We narrowed to 164,223 results for: HTT

1. pComb3HTT

   Plasmid

   #63900

   Purpose

   Backbone of pComb3H containing TT Fab (light and heavy chains) against tetanus toxin, used as phage display/expression control.

   Depositor

   Carlos Barbas

   Article

   Barbas et al Methods, A companion to Methods in Enzym

   Insert

   TT Fab
   

   Use

   Phage display

   Tags

   geneIII

   Expression

   Bacterial

   Mutation

   Promoter

   lacZ

   Available Since

   July 21, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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2. pFRT-TODestFLAGHAhTTP

   Plasmid

   #48738

   Purpose

   Expresses hTTP

   Depositor

   Thomas Tuschl

   Insert

   TTP (ZFP36 Human)
   

   Use

   Tags

   FLAG, HA, and V5

   Expression

   Mammalian

   Mutation

   Promoter

   CMV, 2x Tet

   Available Since

   June 13, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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3. 61427-sgHtt_10

   Plasmid

   #157861

   Purpose

   Expresses a sgRNA targeting mouse Htt promoter for gene activation using the SAM system

   Depositor

   Xinyu Zhao

   Article

   Shen et al Nat Neurosci. 2019 Mar;22(3):386-400. do

   Insert

   Htt (Htt Mouse)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Feb. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. 61427-sgHtt_6

   Plasmid

   #157860

   Purpose

   Expresses a sgRNA targeting mouse Htt promoter for gene activation using the SAM system

   Depositor

   Xinyu Zhao

   Article

   Shen et al Nat Neurosci. 2019 Mar;22(3):386-400. do

   Insert

   Htt (Htt Mouse)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Feb. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCDNA-hTtAgo

   Plasmid

   #104383

   Purpose

   human codon optimized TtAgo; pCDNA3 vector backbone, mammalian expression

   Depositor

   David Segal

   Article

   O'Geen et al PLoS One. 2018 Mar 27;13(3):e0193818. do

   Insert

   hTtAgo
   

   Use

   Tags

   3XFlag, Nucleoplasmin NLS, and SV40 NLS

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available Since

   April 3, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. MR015-PHOX2BRightTALEN_NN

   Plasmid

   #49449

   Purpose

   Right TALEN for PHOX2B with NN

   Depositor

   Bruce Conklin

   Article

   Miyaoka et al Nat Methods. 2014 Mar;11(3):291-3. doi:

   Insert

   TALEN
   

   Use

   TALEN

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Dec. 30, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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7. MR015-PHOX2BRightTALEN_NK

   Plasmid

   #49478

   Purpose

   Right TALEN for PHOX2B with NK

   Depositor

   Bruce Conklin

   Article

   Miyaoka et al Nat Methods. 2014 Mar;11(3):291-3. doi:

   Insert

   TALEN
   

   Use

   TALEN

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Dec. 12, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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8. pTreTight-Htt94Q-CFP

   Plasmid

   #23966

   Depositor

   Nico Dantuma

   Article

   Maynard et al Proc Natl Acad Sci U S A. 2009 Aug 18. 1

   Insert

   N-terminal fragment Huntingtin Q94 (HTT Human)
   

   Use

   Tags

   CFP

   Expression

   Mammalian

   Mutation

   94 polyQ repeat

   Promoter

   Available Since

   April 15, 2010

   Availability

   Academic Institutions and Nonprofits only

   

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9. pJOP-HTT-HR65Q

   Plasmid

   #92249

   Purpose

   HTT donor DNA with 65Q for homologous recombination-mediated gene modification

   Depositor

   Mahmoud Pouladi

   Article

   Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

   Insert

   HTT donor DNA (HTT Human)
   

   Use

   Precisionx hr targeting vector

   Tags

   Expression

   Mutation

   Barcode of wobble bases to prevent TALEN cleaving…

   Promoter

   Available Since

   Feb. 26, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. pJOP-HTT-HR45Q

    Plasmid

    #92248

    Purpose

    HTT donor DNA with 45Q for homologous recombination-mediated gene modification

    Depositor

    Mahmoud Pouladi

    Article

    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

    Insert

    HTT donor DNA (HTT Human)
    

    Use

    Precisionx hr targeting vector

    Tags

    Expression

    Mutation

    Barcode of wobble bases to prevent TALEN cleaving…

    Promoter

    Available Since

    Feb. 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pJOP-HTT-HR81Q

    Plasmid

    #92250

    Purpose

    HTT donor DNA with 81Q for homologous recombination-mediated gene modification

    Depositor

    Mahmoud Pouladi

    Article

    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

    Insert

    HTT donor DNA (HTT Human)
    

    Use

    Precisionx hr targeting vector

    Tags

    Expression

    Mutation

    Barcode of wobble bases to prevent TALEN cleaving…

    Promoter

    Available Since

    Feb. 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pJOP-HTT-HR30Q

    Plasmid

    #92247

    Purpose

    HTT donor DNA with 30Q for homologous recombination-mediated gene modification

    Depositor

    Mahmoud Pouladi

    Article

    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

    Insert

    HTT donor DNA (HTT Human)
    

    Use

    Precisionx hr targeting vector

    Tags

    Expression

    Mutation

    Barcode of wobble bases to prevent TALEN cleaving…

    Promoter

    Available Since

    Feb. 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. p3xFLAG-CMV10-hTti1

    Plasmid

    #30213

    Depositor

    Noboru Mizushima

    Article

    Kaizuka et al J Biol Chem. 2010 Jun 25. 285(26):20109-

    Insert

    Tel2 interacting protein 1 (TTI1 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    July 7, 2011

    Availability

    Academic Institutions and Nonprofits only

14. pJOP-HTT-HR18Q

    Plasmid

    #87228

    Purpose

    HTT HR arms with 18 CAG repeats and piggyBac selection cassette

    Depositor

    Mahmoud Pouladi

    Article

    Xu et al Stem Cell Reports. 2017 Feb 21. pii: S22

    Insert

    1.7kb HTT 5' homology arm, 2.5kb HTT 3' homology arm
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a driving selection cassette

    Available Since

    July 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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15. pX335 HTT sgRNA-a

    Plasmid

    #87201

    Purpose

    pX335 vector encoding SpCas9n and a chimeric guide RNA targeting exon 1 of HTT

    Depositor

    Mahmoud Pouladi

    Article

    Xu et al Stem Cell Reports. 2017 Feb 21. pii: S22

    Insert

    HTT (HTT Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available Since

    July 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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16. pX335 HTT sgRNA-b

    Plasmid

    #87200

    Purpose

    pX335 vector encoding SpCas9n and a chimeric guide RNA targeting 5' UTR of HTT

    Depositor

    Mahmoud Pouladi

    Article

    Xu et al Stem Cell Reports. 2017 Feb 21. pii: S22

    Insert

    HTT (HTT Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available Since

    July 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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17. HTT delta-exon1

    Plasmid

    #162274

    Purpose

    Baculovirus and mammalian expression

    Depositor

    Cheryl Arrowsmith

    Insert

    HTT (HTT Human)
    

    Use

    Baculovirus expresssion

    Tags

    10xHis-Flag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV and P10

    Available Since

    Dec. 17, 2020

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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18. USPQ-HTT-TALEN1

    Plasmid

    #92243

    Purpose

    TALEN targeting upstream of HTT gene (KKR), forms obligate heterodimer with USPQ-HTT-TALEN2

    Depositor

    Mahmoud Pouladi

    Article

    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

    Insert

    TALEN
    

    Use

    TALEN

    Tags

    Expression

    Mutation

    Promoter

    CMV

    Available Since

    Feb. 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. USPQ-HTT-TALEN2

    Plasmid

    #92244

    Purpose

    TALEN targeting upstream of HTT gene (ELD), forms obligate heterodimer with USPQ-HTT-TALEN1

    Depositor

    Mahmoud Pouladi

    Article

    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7

    Insert

    TALEN
    

    Use

    TALEN

    Tags

    Expression

    Mutation

    Promoter

    CMV

    Available Since

    Feb. 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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20. pWalium Htt19Q-mCherry

    Plasmid

    #201248

    Purpose

    allows the expression of the insert in Drosophila melanogaster

    Depositor

    Pedro Domingos

    Article

    Branco-Santos et al Hum Mol Genet. 2017 Oct 1;26(19):3763-37

    Insert

    Huntingtin (HTT Human)
    

    Use

    Tags

    Expression

    Insect

    Mutation

    Promoter

    Available Since

    Aug. 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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