We narrowed to 18,786 results for: tec

1. Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

   Pooled Library

   #75315

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

   Pooled Library

   #75313

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

3. Compact mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

   Pooled Library

   #136479

   Purpose

   Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

   Depositor

   Jonathan Weissman

   Article

   Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

4. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

   Pooled Library

   #136478

   Purpose

   Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

   Depositor

   Jonathan Weissman

   Article

   Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

5. CHyMErA Exon-deletion hgRNA Library

   Pooled Library

   #155200

   Purpose

   Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

6. CHyMErA Paralog&Dual-targeting hgRNA Library

   Pooled Library

   #155199

   Purpose

   Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

7. US0hisB-pyrF-

   Bacterial Strain

   #12614

   Depositor

   Scot Wolfe

   Article

   Meng et al Nat Biotechnol. 2005 Aug . 23(8):988-94.

   Bacterial Resistance

   Tetracycline

   Available since

   Sept. 26, 2006

   Availability

   Academic Institutions and Nonprofits only

8. CLM24 ∆lpxM

   Bacterial Strain

   #132780

   Purpose

   CLM24 strain with lpxM deletion

   Depositor

   Michael Jewett

   Article

   Stark et al Sci Adv. 2021 Feb 3;7(6). pii: 7/6/eabe9

   Bacterial Resistance

   None

   Available since

   Nov. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

9. TP997

   Bacterial Strain

   #13055

   Depositor

   Anthony Poteete

   Article

   Poteete et al BioTechniques. 2006 Sept. 41(3):261-264

   Bacterial Resistance

   Ampicillin and spectinomycin

   Species

   Tn1696

   Available since

   Sept. 26, 2006

   Availability

   Academic Institutions and Nonprofits only

10. Human Base Editing Sensor Library

    Pooled Library

    #179218

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

11. Mouse Base Editing Sensor Library

    Pooled Library

    #179217

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

12. ALL-PAM sensor Library

    Pooled Library

    #179219

    Purpose

    10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

13. C321.∆A T7RNAP

    Bacterial Strain

    #182776

    Purpose

    Recoded E. coli MG1655 strain with UAG termination function removed (RF1 is deleted); T7RNAP cassette genomically inserted

    Depositor

    Michael Jewett

    Article

    Perez et al Biotechnol J. 2021 Dec 11:e2100330. doi:

    Bacterial Resistance

    Spectinomycin

    Available since

    April 18, 2023

    Availability

    Academic Institutions and Nonprofits only

14. MW005 (bacterial strain)

    Bacterial Strain

    #24545

    Depositor

    Colin Dolphin

    Article

    Westenberg et al BMC Biotechnol. 2010 Mar 29. 10(1):27.

    Bacterial Resistance

    Streptomycin

    Available since

    Sept. 13, 2010

    Availability

    Academic Institutions and Nonprofits only

15. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

    Pooled Library

    #89640

    Purpose

    Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

    Depositor

    Wensheng Wei

    Article

    Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 17, 2017

    Availability

    Academic Institutions and Nonprofits only

16. CROPseq-iT7 Human CRISPR Knockout Pooled Library (Brunello)

    Pooled Library

    #223064

    Purpose

    Optical pooled genome-scale CRISPR KO screening using Nuclear In-Situ Sequencing (NIS-Seq)

    Depositor

    Jonathan Schmid-Burgk

    Article

    Fandrey et al Nat Biotechnol. 2024 Dec 19. doi: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 23, 2025

    Availability

    Academic Institutions and Nonprofits only

17. C321.∆A ompT- rne- endA- lon-

    Bacterial Strain

    #182775

    Purpose

    Recoded E. coli MG1655 strain with UAG termination function removed (RF1 is deleted); ompT, rne, endA, lon inactivated

    Depositor

    Michael Jewett

    Article

    Perez et al Biotechnol J. 2021 Dec 11:e2100330. doi:

    Bacterial Resistance

    Ampicillin

    Available since

    April 18, 2023

    Availability

    Academic Institutions and Nonprofits only

18. C321.∆A T7RNAP ompT- rne-

    Bacterial Strain

    #182777

    Purpose

    Recoded E. coli MG1655 strain with UAG termination function removed (RF1 is deleted); T7RNAP cassette genomically inserted; ompT and rne inactivated

    Depositor

    Michael Jewett

    Article

    Perez et al Biotechnol J. 2021 Dec 11:e2100330. doi:

    Bacterial Resistance

    Spectinomycin

    Available since

    April 18, 2023

    Availability

    Academic Institutions and Nonprofits only

19. DHIP1

    Bacterial Strain

    #226851

    Purpose

    Expresses HIP1 methyltransferase to methylate plasmids for delivery to cyanobacteria

    Depositor

    David Nielsen

    Article

    Kamoku et al Biotechnol Prog. 2025 Jan 23:e3518. doi:

    Bacterial Resistance

    Streptomycin

    Species

    Escherichia coli

    Available since

    Nov. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

20. C321.∆A ompT- rne- endA-

    Bacterial Strain

    #182774

    Purpose

    Recoded E. coli MG1655 strain with UAG termination function removed (RF1 is deleted); ompT, rne, endA inactivated

    Depositor

    Michael Jewett

    Article

    Perez et al Biotechnol J. 2021 Dec 11:e2100330. doi:

    Bacterial Resistance

    Ampicillin

    Available since

    April 18, 2023

    Availability

    Academic Institutions and Nonprofits only