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pSH1/M-FGFR1-Fv-Fvls-E

Plasmid

#15285

Depositor

David Spencer

Article

Freeman et al Cancer Res. 2003 Oct 1. 63(19):6237-43.

Insert

FGFR1 kinase, FKBP12v36 (Fgfr1 Mouse)

Use

Tags

HA epitope and Myristoylation-targeting domain c-…

Expression

Mammalian

Mutation

FGFR1 cytoplasmic domain FKBP12 F36V

Promoter

Available since

July 12, 2007

Availability

Academic Institutions and Nonprofits only

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R777-E083 Hs.FGFR1

Plasmid

#70367

Purpose

Gateway ORF clone of human FGFR1 [NM_001174063.1] with stop codon (for native or N-terminal fusions)

Depositor

Dominic Esposito

Insert

FGFR1 (FGFR1 Human)

Use

Gateway entry clone

Tags

Expression

Mutation

Promoter

Available since

March 1, 2016

Availability

Academic Institutions and Nonprofits only

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pCMV-OptoFGFR1-D387A

Plasmid

#59778

Purpose

Expresses optoFGFR1 with mutation in PHR to suppress homointeraction, thus cannot be activated by light

Depositor

Won Do Heo

Article

Kim et al Chem Biol. 2014 Jul 17;21(7):903-12. doi

Insert

OptoFGFR1-D387A (FGFR1 Human, Mustard Weed)

Use

Tags

mCitrine

Expression

Mammalian

Mutation

Promoter

CMV

Available since

June 26, 2019

Availability

Academic Institutions and Nonprofits only

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pCMV-OptoFGFR1-Y766F

Plasmid

#59777

Purpose

Expresses optoFGFR1 with mutation in PLC-gamma binding phosphotyrosine site of FGFR1

Depositor

Won Do Heo

Article

Kim et al Chem Biol. 2014 Jul 17;21(7):903-12. doi

Insert

OptoFGFR1-Y766F (FGFR1 Human, Mustard Weed)

Use

Tags

mCitrine

Expression

Mammalian

Mutation

Promoter

CMV

Available since

June 26, 2019

Availability

Academic Institutions and Nonprofits only

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FGFR1 gRNA (BRDN0001145494)

Plasmid

#76067

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR1 (FGFR1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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OptoOFF-MxCBD-mFGFR1_623

Plasmid

#105825

Purpose

Expresses OptoOFF-MxCBD-mFGFR1 (light-inactivated receptor tyrosine kinase)

Depositor

Harald Janovjak

Article

Kainrath et al Angew Chem Int Ed Engl. 2017 Apr 10;56(1

Insert

OptoOFF-MxCBD-mFGFR1

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

April 26, 2018

Availability

Academic Institutions and Nonprofits only

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FGFR1 gRNA (BRDN0001146517)

Plasmid

#76069

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR1 (FGFR1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
OptoOFF-TtCBD-mFGFR1_624

Plasmid

#105826

Purpose

Expresses OptoOFF-TtCBD-mFGFR1 (light-inactivated receptor tyrosine kinase)

Depositor

Harald Janovjak

Article

Kainrath et al Angew Chem Int Ed Engl. 2017 Apr 10;56(1

Insert

OptoOFF-TtCBD-mFGFR1

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

April 26, 2018

Availability

Academic Institutions and Nonprofits only

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pBS cFgfr1 (CT#220)

Plasmid

#13905

Depositor

Cliff Tabin

Article

Brent et al Development. 2004 Aug . 131(16):3885-96.

Insert

Fgfr1 (FGFR1 Chicken)

Use

Tags

Expression

Bacterial

Mutation

Promoter

Available since

Feb. 9, 2007

Availability

Academic Institutions and Nonprofits only
pAG150 FGFR1 3'UTR

Plasmid

#12008

Depositor

David Bartel

Article

Farh et al Science. 2005 Dec 16. 310(5755):1817-21.

Insert

N15 3'UTR (FGFR1 Human)

Use

Luciferase

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 8, 2006

Availability

Academic Institutions and Nonprofits only

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pCS2-Opto-zFGFR1a

Plasmid

#232639

Purpose

Zebrafish FGFR1a receptor kinase domain fused to VfLOV

Depositor

Katherine Rogers

Insert

zFGFR1a kinase domain + VfLOV domain

Use

Tags

Expression

Mutation

Promoter

Available since

April 22, 2025

Availability

Academic Institutions and Nonprofits only

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FGFR1 gRNA (BRDN0001146877)

Plasmid

#76068

Purpose

3rd generation lentiviral gRNA plasmid targeting human FGFR1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

FGFR1 (FGFR1 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
pHR FGFR1-CD3ε-FusionRed

Plasmid

#188632

Purpose

Human FGFR1 labeled with CD3ε ITAMs for monitoring with CD3ε/ZtSH2 pYtag biosensor

Depositor

Jared Toettcher

Article

Farahani et al eLife. 2023 May 22;12:e82863. doi: 10.75

Insert

FGFR1 (FGFR1 Human, Synthetic)

Use

Lentiviral

Tags

CD3ε-FusionRed

Expression

Mammalian

Mutation

Promoter

SFFV

Available since

Aug. 22, 2022

Availability

Academic Institutions and Nonprofits only

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R777-E084 Hs.FGFR1-nostop

Plasmid

#70368

Purpose

Gateway ORF clone of human FGFR1 [NM_001174063.1] without stop codon (for C-terminal fusions)

Depositor

Dominic Esposito

Insert

FGFR1 (FGFR1 Human)

Use

Gateway entry clone

Tags

Expression

Mutation

Promoter

Available since

March 1, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
pLenti-CMV-Blast-DNFGFR1-HA

Plasmid

#130887

Purpose

Expresses dominant negative mutant mouse FGFR1

Depositor

Gian-Paolo Dotto

Article

Bordignon et al Cell Rep. 2019 Aug 27;28(9):2358-2372.e6

Insert

Fgfr1 (Fgfr1 Mouse)

Use

Tags

HA-tag

Expression

Mammalian

Mutation

Dominant Negative receptor lacking cytosolic cata…

Promoter

Available since

Sept. 4, 2019

Availability

Academic Institutions and Nonprofits only

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pAG182 FGFR1 3'UTR mut

Plasmid

#12009

Depositor

David Bartel

Article

Farh et al Science. 2005 Dec 16. 310(5755):1817-21.

Insert

N15 3'UTR mut (FGFR1 Human)

Use

Luciferase

Tags

Expression

Mammalian

Mutation

Mutations in microRNA recognition sites (seed mat…

Promoter

Available since

June 8, 2006

Availability

Academic Institutions and Nonprofits only
pWZL Neo Myr Flag FGFR1

Plasmid

#20486

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

FGFR1 (FGFR1 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Mutation

Promoter

Available since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only

Enlarge
pD649-HAsp-FGFR1-Fc(DAPA)-AviTag-6xHis

Plasmid

#156800

Purpose

Mammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.

Depositor

Chris Garcia

Article

Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

Insert

FGFR1 (FGFR1 Human)

Use

Tags

Fc(DAPA)-AviTag-6xHis

Expression

Mammalian

Mutation

Fc region of human IgG contains D265A and P329A m…

Promoter

CMV/SP6

Available since

March 8, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
pD649-HAsp-FGFR1-COMP5AP-AviTag-9xHis

Plasmid

#157364

Purpose

Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

Depositor

Chris Garcia

Article

Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

Insert

FGFR1 (FGFR1 Human)

Use

Tags

COMP5AP-AviTag-9xHis

Expression

Mammalian

Mutation

Promoter

CMV/SP6

Available since

March 8, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
MoFGFR31b-ires neo

Plasmid

#86495

Purpose

mamalian cell expression of FGFR3-FGFR1 chimera

Depositor

David Ornitz

Article

Ornitz et al J Biol Chem. 1996 Jun 21;271(25):15292-7

Insert

FgfrR31 IIIb 15C8 (Fgfr3, Fgfr1 Mouse)

Use

Tags

Expression

Mammalian

Mutation

FGFR3-FGFR1 chimera

Promoter

Moloney murine leukemia virus LTR

Available since

Feb. 2, 2017

Availability

Academic Institutions and Nonprofits only

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