We narrowed to 115 results for: mutant p53

1. BDS-2 3x MUT (p53 binding site)

   Plasmid

   #16516

   Depositor

   Bert Vogelstein

   Article

   Hermeking et al Mol Cell. 1997 Dec . 1(1):3-11.

   Insert

   p53 binding site (SFN Human)
   

   Use

   Tags

   Luciferase

   Expression

   Mammalian

   Mutation

   Mutant p53 binding sites

   Promoter

   Available since

   March 28, 2008

   Availability

   Academic Institutions and Nonprofits only

2. pRRLNeo-pEF1a-p53ashL344A-mCerulean

   Plasmid

   #69580

   Purpose

   Expresses p53-L344A mutant tagged with mCerulean

   Depositor

   Galit Lahav

   Article

   Gaglia et al Proc Natl Acad Sci U S A. 2013 Sep 17;11

   Insert

   p53-L344A (TP53 Human)
   

   Use

   Lentiviral

   Tags

   mCerulean

   Expression

   Mammalian

   Mutation

   p53 L344A mutation that prevents tetramerization …

   Promoter

   EF1alpha

   Available since

   Feb. 22, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pRRLNeo-pEF1a-p53ashL344P-mCerulean

   Plasmid

   #69581

   Purpose

   Expresses p53-L344P mutant tagged with mCerulean

   Depositor

   Galit Lahav

   Article

   Gaglia et al Proc Natl Acad Sci U S A. 2013 Sep 17;11

   Insert

   p53-L344P (TP53 Human)
   

   Use

   Lentiviral

   Tags

   mCerulean

   Expression

   Mammalian

   Mutation

   p53 L344P mutation that prevents oliogomerization…

   Promoter

   EF1alpha

   Available since

   Feb. 22, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pRetroX-TRE3G-IRSp53 P428L

   Plasmid

   #221321

   Purpose

   Dox-inducible expression of IRSp53 mutant in mammalian cells by retroviral transduction

   Depositor

   Jonathan Kagan

   Article

   Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

   Insert

   IRSp53 (Baiap2 Mouse)
   

   Use

   Retroviral

   Tags

   3xFLAG

   Expression

   Mutation

   P428L

   Promoter

   TRE3G

   Available since

   July 17, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pRetroX-TRE3G-IRSp53 S269D

   Plasmid

   #221319

   Purpose

   Dox-inducible expression of IRSp53 mutant in mammalian cells by retroviral transduction

   Depositor

   Jonathan Kagan

   Article

   Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

   Insert

   IRSp53 (Baiap2 Mouse)
   

   Use

   Retroviral

   Tags

   3xFLAG

   Expression

   Mutation

   S269D

   Promoter

   TRE3G

   Available since

   July 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pCMV-Neo-Bam p53 V143A

   Plasmid

   #16435

   Depositor

   Bert Vogelstein

   Article

   Baker et al Science. 1990 Aug 24. 249(4971):912-5.

   Insert

   p53 V143A (TP53 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   V143A. Mutant cDNA from human colorectal tumor CX…

   Promoter

   Available since

   March 12, 2008

   Availability

   Academic Institutions and Nonprofits only

7. pcDNA3.1-3XHA-p53 QM

   Plasmid

   #196268

   Purpose

   Mammalian expression of 3xHA tagged p53 L25Q,Q26S,F53Q,F54S

   Depositor

   Laura Attardi

   Article

   Raj et al Mol Cell. 2022 Jul 7;82(13):2370-2384.e1

   Insert

   Trp53 QM (Trp53 Mouse)
   

   Use

   Tags

   3xHA

   Expression

   Mammalian

   Mutation

   p53 L25Q,Q26S,F53Q,F54S mutant

   Promoter

   CMV

   Available since

   March 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. NSK024 SFFV-mCherry-SG(p53R248Q.s2)SG-EGFP (FLP-IN)

   Plasmid

   #191169

   Purpose

   Expression of a sensor for p53 mutant R248Q in mammalian cells; mCherry marker, EGFP output

   Depositor

   Xiaojing Gao

   Article

   Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

   Insert

   mCherry:p53(R248Q).s2:EGFP
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   WT

   Promoter

   SFFV

   Available since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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9. pGLS3-5xHRE-p53(K164R)

   Plasmid

   #72555

   Purpose

   Hypoxia induced mutant p53. Contains the HRE from VEGF sequence (5 repeats) upstream of p53 K164R.

   Depositor

   Ester Hammond

   Article

   Leszczynska et al J Clin Invest. 2015 Jun;125(6):2385-98.

   Insert

   p53 (TP53 Human)
   

   Use

   Tags

   5XHRE

   Expression

   Mammalian

   Mutation

   K164R

   Promoter

   E1B minimal promoter

   Available since

   March 9, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pGLS3-5xHRE-p53(K120R)

    Plasmid

    #72554

    Purpose

    Hypoxia induced mutant p53. Contains the HRE from VEGF sequence (5 repeats) upstream of p53 K120R.

    Depositor

    Ester Hammond

    Article

    Leszczynska et al J Clin Invest. 2015 Jun;125(6):2385-98.

    Insert

    p53 (TP53 Human)
    

    Use

    Tags

    5XHRE

    Expression

    Mammalian

    Mutation

    K120R

    Promoter

    E1B minimal promoter

    Available since

    April 12, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pRetroX-TRE3G-IRSp53 P278D P281D

    Plasmid

    #221320

    Purpose

    Dox-inducible expression of IRSp53 mutant in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG

    Expression

    Mutation

    P278D P281D

    Promoter

    TRE3G

    Available since

    July 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pMSCV-FKBP-IRSp53(pLxIS) S269A

    Plasmid

    #221269

    Purpose

    Expression of IRSp53 pLxIS mutant in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 pLxIS (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG-4xFKBP

    Expression

    Mutation

    S269A

    Promoter

    Available since

    July 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. MG15-luc (mut p53 binding sites)

    Plasmid

    #16443

    Depositor

    Bert Vogelstein

    Article

    el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25.

    Insert

    p53-binding site (mutant) (TP53 )
    

    Use

    Luciferase

    Tags

    luciferase

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 12, 2008

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. MG15-gal (mut p53 binding sites)

    Plasmid

    #16447

    Depositor

    Bert Vogelstein

    Article

    el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25.

    Insert

    p53-binding site (mutant) (TP53 )
    

    Use

    Beta-gal reporter

    Tags

    beta-gal

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 12, 2008

    Availability

    Academic Institutions and Nonprofits only

15. pLX313-TP53-P278A

    Plasmid

    #118015

    Purpose

    Constitutive expression of mutant human Tumor Protein p53 (TP53)

    Depositor

    William Hahn, David Root

    Article

    Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

    Insert

    TP53 (TP53 Human)
    

    Use

    Lentiviral

    Tags

    V5

    Expression

    Mammalian

    Mutation

    p.Pro278Ala

    Promoter

    EF1alpha

    Available since

    Oct. 29, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pGLS3-5xHRE-p53(K120R/K164R)

    Plasmid

    #72556

    Purpose

    Hypoxia induced mutant p53. Contains the HRE from VEGF sequence (5 repeats) upstream of p53 K120R/K164R.

    Depositor

    Ester Hammond

    Article

    Leszczynska et al J Clin Invest. 2015 Jun;125(6):2385-98.

    Insert

    p53 (TP53 Human)
    

    Use

    Tags

    5XHRE

    Expression

    Mammalian

    Mutation

    K120R/K164R

    Promoter

    E1B minimal promoter

    Available since

    March 15, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. HA-HIF2α P405A/P531A/N847A-pBabe-Puro

    Plasmid

    #25956

    Depositor

    William Kaelin

    Article

    Yan et al Mol Cell Biol. 2007 Mar . 27(6):2092-102

    Insert

    Hypoxia inducible factor 2 alpha (EPAS1 Human)
    

    Use

    Retroviral

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    cDNA changed amino acids: Proline 405 to Alanin…

    Promoter

    Available since

    Oct. 19, 2010

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. HA-HIF2α P405A/P531A/N847Q-pBabe-Puro

    Plasmid

    #25948

    Depositor

    William Kaelin

    Article

    Yan et al Mol Cell Biol. 2007 Mar . 27(6):2092-102

    Insert

    Hypoxia inducible factor 2 alpha (EPAS1 Human)
    

    Use

    Retroviral

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    cDNA changed amino acids: Proline 405 to Alanin…

    Promoter

    Available since

    Sept. 20, 2010

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. HA-HIF2α P405A/P531A Δ820-870-pBabe-Puro

    Plasmid

    #25949

    Depositor

    William Kaelin

    Article

    Yan et al Mol Cell Biol. 2007 Mar . 27(6):2092-102

    Insert

    Hypoxia inducible factor 2 alpha (EPAS1 Human)
    

    Use

    Retroviral

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    cDNA changed amino acids: Proline 405 to Alanin…

    Promoter

    Available since

    Oct. 4, 2010

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. HA-HIF2α bHLH* P405A/P531A Δ820-870-pBabe-Puro

    Plasmid

    #25957

    Depositor

    William Kaelin

    Article

    Yan et al Mol Cell Biol. 2007 Mar . 27(6):2092-102

    Insert

    Hypoxia inducible factor 2 alpha (EPAS1 Human)
    

    Use

    Retroviral

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    cDNA changed amino acids: Proline 405 to Alanin…

    Promoter

    Available since

    Sept. 22, 2010

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. sox10:PDGFRA mutant

    Plasmid

    #98697

    Purpose

    I-SceI meganuclease-mediated human PDGFRA mutant transgenesis in zebrafish

    Depositor

    Thomas Look

    Article

    Ki et al Oncogene. 2017 Feb 23;36(8):1058-1068. d

    Insert

    PDGFRA (PDGFRA Human)
    

    Use

    Zebrafish expression

    Tags

    Expression

    Mutation

    exon 8 and 9 deletion

    Promoter

    Available since

    July 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pGL3-CMV-p85a 3'UTR mutant

    Plasmid

    #51393

    Depositor

    Narry Kim

    Article

    Park et al Nat Struct Mol Biol. 2009 Jan;16(1):23-9

    Insert

    p85alpha 3'UTR (PIK3R1 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mutation

    miR-29 binding site mutant

    Promoter

    CMV

    Available since

    March 31, 2014

    Availability

    Academic Institutions and Nonprofits only

23. pGL3-CMV-Cdc42 3'UTR mutant (position 577-599)

    Plasmid

    #51391

    Depositor

    Narry Kim

    Article

    Park et al Nat Struct Mol Biol. 2009 Jan;16(1):23-9

    Insert

    NM_001039802.1 (CDC42 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mutation

    miR-29 binding site mutant (position 577-599)

    Promoter

    CMV

    Available since

    March 31, 2014

    Availability

    Academic Institutions and Nonprofits only

24. pGL3-CMV-Cdc42 3'UTR mutant (position 577-599 and 997-1019)

    Plasmid

    #51390

    Depositor

    Narry Kim

    Article

    Park et al Nat Struct Mol Biol. 2009 Jan;16(1):23-9

    Insert

    NM_001039802.1 (CDC42 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mutation

    miR-29 binding site mutant (position 577-599, 997…

    Promoter

    CMV

    Available since

    March 31, 2014

    Availability

    Academic Institutions and Nonprofits only

25. pX68

    Plasmid

    #46857

    Purpose

    OP Hupki-puro2A-A138V plasmid to indroduce mutant p53 to PLF ESC or MEFs by IMCE

    Depositor

    Monica Hollstein

    Article

    Wei et al Cell Cycle. 2011 Apr 15;10(8):1261-70. E

    Insert

    attB-Puro-2A and Hupki p53 A138V (TP53 Mouse, Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    p53 A138V

    Promoter

    Available since

    Aug. 22, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pX62

    Plasmid

    #46854

    Purpose

    TOP Hupki-puro2A-G245S plasmid to introduce mutant p53 to PLF ESC or MEFs by IMCE

    Depositor

    Monica Hollstein

    Article

    Wei et al Cell Cycle. 2011 Apr 15;10(8):1261-70. E

    Insert

    attB-Puro-2A and Hupki p53 G245S (TP53 Mouse, Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    G245S

    Promoter

    Available since

    Aug. 22, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pBabe 12S E1A

    Plasmid

    #18742

    Depositor

    Scott Lowe

    Article

    Samuelson et al Proc Natl Acad Sci U S A. 1997 Oct 28. 9

    Insert

    12S E1A
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 3, 2008

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pLPC 12S E1A

    Plasmid

    #18740

    Depositor

    Scott Lowe

    Article

    Samuelson et al Proc Natl Acad Sci U S A. 1997 Oct 28. 9

    Insert

    12S E1A
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 3, 2008

    Availability

    Academic Institutions and Nonprofits only

29. pBABEneo mt T Ag

    Plasmid

    #133713

    Purpose

    Large T antigen mutant form in pBABEneo vector for mammalian expression.

    Depositor

    James A. DeCaprio

    Insert

    SV40gp6 (SV40gp6 SV40)
    

    Use

    Retroviral

    Tags

    Expression

    Mutation

    aa 1-354 of T antigen (including aa 1-130); no p5…

    Promoter

    Available since

    March 31, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pDD2706

    Plasmid

    #175080

    Purpose

    Mammalian expression of Flag-tagged KSHV ORF45 RC mutant

    Depositor

    Dirk Dittmer

    Article

    Alzhanova et al J Virol. 2021 Nov 9;95(23):e0145921. doi

    Insert

    KSHV ORF45 (ORF45 Kaposi's sarcoma-associated herpesvirus 8)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    RC mutant; sequence mutation: GCGGCCGCAGCGCA

    Promoter

    Available since

    Feb. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge