We narrowed to 25,261 results for: lars

1. FUS LC-RGG1 StoG

   Plasmid

   #226610

   Purpose

   All serines in the LC domain to glycine

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC-RGG1 StoG (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   All serines to glycine in the LC domain

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. FUS LC-RGG1 TtoS

   Plasmid

   #226611

   Purpose

   All threonines in the LC domain to serine

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC-RGG1 TtoS (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   All threonine to serine in the LC domain

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. FUS LC-RGG1 QtoA

   Plasmid

   #226612

   Purpose

   All glutamines in the LC domain to alanine

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC-RGG1 QtoA (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   All glutamine to alanine in the LC domain

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. FUS LC-RGG1 TtoV

   Plasmid

   #226613

   Purpose

   All threonines in the LC domain to valine

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC-RGG1 TtoV (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   All threonine to valine in the LC domain

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. FUS LC-RGG1 QtoG

   Plasmid

   #226614

   Purpose

   All glutamines in the LC domain to glycine

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC-RGG1 QtoG (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   All glutamine to glycine in the LC domain

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. FUS LC-RGG1 QtoN

   Plasmid

   #226615

   Purpose

   All glutamines in the LC domain to asparagine

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC-RGG1 QtoN (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   All glutamine to asparagine in the LC domain

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. FUS LC-RGG1 QtoS

   Plasmid

   #226616

   Purpose

   All glutamines in the LC domain to serine

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC-RGG1 QtoS (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   All glutamine to serine in the LC domain

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. FUS LC noYQ_noYT

   Plasmid

   #226617

   Purpose

   T7S / Q160S double mutation

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC noYQ_noYT (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   T7S / Q160S double mutation in LC domain to remov…

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. FUS LC-RGG1 wild type

   Plasmid

   #226596

   Purpose

   Wild type sequence of FUS LC-RGG1 domains

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC-RGG1 WT (FUS Human)
   

   Use

   Tags

   6His

   Expression

   Bacterial

   Mutation

   wild type LC-RGG1

   Promoter

   T7

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. FUS LC 4QQ->AA

    Plasmid

    #226600

    Purpose

    4 glutamine pairs to alanine pairs at positions 27, 28, 92, 93, 132, 133, 157, 158

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 4QQ->AA (FUS Human)
    

    Use

    Tags

    6His

    Expression

    Bacterial

    Mutation

    4 QQ pairs replaced with AA pairs at positions 27…

    Promoter

    T7

    Available since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. FUS LC 4QQ->GG

    Plasmid

    #226601

    Purpose

    4 glutamine pairs to glycine pairs at positions 27, 28, 92, 93, 132, 133, 157, 158

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 4QQ->GG (FUS Human)
    

    Use

    Tags

    6His

    Expression

    Bacterial

    Mutation

    4 QQ pairs replaced with GG pairs at positions 27…

    Promoter

    T7

    Available since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. FUS LC 4QQ->NN

    Plasmid

    #226602

    Purpose

    4 glutamine pairs to asparagine pairs at positions 27, 28, 92, 93, 132, 133, 157, 158

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 4QQ->NN (FUS Human)
    

    Use

    Tags

    6His

    Expression

    Bacterial

    Mutation

    4 glutamine pairs to asparagine pairs at position…

    Promoter

    T7

    Available since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. p50.mALDH1A1.CD63-GFP.wpre

    Plasmid

    #226770

    Purpose

    CD63-GFP in p52 (mAldh1a backbone)

    Depositor

    Ferdinando Pucci

    Article

    Gonzalez-Callejo et al PLoS One. 2023 Feb 3;18(2):e0279400. doi

    Insert

    CD63 (CD63 )
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pcDNA4TO-SCN8A-Variant-3-IRES-mScarlet

    Plasmid

    #209411

    Purpose

    Expression of wild-type adult isoform of human SCN8A.

    Depositor

    Al George

    Article

    Vanoye et al JCI Insight. 2024 May 21;9(12):e177530.

    Insert

    SCN8A Variant 3, stabilized (SCN8A Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Modifed human HSPA5 intron 4 inserted after bp237…

    Promoter

    CMV

    Available since

    Nov. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. GFP-PODXL FBM*/PBM*

    Plasmid

    #195221

    Purpose

    Mammalian expression vector containing GFP tagged Podocalyxin. Dual mutant for HRS>AAA / lacking DTHL.

    Depositor

    Keith Mostov, David Bryant

    Article

    Bryant et al Dev Cell. 2014 Oct 27;31(2):171-87. doi:

    Insert

    PODXL (PODXL Rabbit)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Dual mutant for HRS>AAA / lacking DTHL

    Promoter

    Available since

    Sept. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pRRL-VcnTS-E1015A-E1021A

    Plasmid

    #213411

    Purpose

    Vinculin tension sensor (VcnTS) with both directionally asymmetric, force strengthening (DAFS) variant point mutations (E1015A and E1021A), in lentiviral expression vector.

    Depositor

    Brenton Hoffman

    Article

    Chirasani et al Nat Commun. 2023 Dec 14;14(1):8300. doi:

    Insert

    VcnTS-E1015A-E1021A (VCL Chicken, Synthetic)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Mutated vinculin glutamic acid 1015 and 1021 to a…

    Promoter

    CMV

    Available since

    Feb. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pMMK ENTR 1 HITI-2c ACTB

    Plasmid

    #206269

    Purpose

    ENTR Vector 1 for MultiSite Gateway assembly. Encodes HITI-2c donor for ACTB C-terminal tagging (mCherry T2A Puro) in human cells

    Depositor

    Imre Berger

    Article

    Aulicino et al Nucleic Acids Res. 2022 Jul 22;50(13):77

    Insert

    HITI-2c donor
    

    Use

    CRISPR; Multimate/gateway entr 1

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pLVX-CMV-Flag-PolB(K206A/K244A/T304I)-Puro

    Plasmid

    #177145

    Purpose

    Lentiviral vector expressing Flag-PolB(K206A/K244A/T304I) and a puromycin resistance cassette

    Depositor

    Robert Sobol

    Article

    Fang et al Nucleic Acids Res. 2019 Jul 9;47(12):626

    Insert

    PolB (POLB Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Dec. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pGEX4T3-GST-NQO1(Y128F)

    Plasmid

    #177141

    Purpose

    Bacterial vector for expression of an N-terminal GST fusion of NQO1(Y128F) with a TEV protease site located between the GST tag and NQO1(Y128F)

    Depositor

    Robert Sobol

    Article

    Fang et al Nucleic Acids Res. 2019 Jul 9;47(12):626

    Insert

    NQO1 (NQO1 Human)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Promoter

    Tac

    Available since

    Dec. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pGEX4T3-GST-PolB(L301R/V303R/V306R)

    Plasmid

    #177137

    Purpose

    Bacterial vector for expression of an N-terminal GST fusion of PolB(L301R/V303R/V306R) with a TEV protease site located between the GST tag and PolB(L301R/V303R/V306R)

    Depositor

    Robert Sobol

    Article

    Fang et al Nucleic Acids Res. 2019 Jul 9;47(12):626

    Insert

    PolB (POLB Human)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Promoter

    Tac

    Available since

    Dec. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge