We narrowed to 4,522 results for: GCA;

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STK40 gRNA (BRDN0001147746)

Plasmid

#75626

Purpose

3rd generation lentiviral gRNA plasmid targeting human STK40

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

STK40 (STK40 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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STK40 gRNA (BRDN0001149509)

Plasmid

#75628

Purpose

3rd generation lentiviral gRNA plasmid targeting human STK40

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

STK40 (STK40 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PRKCQ gRNA (BRDN0001147386)

Plasmid

#75555

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKCQ

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKCQ (PRKCQ Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TBCK gRNA (BRDN0001148062)

Plasmid

#75565

Purpose

3rd generation lentiviral gRNA plasmid targeting human TBCK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TBCK (TBCK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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STK10 gRNA (BRDN0001149099)

Plasmid

#75488

Purpose

3rd generation lentiviral gRNA plasmid targeting human STK10

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

STK10 (STK10 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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STK10 gRNA (BRDN0001162500)

Plasmid

#75490

Purpose

3rd generation lentiviral gRNA plasmid targeting human STK10

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

STK10 (STK10 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MVK gRNA (BRDN0001145420)

Plasmid

#77407

Purpose

3rd generation lentiviral gRNA plasmid targeting human MVK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MVK (MVK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 5, 2016

Availability

Academic Institutions and Nonprofits only

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NEK8 gRNA (BRDN0001148289)

Plasmid

#76942

Purpose

3rd generation lentiviral gRNA plasmid targeting human NEK8

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

NEK8 (NEK8 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

June 28, 2016

Availability

Academic Institutions and Nonprofits only

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pMIR-31-192-193a-Reporter

Plasmid

#71874

Purpose

Mammalian expression vector for the analysis of miR-31-19α-193a activity

Depositor

Mien-Chie Hung

Article

Shen et al Nature. 2013 May 16;497(7449):383-7. doi

Insert

Binding sequence targeted by miR-31, miR192, and miR-193a-5p

Tags

firefly luciferase

Expression

Mammalian

Promoter

CMV

Available Since

May 4, 2016

Availability

Academic Institutions and Nonprofits only
tet-pLKO.1_puro_shJUND #2

Plasmid

#136583

Purpose

Expresses an inducible short hairpin targeting human JUND sequence

Depositor

Kevin Janes

Article

Pereira et al Sci Signal. 2020 Apr 14;13(627). pii: 13

Insert

shJUNDv2 (JUND Human)

Use

Lentiviral

Expression

Mammalian

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR-ACIN1-sgRNA1

Plasmid

#165925

Purpose

CRISPR-mediated gene perturbation (knock-out) of ACIN1

Depositor

Vamsi Mootha

Article

Alexis A. et al Molecular Cell

Insert

ACIN1 (ACIN1 Human)

Use

Lentiviral

Promoter

U6

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR-HK2-sgRNA1

Plasmid

#165929

Purpose

CRISPR-mediated gene perturbation (knock-out) of HK2

Depositor

Vamsi Mootha

Article

Alexis A. et al Molecular Cell

Insert

HK2 (HK2 Human)

Use

Lentiviral

Promoter

U6

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR-HK2-sgRNA2

Plasmid

#165930

Purpose

CRISPR-mediated gene perturbation (knock-out) of HK2

Depositor

Vamsi Mootha

Article

Alexis A. et al Molecular Cell

Insert

HK2 (HK2 Human)

Use

Lentiviral

Promoter

U6

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR-LUC7L2-sgRNA1

Plasmid

#165935

Purpose

CRISPR-mediated gene perturbation (knock-out) of LUC7L2

Depositor

Vamsi Mootha

Article

Alexis A. et al Molecular Cell

Insert

LUC7L2 (LUC7L2 Human)

Use

Lentiviral

Promoter

U6

Availability

Academic Institutions and Nonprofits only

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pPB.DEST-ITGB1(WT)-mRuby2

Plasmid

#215448

Purpose

Piggybac expression vector with integrin beta1 tagged with mRuby2

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

ITGB1 (ITGB1 Human)

Use

Transposon-based stable expression

Tags

mRuby2

Expression

Mammalian

Mutation

Silent mutations added to disrupt shRNA binding a…

Promoter

CAG

Available Since

May 29, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pU6_rd6_pegRNA_(PP7-C4-Q1)

Plasmid

#232433

Purpose

pegRNA with optimized 3' modifications to correct the rd6 mutation

Depositor

Gil Westmeyer

Article

Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

Insert

3'-PP7-tagged pegRNA for rd6 correction driven by human U6 promoter

Use

CRISPR

Promoter

U6

Available Since

April 10, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgSLC7A11/xCT-1

Plasmid

#161818

Purpose

knock out SLC7A11/xCT in mammalian cells

Depositor

Boyi Gan

Article

Liu et al Nat Cell Biol. 2020 Apr;22(4):476-486. d

Insert

SLC7A11 solute carrier family 7 member 11 xCT (SLC7A11 Human)

Use

CRISPR and Lentiviral

Available Since

Dec. 8, 2020

Availability

Academic Institutions and Nonprofits only

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pCMV-GenEPi

Plasmid

#140236

Purpose

Mammalian expression of Piezo1-based fluorescent force sensor GenEPi

Depositor

Periklis Pantazis

Article

Yaganoglu et al Nat Commun. 2023 Jul 19;14(1):4352. doi:

Insert

GenEPi (Piezo1-based fluorescent force sensor) (PIEZO1 Human)

Tags

GCaMP 6s RS1 EF4

Expression

Mammalian

Promoter

simian CMV IE94

Available Since

July 24, 2023

Availability

Academic Institutions and Nonprofits only

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ATP1A1_G6_T804N_v1_Dual_epegRNA_tevopreQ1

Plasmid

#187458

Purpose

Coselection for prime editing in human cells. Vector for tandem expression of ATP1A1 T804N-G6 epegRNA (tevopreQ1) with a user-specified epegRNA. pU6-tevopreq1-GG-acceptor-like plasmid

Depositor

Yannick Doyon

Article

Levesque et al Nat Commun. 2022 Oct 7;13(1):5909. doi:

Insert

ATP1A1 G6 T804N epegRNA (tevopreQ1) (ATP1A1 Human)

Use

CRISPR; Prime editing

Expression

Mammalian

Promoter

Tandem U6 promoters

Available Since

July 21, 2022

Availability

Academic Institutions and Nonprofits only

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lentiCRISPRv2-sgCTL

Plasmid

#234771

Purpose

Non Targeting Control

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Non Targeting Control sgRNA

Use

Lentiviral

Available Since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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