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pLenti/TO/EYFP-P2A-IDH1(HA)

Plasmid

#122482

Purpose

A lentiviral vector (pLenti6.3/TO/DEST) expresses EYFP, P2A, and IDH1 C-terminally tagged with HA

Depositor

Eric Huang

Article

Tiburcio et al Acta Neuropathol. 2018 Feb;135(2):285-29

Insert

isocitrate dehydrogenase 1 (IDH1 Human)

Use

Lentiviral

Tags

HA and P2A

Expression

Mammalian

Promoter

CMV/TO

Available Since

March 21, 2019

Availability

Academic Institutions and Nonprofits only

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flag-hKLF6-4A (1010)

Plasmid

#49489

Purpose

expresses human Flag tagged KLF6 with 4A mutation

Depositor

Scott Friedman

Article

Lang et al Oncogene. 2012 Oct 22. doi: 10.1038/onc.

Insert

KFL6-4A (KLF6 Human)

Tags

Flag

Expression

Mammalian

Mutation

three serines and one tyrosine mutated to alanin…

Promoter

CMV

Available Since

Feb. 18, 2014

Availability

Academic Institutions and Nonprofits only
Lenti-sgFbxw7#1/Cre

Plasmid

#173635

Purpose

Expresses a Fbxw7-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Fbxw7 (Fbxw7 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 18, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgArid1b#2/Cre

Plasmid

#173574

Purpose

Expresses a Arid1b-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Arid1b (Arid1b Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

June 29, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgArid1b#1/Cre

Plasmid

#173573

Purpose

Expresses a Arid1b-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Arid1b (Arid1b Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

June 8, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgArid2#1/Cre

Plasmid

#173575

Purpose

Expresses a Arid2-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Arid2 (Arid2 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

June 8, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgArid2#2/Cre

Plasmid

#173576

Purpose

Expresses a Arid2-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Arid2 (Arid2 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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pDONR207 SARS-CoV-2 NSP1 124A/125A

Plasmid

#164523

Purpose

Gateway-compatible Entry vector, with insert of mutated NSP1 CDS from SARS-CoV-2 isolate Wuhan-Hu-1 (amino acid substitutions R124A/K125A)

Depositor

Mitchell Guttman

Article

Banerjee et al Cell. 2020 Nov 25;183(5):1325-1339.e21.

Insert

NSP1 124A/125A (ORF1ab )

Expression

Mammalian

Mutation

Insert of NSP1 gene's CDS from SARS-CoV-2 is…

Available Since

Feb. 2, 2021

Availability

Academic Institutions and Nonprofits only

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shERK2b-mlpx-neo

Plasmid

#65231

Purpose

encodes a shRNA against ERK2

Depositor

Gerardo Ferbeyre

Article

Deschenes-Simard et al Genes Dev. 2013 Apr 15;27(8):900-15. doi

Insert

shRNA against ERK2 (MAPK1 Human)

Expression

Mammalian

Promoter

PGK

Available Since

Aug. 12, 2015

Availability

Academic Institutions and Nonprofits only

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TET-pLKO.1 PURO shGDF11 #1

Plasmid

#83083

Purpose

Lentiviral shRNA vector for inducible knockdown of human GDF11 (cross reacts with mouse Gdf11)

Depositor

Kevin Janes

Article

Bajikar et al Dev Cell. 2017 Nov 20;43(4):418-435.e13.

Insert

shGDF11 (GDF11, Gdf11 Human, Mouse)

Use

Lentiviral

Expression

Mammalian

Available Since

Feb. 28, 2019

Availability

Academic Institutions and Nonprofits only
pMiR-CIP2A-miR-375-mutA-E

Plasmid

#53754

Purpose

Luciferase reporter assay for CIP2A with point mutation on miR-375 binding sites

Depositor

Edward Chan

Article

Jung et al Mol Biol Cell. 2013 Jun;24(11):1638-48,

Insert

CIP2A (CIP2A Human)

Use

Luciferase

Mutation

Mutation on miR-375 binding site A-E (refer to ci…

Available Since

July 2, 2014

Availability

Academic Institutions and Nonprofits only
pMIRNA1-METTL1-msg6-EIR107-109AAA

Plasmid

#254423

Purpose

Mammalian expression plasmid encoding mutant human METTL1 (sgMETTL1-6-resistant) fused to a 3_FLAG tag.

Depositor

Rui Su

Article

Ren et al Blood 2025; 146 (Supplement 1): 2539. do

Insert

METTL1 (METTL1 Human)

Use

Lentiviral

Tags

3_FLAG

Mutation

EIR107-109AAA

Promoter

CMV

Available Since

April 9, 2026

Availability

Academic Institutions and Nonprofits only

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lenti-hygro-M-sgMettl1-3

Plasmid

#254418

Purpose

Mammalian expression plasmid encoding an sgRNA targeting mouse Mettl1.

Depositor

Rui Su

Article

Ren et al Blood 2025; 146 (Supplement 1): 2539. do

Insert

Mettl1 (Mettl1 Mouse)

Use

Lentiviral

Promoter

U6

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pMIRNA1-METTL1-msg3-EIR107-109AAA

Plasmid

#254422

Purpose

Mammalian expression plasmid encoding mutant human METTL1 (sgMETTL1-3-resistant) fused to a 3_FLAG tag.

Depositor

Rui Su

Article

Ren et al Blood 2025; 146 (Supplement 1): 2539. do

Insert

METTL1 (METTL1 Human)

Use

Lentiviral

Tags

3_FLAG

Mutation

EIR107-109AAA

Promoter

CMV

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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lenti-hygro-M-sgMettl1-4

Plasmid

#254419

Purpose

Mammalian expression plasmid encoding an sgRNA targeting mouse Mettl1.

Depositor

Rui Su

Article

Ren et al Blood 2025; 146 (Supplement 1): 2539. do

Insert

Mettl1 (Mettl1 Mouse)

Use

Lentiviral

Promoter

U6

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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lenti-hygro-sgMETTL1-6

Plasmid

#254417

Purpose

Mammalian expression plasmid encoding an sgRNA targeting human METTL1.

Depositor

Rui Su

Article

Ren et al Blood 2025; 146 (Supplement 1): 2539. do

Insert

METTL1 (METTL1 Human)

Use

Lentiviral

Promoter

U6

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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lenti-hygro-sgMETTL1-3

Plasmid

#254416

Purpose

Mammalian expression plasmid encoding an sgRNA targeting human METTL1.

Depositor

Rui Su

Article

Ren et al Blood 2025; 146 (Supplement 1): 2539. do

Insert

METTL1 (METTL1 Human)

Use

Lentiviral

Promoter

U6

Available Since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

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CRISPRi sgNF2-1

Plasmid

#253094

Purpose

CRISPRi single-guide against NF2

Depositor

Harish Vasudevan

Article

Vasudevan et al Nat Commun. 2024 Jan 12;15(1):477. doi:

Insert

NF2 (NF2 Human)

Use

CRISPR

Available Since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

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pLJC2-TOM20-HK2-3xFLAG

Plasmid

#239245

Purpose

TOM20-HK2 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

TOM20-HK2 (HK2, TOMM20 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains the set of silent mutations descr…

Promoter

CMV

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLJC6-TOM20-HK2-3xFLAG

Plasmid

#239256

Purpose

TOM20-HK2 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

TOM20-HK2 (HK2, TOMM20 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains the set of silent mutations descr…

Promoter

Ubc

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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