We narrowed to 12,555 results for: LIC

1. pGEMHE:mTREK-1(K271Q)

   Plasmid

   #133270

   Purpose

   X. laevis expression vector. It will generate the mouse TREK-1 channel

   Depositor

   Dan Minor

   Article

   Lolicato et al Nature. 2017 Jul 20;547(7663):364-368. d

   Insert

   Potassium channel subfamily K member 2 (KCNK2, TREK-1) (Kcnk2 )
   

   Use

   Oocyte expression

   Tags

   Expression

   Mutation

   K271Q

   Promoter

   Available since

   April 24, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. pGEMHE:hTRAAK(Q258K)

   Plasmid

   #133077

   Purpose

   X. laevis expression vector. It will generate the human TRAAK channel

   Depositor

   Dan Minor

   Article

   Lolicato et al Neuron. 2014 Dec 17;84(6):1198-212. doi:

   Insert

   Potassium channel subfamily K member 2 (KCNK2, TREK-1), Q258K (Kcnk2 Mouse)
   

   Use

   Tags

   Expression

   Mutation

   Q258K

   Promoter

   T7

   Available since

   Oct. 30, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. pDONR221-kcnj11

   Plasmid

   #173139

   Purpose

   This gene was cloned into the gateway middle entry vector. It can be used for generating antisense riboprobe or gene expression using a gateway system.

   Depositor

   GuangJun Zhang

   Article

   Silic et al Dev Dyn. 2021 Sep 23. doi: 10.1002/dvdy.

   Insert

   kcnj11 (kcnj11 Zebrafish)
   

   Use

   Pcr cloning vector

   Tags

   Expression

   Mutation

   Promoter

   No promoter at 5 end; T7 promoter at 3 end.

   Available since

   Sept. 27, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. pHBS1412 GFP-TDP43 FYW-L

   Plasmid

   #118801

   Purpose

   To test the effect of sequence on nuclear body formation and splicing of full-length TDP43

   Depositor

   Rajat Rohatgi

   Article

   Schmidt et al Nat Commun. 2019 Oct 25;10(1):4890. doi:

   Insert

   TARDBP mutant (TARDBP Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   All FYW to L in CTD of full-length TDP43

   Promoter

   Available since

   Feb. 26, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAT9750-BEAR-mCherry

   Plasmid

   #162990

   Purpose

   BEAR target plasmid with split mCherry and disrupted 5' splice site

   Depositor

   Ervin Welker

   Article

   Talas et al Nat Commun. 2021 Nov 3;12(1):6353. doi:

   Insert

   mCherry split with an intron between amino acids 119-120
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Sept. 21, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. pOPTXcGMPRELUC

   Plasmid

   #68503

   Purpose

   cyclic nucleotide reporter for bacteria or plant cells

   Depositor

   Helen Irving

   Article

   Wheeler et al BMC Biotechnol. 2013 Nov 9;13:97. doi: 1

   Insert

   OPTX promoter with cGMPRE (AT1G33440 Mustard Weed)
   

   Use

   Tags

   luciferase

   Expression

   Bacterial and Plant

   Mutation

   3x cGMPRE inserted 190bp 5' of ATG (cGMPRE =…

   Promoter

   OPTX promoter with cGMPRE

   Available since

   Sept. 3, 2015

   Availability

   Academic Institutions and Nonprofits only

7. pHBS1398 [IBB-GFP-mCherry3E]-[BFP-P2A-TDP43 G368W]

   Plasmid

   #118811

   Purpose

   To test the effect of sequence on TDP43 splicing activity

   Depositor

   Rajat Rohatgi

   Article

   Schmidt et al Nat Commun. 2019 Oct 25;10(1):4890. doi:

   Insert

   TARDBP mutant (TARDBP Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   G368W in CTD of full-length TDP43

   Promoter

   Available since

   Feb. 26, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. (PM-S608E)FLAG-Cep215-FL

   Plasmid

   #106906

   Purpose

   Expresses murine phospho-mimetic CEP215 at S608

   Depositor

   Heidi Hehnly

   Article

   Colicino et al Mol Biol Cell. 2017 Dec 27. pii: mbc.E17

   Insert

   CEP215 (Cdk5rap2 Mouse)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   changed Serine-608 to Glutamic Acid

   Promoter

   CMV

   Available since

   Feb. 20, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. pPICZ:hTRAAK(G124I)

   Plasmid

   #130672

   Purpose

   P. pastoris expression vector. It will generate the human TRAAK channel (1-300) fused to a C-terminal GFP

   Depositor

   Dan Minor

   Article

   Lolicato et al Neuron. 2014 Dec 17;84(6):1198-212. doi:

   Insert

   KCNK4 (KCNK4 Human)
   

   Use

   Tags

   SNS- 3C_cleavage_site-TAAA-GFP

   Expression

   Yeast

   Mutation

   N104Q, N108Q, G124I

   Promoter

   Available since

   May 15, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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10. GST-SF3B2 R508K aa 401-550 fragment

    Plasmid

    #79674

    Purpose

    bacterial expression of GST-SF3B2 fragment (401-550) with R508L methylation site mutation

    Depositor

    Steven Clarke

    Article

    Hadjikyriacou et al J Biol Chem. 2015 May 15. pii: jbc.M115.

    Insert

    splicing factor 3b subunit 2 (SF3B2 Human)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    aa 451-550 with R508K

    Promoter

    tac

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

11. pOPTXGARE

    Plasmid

    #68542

    Purpose

    cyclic nucleotide reporter for bacteria or plant cells

    Depositor

    Helen Irving

    Article

    Wheeler et al BMC Biotechnol. 2013 Nov 9;13:97. doi: 1

    Insert

    OPTX promoter with GARE (AT1G33440 Mustard Weed)
    

    Use

    Tags

    luciferase

    Expression

    Bacterial and Plant

    Mutation

    5x GARE inserted 190 bp 5' pf ATG (GARE = ta…

    Promoter

    OPTX promoter with GARE

    Available since

    Aug. 18, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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12. pP[RS3]3'M

    Plasmid

    #53552

    Purpose

    for an easy screen of TALEN- and CRISPR/Cas9- mediated mutagenesis in Drosophila

    Depositor

    Renjie Jiao

    Article

    Yu et al Biol Open. 2014 Apr 15;3(4):271-80. doi:

    Insert

    AscI and MluI restriction enzyme sites
    

    Use

    Tags

    Expression

    Insect

    Mutation

    Promoter

    same pP[RS3]

    Available since

    Dec. 3, 2014

    Availability

    Academic Institutions and Nonprofits only

13. pPB_TRE3G_scFV-sfGFP-Kmt5cFL-CatMut

    Plasmid

    #235590

    Purpose

    Dox-inducible expression of control catalytic-mutant Kmt5c CD fused with scFV

    Depositor

    Jamie Hackett

    Article

    Policarpi et al Nat Genet. 2024 Jun;56(6):1168-1180. doi

    Insert

    Kmt5c (Kmt5c Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    NHDC182-185AAAG

    Promoter

    Available since

    April 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pLentiCRISPR-v1-sgMTHFD1

    Plasmid

    #217436

    Purpose

    Lentiviral vector expressing Cas9 and an sgRNA targeting human MTHFD1

    Depositor

    Jason Cantor

    Article

    Flickinger et al Sci Adv. 2024 Oct 4;10(40):eadq3591. doi

    Insert

    sgRNA targeting MTHFD1 (MTHFD1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Jan. 31, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLJC2-TK2-3xFLAG

    Plasmid

    #217427

    Purpose

    Lentiviral overexpression of human TK2

    Depositor

    Jason Cantor

    Article

    Flickinger et al Sci Adv. 2024 Oct 4;10(40):eadq3591. doi

    Insert

    TK2 (TK2 Human)
    

    Use

    Lentiviral

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Insert sequence is a codon-optimized gBLOCK (IDT)

    Promoter

    CMV

    Available since

    Jan. 31, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLentiCRISPR-v1-sgTYMS

    Plasmid

    #217430

    Purpose

    Lentiviral vector expressing Cas9 and an sgRNA targeting human TYMS

    Depositor

    Jason Cantor

    Article

    Flickinger et al Sci Adv. 2024 Oct 4;10(40):eadq3591. doi

    Insert

    sgRNA targeting TYMS (TYMS Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Jan. 31, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pLentiCRISPR-v1-sgTK2_4

    Plasmid

    #217431

    Purpose

    Lentiviral vector expressing Cas9 and an sgRNA targeting human TK2

    Depositor

    Jason Cantor

    Article

    Flickinger et al Sci Adv. 2024 Oct 4;10(40):eadq3591. doi

    Insert

    sgRNA 4 targeting TK2 (TK2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Jan. 31, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pLentiCRISPR-v1-sgTK2_5

    Plasmid

    #217432

    Purpose

    Lentiviral vector expressing Cas9 and an sgRNA targeting human TK2

    Depositor

    Jason Cantor

    Article

    Flickinger et al Sci Adv. 2024 Oct 4;10(40):eadq3591. doi

    Insert

    sgRNA 5 targeting TK2 (TK2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Jan. 31, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLentiCRISPR-v1-sgSHMT2

    Plasmid

    #217435

    Purpose

    Lentiviral vector expressing Cas9 and an sgRNA targeting human SHMT2

    Depositor

    Jason Cantor

    Article

    Flickinger et al Sci Adv. 2024 Oct 4;10(40):eadq3591. doi

    Insert

    sgRNA targeting SHMT2 (SHMT2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Jan. 31, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. Lenti-Nova1-GFP

    Plasmid

    #217033

    Purpose

    Overexpression of Nova in DRG neurons promotes the "mature" splicing pattern observed in CNS neurons

    Depositor

    Chaolin Zhang

    Article

    Weyn-Vanhentenryck et al Nat Commun. 2018 Jun 6;9(1):2189. doi: 1

    Insert

    Nova1 (Nova1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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