We narrowed to 31,661 results for: uros

Showing: 8161 - 8200 of 31661 results

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pHIVT9-NAT-3xFlag-SMARCAL1

Plasmid

#246935

Purpose

Lentiviral vector that expresses wildtype Flag-tagged SMARCAL1

Depositor

Daniel Durocher

Article

Feng et al Mol Cell. 2024 Dec 5;84(23):4522-4537.e7

Insert

SMARCAL1 (SMARCAL1 Human)

Use

Lentiviral

Tags

3XFLAG

Expression

Mammalian

Promoter

EF-1-alpha promoter

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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MSCV-IRES-Thy1.1-Aoah

Plasmid

#233141

Purpose

Thy1.1 and Aoah overexpression

Depositor

Peng Jiang

Article

Gong et al Cell. 2025 Jul 24:S0092-8674(25)00793-7.

Insert

Acyloxyacyl hydrolase (Aoah Mouse)

Use

Lentiviral

Available Since

Nov. 17, 2025

Availability

Academic Institutions and Nonprofits only

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sg_Snrnp48_i1-ipUSEPR-TR657

Plasmid

#228925

Purpose

Knockdown of Snrnp48 in mammalian cells

Depositor

Sika Zheng

Article

Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

Insert

sg_Snrnp48_i1 (Snrnp48 Mouse)

Use

Lentiviral

Available Since

April 16, 2025

Availability

Academic Institutions and Nonprofits only

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hSyn-HA-PGRN-IRES2-GFP

Plasmid

#234876

Purpose

Lentiviral plasmid expressing HA-tagged human progranulin followed by IRES2-GFP.

Depositor

Andrew Arrant

Article

Davis et al J Biol Chem. 2021 Sep;297(3):100993. doi

Insert

Progranulin (GRN Human)

Use

Lentiviral

Tags

HA tag

Expression

Mammalian

Promoter

hSYn

Available Since

April 16, 2025

Availability

Academic Institutions and Nonprofits only

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pMXs-uORFx6-mNgn2x3HA-P2A-mRuby2

Plasmid

#233168

Purpose

Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

Depositor

Kate Galloway

Article

Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

Insert

mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)

Use

Retroviral

Tags

x3HA

Expression

Mammalian

Available Since

March 13, 2025

Availability

Academic Institutions and Nonprofits only

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pMXs-uORFwx1-mNgn2x3HA-P2A-mRuby2

Plasmid

#233164

Purpose

Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

Depositor

Kate Galloway

Article

Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

Insert

mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)

Use

Retroviral

Tags

x3HA

Expression

Mammalian

Available Since

March 13, 2025

Availability

Academic Institutions and Nonprofits only

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pMXs-uORFx1-mNgn2x3HA-P2A-mRuby2

Plasmid

#233165

Purpose

Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

Depositor

Kate Galloway

Article

Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

Insert

mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)

Use

Retroviral

Tags

x3HA

Expression

Mammalian

Available Since

March 13, 2025

Availability

Academic Institutions and Nonprofits only

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pMXs-uORFx2-mNgn2x3HA-P2A-mRuby2

Plasmid

#233166

Purpose

Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

Depositor

Kate Galloway

Article

Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

Insert

mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)

Use

Retroviral

Tags

x3HA

Expression

Mammalian

Available Since

March 13, 2025

Availability

Academic Institutions and Nonprofits only

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pMXs-uORFx3-mNgn2x3HA-P2A-mRuby2

Plasmid

#233167

Purpose

Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

Depositor

Kate Galloway

Article

Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

Insert

mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)

Use

Retroviral

Tags

x3HA

Expression

Mammalian

Available Since

March 13, 2025

Availability

Academic Institutions and Nonprofits only

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pPB9P3

Plasmid

#210034

Purpose

Contains cloning site for PE3/3b prime editing gRNA constructs, inducible prime editor 2, rtTA-T2A-puro

Depositor

Michael Talkowski

Article

Nuttle et al Cell Rep Methods. 2023 Dec 5:100672. doi

Inserts

prime editor 2
rtta-T2A-puro

Use

CRISPR

Tags

SV40 NLS

Expression

Mammalian

Promoter

EF-1α and TRE3G

Available Since

Feb. 6, 2025

Availability

Academic Institutions and Nonprofits only

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sg_Tada3_i3-ipUSEPR-TR657

Plasmid

#228915

Purpose

Knockdown of Tada3 in mammalian cells

Depositor

Sika Zheng

Article

Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

Insert

sg_Tada3_i3 (Tada3 Mouse)

Use

Lentiviral

Available Since

Jan. 7, 2025

Availability

Academic Institutions and Nonprofits only

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sg_Tada3_i5-ipUSEPR-TR657

Plasmid

#228916

Purpose

Knockdown of Tada3 in mammalian cells

Depositor

Sika Zheng

Article

Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

Insert

sg_Tada3_i3 (Tada3 Mouse)

Use

Lentiviral

Available Since

Jan. 7, 2025

Availability

Academic Institutions and Nonprofits only

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sg_Snrnp48_i4-ipUSEPR-TR657

Plasmid

#228926

Purpose

Knockdown of Snrnp48 in mammalian cell

Depositor

Sika Zheng

Article

Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

Insert

sg_Snrnp48_i4 (Snrnp48 Mouse)

Use

Lentiviral

Available Since

Jan. 7, 2025

Availability

Academic Institutions and Nonprofits only

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pCAG_SRGAP2A_SH3(W765A)_GFP

Plasmid

#222616

Purpose

Expresses a form of full length SRGAP2 with one point mutation (W765A) in the SH3 domain abrogating its ability to bind to Gephyrin.

Depositor

Franck Polleux

Article

Fossati et al Neuron. 2016 Jul 20;91(2):356-69. doi: 1

Insert

SRGAP2 (SRGAP2 Human)

Tags

EGFP

Expression

Mammalian

Mutation

Point mutation W765A (SH3 domain)

Available Since

Oct. 9, 2024

Availability

Academic Institutions and Nonprofits only

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pCAG_SRGAP2A_SH3(W765A)_HA

Plasmid

#222614

Purpose

Expresses a form of full length SRGAP2 with one point mutation (W765A) in the SH3 domain abrogating its ability to bind to Gephyrin.

Depositor

Franck Polleux

Article

Fossati et al Neuron. 2016 Jul 20;91(2):356-69. doi: 1

Insert

SRGAP2 (SRGAP2 Human)

Tags

HA

Expression

Mammalian

Mutation

Point mutation W765A (SH3 domain)

Available Since

Oct. 9, 2024

Availability

Academic Institutions and Nonprofits only

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pCAG SRGAP2A_EVH1(P339L F342C)

Plasmid

#222613

Purpose

Expresses a form of full length SRGAP2 with two point mutations (P339L and F342C) that abrogate EVH1 binding site for Homer1

Depositor

Franck Polleux

Article

Fossati et al Neuron. 2016 Jul 20;91(2):356-69. doi: 1

Insert

SRGAP2 (SRGAP2 Human)

Tags

EGFP

Expression

Mammalian

Mutation

Point mutations P339L and F342C

Available Since

Oct. 9, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pLKO.1 mTagBFP2 rat DJ-1 shRNA

Plasmid

#222870

Purpose

Expresses mTagBFP2 along with an shRNA against rat DJ-1

Depositor

Timothy Ryan

Article

Kokotos et al Sci Adv. 2024 Aug 23;10(34):eadn6016. do

Insert

DJ-1 shRNA (Park7 Rat)

Use

Lentiviral and RNAi

Expression

Mammalian

Promoter

U6

Available Since

July 9, 2024

Availability

Academic Institutions and Nonprofits only

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pLKO-Tet-On-ARNT-shRNA1

Plasmid

#166910

Purpose

Lentivirus for inducible knockdown of human ARNT

Depositor

Roland Friedel

Article

Halawani et al Nat Commun. 2023 Aug 24;14(1):5165. doi:

Insert

ARNT shRNA (ARNT Human)

Use

Lentiviral

Expression

Mammalian

Available Since

March 14, 2024

Availability

Academic Institutions and Nonprofits only

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pLKO-Tet-On-ARNT-shRNA2

Plasmid

#166911

Purpose

Lentivirus for inducible knockdown of human ARNT

Depositor

Roland Friedel

Article

Halawani et al Nat Commun. 2023 Aug 24;14(1):5165. doi:

Insert

ARNT shRNA (ARNT Human)

Use

Lentiviral

Expression

Mammalian

Available Since

March 14, 2024

Availability

Academic Institutions and Nonprofits only

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pLKO-Tet-On-ARNT-shRNA3

Plasmid

#166912

Purpose

Lentivirus for inducible knockdown of human ARNT

Depositor

Roland Friedel

Article

Halawani et al Nat Commun. 2023 Aug 24;14(1):5165. doi:

Insert

ARNT shRNA (ARNT Human)

Use

Lentiviral

Expression

Mammalian

Available Since

March 14, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
Cav2.1 R57A, R59A pMT2

Plasmid

#206112

Purpose

expression of rat Cav2.1 calcium channel with R57A and R59A mutations that prevent G-protein modulation

Depositor

Annette Dolphin

Article

Dahimene et al Neurobiol Dis. 2016 Sep;93:243-56. doi:

Insert

cacna1a (Cacna1a Rat)

Expression

Mammalian

Mutation

R57A, R59A

Promoter

Ad MLP/TPL/SV40

Available Since

Nov. 20, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-GRAB_CRF0.5

Plasmid

#208657

Purpose

Expresses the genetically-encoded fluorescent corticotropin-releasing factor (CRF) sensor GRAB_CRF0.5 in neurons

Depositor

Yulong Li

Article

Wang et al Science. 2023 Nov 17;382(6672):eabq8173.

Insert

GPCR activation based corticotropin-releasing factor (CRF) sensor GRAB_CRF0.5

Use

AAV

Promoter

hSyn

Available Since

Oct. 23, 2023

Availability

Academic Institutions and Nonprofits only

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GFP Cav2.2 D122A pcDNA3

Plasmid

#206068

Purpose

expression of rabbit Cav2.2 calcium channel with a N-terminal GFP tag and a D122A mutation that disrupts the interaction with ?2?-1

Depositor

Annette Dolphin

Article

Page et al J Neurosci. 2004 Jun 9;24(23):5400-9. do

Insert

cacna1b (CACNA1B Rabbit)

Tags

GFP

Expression

Mammalian

Promoter

CMV

Available Since

Oct. 12, 2023

Availability

Academic Institutions and Nonprofits only

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pNM1325

Plasmid

#197144

Purpose

CAGp-Target-AID-2A-BlastR for PiggyBac genomic integration

Depositor

Nozomu Yachie

Article

Ishiguro et al Nat Biotechnol. 2025 May 21. doi: 10.103

Insert

SpCas9-PmCDA1-UGI

Use

CRISPR

Expression

Mammalian

Mutation

SpCas9(D10A)

Promoter

CAG

Available Since

May 9, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-GFP-IRES-hSNCA (S129D)

Plasmid

#185719

Purpose

AAV expression of GFP and human α-Synuclein with S129D mutation from hSyn promoter

Depositor

Jun Ding

Article

Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

Insert

synuclein, alpha (SNCA Human)

Use

AAV

Mutation

Changed Ser 129 to Asp

Promoter

hSyn

Available Since

June 28, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-hSyn-GFP-IRES-hSNCA (S129A)

Plasmid

#185718

Purpose

AAV expression of GFP and human α-Synuclein with S129A mutation from hSyn promoter

Depositor

Jun Ding

Article

Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

Insert

synuclein, alpha (SNCA Human)

Use

AAV

Mutation

Changed Ser 129 to Ala

Promoter

hSyn

Available Since

June 28, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-hSyn-GFP-IRES-mSNCA(1-95)

Plasmid

#185716

Purpose

AAV expression of GFP and C-terminal truncated (1-95 amino acid) mouse α-Synuclein from hSyn promoter

Depositor

Jun Ding

Article

Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

Insert

synuclein, alpha (Snca Mouse)

Use

AAV

Mutation

deleted AA 95-144

Promoter

hSyn

Available Since

June 28, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
Gucy1b2-IRES-nlsCre-IRES-taulacZ-FNF TV

Plasmid

#105196

Purpose

targeting vector to generate a Gucy1b2-IRES-nlsCre-IRES-taulacZ mouse strain.

Depositor

Peter Mombaerts

Article

Koike et al Neuron. 2021 Aug 4;109(15):2469-2484.e7.

Insert

Gucy1b2-IRES-nlsCre-IRES-taulacZ-FNF (Gucy1b2 Mouse)

Use

Mouse Targeting

Available Since

April 4, 2022

Availability

Academic Institutions and Nonprofits only
FUS_LC_charge_RtoK

Plasmid

#139127

Purpose

express FUS LC with hnRNPA2-like charge patterning where all R are changed to K

Depositor

Nicolas Fawzi

Article

Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

Insert

FUS (FUS Human)

Expression

Bacterial

Mutation

Add K and D to FUS LC so it has the same charge p…

Available Since

Dec. 7, 2020

Availability

Academic Institutions and Nonprofits only

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pKLV-gRNA-Bcan-Ntrk1_4

Plasmid

#136413

Purpose

Lentiviral expression of gRNAs targeting intron 13 of murine Bcan and intron 10 of murine Ntrk1. Also constitutively expresses Puromycin linked to TagBFP.

Depositor

Massimo Squatrito

Article

Oldrini et al Nat Commun. 2018 Apr 13;9(1):1466. doi:

Insert

U6_sgRNA(Bcan)_U6_sgRNA(Ntrk1)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available Since

Aug. 10, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
pKLV-gRNA-Myb-Qk_1

Plasmid

#136415

Purpose

Lentiviral expression of gRNAs targeting intron 4 of murine Qk and intron 9 of murine Myb. Also constitutively expresses Puromycin linked to TagBFP.

Depositor

Massimo Squatrito

Article

Oldrini et al Nat Commun. 2018 Apr 13;9(1):1466. doi:

Insert

U6_sgRNA(Myb)_U6_sgRNA(Qk)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available Since

Aug. 10, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
pLenti-CMV-Fyn-cGASΔN-HA

Plasmid

#130922

Purpose

Expresses human cGASΔN (aa160-522)-HA with an N terminal fusion of the Fyn dual acylation motif (aa1-16); Puromycin selection marker

Depositor

Jonathan Kagan

Article

Barnett et al Cell. 2019 Mar 7;176(6):1432-1446.e11. d

Insert

Fyn-ΔNcGAS

Tags

HA

Expression

Mammalian

Mutation

cGAS N terminus (aa1-159) replaced with the dual …

Promoter

CMV

Available Since

Aug. 27, 2019

Availability

Academic Institutions and Nonprofits only

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pTBL405 CHYRON1 integration construct

Plasmid

#126442

Purpose

To integrate the CHYRON1 locus at HEK293site3.

Depositor

Chang Liu

Article

Loveless et al Nat Chem Biol. 2021 Jun;17(6):739-747. d

Inserts

pU6-CHYRON1 hgRNA
pCMV-puro

Expression

Mammalian

Mutation

The SpCas9 sgRNA constant region is mutated to ma…

Promoter

CMV and human U6

Available Since

June 5, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pJet-CMV-CD52-bglpA

Plasmid

#89704

Purpose

Human CD52 expression plasmid with short polyA

Depositor

Dmitriy Mazurov

Article

Zotova et al Sci Rep. 2019 Feb 28;9(1):3132. doi: 10.

Insert

CMV-CD52-bglpA (CD52 Human)

Expression

Mammalian

Promoter

CMV

Available Since

March 1, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
MSCV-PIG-N3FLAG-TAF12

Plasmid

#105593

Purpose

retrovirally express mouse TAF12 with 3*FLAG tag at N terminal, GFP marker and puro resistance

Depositor

Christopher Vakoc

Article

Xu et al Cancer Cell. 2018 Jan 8;33(1):13-28.e8.

Insert

full length TAF12 with silent mutations, making it resistant to TAF12 shRNA#364 (Taf12 Mouse)

Use

Retroviral

Tags

3*FLAG

Expression

Mammalian

Mutation

silent mutations to make it resistant to the targ…

Promoter

MSCV-LTR

Available Since

May 1, 2018

Availability

Academic Institutions and Nonprofits only

Enlarge
MSCV-PIG-N3FLAG-TAF12(50-130)

Plasmid

#105595

Purpose

retrovirally express mouse TAF12 HFD with 3*FLAG tag at N terminal, GFP marker and puro resistance

Depositor

Christopher Vakoc

Article

Xu et al Cancer Cell. 2018 Jan 8;33(1):13-28.e8.

Insert

TAF12 (AA 50-130)- histone fold domain-HFD (Taf12 Mouse)

Use

Retroviral

Tags

3*FLAG

Expression

Mammalian

Mutation

truncation fragments containing aa (50-130), and …

Promoter

MSCV-LTR

Available Since

Feb. 15, 2018

Availability

Academic Institutions and Nonprofits only

Enlarge
PRKCG gRNA (BRDN0001147740)

Plasmid

#76898

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKCG

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKCG (PRKCG Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
PRKCG gRNA (BRDN0001146492)

Plasmid

#76899

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKCG

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKCG (PRKCG Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
PRKCG gRNA (BRDN0001146495)

Plasmid

#76900

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKCG

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKCG (PRKCG Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
PRKAR1B gRNA (BRDN0001146606)

Plasmid

#76838

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKAR1B

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKAR1B (PRKAR1B Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge

Showing: 8161 - 8200 of 31661 results

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We narrowed to 31,661 results for: uros