We narrowed to 3,313 results for: cgas

1. pTRIP-SFFV-EGFP-NLS-FLAG-cGAS

   Plasmid

   #127659

   Purpose

   Over-express EGFP-NLS-FLAG-cGAS

   Depositor

   Nicolas Manel

   Article

   Gentili et al Cell Rep. 2019 Feb 26;26(9):2377-2393.e1

   Insert

   cGAS (CGAS Human)
   

   Use

   Lentiviral

   Tags

   EGFP-NLS-Flag

   Expression

   Mutation

   Promoter

   Available since

   July 12, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pHW533 (Peft-3::cGAL-N::let-858 3'UTR)

   Plasmid

   #107132

   Purpose

   cGAL-N driver under the control of C. elegans eft-3 promoter

   Depositor

   Paul Sternberg

   Article

   Wang et al Proc Natl Acad Sci U S A. 2018 Mar 26. p

   Insert

   NLS::cGAL(DBD)::gp41-1-N-intein
   

   Use

   Tags

   Expression

   Worm

   Mutation

   Promoter

   C. elegans eft-3 promoter

   Available since

   March 29, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pHW531 (Peft-3::cGAL-C::let-858 3'UTR)

   Plasmid

   #107136

   Purpose

   cGAL-C driver under the control of C. elegans eft-3 promoter

   Depositor

   Paul Sternberg

   Article

   Wang et al Proc Natl Acad Sci U S A. 2018 Mar 26. p

   Insert

   NLS::gp41-1-C-intein::cGAL(AD)
   

   Use

   Tags

   Expression

   Worm

   Mutation

   Promoter

   C. elegans eft-3 promoter

   Available since

   March 29, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pHW530 (Prab-3::cGAL-N::let-858 3'UTR)

   Plasmid

   #107131

   Purpose

   cGAL-N driver under the control of C. elegans rab-3 promoter

   Depositor

   Paul Sternberg

   Article

   Wang et al Proc Natl Acad Sci U S A. 2018 Mar 26. p

   Insert

   NLS::cGAL(DBD)::gp41-1-N-intein
   

   Use

   Tags

   Expression

   Worm

   Mutation

   Promoter

   C. elegans rab-3 promoter

   Available since

   March 29, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pHW522 (Prab-3::cGAL-C::let-858 3'UTR)

   Plasmid

   #107130

   Purpose

   cGAL-C driver under the control of C. elegans rab-3 promoter

   Depositor

   Paul Sternberg

   Article

   Wang et al Proc Natl Acad Sci U S A. 2018 Mar 26. p

   Insert

   NLS::gp41-1-C-intein::cGAL(AD)
   

   Use

   Tags

   Expression

   Worm

   Mutation

   Promoter

   C. elegans rab-3 promoter

   Available since

   March 29, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pTRIP-CMV-Puro-2A-NLS-FLAG-cGAS

   Plasmid

   #127656

   Purpose

   Over-express NLS-FLAG-cGAS

   Depositor

   Nicolas Manel

   Article

   Gentili et al Cell Rep. 2019 Feb 26;26(9):2377-2393.e1

   Insert

   cGAS (CGAS Human)
   

   Use

   Lentiviral

   Tags

   Flag

   Expression

   Mutation

   Promoter

   Available since

   July 11, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pRRL-gRNA(anti-cGAS)-Cas9-Puro

   Plasmid

   #130908

   Purpose

   gRNA targeting human cGAS; Cas9 insert; Puromycin selection marker

   Depositor

   Jonathan Kagan

   Article

   Barnett et al Cell. 2019 Mar 7;176(6):1432-1446.e11. d

   Insert

   Cas9
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Aug. 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pcDNA3.1-Hygro(+)-PSTCD-cGAS-delta DBD

   Plasmid

   #102606

   Purpose

   Mammalian expression of mutant cGAS with deletion of DNA binding domain fused to PSTCD tag

   Depositor

   Nicolas Manel

   Article

   Gentili et al Science. 2015 Sep 11;349(6253):1232-6. d

   Insert

   cGAS (CGAS Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   delta K173-I220 and delta H390-C405

   Promoter

   CMV

   Available since

   Jan. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAH36 (Pmyo-2::cGAL-C::let-858 3'UTR)

   Plasmid

   #107135

   Purpose

   cGAL-C driver under the control of C. elegans myo-2 promoter

   Depositor

   Paul Sternberg

   Article

   Wang et al Proc Natl Acad Sci U S A. 2018 Mar 26. p

   Insert

   NLS::gp41-1-C-intein::cGAL(AD)
   

   Use

   Tags

   Expression

   Worm

   Mutation

   Promoter

   C. elegans myo-2 promoter

   Available since

   March 29, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAH35 (Pmyo-2::cGAL-N::let-858 3'UTR)

    Plasmid

    #107134

    Purpose

    cGAL-N driver under the control of C. elegans myo-2 promoter

    Depositor

    Paul Sternberg

    Article

    Wang et al Proc Natl Acad Sci U S A. 2018 Mar 26. p

    Insert

    NLS::cGAL(DBD)::gp41-1-N-intein
    

    Use

    Tags

    Expression

    Worm

    Mutation

    Promoter

    C. elegans myo-2 promoter

    Available since

    March 29, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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11. pLenti-CMV-cGAS R71/75E C396/7A-HA

    Plasmid

    #130920

    Purpose

    Expresses human cGAS with R71/75E and C396/397A point mutations; Puromycin selection marker

    Depositor

    Jonathan Kagan

    Article

    Barnett et al Cell. 2019 Mar 7;176(6):1432-1446.e11. d

    Insert

    human cGAS R71/75E C396/7A
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    aa 71 and 75 mutated to glutamate; aa 396 and 397…

    Promoter

    CMV

    Available since

    Aug. 27, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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12. pRRL-mouse cGAS #1-gRNA-Cas9-Puro

    Plasmid

    #186890

    Purpose

    gRNA targeting mouse cGAS (with Cas9 insert)

    Depositor

    Jonathan Kagan

    Article

    Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

    Insert

    Cas9 (Cgas Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pRRL-mouse cGAS #2-gRNA-Cas9-Puro

    Plasmid

    #186891

    Purpose

    gRNA targeting mouse cGAS (with Cas9 insert)

    Depositor

    Jonathan Kagan

    Article

    Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

    Insert

    Cas9 (Cgas Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pTRE3G-FLAG-human cGAS N-T2A-deltaN-HA

    Plasmid

    #186886

    Purpose

    Doxycycline-dependent expression of human cGAS gene in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

    Insert

    Human cGAS with T2A ribosome skipping sequences between N-terminus (1-159 a.a.) and C-terminus (160-522 a.a.) (Adamts1 Human)
    

    Use

    Retroviral

    Tags

    FLAG and HA

    Expression

    Mutation

    Insertion of T2A ribosome skipping site

    Promoter

    TRE3G

    Available since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLenti-CMV-FLAG-orangutan cGASdeltaN-OMM

    Plasmid

    #186889

    Purpose

    Expression of orangutan cGAS gene in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Mosallanejad et al Sci Immunol. 2023 Jan 20;8(79):eabp9765.

    Insert

    Orangutan cGAS truncation mutant (158-521 a.a.) with N-terminal FLAG tag and C-terminal MAVS transmembrane domain fusion (CGAS Synthetic, Pongo abelii)
    

    Use

    Lentiviral

    Tags

    FLAG

    Expression

    Mutation

    N-terminal truncation, MAVS transmembrane domain …

    Promoter

    CMV

    Available since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pTRIP-CMV-GFP-FLAG-cGAS E225A-D227A

    Plasmid

    #86674

    Purpose

    Expresses catalytically-inactive GFP-cGAS after lentiviral transduction. Can be used to monitor nuclear envelope rupture events.

    Depositor

    Nicolas Manel

    Article

    Raab et al Science. 2016 Apr 15;352(6283):359-62. d

    Insert

    GFP-FLAG-cGAS E225A/D227A
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    April 18, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCDH-cGAS-E225A D227A-mCherry2-EF1-Puro

    Plasmid

    #132771

    Purpose

    Interacts with cytoplasmic DNA. Useful for identifying sites of nuclear envelope rupture.

    Depositor

    Jan Lammerding

    Article

    Denais et al Science. 2016 Apr 15;352(6283):353-8. do

    Insert

    Cyclic GMP-AMP synthase (CGAS Human)
    

    Use

    Lentiviral

    Tags

    mCherry2

    Expression

    Mammalian

    Mutation

    E225A D227A

    Promoter

    Available since

    Jan. 3, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. pTRIP-SFFV-EGFP-FLAG-cGAS E225A/D227A

    Plasmid

    #127662

    Purpose

    Over-express catalytically inactive EGFP-FLAG-cGAS E225A/D227A

    Depositor

    Nicolas Manel

    Article

    Gentili et al Cell Rep. 2019 Feb 26;26(9):2377-2393.e1

    Insert

    cGAS (CGAS Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    E225A/D227A

    Promoter

    Available since

    July 12, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. pTRIP-CMV-mCherry-FLAG-cGAS E225A/D227A

    Plasmid

    #127657

    Purpose

    Over-express catalytically inactive mCherry-FLAG-cGAS E225A/D227A

    Depositor

    Nicolas Manel

    Article

    Gentili et al Cell Rep. 2019 Feb 26;26(9):2377-2393.e1

    Insert

    cGAS (CGAS Human)
    

    Use

    Lentiviral

    Tags

    Flag and mCherry

    Expression

    Mutation

    E225A/D227A

    Promoter

    Available since

    July 12, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAH34 (Phsp-16.41::cGAL-N::let-858 3'UTR)

    Plasmid

    #107133

    Purpose

    cGAL-N driver under the control of C. elegans hsp-16.41 promoter

    Depositor

    Paul Sternberg

    Article

    Wang et al Proc Natl Acad Sci U S A. 2018 Mar 26. p

    Insert

    NLS::cGAL(DBD)::gp41-1-N-intein
    

    Use

    Tags

    Expression

    Worm

    Mutation

    Promoter

    C. elegans hsp-16.41 promoter

    Available since

    March 29, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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