We narrowed to 1,037 results for: David Sabatini

1. LentiCRISPR-sgC1orf27-2

   Plasmid

   #86131

   Purpose

   Lentiviral vector expressing Cas9 and an sgRNA targeting C1orf27

   Depositor

   David Sabatini

   Article

   Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

   Insert

   sgRNA 2 targeting C1orf27 (C1orf27 )
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Feb. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. lentiCRISPR - Amplicon, JAK2 sgRNA 2

   Plasmid

   #70660

   Purpose

   Expresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and an intergenic JAK2 amplicon-targeting sgRNA element from U6 promoter. Lentiviral backbone

   Depositor

   David Sabatini

   Article

   Wang et al Science. 2015 Oct 15. pii: aac7041.

   Insert

   sgRNA against JAK2 amplicon found in AML-derived HEL cell line (JAK2 )
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 29, 2015

   Availability

   Academic Institutions and Nonprofits only

3. myc GbetaL mutant 5

   Plasmid

   #8479

   Depositor

   David Sabatini

   Article

   Kim et al Mol Cell 2003 Apr;11(4):895-904.

   Insert

   GbetaL (MLST8 Human)
   

   Use

   Tags

   myc

   Expression

   Mammalian

   Mutation

   G192D

   Promoter

   Available since

   April 20, 2006

   Availability

   Academic Institutions and Nonprofits only

4. pRK5-HA-Sestrin2-E451A

   Plasmid

   #73674

   Purpose

   overexpression

   Depositor

   David Sabatini

   Article

   Wolfson et al Science. 2016 Jan 1;351(6268):43-8. doi:

   Insert

   Sesn2 (SESN2 Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   E451A changed Glutamate 451 to Alanine

   Promoter

   CMV

   Available since

   March 30, 2016

   Availability

   Academic Institutions and Nonprofits only

5. pRK5-HA CASTOR2 ACT2

   Plasmid

   #84494

   Purpose

   overexpression of CASTOR2 ACT2 domain (aa 171-end)

   Depositor

   David Sabatini

   Article

   Chantranupong et al Cell. 2016 Mar 24;165(1):153-64. doi: 10

   Insert

   CASTOR2 ACT2 (GATSL2 Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   171-last amino acid

   Promoter

   CMV

   Available since

   Oct. 24, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pRK5-Flag CASTOR2 ACT1

   Plasmid

   #84493

   Purpose

   overexpression of CASTOR2 ACT1 domain (aa 1-171)

   Depositor

   David Sabatini

   Article

   Chantranupong et al Cell. 2016 Mar 24;165(1):153-64. doi: 10

   Insert

   CASTOR2 ACT1 (GATSL2 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   1-171 amino acid

   Promoter

   CMV

   Available since

   Oct. 24, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pRK5-HA CASTOR1 ACT2

   Plasmid

   #84492

   Purpose

   overexpression of CASTOR1 ACT2 domain (aa 169-end)

   Depositor

   David Sabatini

   Article

   Chantranupong et al Cell. 2016 Mar 24;165(1):153-64. doi: 10

   Insert

   CASTOR1 ACT2 (GATSL3 Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   169-last amino acid

   Promoter

   CMV

   Available since

   Oct. 24, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pRK5-Flag CASTOR1 ACT1

   Plasmid

   #84491

   Purpose

   overexpression of CASTOR1 ACT1 domain (aa 1-169)

   Depositor

   David Sabatini

   Article

   Chantranupong et al Cell. 2016 Mar 24;165(1):153-64. doi: 10

   Insert

   CASTOR1 ACT1 (GATSL3 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   1-169 amino acid

   Promoter

   CMV

   Available since

   Oct. 24, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pS2-FLAG-Sestrin2-E451A

   Plasmid

   #73679

   Purpose

   overexpression

   Depositor

   David Sabatini

   Article

   Wolfson et al Science. 2016 Jan 1;351(6268):43-8. doi:

   Insert

   Sesn2 (SESN2 Human)
   

   Use

   Lentiviral

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   E451A changed Glutamate 451 to Alanine

   Promoter

   Sesn2

   Available since

   April 12, 2016

   Availability

   Academic Institutions and Nonprofits only

10. lentiCRISPR - C3orf17 sgRNA 1

    Plasmid

    #70652

    Purpose

    Expresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and a C3orf17 targeting synthetic single-guide RNA (sgRNA) element from U6 promoter. Lentiviral backbone.

    Depositor

    David Sabatini

    Article

    Wang et al Science. 2015 Oct 15. pii: aac7041.

    Insert

    sgRNA against C3orf17
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 29, 2015

    Availability

    Academic Institutions and Nonprofits only

11. pRK5-HA-Sestrin2-L261A

    Plasmid

    #73672

    Purpose

    overexpression

    Depositor

    David Sabatini

    Article

    Wolfson et al Science. 2016 Jan 1;351(6268):43-8. doi:

    Insert

    Sesn2 (SESN2 Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    L261A changed Leucine 261 to Alanine

    Promoter

    CMV

    Available since

    March 30, 2016

    Availability

    Academic Institutions and Nonprofits only

12. pRK5 HA-GST-Presc-mAkt1 (S473T)

    Plasmid

    #48806

    Purpose

    expresses mutant Akt1

    Depositor

    David Sabatini

    Article

    Kang et al Science. 2013 Jul 26;341(6144):1236566.

    Insert

    Akt1 (Akt1 Mouse)
    

    Use

    Tags

    HA-GST-Presc

    Expression

    Mammalian

    Mutation

    S473T

    Promoter

    CMV

    Available since

    May 2, 2014

    Availability

    Academic Institutions and Nonprofits only

13. pLentiCRISPR sgFTCD_1

    Plasmid

    #102312

    Purpose

    genetic depletion of FTCD

    Depositor

    David Sabatini

    Article

    Kanarek et al Nature. 2018 Jul 11. pii: 10.1038/s41586

    Insert

    sgFTCD_1 (FTCD Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pLentiCRISPR sgFTCD_2

    Plasmid

    #102313

    Purpose

    genetic depletion of FTCD

    Depositor

    David Sabatini

    Article

    Kanarek et al Nature. 2018 Jul 11. pii: 10.1038/s41586

    Insert

    sgFTCD_2 (FTCD Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. lentiCRISPR - C9orf114 sgRNA 1

    Plasmid

    #70655

    Purpose

    Expresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and a C9orf114 targeting synthetic single-guide RNA (sgRNA) element from U6 promoter. Lentiviral backbone.

    Depositor

    David Sabatini

    Article

    Wang et al Science. 2015 Oct 15. pii: aac7041.

    Insert

    sgRNA against C9orf114
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 29, 2015

    Availability

    Academic Institutions and Nonprofits only

16. lentiCRISPR - C9orf114 sgRNA 2

    Plasmid

    #70654

    Purpose

    Expresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and a C9orf114 targeting synthetic single-guide RNA (sgRNA) element from U6 promoter. Lentiviral backbone.

    Depositor

    David Sabatini

    Article

    Wang et al Science. 2015 Oct 15. pii: aac7041.

    Insert

    sgRNA against C9orf114
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 29, 2015

    Availability

    Academic Institutions and Nonprofits only

17. myc GbetaL mutant 7

    Plasmid

    #8481

    Depositor

    David Sabatini

    Article

    Kim et al Mol Cell 2003 Apr;11(4):895-904.

    Insert

    GbetaL (MLST8 Human)
    

    Use

    Tags

    myc

    Expression

    Mammalian

    Mutation

    F320S

    Promoter

    Available since

    April 20, 2006

    Availability

    Academic Institutions and Nonprofits only

18. myc GbetaL mutant 2

    Plasmid

    #8478

    Depositor

    David Sabatini

    Article

    Kim et al Mol Cell 2003 Apr;11(4):895-904.

    Insert

    GbetaL (MLST8 Human)
    

    Use

    Tags

    myc

    Expression

    Mammalian

    Mutation

    S72D

    Promoter

    Available since

    April 20, 2006

    Availability

    Academic Institutions and Nonprofits only

19. HA GST deltaCT S6K1 pRK5

    Plasmid

    #8468

    Depositor

    David Sabatini

    Article

    Ali et al J Biol Chem 2005 Apr 4;.

    Insert

    delta CT p85 s6k1 (Rps6kb1 Rat)
    

    Use

    Tags

    ha/gst

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Dec. 7, 2005

    Availability

    Academic Institutions and Nonprofits only

20. pRK5-HA-SZT2 2241-end

    Plasmid

    #87040

    Purpose

    mammalian expression of SZT2 fragment

    Depositor

    David Sabatini

    Article

    Wolfson et al Nature. 2017 Feb 15. doi: 10.1038/nature

    Insert

    SZT2 (SZT2 Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    AA 2241-end

    Promoter

    CMV

    Available since

    March 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge