We narrowed to 10,414 results for: 158

1. G1397 DddAtox-N–SaKKH-Cas9(D10A)

   Plasmid

   #157839

   Purpose

   expresses split DddAtox-Cas9 construct in mammalian cells

   Depositor

   David Liu

   Article

   Mok et al Nature. 2020 Jul 8. pii: 10.1038/s41586-

   Insert

   G1397 DddAtox-N–SaKKH-Cas9(D10A)–UGI–SV40 NLS
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Aug. 4, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pDONR221 NLRP1 S1213A

   Plasmid

   #166824

   Purpose

   Gateway pDONR vector containing NLRP1 with the P1214R patient mutation (no stop codon)

   Depositor

   Daniel Bachovchin

   Article

   Hollingsworth et al Nature. 2021 Mar 17. pii: 10.1038/s41586

   Insert

   NLRP1 (NLRP1 Human)
   

   Use

   Gateway shuttling vector

   Tags

   Expression

   Mutation

   S1213A

   Promoter

   Available since

   March 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pQTEV-MAPRE1

   Plasmid

   #31589

   Depositor

   Konrad Buessow

   Article

   Bussow et al Microb Cell Fact. 2005 Jul 5;4:21. doi:

   Insert

   microtubule-associated protein, RP/EB family, member 1 (MAPRE1 Human)
   

   Use

   Tags

   His and TEV

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   March 22, 2013

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. sgCTRL-hygro

   Plasmid

   #199639

   Purpose

   sgRNA control; induces CAS9 cutting in an intergenic region

   Depositor

   William Hahn

   Article

   So et al JCI Insight. 2022 Oct 10;7(19):e158755.

   Insert

   N/A
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   May 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pMT2-MEKK3-K392A

   Plasmid

   #21585

   Depositor

   John Kyriakis

   Article

   Chadee et al Mol Cell Biol. 2002 Feb . 22(3):737-49.

   Insert

   mitogen-activated protein kinase kinase kinase 3 (MAP3K3 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Lysine 392 to Arginine

   Promoter

   Available since

   Nov. 24, 2009

   Availability

   Academic Institutions and Nonprofits only

6. pscALPS-SIV-AGM-TAN1 vpr

   Plasmid

   #115819

   Purpose

   Encodes codon optimized 3xFLAG-SIVAGM Vpr (TAN1) (U58991) with repaired premature stop codon and puromycin resistance protein

   Depositor

   Jeremy Luban

   Article

   Yurkovetskiy et al Nat Microbiol. 2018 Dec;3(12):1354-1361.

   Insert

   SIVAGM Vpr (TAN1)
   

   Use

   Lentiviral

   Tags

   3x-FLAG

   Expression

   Mutation

   Promoter

   SFFV

   Available since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pLentiCRISPR sgHAL

   Plasmid

   #102315

   Purpose

   genetic depletion of HAL

   Depositor

   David Sabatini

   Article

   Kanarek et al Nature. 2018 Jul 11. pii: 10.1038/s41586

   Insert

   sgHAL (HAL Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. MigR1-Flag-TRIB1

   Plasmid

   #131158

   Purpose

   Retroviral expression of flag-tagged mouse TRIB1

   Depositor

   Warren Pear, Karen Keeshan

   Article

   Dedhia et al Blood. 2010 Aug 26;116(8):1321-8. doi: 1

   Insert

   Trib1 (Trib1 Mouse)
   

   Use

   Retroviral

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 8, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pLentiCRISPR sgFTCD_1

   Plasmid

   #102312

   Purpose

   genetic depletion of FTCD

   Depositor

   David Sabatini

   Article

   Kanarek et al Nature. 2018 Jul 11. pii: 10.1038/s41586

   Insert

   sgFTCD_1 (FTCD Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pLentiCRISPR sgFTCD_2

    Plasmid

    #102313

    Purpose

    genetic depletion of FTCD

    Depositor

    David Sabatini

    Article

    Kanarek et al Nature. 2018 Jul 11. pii: 10.1038/s41586

    Insert

    sgFTCD_2 (FTCD Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. tdiRFP-BFP reporter

    Plasmid

    #190184

    Purpose

    The cre-activatable fluorescence reporter

    Depositor

    Toshiro Sato

    Article

    Ohta et al Nature. 2022 Jul 7. pii: 10.1038/s41586-

    Inserts

    tdiRFP
    TagBFP2
    

    Use

    Tags

    Expression

    Bacterial and Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 12, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pEE485

    Plasmid

    #231158

    Purpose

    T-DNA encoding TRV2 with mobile gRNA targeting SlPDS

    Depositor

    Daniel Voytas

    Article

    Liu et al Proc Natl Acad Sci U S A. 2024 Sep 24;12

    Insert

    mobile gRNA targeting SlPDS
    

    Use

    Tags

    Expression

    Plant

    Mutation

    Promoter

    PEBV sub-genomic

    Available since

    March 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pcDNA3.1-myc-GFP-TNRC6A-SD-WT

    Plasmid

    #215897

    Purpose

    Expression of TNRC6A-silencing domain (SD)

    Depositor

    Kumiko Ui-Tei

    Article

    Munakata et al Genes (Basel). 2021 Feb 13;12(2):271. do

    Insert

    TNRC6A (TNRC6A Human)
    

    Use

    Tags

    myc-GFP

    Expression

    Mammalian

    Mutation

    contain aa1224-1709

    Promoter

    Available since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pcDNA3.1-myc-GFP-TNRC6A-SD-CIM1-WT

    Plasmid

    #215898

    Purpose

    Expression of TNRC6A-CIM1 domain

    Depositor

    Kumiko Ui-Tei

    Article

    Munakata et al Genes (Basel). 2021 Feb 13;12(2):271. do

    Insert

    TNRC6A (TNRC6A Human)
    

    Use

    Tags

    myc-GFP

    Expression

    Mammalian

    Mutation

    contain aa1224-1528

    Promoter

    Available since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pcDNA3.1-myc-GFP-TNRC6A-SD-CIM2-WT

    Plasmid

    #215899

    Purpose

    Expression of TNRC6A-CIM2 domain

    Depositor

    Kumiko Ui-Tei

    Article

    Munakata et al Genes (Basel). 2021 Feb 13;12(2):271. do

    Insert

    TNRC6A (TNRC6A Human)
    

    Use

    Tags

    myc-GFP

    Expression

    Mammalian

    Mutation

    contain aa1529-1709

    Promoter

    Available since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. psiCHECK-1-miR-376a1(5p)-WT

    Plasmid

    #215875

    Purpose

    This plasmid encodes luciferase which has microRNA binding sites in 3'UTR for detecting the microRNA silencing activity.

    Depositor

    Kumiko Ui-Tei

    Article

    Tian et al RNA Biol. 2020 Feb;17(2):264-280. doi: 1

    Insert

    three tandem repeats of seed-matched (SM) sequence of miR-376a1(5p)-WT (MIR376A1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. psiCHECK-1-miR-376a1(3p)-WT

    Plasmid

    #215876

    Purpose

    This plasmid encodes luciferase which has microRNA binding sites in 3'UTR for detecting the microRNA silencing activity.

    Depositor

    Kumiko Ui-Tei

    Article

    Tian et al RNA Biol. 2020 Feb;17(2):264-280. doi: 1

    Insert

    three tandem repeats of seed-matched (SM) sequence of miR-376a1(3p)-WT (MIR376A1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. psiCHECK-1-miR-589(5p)-WT

    Plasmid

    #215877

    Purpose

    This plasmid encodes luciferase which has microRNA binding sites in 3'UTR for detecting the microRNA silencing activity.

    Depositor

    Kumiko Ui-Tei

    Article

    Tian et al RNA Biol. 2020 Feb;17(2):264-280. doi: 1

    Insert

    three tandem repeats of seed-matched (SM) sequence of miR-589(5p)-WT (MIR589 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. psiCHECK-1-miR-589(3p)-WT

    Plasmid

    #215878

    Purpose

    This plasmid encodes luciferase which has microRNA binding sites in 3'UTR for detecting the microRNA silencing activity.

    Depositor

    Kumiko Ui-Tei

    Article

    Tian et al RNA Biol. 2020 Feb;17(2):264-280. doi: 1

    Insert

    three tandem repeats of seed-matched (SM) sequence of miR-589(3p)-WT (MIR589 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. psiCHECK-1-miR-376a2(3p)-WT

    Plasmid

    #215879

    Purpose

    This plasmid encodes luciferase which has microRNA binding sites in 3'UTR for detecting the microRNA silencing activity.

    Depositor

    Kumiko Ui-Tei

    Article

    Tian et al RNA Biol. 2020 Feb;17(2):264-280. doi: 1

    Insert

    three tandem repeats of seed-matched (SM) sequence of miR-376a2(3p)-WT (MIR376A2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge