We narrowed to 3,386 results for: psin

1. pHR-mCh-Cry2WT_NLS

   Plasmid

   #221925

   Purpose

   Expression of SV40 nuclear localization signal (NLS) fused to optogenetic protein mCh-Cry2WT

   Depositor

   Daniel Bose

   Insert

   SV40 NLS
   

   Use

   Lentiviral

   Tags

   mCherry

   Expression

   Mammalian

   Mutation

   insertion of SV40 NLS

   Promoter

   Available since

   July 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. AAV-SYN-eGFP-oPRE

   Plasmid

   #218681

   Purpose

   AAV vector plasmid expressing enhanced green fluorescent protein (eGFP) under the human synapsin (SYN) promoter. It also contains an optimised and truncated version of WPRE as a regulatory element.

   Depositor

   Bart Nieuwenhuis

   Insert

   eGFP
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   May 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-hSyn-hChR2(H134R)-mCherry

   Plasmid

   #26976

   Purpose

   AAV expression of humanized ChR2 with H134R mutation fused to mCherry, for optogenetic excitation

   Depositor

   Karl Deisseroth

   Has Service

   AAV5, AAV8, and AAV9

   Insert

   hChR2(H134R)
   

   Use

   AAV

   Tags

   mCherry

   Expression

   Mammalian

   Mutation

   H134R

   Promoter

   hSyn

   Available since

   Feb. 4, 2011

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-synp-F-synaptophysin-jRGECO1a

   Plasmid

   #102997

   Purpose

   Expresses synaptophysin fused jRGECO1a under the synapsin promoter

   Depositor

   David Cox

   Insert

   Synaptophysin-jRGECO1a
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. hSyn-DIO-somBiPOLES-eGFP

   Plasmid

   #192584

   Purpose

   AAV-vector for bidirectional optogenetic manipulation of Cre-positive neurons

   Depositor

   Simon Wiegert

   Insert

   somBiPOLES
   

   Use

   AAV

   Tags

   soma-targeting motif from Kv2.1 channel

   Expression

   Mammalian

   Mutation

   Promoter

   human synapsin

   Available since

   Dec. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-synp-F-synaptophysin-GCaMP6f

   Plasmid

   #102996

   Purpose

   Expresses synaptophysin fused GCaMP6f under the synapsin promoter

   Depositor

   David Cox

   Insert

   Synaptophysin-GCaMP6f
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-CaMKIIa-eNpHR 3.0-EYFP

   Plasmid

   #26971

   Purpose

   AAV expression of eNpHR 3.0 fused to EYFP driven by CaMKIIa promoter for optogenetic inhibition

   Depositor

   Karl Deisseroth

   Has Service

   AAV1 and AAV9

   Insert

   eNpHR 3.0
   

   Use

   AAV

   Tags

   EYFP

   Expression

   Mammalian

   Mutation

   Trafficking Signal (TS) ER Export Signal

   Promoter

   CaMKIIa

   Available since

   Feb. 4, 2011

   Availability

   Academic Institutions and Nonprofits only

   

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8. CRY2-OCRL

   Plasmid

   #79566

   Purpose

   expression of CRY2PHR fused to inositol 5-phosphatase domain of OCRL

   Depositor

   Olof Idevall-Hagren

   Insert

   OCRL (OCRL Human)
   

   Use

   Tags

   CRY2 (photolyase homology region domain of Arabid…

   Expression

   Mammalian

   Mutation

   aa 234_539

   Promoter

   CMV

   Available since

   Aug. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

9. pLenti-CaMKIIa-eNpHR 3.0-EYFP

   Plasmid

   #26970

   Purpose

   3rd gen lentiviral expression of eNpHR 3.0 fused to EYFP driven by CaMKIIa promoter for optogenetic inhibition

   Depositor

   Karl Deisseroth

   Insert

   eNpHR 3.0
   

   Use

   Lentiviral

   Tags

   EYFP

   Expression

   Mammalian

   Mutation

   Trafficking Signal (TS), ER Export Signal (FCYENE)

   Promoter

   CaMKIIa

   Available since

   Jan. 27, 2011

   Availability

   Academic Institutions and Nonprofits only

   

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10. hSyn-Aion-ts-mScarlet-ER

    Plasmid

    #192577

    Purpose

    AAV-vector for optogenetic long-term silencing of neurons

    Depositor

    Simon Wiegert

    Insert

    Aion
    

    Use

    AAV

    Tags

    ts-mScarlet-ER

    Expression

    Mammalian

    Mutation

    T59S, E83N, E90Q, E101S, V117R, E123S, C128A,D156…

    Promoter

    human synapsin

    Available since

    Dec. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. BIRC1A

    Plasmid

    #42400

    Purpose

    Bacterial expression for structure determination; may not be full ORF

    Depositor

    Nicola Burgess-Brown

    Insert

    BIRC1A (NAIP Human)
    

    Use

    Tags

    His6-TEV

    Expression

    Bacterial

    Mutation

    See Comments

    Promoter

    Available since

    March 18, 2013

    Availability

    Academic Institutions and Nonprofits only

12. pAAV.CaMKIIa.ChETA(E123T/H134R)-eYFP.WPRE.hGH

    Plasmid

    #100050

    Purpose

    AAV expression of humanized ChR2 with E123T/H134R mutations fused to EYFP driven by CaMKIIa promoter for optogenetic activation

    Depositor

    Karl Deisseroth

    Has Service

    AAV9

    Insert

    hChR2(E123T/H134R)
    

    Use

    AAV

    Tags

    EYFP

    Expression

    Mammalian

    Mutation

    humanized, E123T/H134R

    Promoter

    CaMKIIa

    Available since

    Jan. 31, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV-Ef1a-DIO C1V1 (t/t)-TS-mCherry (PV2670)

    Plasmid

    #100061

    Purpose

    AAV expression of ChR1-VChR1 Chimera fused to mCherry driven by Ef1a promoter

    Depositor

    Karl Deisseroth

    Has Service

    AAV9

    Insert

    ChR1-VChR1 Chimera
    

    Use

    AAV

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    E122T and E162T

    Promoter

    EF1a

    Available since

    Jan. 31, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH

    Plasmid

    #100049

    Purpose

    AAV expression of humanized ChR2 with E123T/H134R mutations fused to EYFP driven by hSynap promoter for optogenetic activation

    Depositor

    Karl Deisseroth

    Has Service

    AAV9

    Insert

    hChR2(E123T/H134R)
    

    Use

    AAV

    Tags

    EYFP

    Expression

    Mammalian

    Mutation

    humanized, E123T/H134R

    Promoter

    hSynap

    Available since

    Jan. 31, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. AAV-GFAPp-PiGM-Iq(mCherry)

    Plasmid

    #221609

    Purpose

    A recombinant AAV2 plasmid encoding the PiGM-Iq system with CRY2PHR, CIBN and mCherry as expression marker. GFAP promoter for astrocyte-selective expression.

    Depositor

    John Lin

    Insert

    PiGM-Iq (D387A, mCherry)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    RGS2 1-53 truncation, CRYPHR D387A

    Promoter

    GFAP promoter

    Available since

    Aug. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. hSyn-Aion-mKate2

    Plasmid

    #192574

    Purpose

    AAV-vector for optogenetic long-term silencing of neurons

    Depositor

    Simon Wiegert

    Insert

    Aion
    

    Use

    AAV

    Tags

    mKate2

    Expression

    Mammalian

    Mutation

    T59S, E83N, E90Q, E101S, V117R, E123S, C128A,D156…

    Promoter

    human synapsin

    Available since

    Dec. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-hSyn-FLEX-TeLC-P2A-EYFP-WPRE

    Plasmid

    #135391

    Purpose

    Cre-dependent Tetanus toxin light chain construct for conditional silencing of neurons.

    Depositor

    Fan Wang

    Insert

    TeLC-P2A-EYFP
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hSynapsin

    Available since

    Dec. 18, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAAV-CaMKIIa-hChR2(H134R)-mCherry

    Plasmid

    #26975

    Purpose

    AAV expression of humanized ChR2(H134R) fused to mCherry driven by CaMKIIa promoter for optogenetic excitation

    Depositor

    Karl Deisseroth

    Has Service

    AAV Retrograde, AAV1, AAV5, and AAV9

    Insert

    hChR2(H134R)
    

    Use

    AAV

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    H134R

    Promoter

    CaMKIIa

    Available since

    Feb. 4, 2011

    Availability

    Academic Institutions and Nonprofits only

    

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19. pRho-Cre

    Plasmid

    #13779

    Depositor

    Connie Cepko

    Article

    Matsuda et al Proc Natl Acad Sci U S A. 2007 Jan 16;10

    Insert

    Rhodopsin promoter-Cre
    

    Use

    Cre/Lox

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 20, 2007

    Availability

    Academic Institutions and Nonprofits only

    

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20. AAV-GFAPp-PiGM-Iq(D387A mCherry)

    Plasmid

    #221608

    Purpose

    A recombinant AAV2 plasmid encoding the light insensitive PiGM-Iq system with CRY2PHR(D387A), CIBN and mCherry as expression marker. GFAP promoter for astrocyte-selective expression.

    Depositor

    John Lin

    Insert

    PiGM-Iq (mCherry)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    RGS2 1-53 truncation

    Promoter

    GFAP promoter

    Available since

    Sept. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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