Purpose

    Expression of the human Huntingtin Exon1 protein containing 29Q in E.coli

    Depositor

    Hilal Lashuel

    Article

    Vieweg et al J Biol Chem. 2016 Jun 3;291(23):12074-86

    Insert

    Huntingtin Exon 1 (HTT Human)
    

    Use

    Tags

    N-terminal Ssp intein (His-tagged)

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available Since

    Jan. 18, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pTWIN1-His6-Ssp-Httex1-37Q

    Plasmid

    #84351

    Purpose

    Expression of the human Huntingtin Exon1 protein containing 37Q in E.coli

    Depositor

    Hilal Lashuel

    Article

    Vieweg et al J Biol Chem. 2016 Jun 3;291(23):12074-86

    Insert

    Huntingtin Exon 1 (HTT Human)
    

    Use

    Tags

    N-terminal Ssp intein (His-tagged)

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available Since

    Dec. 19, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pTWIN1-His6-Ssp-Httex1-15Q

    Plasmid

    #84348

    Purpose

    Expression of the human Huntingtin Exon1 protein containing 15Q in E.coli

    Depositor

    Hilal Lashuel

    Article

    Vieweg et al J Biol Chem. 2016 Jun 3;291(23):12074-86

    Insert

    Huntingtin Exon1 (HTT Human)
    

    Use

    Tags

    N-terminal Ssp intein (His-tagged)

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available Since

    Dec. 19, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pRS416 CUP1pro-Htt103QdeltaP125-134-YFP

    Plasmid

    #224882

    Purpose

    Low copy plasmid for inducible yeast expression of the Htt exon 1 construct without the first 10 amino acids of the proline-rich region (125-134) tagged with YFP using copper.

    Depositor

    Paul Herman

    Insert

    Htt103QdeltaP125-134 (HTT Human)
    

    Use

    Tags

    YFP

    Expression

    Yeast

    Mutation

    deltaP125-134

    Promoter

    CUP1

    Available Since

    Oct. 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pRS416 CUP1pro-Htt103QdeltaP135-170-YFP

    Plasmid

    #224878

    Purpose

    Low copy plasmid for inducible yeast expression of the Htt exon 1 construct without the last 36 amino acids of the proline-rich region (135-170) tagged with YFP using copper.

    Depositor

    Paul Herman

    Insert

    Htt103QdeltaP135-170 (HTT Human)
    

    Use

    Tags

    YFP

    Expression

    Yeast

    Mutation

    deltaP135-170

    Promoter

    CUP1

    Available Since

    Oct. 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge